And yet she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose.A twenty-eight-year-old man, vacationing in the Bahamas for his birthday, tries some barracuda for dinner. Hours later, he collapses on the dance floor with crippling stomach pains. A middle-aged woman returns to her doctor, after visiting two days earlier with a mild rash on the back of her hands. Now the rash has turned purple and has spread across her entire body in whiplike streaks. A young elephant trainer in a traveling circus, once head-butted by a rogue zebra, is suddenly beset with splitting headaches, as if someone were "slamming a door inside his head."In each of these cases, the path to diagnosis--and treatment--is winding, sometimes frustratingly unclear. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck. Intricate, gripping, and full of twists and turns, Diagnosis puts readers in the doctor's place. It lets them see what doctors see, feel the uncertainty they feel--and experience the thrill when the puzzle is finally solved.

    Enjoy a journey through the eyes of a geek working at one of the most important companies in the world as he walks you through events both large and small. Just don't get caught in the Redmond reality distortion field! What others are saying about "A Microsoft Life": "Any self-respecting geek needs to read this book. Stepto provides an enjoyable and entertaining insight of life inside Microsoft." - Larry "Major Nelson" Hryb, Director of Programming for Xbox LIVE "Anyone who lived through the adolescent years of the computer revolution will alternate between laughing and crying (from laughing) at these great stories from inside the monolith. - Ken Denmead, NYT Bestselling Author, and editor of Geekdad.com

    In Talking as Fast as I Can, Lauren Graham hits pause for a moment and looks back on her life, sharing laugh-out-loud stories about growing up, starting out as an actress, and, years later, sitting in her trailer on the Parenthood set and asking herself, “Did you, um, make it?” She opens up about the challenges of being single in Hollywood (“Strangers were worried about me; that’s how long I was single!”), the time she was asked to audition her butt for a role, and her experience being a judge on Project Runway (“It’s like I had a fashion-induced blackout”). In “What It Was Like, Part One,” Graham sits down for an epic Gilmore Girls marathon and reflects on being cast as the fast-talking Lorelai Gilmore. The essay “What It Was Like, Part Two” reveals how it felt to pick up the role again nine years later, and what doing so has meant to her. Some more things you will learn about Lauren: She once tried to go vegan just to bond with Ellen DeGeneres, she’s aware that meeting guys at awards shows has its pitfalls (“If you’re meeting someone for the first time after three hours of hair, makeup, and styling, you’ve already set the bar too high”), and she’s a card-carrying REI shopper (“My bungee cords now earn points!”). Including photos and excerpts from the diary Graham kept during the filming of the recent Gilmore Girls: A Year in the Life, this book is like a cozy night in, catching up with your best friend, laughing and swapping stories, and—of course—talking as fast as you can.

    Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?In a swift and breathtaking narrative, Cahalan tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that nearly didn’t happen.

    Chelsea Handler, 1.5 oz. Nora Ephron, finish with a twist of Tina Fey, and you get Ali in Wonderland, the uproarious, revealing, and heartfelt memoir from acclaimed actress and comedian Ali Wentworth. Whether spilling secrets about her quintessentially WASPy upbringing (and her delicious rebellion against it), reminiscing about her Seinfeld “Schmoopie” days and her appearances on The Oprah Winfrey Show, The View, and The Tonight Show with Jay Leno, or baring the details of starting a family alongside husband George Stephanopoulos, one thing is for sure—Ali has the unsurpassable humor and warmth of a born storyteller with a story to tell: the quirky, flavorful, surprising, and sometimes scandalous Ali in Wonderland.“Ali Wentworth is funny and warm and crazy all at once. Like Barbara Eden. But on something. Like crystal meth.” —Alec Baldwin

    Staff nursing in a ward where she's challenged by an inventory driven ward sister, she reckons it's time to swap such trivialities for life as a district nurse.Independent thinking is one thing, but Jane's about to find that the drama on district can demand instant reaction; and without hospital back up, she's usually the one having to provide it. She meets a rich cast of patients all determined to follow their own individual star, and goes to Edinburgh where Queen Victoria's Jubilee Institute's nurse training is considered the cr me de la cr me of the district nursing world.Call Me Sister recalls Jane's challenging and often hilarious route to realizing her own particular dream.

    What they don’t know is her trailblazing career was a happy accident. In this funny and intimate memoir, Penny takes us from the stage of The Jackie Gleason Show in 1955 to Hollywood’s star-studded sets, offering up some hilarious detours along the way.My Mother Was Nuts is an intimate backstage pass to Penny’s personal life, her breakout role on The Odd Couple, her exploits with Cindy Williams and John Belushi, and her travels across Europe with Art Garfunkel on the back of a motorcycle. We see Penny get married. And divorced. And married again (the second time to Rob Reiner). We meet a young Carrie Fisher, whose close friendship with Penny has spanned decades. And we see Penny at work with Tom Hanks, Mark Wahlberg, Whoopi Goldberg, Robert De Niro, and Whitney Houston.Throughout it all, from her childhood spent tap dancing in the Bronx, to her rise as the star of Laverne & Shirley, Penny lived by simple rules: “try hard, help your friends, don’t get too crazy, and have fun.” With humor and heart, My Mother Was Nuts reveals there’s no one else quite like Penny Marshall.

    Difficulty breathing. Overwhelming dread. Andrea Petersen was first diagnosed with an anxiety disorder at the age of twenty, but she later realized that she had been experiencing panic attacks since childhood. With time her symptoms multiplied. She agonized over every odd physical sensation. She developed fears of driving on highways, going to movie theaters, even licking envelopes. Although having a name for her condition was an enormous relief, it was only the beginning of a journey to understand and master it—one that took her from psychiatrists’ offices to yoga retreats to the Appalachian Trail. Woven into Petersen’s personal story is a fascinating look at the biology of anxiety and the groundbreaking research that might point the way to new treatments. She compares psychoactive drugs to non-drug treatments, including biofeedback and exposure therapy. And she explores the role that genetics and the environment play in mental illness, visiting top neuroscientists and tracing her family history—from her grandmother, who, plagued by paranoia, once tried to burn down her own house, to her young daughter, in whom Petersen sees shades of herself. Brave and empowering, this is essential reading for anyone who knows what it means to live on edge.

    Overnight, these women were transformed from military spouses into American royalty. They had tea with Jackie Kennedy, appeared on the cover of Life magazine, and quickly grew into fashion icons.Annie Glenn, with her picture-perfect marriage, was the envy of the other wives; JFK made it clear that platinum-blonde Rene Carpenter was his favorite; and licensed pilot Trudy Cooper arrived with a secret that needed to stay hidden from NASA. Together with the other wives they formed the Astronaut Wives Club, providing one another with support and friendship, coffee and cocktails.As their celebrity rose-and as divorce and tragedy began to touch their lives-the wives continued to rally together, forming bonds that would withstand the test of time, and they have stayed friends for over half a century. THE ASTRONAUT WIVES CLUB tells the story of the women who stood beside some of the biggest heroes in American history.

    Armstrong writes about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. This book recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.

    Abby shows us by example how to overcome problems and live a happier, braver life." —Sheryl Sandberg, Facebook COO, New York Times Bestselling author of Lean In “This is the best memoir I’ve read by an athlete since Andre Agassi’s Open. I could not put it down, and you will not want it to end.”  —Adam Grant, Wharton professor and New York Times bestselling author of Originals and Give and TakeAbby Wambach has always pushed the limits of what is possible. At age seven she was put on the boys’ soccer team. At age thirty-five she would become the highest goal scorer—male or female—in the history of soccer, capturing the nation’s heart with her team’s 2015 World Cup Championship. Called an inspiration and “badass” by President Obama, Abby has become a fierce advocate for women’s rights and equal opportunity, pushing to translate the success of her team to the real world.As she reveals in this searching memoir, Abby’s professional success often masked her inner struggle to reconcile the various parts of herself: ferocious competitor, daughter, leader, wife. With stunning candor, Abby shares her inspiring and often brutal journey from girl in Rochester, New York, to world-class athlete. Far more than a sports memoir, Forward is gripping tale of resilience and redemption—and a reminder that heroism is, above all, about embracing life’s challenges with fearlessness and heart.

    In this book, John Prine curates a selection of his best loved songs. Included are lyrics, guitar chords, commentary from John and over 100 photographs - may never before published - from his personal collection. John Prine has written songs that have become central to the American musical heritage. This former Maywood, Illinois mailman came to prominence with his debut record, 'John Prine' in 1971, which includes classics like, "Angel from Montgomery," "Sam Stone," "Paradise," and "Hello in There." His lyrics speak to the everyday experience of ordinary people, with a simple honesty and an extraordinary ability to connect with the heart.

    From that day forward his life became a hell of uncontrollable tics, urges, and involuntary utterances. Eventually he is diagnosed with Tourette's Syndrome and Obsessive Compulsive disorder, and Cory embarks on an excruciating journey from specialist to specialist, enduring countless combinations of medications in wildly varying doses. Soon it becomes unclear what tics are symptoms of his disease and what are side effects of the drugs. The only certainty is that it kept getting worse. Despite his lack of control, Cory is aware of every embarrassing movement, and sensitive to every person's reaction to his often aggravating presence. Simply put: Cory Friedman's life is a living hell.Against Medical Advice is the true story of one family's decades-long battle for survival in the face of extraordinary difficulties and a rigid medical establishment.

    Then imagine that someone suddenly switches the lights on.It has long been assumed that people living with autism are born with the diminished ability to read the emotions of others, even as they feel emotion deeply. But what if we’ve been wrong all this time? What if that “missing” emotional insight was there all along, locked away and inaccessible in the mind?   In 2007 John Elder Robison wrote the international bestseller Look Me in the Eye, a memoir about growing up with Asperger’s syndrome. Amid the blaze of publicity that followed, he received a unique invitation: Would John like to take part in a study led by one of the world’s foremost neuroscientists, who would use an experimental new brain therapy known as TMS, or transcranial magnetic stimulation, in an effort to understand and then address the issues at the heart of autism? Switched On is the extraordinary story of what happened next.   Having spent forty years as a social outcast, misreading others’ emotions or missing them completely, John is suddenly able to sense a powerful range of feelings in other people. However, this newfound insight brings unforeseen problems and serious questions. As the emotional ground shifts beneath his feet, John struggles with the very real possibility that choosing to diminish his disability might also mean sacrificing his unique gifts and even some of his closest relationships. Switched On is a real-life Flowers for Algernon, a fascinating and intimate window into what it means to be neurologically different, and what happens when the world as you know it is upended overnight.

    His memoir is a reflection on his diverse collection of experiences, both hilarious and heartbreaking.Short takes us through his career, from his early years with Second City Toronto and "Saturday Night Live" to his movie, stage, and television stardom. He recalls how he developed some of his enduring characters manic man-child Ed Grimley, elderly Tin Pan Alley songmith Irving Cohen, slimy lawyer Nathan Thurm, and the blubbery and bizarrely insensitive Jiminy Glick. Here, too, are his movie and television appearances, from the classic " Three Amigos!" to his Emmy-nominated role in "Damages," as well as his stage productions, including his Tony Award winning performance in "Little Me." Throughout, such friends and luminaries as Steve Martin, Tom Hanks, John Candy, Gilda Radner, Lorne Michaels, Nora Ephron, Frank Sinatra, and others share the spotlight.This deeply private man brings us into the circle of his family life, from raising his children to the legendary parties he and his wife hosted in their Los Angeles home. He recounts the pain of losing a brother and both parents by the time he was twenty and of the devastating death of Nancy, his wife of thirty years, in 2010. Despite the hardships, Short s life has been full of laughter, and he remains perennially upbeat. In this wise and entertaining memoir, he shares his irrepressible joy."