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    The first small cities formed not only the cradle of civilization, but the spawning ground for the earliest viral epidemics, the first opportunity for viruses to find a home in the human herd. This is a story of fear and ignorance, as everything from demons and the wrath of the gods to minority groups have been blamed for epidemics from smallpox to yellow fever to AIDS. It is a story of grief and heartbreak, as hundreds of thousands, sometimes millions, are wiped out in a single year. And it is a story of great bravery and sacrifice, as doctors and nurses put themselves in harm's way to combat yellow fever in Memphis and Ebola in Zaire, and as researchers risk their own lives to test theories of vaccines and the transmission of disease. Now, in Viruses, Plagues, and History, Michael B. A. Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity.Oldstone focuses his tale on a few of the most famous viruses humanity has battled, beginning with some we have effectively defeated, such as smallpox, polio, and measles. Nearly 300 million people were killed by smallpox in this century alone -- more than were killed in all the wars of the twentieth century combined. The author presents a vivid account of the long campaign against the virus, the insightful work of Edward Jenner, who created the smallpox vaccine from cowpox virus in 1796, and the monumental efforts of D. A. Henderson and an army of W.H.O. health care workers to finally eradicate smallpox. The smallpox virus remains the only organism that we have deliberately pushed to complete extinction in the wild.Oldstone then describes the fascinating viruses that have captured headlines in more recent years: Ebola and other hemorrhagic fevers, which literally turn their victims' organs to a bloody pulp; the Hantavirus outbreaks in the southwestern United States and elsewhere; mad cow disease, a frightening illness made worse by government mishandling and secrecy; and, of course, AIDS, often called the plague of our time. And he tells us of the many scientists watching and waiting even now for the next great plague, monitoring influenza strains to see whether the deadly variant from 1918 -- a viral strain that killed over 20 million people in 1918-1919, more than twice the military and civilian casualties of the First World War -- will make a comeback.Viruses have enormous power. They have wiped out cities, brought down dynasties, and helped destroy civilizations. But, as Michael Oldstone reveals, scientific research has given us the power to tame many of these viruses as well. Viruses, Plagues, and History shows us the panorama of humanity's long-standing conflict with our unseen viral enemies, from our successes to our continuing struggles. Oldstone's book is a vivid history of a fascinating field, and a highly reliable dispatch from a worker on the frontiers of this ongoing campaign.

    Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic; the visionary scientist Gregory Pincus, who was dismissed by Harvard in the 1930s as a result of his experimentation with in vitro fertilization but who, after he was approached by Sanger and McCormick, grew obsessed with the idea of inventing a drug that could stop ovulation; and the telegenic John Rock, a Catholic doctor from Boston who battled his own church to become an enormously effective advocate in the effort to win public approval for the drug that would be marketed by Searle as Enovid.Spanning the years from Sanger’s heady Greenwich Village days in the early twentieth century to trial tests in Puerto Rico in the 1950s to the cusp of the sexual revolution in the 1960s, this is a grand story of radical feminist politics, scientific ingenuity, establishment opposition, and, ultimately, a sea change in social attitudes. Brilliantly researched and briskly written, The Birth of the Pill is gripping social, cultural, and scientific history.

    In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    The implications of their discoveries form tomorrow's headlines, yet Angier writes about the scientists themselves and not merely theri successes. 4-page photo insert.

    His claim that “harnessing the forces of nature was the only worthwhile scientific endeavor" both impressed and enraged the scientific community. Eventually, his peers could no longer dismiss his eccentricities and began to view him as a crackpot — a potentially dangerous one. Although Tesla’s work was a major factor in the success of the second Industrial Revolution, he died alone, impoverished, and largely shunned by the scientific community that once hailed him a genius. Beset by visions, without a wife or children, Nikola Tesla’s brilliant mind changed the world, even though at the time of his death he passed unnoticed into obscurity. Some of the topics covered in this book include: Childhood Education and Early Career Patents and Politics The Eccentric Genius Tesla’s Coil and the Niagara Contract Influential Friends and the Lure of Flight The Wardenclyffe Tower 1914 and Beyond And much more! Scroll to the top and select the "BUY NOW" button for instant download

    David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    This book engaged some of the hardest questions in the evolution debate, and it showed the ever-cautious Darwin at his boldest. If Darwin had one goal with Expression , it was to demonstrate the power of his theories for explaining the origin of our most cherished human qualities: morality and intellect. As Darwin explained, "He who admits, on general grounds, that the structure and habits of all animals have been gradually evolved, will look at the whole subject of Expression in a new and interesting light." Table Of Contents: Table of contents The Expression of the Emotions in Man and Animals Acknowledgements Chronology Introduction Further Reading Note on the Text The Expression of the Emotions in Man and Animals Appendix 1: Translation of French quotations Appendix 2: Darwin's 'Queries About Expression' Appendix 3: List of supplementary images Index

    

    Only ten of them?about 3 percent?have been women. Why? In this updated version of Nobel Prize Women in Science, Sharon Bertsch McGrayne explores the reasons for this astonishing disparity by examining the lives and achievements of fifteen women scientists who either won a Nobel Prize or played a crucial role in a Nobel Prize - winning project. The book reveals the relentless discrimination these women faced both as students and as researchers. Their success was due to the fact that they were passionately in love with science.The book begins with Marie Curie, the first woman to win the Nobel Prize in physics. Readers are then introduced to Christiane Nusslein-Volhard, Emmy Noether, Lise Meitner, Barbara McClintock, Chien-Shiung Wu, and Rosalind Franklin. These and other remarkable women portrayed here struggled against gender discrimination, raised families, and became political and religious leaders. They were mountain climbers, musicians, seamstresses, and gourmet cooks. Above all, they were strong, joyful women in love with discovery.Nobel Prize Women in Science is a startling and revealing look into the history of science and the critical and inspiring role that women have played in the drama of scientific progress.

    The book is an original contribution to the intertwined narratives of humanity and its planet.Drawing on the findings of geology, anthropology, archaeology and earth science, Colin Tudge discusses in detail and intertwines histories of the planet Earth and the evolution of humankind.

    Before this explosive growth into the modern age took place, an all-but-forgotten genius strove for forty years to win acceptance for the atomic theory of matter and an altogether new way of doing physics. Ludwig Boltz-mann battled with philosophers, the scientific establishment, and his own potent demons. His victory led the way to the greatest scientific achievements of the twentieth century. Now acclaimed science writer David Lindley portrays the dramatic story of Boltzmann and his embrace of the atom, while providing a window on the civilized world that gave birth to our scientific era. Boltzmann emerges as an endearingly quixotic character, passionately inspired by Beethoven, who muddled through the practical matters of life in a European gilded age. Boltzmann's story reaches from fin de siecle Vienna, across Germany and Britain, to America. As the Habsburg Empire was crumbling, Germany's intellectual might was growing; Edinburgh in Scotland was one of the most intellectually fertile places on earth; and, in America, brilliant independent minds were beginning to draw on the best ideas of the bureaucratized old world.Boltzmann's nemesis in the field of theoretical physics at home in Austria was Ernst Mach, noted today in the term Mach I, the speed of sound. Mach believed physics should address only that which could be directly observed. How could we know that frisky atoms jiggling about corresponded to heat if we couldn't see them? Why should we bother with theories that only told us what would probably happen, rather than making an absolute prediction? Mach and Boltzmann both believed in the power of science, but their approaches to physics could not have been more opposed. Boltzmann sought to explain the real world, and cast aside any philosophical criteria. Mach, along with many nineteenth-century scientists, wanted to construct an empirical edifice of absolute truths that obeyed strict philosophical rules. Boltzmann did not get on well with authority in any form, and he did his best work at arm's length from it. When at the end of his career he engaged with the philosophical authorities in the Viennese academy, the results were personally disastrous and tragic. Yet Boltzmann's enduring legacy lives on in the new physics and technology of our wired world.Lindley's elegant telling of this tale combines the detailed breadth of the best history, the beauty of theoretical physics, and the psychological insight belonging to the finest of novels.

    For five years in his mid-twenties, he sailed on the BEAGLE around the world, exploring jungles, climbing mountains, trekking across deserts. With every new landfall, he had new adventures: he rode through bandit country, was thrown into jail by revolutionaries, took part in an armed raid with marines, survived two earthquakes, hunted and fished. He suffered the terrible cold and rain of Tierra del Fuego, the merciless heat of the Australian outback and the inner pangs of heartbreak. He also made the discoveries that finally led him to formulate his theory of Natural Selection as the driving force of evolution. The five-year voyage of the BEAGLE was the basis for all Darwin's later work; but it also turned him from a friendly idler into the greatest scientist of his century. Kevin Jackson is a writer, broadcaster and film-maker. His most recent book is Constellation of Genius: 1922 and All That Jazz (Farrar Strauss Giroux, 2013). He lives in Cambridge, England.

    It hold the remains of an ancient sea where dozens of strange creatures lived—a forgotten corner of evolution preserved in awesome detail. In this book Stephen Jay Gould explores what the Burgess Shale tells us about evolution and the nature of history.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.