Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation? In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients—a Biotech Social Contract. Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including: Why doesn’t insurance make drugs affordable? How can we prevent price-jacking of older drugs? Why are drugs more expensive in America than elsewhere? How can we guarantee that all medicines eventually go generic so they are only temporarily expensive? What systemic failures led to the opioid crisis, and how can we prevent the next one? The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.

    D.E. Boyer takes us on a fascinating journey from the depths of despair to an amazing quantum world where anything is possible. First, we will learn how to defend ourselves against the chaos in our minds, then we will learn how to rekindle the magic in our hearts. Along the way, the wisdom of Socrates and the myth of Narcissus will transform the way we think and feel. Boyer then shows us how the military teaches their Navy Seal recruits how to handle their thoughts and feelings when someone is trying to kill them, so we can better handle our bosses, spouses, and children when it feels like they are trying to kill us. We will also get a glimpse of death through the eyes of someone who sees people die every day, giving us a much greater appreciation for life. With extremely amusing stories from her own life that touch on her dysfunctional upbringing and traumatizing career as an intensive care nurse, Boyer teaches us how to control our anxiety, boost our fragile self-esteem, and get into a state of flow so that we can spend most of our time loving life, rather than dreading it. She also gives us crucial health and nutrition tips so that we can live longer with our newfound peace and joy, and she shows us how to be more successful at life by being a better friend, spouse, and parent. With every step we take on this path, we'll find ourselves flirting with the hidden power of the mind, a power that often lies just beyond most people's reach. Only by mastering the basics of thinking and feeling can we gain access to this power. Once the door is unlocked, we will enter another dimension, a quantum world where time is irrelevant and the magic of our mind is waiting to be found.

    But ambition quickly took wing. The house swelled to 225 rooms and became - until 2012 when it was topped by the home of a billionaire in Mumbai, India – the world’s largest residence ever built for a private citizen. Here’s the story of the house that Vanderbilt built - from the gardens by Frederick Law Olmsted to the John Singer Sargent portraits that adorn its walls.

                Gut Reactions by chemist Simon Quellen Field shows readers how their bodies react to food and the environment and how their brains affect what and how much they eat. It reveals why some diets work for some people but not for others, based on genetics, previous weight history, brain chemistry, environmental cues, and social pressures. It explores how dozens of hormones affect hunger and satiety and interact with the brain and the gut to regulate feeding behavior. And it explains the addictive nature of foods that interact with the same dopamine and opioid receptors in the brain as cocaine, heroin, amphetamines, and nicotine.             Whether you’re looking to lose weight, put on muscle mass, or simply understand how your metabolism or gut microbiome impact your food cravings, Simon Quellen Field has the scientific answers for you.

    All chapters have been thoroughly updated with the latest information as well as new case studies, practice questions, and exercises. This latest edition not only covers the how of clinical testing but also places greater emphasis on the what, why, and when in order to meet the needs of today's clinical laboratorians. A companion Website offers the full text online, objectives, a quiz bank, flashcards, glossary, and appendices for students and improved instructor's resources.

    The set includes thirty-one 30-minute MCAT practice exams with answers and explanations and more than 1,600 MCAT questions.

    At the time we were hoping that our approach of writing a book which would be both accessible without mathematical sophistication and portray these exiting new fields in an authentic manner would find an audience. Now we know it did. We know from many reviews and personal letters that the book is used in a wide range of ways: researchers use it to acquaint themselves, teachers use it in college and university courses, students use it for background reading, and there is also a substantial audience of lay people who just want to know what chaos and fractals are about. Every book that is somewhat technical in nature is likely to have a number of misprints and errors in its first edition. Some of these were caught and brought to our attention by our readers. One of them, Hermann Flaschka, deserves to be thanked in particular for his suggestions and improvements. This second edition has several changes. We have taken out the two appendices from the firstedition. At the time of the first edition Yuval Fishers contribution, which we published as an appendix was probably the first complete expository account on fractal image compression. Meanwhile, Yuvals book Fractal Image Compression: Theory and Application appeared and is now the publication to refer to.

    That substance is vitamin D3. While it is called a vitamin, D3 is really a hormone. It was first used to treat a childhood bone disease called rickets. And, nearly all the research on the benefits of vitamin D3 has been done at doses that are 80 times lower than the optimal doses described in this book. This ground-breaking book is your opportunity to regain your health quickly, safely and easily. In The Optimal Dose, he reveals how vitamin D3 saved his own life when all else failed and explains how this essential vitamin is key to finding answers to your own health questions and challenges.

    In Maine, severely retarded. Small towns across America are being systematically "wiped out" by terrorists and their campaign of germ warfare waged against the U.S. The President's only option seems to be an equally deadly counterattack.

    These kids often have violent outbursts, steal, engage in outlandish lying, play with feces, and hoard food. They are broken children who too often break even the most loving of caregivers. Many parents of these children feel utterly isolated as family, friends, and professionals minimize their struggles. Reactive Attachment Disorder (RAD) - The Essential Guide for Parents is written by a parent who is in the trenches with you. Keri has lived the journey of raising a son with RAD and has navigated the mental health system for over a decade. This is the resource you’ve been waiting for – you won’t find platitudes or false hopes. What you will find is essential information, practical suggestions, and resource recommendations to provide a way forward. If you desperately need help navigating the difficult RAD journey with your child, this book is for you.

    Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Chapters: Woman in the Dunes, Kangaroo Notebook, the Ruined Map, the Face of Another, Inter Ice Age 4. Source: Wikipedia.

    Requiring only basic algebra and trigonometry, the new edition is notable for its readability, learning features and numerous full-color photos and illustrations. A systems approach is used to cover state-of-the-art communications technologies, to best reflect current industry practice. This edition contains greatly expanded and updated material on the Internet, cell phones, and wireless technologies. Practical skills like testing and troubleshooting are integrated throughout. A brand-new Laboratory & Activities Manual provides both hands-on experiments and a variety of other activities, reflecting the variety of skills now needed by technicians. A new Online Learning Center web site is available, with a wealth of learning resources for students. An Instructor Productivity Center CD-ROM features solutions to all problems, PowerPoint lessons, and ExamView test banks for each chapter.

    Known for its carefully developed, thoroughly integrated, step-by-step approach to problem solving, General Chemistry helps students master quantitative skills and build a lasting conceptual understanding of key chemical concepts. The Ninth Edition retains this hallmark approach and builds upon the conceptual focus through key new features and revisions.

    Louis P. Pojman has carefully organized the essays in each section so that they present pro/con dialogues that allow students to compare and contrast the philosophers' positions. Topics covered include the nature of philosophy, the existence of God, immortality, knowledge, the mind-body question, personal identity, free will and determinism, ethics, political philosophy, and the meaning of life. The sixth edition offers selections from Plato, Ren� Descartes, John Locke, David Hume, William James, Bertrand Russell, John Hick, John Hospers, and James Rachels--as well as essays by Aristotle, Thomas Aquinas, Blaise Pascal, Thomas Hobbes, George Berkeley, Immanuel Kant, Gilbert Ryle, Albert Camus, Jean-Paul Sartre, Alvin Plantinga, and many others. In Philosophy: The Quest for Truth, Sixth Edition, Pojman offers substantial introductions to each of the nineteen philosophical problems. In addition, each of the seventy-six readings is accompanied by an individual introduction with a biographical sketch of the philosopher, study questions, and reflective questions that challenge students to analyze and critique the material. Short bibliographies following each major section and a detailed glossary further enhance the text's pedagogical value. Invaluable for introductory courses in philosophy, this highly acclaimed text inspires and guides students' quest for wisdom.New to the Sixth Edition: : * Six selections: William Lane Craig: The Kalam Cosmological Argument and the Anthropic Principle William Rowe: An Analysis of the Ontological Argument Daniel Dennett: Postmodernism and Truth William James: The Dilemma of Determinism Harry Frankfurt: Freedom of the Will and the Concept of a Person John Rawls: The Contemporary Liberal Answer * More exercises in the excursus on logic

    In writing the book James Stewart asked himself:What is essential for a three-semester calculus course for scientists and engineers? Stewart's SINGLE VARIABLE ESSENTIAL CALCULUS: EARLY TRANSCENDENTALS offers a concise approach to teaching calculus, focusing on major concepts and supporting those with precise definitions, patient explanations, and carefully graded problems. SINGLE VARIABLE ESSENTIAL CALCULUS: EARLY TRANSCENDENTALS is only 850 pages-two-thirds the size of Stewart's other calculus texts (CALCULUS, FIFTH EDITION AND CALCULUS, EARLY TRANSCENDENTALS, Fifth Edition)-yet it contains almost all of the same topics. The author achieved this relative brevity mainly by condensing the exposition and by putting some of the features on the website www.StewartCalculus.com. Despite the reduced size of the book, there is still a modern flavor: Conceptual understanding and technology are not neglected, though they are not as prominent as in Stewart's other books. SINGLE VARIABLE ESSENTIAL CALCULUS: EARLY TRANSCENDENTALS has been written with the same attention to detail, eye for innovation, and meticulous accuracy that have made Stewart's textbooks the best-selling calculus texts in the world.