But philosopher and cognitive scientist Andy Clark sees it differently. Cyborgs, he writes, are not something to be feared--we already are cyborgs. In Natural-Born Cyborgs, Clark argues that what makes humans so different from other species is our capacity to fully incorporate tools and supporting cultural practices into our existence. Technology as simple as writing on a sketchpad, as familiar as Google or a cellular phone, and as potentially revolutionary as mind-extending neural implants--all exploit our brains' astonishingly plastic nature. Our minds are primed to seek out and incorporate non-biological resources, so that we actually think and feel through our best technologies. Drawing on his expertise in cognitive science, Clark demonstrates that our sense of self and of physical presence can be expanded to a remarkable extent, placing the long-existing telephone and the emerging technology of telepresence on the same continuum. He explores ways in which we have adapted our lives to make use of technology (the measurement of time, for example, has wrought enormous changes in human existence), as well as ways in which increasingly fluid technologies can adapt to individual users during normal use. Bio-technological unions, Clark argues, are evolving with a speed never seen before in history. As we enter an age of wearable computers, sensory augmentation, wireless devices, intelligent environments, thought-controlled prosthetics, and rapid-fire information search and retrieval, the line between the user and her tools grows thinner day by day. This double whammy of plastic brains and increasingly responsive and well-fitted tools creates an unprecedented opportunity for ever-closer kinds of human-machine merger, he writes, arguing that such a merger is entirely natural. A stunning new look at the human brain and the human self, Natural Born Cyborgs reveals how our technology is indeed inseparable from who we are and how we think.

    And we all have stories.The bite attacks that Pamela Nagami, M.D., has chosen to write about in Bitten take place in big cities, small towns, and remote villages around the world and throughout history, locales as familiar as New York or Hollywood, or exotic as Africa, the Middle East, or Indonesia. They include a six-year-old girl who descended into weeks of extreme lassitude from a tick bite; a diabetic in the West Indies who awoke to find a rat eating two of his toes; a California man who developed "flesh-eating strep" following a penile bite; and more.With reports from medical journals, case histories, colleagues, and her own twenty-five-year career as a practicing physician and infectious diseases specialist, Pamela Nagami offers readers intrigued by infection, disease, and mesmerized by creatures in the wild a compulsively readable narrative that is entertaining, sometimes disturbing, and always engrossing.

    With a new preface about the significance of the discovery of the Higgs particle, A Universe from Nothing uses Krauss’s characteristic wry humor and wonderfully clear explanations to take us back to the beginning of the beginning, presenting the most recent evidence for how our universe evolved—and the implications for how it’s going to end. Provocative, challenging, and delightfully readable, this is a game-changing look at the most basic underpinning of existence and a powerful antidote to outmoded philosophical, religious, and scientific thinking.

    We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    But new research from neuroscientists and psychologists suggests that, in fact, the brain reorganizes, improves in important functions, and even helps us adopt a more optimistic outlook in middle age. Growth of white matter and brain connectors allow us to recognize patterns faster, make better judgments, and find unique solutions to problems. Scientists call these traits cognitive expertise and they reach their highest levels in middle age. In her impeccably researched book, science writer Barbara Strauch explores the latest findings that demonstrate, through the use of technology such as brain scans, that the middle-aged brain is more flexible and more capable than previously thought. For the first time, long-term studies show that our view of middle age has been misleading and incomplete. By detailing exactly the normal, healthy brain functions over time, Strauch also explains how its optimal processes can be maintained. Part scientific survey, part how-to guide, "The Secret Life of the Grown-Up Brain" is a fascinating glimpse at our surprisingly talented middle-aged minds."

    But AIDS is just one of the many emerging viruses for which we have, as yet, no cure. Even the old plagues – TB, cholera, bubonic plague – are making a comeback, resistant now to our drugs.Frank Ryan, a leading authority on disease, describes the groundbreaking research of the world’s leading experts in the field to show both where these viruses come from and why they prove to be so lethal, and advances a radical new biological theory for the origins and behaviour of plague viruses. Full of vivid despatches from the front line of research and medicine, 'Virus X' is terrifying and essential reading for anyone interested in the effects of plague viruses on human evolution.“Extremely well written…Frank Ryan has the page-turning and spine-chilling ability of a good novelist”MATT RIDLEY, 'Sunday Telegraph'“Compelling and frightening…the plot could not be bettered”MICHAEL SMITH, 'Scotsman'“Ryan is very good at making technical matters comprehensible to the lay reader but more impressive still is the way he conveys the intellectual excitement and elation of scientific discovery”ANTHONY DANIELS, 'Literary Review'“Ryan takes us through the drama of discovery and challenges the notion that certain questions are too appalling to contemplate”DAVID BRADLEY, 'New Scientist'“Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives…very readable and disturbing”JOHN R.G. TURNER, 'New York Times'

    Wilczek’s groundbreaking work in quantum physics was inspired by his intuition to look for a deeper order of beauty in nature. In fact, every major advance in his career came from this intuition: to assume that the universe embodies beautiful forms, forms whose hallmarks are symmetry—harmony, balance, proportion—and economy. There are other meanings of “beauty,” but this is the deep logic of the universe—and it is no accident that it is also at the heart of what we find aesthetically pleasing and inspiring.Wilczek is hardly alone among great scientists in charting his course using beauty as his compass. As he reveals in A Beautiful Question, this has been the heart of scientific pursuit from Pythagoras, the ancient Greek who was the first to argue that “all things are number,” to Galileo, Newton, Maxwell, Einstein, and into the deep waters of twentiethcentury physics. Though the ancients weren’t right about everything, their ardent belief in the music of the spheres has proved true down to the quantum level. Indeed, Wilczek explores just how intertwined our ideas about beauty and art are with our scientific understanding of the cosmos.Wilczek brings us right to the edge of knowledge today, where the core insights of even the craziest quantum ideas apply principles we all understand. The equations for atoms and light are almost literally the same equations that govern musical instruments and sound; the subatomic particles that are responsible for most of our mass are determined by simple geometric symmetries. The universe itself, suggests Wilczek, seems to want to embody beautiful and elegant forms. Perhaps this force is the pure elegance of numbers, perhaps the work of a higher being, or somewhere between. Either way, we don’t depart from the infinite and infinitesimal after all; we’re profoundly connected to them, and we connect them. When we find that our sense of beauty is realized in the physical world, we are discovering something about the world, but also something about ourselves.Gorgeously illustrated, A Beautiful Question is a mind-shifting book that braids the age-old quest for beauty and the age-old quest for truth into a thrilling synthesis. It is a dazzling and important work from one of our best thinkers, whose humor and infectious sense of wonder animate every page. Yes: The world is a work of art, and its deepest truths are ones we already feel, as if they were somehow written in our souls.

    Its starting point is the annual Turing Test, which pits artificial intelligence programs against people to determine if computers can “think.”Named for computer pioneer Alan Turing, the Tur­ing Test convenes a panel of judges who pose questions—ranging anywhere from celebrity gossip to moral conundrums—to hidden contestants in an attempt to discern which is human and which is a computer. The machine that most often fools the panel wins the Most Human Computer Award. But there is also a prize, bizarre and intriguing, for the Most Human Human.In 2008, the top AI program came short of passing the Turing Test by just one astonishing vote. In 2009, Brian Christian was chosen to participate, and he set out to make sure Homo sapiens would prevail.The author’s quest to be deemed more human than a com­puter opens a window onto our own nature. Interweaving modern phenomena like customer service “chatbots” and men using programmed dialogue to pick up women in bars with insights from fields as diverse as chess, psychiatry, and the law, Brian Christian examines the philosophical, bio­logical, and moral issues raised by the Turing Test.One central definition of human has been “a being that could reason.” If computers can reason, what does that mean for the special place we reserve for humanity?

    People in this middle place have sustained traumatic brain injuries or are the victims of stroke or degenerative diseases, such as Alzheimer’s and Parkinson’s. Many are oblivious to the outside world, and their doctors believe they are incapable of thought. But a sizeable number are experiencing something different: intact minds adrift deep within damaged brains and bodies. Following Owen’s journey of exciting medical discovery, Into the Gray Zone asks some tough and terrifying questions, such as: What is life like for these patients? What can their families and friends do to help them? What are the ethical implications for religious organizations, politicians, the Right to Die movement, and even insurers? And perhaps most intriguing of all: in defining what a life worth living is, are we too concerned with the physical and not giving enough emphasis to the power of thought? What, truly, defines a satisfying life?

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    I was mentally and physically broken. So fractured, I hadn't eaten properly or slept well, or even changed my expression for months. I sat in a cubicle, behind paper-thin curtains, listening to the rest of the hospital happen around me, and I shook with the effort of not crying. I was an inch away from defeat, from the acceptance of a failure I assumed would be inevitable, but I knew I had to carry on. I had to somehow walk through it.Because I wasn't the patient. I was the doctor."A frank account of mental health from both sides of the doctor-patient divide, from the bestselling author of The Trouble with Goats and Sheep and Three Things About Elsie, based on her own experience as a doctor working on a psychiatric ward.

    Would you want to know? Taking a uniquely intimate and cheeky approach to the personal genomics revolution, internationally acclaimed science writer Lone Frank swabs up her genetic code to explore who any of us are in the days when a catalogue of your full six billion DNA building blocks is available for $10,000 and the local Walgreens offers genetic screening tests to anyone. She challenges the august Nobel Prize winners and the hyperactive business mavericks who are pushing to map and decipher every fetus’s genome within the next decade. She tests the potential to detect diseases early, as well as our capacity to develop chronic anxieties when our DNA is seen as a death sentence. She ponders whether personality, including her own above-average irritability and non-conformity, can really be reduced to biochemistry. And she prods the psychologists who hope to uncover just how much or how little our environment will matter in the new genetic century — a quest made all the more gripping as Frank considers her family’s and her own struggles with depression. At turns compellingly candid and irreverently insightful, Frank provides the first truly personal account of the new science of consumer-led genomics — and to what extent our genes determine our destiny. Lone Frank is the author of The Neurotourist: Postcards from the Edge of Brain Science (ISBN 9781851687961). She holds a PhD in neurobiology and was previously a research scientist working in the biotechnology industry in the United States. An award-winning science journalist and TV documentary presenter, she has written for such publicationsn as Scientific American, Science, and Nature Biotechnology and is a frequent speaker at venues including Harvard Medical School, the Library of Congress, the Royal Society, and TED. Praise for The Neurotourist: “A fascinating exploration of the most intriguing brain experiments so far.” New Scientist “Riveting.” Rita Carter, author of Mapping the Mind

    These individuals all lost some part of what we think of as our self, but they then offer remarkable, sometimes heart-wrenching insights into what remains. One man cut off his own leg. Another became one with the universe.We are learning about the self at a level of detail that Descartes (“I think therefore I am”) could never have imagined. Recent research into Alzheimer’s illuminates how memory creates your narrative self by using the same part of your brain for your past as for your future. But wait, those afflicted with Cotard’s syndrome think they are already dead; in a way, they believe that “I think therefore I am not.” Who—or what—can say that? Neuroscience has identified specific regions of the brain that, when they misfire, can cause the self to move back and forth between the body and a doppelgänger, or to leave the body entirely. So where in the brain, or mind, or body, is the self actually located? As Ananthaswamy elegantly reports, neuroscientists themselves now see that the elusive sense of self is both everywhere and nowhere in the human brain.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.