Indeed, complementary and alternative medicine is embraced by a broad spectrum of society, from ordinary people, to scientists and physicians, to celebrities such as Prince Charles andOprah Winfrey. In the tradition of Michael Shermers Why People Believe Weird Things and Robert Parks's Voodoo Science, Barker Bausell provides an engaging look at the scientific evidence for complementary and alternative medicine (CAM) and at the logical, psychological, and physiological pitfalls that leadotherwise intelligent people--including researchers, physicians, and therapists--to endorse these cures. The books ultimate goal is to reveal not whether these therapies work--as Bausell explains, most do work, although weakly and temporarily--but whether they work for the reasons their proponentsbelieve. Indeed, as Bausell reveals, it is the placebo effect that accounts for most of the positive results. He explores this remarkable phenomenon--the biological and chemical evidence for the placebo effect, how it works in the body, and why research on any therapy that does not factor in theplacebo effect will inevitably produce false results. By contrast, as Bausell shows in an impressive survey of research from high-quality scientific journals and systematic reviews, studies employing credible placebo controls do not indicate positive effects for CAM therapies over and above thoseattributable to random chance. Here is not only an entertaining critique of the strangely zealous world of CAM belief and practice, but it also a first-rate introduction to how to correctly interpret scientific research of any sort. Readers will come away with a solid understanding of good vs. bad research practice and ahealthy skepticism of claims about the latest miracle cure, be it St. John's Wort for depression or acupuncture for chronic pain.

    By the time he died, his fortune amounted to nearly two percent of European GDP. Not even John D. Rockefeller had that kind of wealth. Most people become rich by spotting opportunities, pioneering new technologies, or besting opponents in negotiations. Fugger did all that, but he had an extra quality that allowed him to rise even higher: nerve. In an era when kings had unlimited power, Fugger had the nerve to stare down heads of state and ask them to pay back their loans--with interest. It was this coolness and self-assurance, along with his inexhaustible ambition, that made him not only the richest man ever, but a force of history as well. Before Fugger came along it was illegal under church law to charge interest on loans, but he got the Pope to change that. He also helped trigger the Reformation and likely funded Magellan's circumnavigation of the globe. His creation of a news service, which gave him an information edge over his rivals and customers, earned Fugger a footnote in the history of journalism. And he took Austria's Habsburg family from being second-tier sovereigns to rulers of the first empire where the sun never set.The ultimate untold story, The Richest Man Who Ever Lived is more than a tale about the richest and most influential businessman of all time. It is a story about palace intrigue, knights in battle, family tragedy and triumph, and a violent clash between the 1 percent and everybody else. To understand our financial system and how we got it, it pays to understand Jacob Fugger.

    The Cell: a Molecular Approach meets this challenge by providing students with not only the current information, but also with an introduction to the experimental nature of contemporary research. Designed for use in introductory cell biology courses, The Cell presents current, comprehensive science in a readable and cohesive text that students can master in the course of one semester. The new third edition of The Cell retains the organization, themes, and special features of earlier editions, but is updated to reflect scientific advances since publication of the second edition, including progress in genome sequencing, advances in understanding transcriptional regulation and mRNA processing, use of DNA microarrays in global studies of gene expression and cancer diagnostics, advances in nuclear transport and protein trafficking, progress in understanding the regulation of programmed cell death, potential medical applications of embryonic cells, and development of oncogene-targeted treatments. Key Experimental boxes in each chapter describe seminal experiments in modern cell biology, showing the detail and background to give students a sense of doing science. Molecular Medicine boxes relate basic science to clinical practice or potential and show the excitement of molecular discovery and solutions to disease. Chapter summaries are organized in outline form corresponding to the major sections and subsections of each chapter. This section-by-section format is coupled with a list of the key terms introduced in eachsection, providing a succinct but comprehensive review of the material. The full-color art program is both pedagogically and scientifically outstanding. In addition, each chapter includes a brief chapter outline, boldfaced key terms (also defined in the glossary), and many new chapter-end questions with answers in the back of the book. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. The book can be bundled for purchase with a special edition of Molecules, Cells, and Genes, a CD-ROM keyed to the textbook and combining the essential features of a Study Guide and Problems book.

    She loved the ocean and wrote three books about its mysteries, including the international bestseller The Sea Around Us. But it was with her fourth book, Silent Spring, that this unassuming biologist transformed our relationship with the natural world.Rachel Carson began work on Silent Spring in the late 1950s, when a dizzying array of synthetic pesticides had come into use. Leading this chemical onslaught was the insecticide DDT, whose inventor had won a Nobel Prize for its discovery. Effective against crop pests as well as insects that transmitted human diseases such as typhus and malaria, DDT had at first appeared safe. But as its use expanded, alarming reports surfaced of collateral damage to fish, birds, and other wildlife. Silent Spring was a chilling indictment of DDT and its effects, which were lasting, widespread, and lethal.Published in 1962, Silent Spring shocked the public and forced the government to take action-despite a withering attack on Carson from the chemicals industry. The book awakened the world to the heedless contamination of the environment and eventually led to the establishment of the EPA and to the banning of DDT and a host of related pesticides. By drawing frightening parallels between dangerous chemicals and the then-pervasive fallout from nuclear testing, Carson opened a fault line between the gentle ideal of conservation and the more urgent new concept of environmentalism.Elegantly written and meticulously researched, On a Farther Shore reveals a shy yet passionate woman more at home in the natural world than in the literary one that embraced her. William Souder also writes sensitively of Carson's romantic friendship with Dorothy Freeman, and of her death from cancer in 1964. This extraordinary new biography captures the essence of one of the great reformers of the twentieth century.A New York Times Notable Book of 2012“A suspenseful tale of the literary life…utterly inspiring.” —San Francisco Chronicle“Captivating…Souder writes vividly and with great empathy for his subject and her cause.” —New York Times Book Review“A delightful, fascinating, engrossing read about some of the most important insights of modern science. You’ll find yourself thinking about Carson whenever you take a walk in the woods.” —Slate.com

    KEY TOPICS: A Preview of the Cell, The Chemistry of the Cell, The Macromolecules of the Cell, Cells and Organelles, Bioenergetics: The Flow of Energy in the Cell, Enzymes: The Catalysts of Life, Membranes: Their Structure, Function, and Chemistry, Transport Across Membranes: Overcoming the Permeability Barrier, Chemotrophic Energy Metabolism: Glycolysis and Fermentation, Chemotrophic Energy Metabolism: Aerobic Respiration, Phototrophic Energy Metabolism: Photosynthesis, The Endomembrane System and Peroxisomes, Signal Transduction Mechanisms: I. Electrical and Synaptic Signaling in Neurons, Signal Transduction Mechanisms: II. Messengers and Receptors, Cytoskeletal Systems, Cellular Movement: Motility and Contractility, Beyond the Cell: Cell Adhesion, Cell Junctions, and Extracellular Structures, The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus, The Cell Cycle, DNA Replication, and Mitosis, Sexual Reproduction, Meiosis, and Genetic Recombination, Gene Expression: I. The Genetic Code and Transcription, Gene Expression: II. Protein Synthesis and Sorting, The Regulation of Gene Expression, Cancer Cells, Principles and Techniques of Microscopy. MARKET: For all readers interested in molecular biology.

    A portrait of one of America's most influential comedians analyzes the complex, sometimes disturbing world of Jerry Lewis, from his rise to fame and his philanthropic work to the dark side of his career and personal life.

    He argued that animals have "a taste for the beautiful" that drives their potential mates to evolve features that make them more sexually attractive and reproductively successful. But if Darwin explained why sexual beauty evolved in animals, he struggled to understand how. In A Taste for the Beautiful, Michael Ryan, one of the world's leading authorities on animal behavior, tells the remarkable story of how he and other scientists have taken up where Darwin left off and transformed our understanding of sexual selection, shedding new light on human behavior in the process.Drawing on cutting-edge work in neuroscience and evolutionary biology, as well as his own important studies of the tiny T�ngara frog deep in the jungles of Panama, Ryan explores the key questions: Why do animals perceive certain traits as beautiful and others not? Do animals have an inherent sexual aesthetic and, if so, where is it rooted? Ryan argues that the answers to these questions lie in the brain--particularly of females, who act as biological puppeteers, spurring the development of beautiful traits in males. This theory of how sexual beauty evolves explains its astonishing diversity and provides new insights about the degree to which our own perception of beauty resembles that of other animals.Vividly written and filled with fascinating stories, A Taste for the Beautiful will change how you think about beauty and attraction.

    Following a bidding war between Justin Timberlake and Usher, the fifteen-year-old singing sensation has had four singles hit the Top 40—before his first record was even released. With that kind of popularity, it’s no wonder that Harlee Harte, author of the “I ♥” series, is on the case! Harlee is the celebrity columnist for Hollywoodland High’s student newspaper. Accompanied by her fun, fashion-forward and fabulous friends, Harlee’s “all-access” press credentials let her get up close and personal with Justin backstage, on the road, and even at major awards ceremonies. Not just a paste-up of Justin Bieber facts, Harlee’s columns are full of puzzles, quizzes, and games that bring her devoted readers closer to this top tween celebrity than ever before. Follow Harlee on Justin’s trail as she tries to juggle the ups and downs, twists and turns of her everyday teenage life—school, boys, girlfriends, parents, and, of course, staying connected with all things Bieber.

    Includes a 30-page bibliographical essay, numerous illustrations, and a full-color pictorial biography of the composer.

    No other animal carries in its brain so many memories of such complexity nor so regularly revisits those memories for happiness, safety, and to accomplish complex tasks. Human civilization continues because we are able to pass along memories from one person to another, from one generation to the next. The Guardian of All Things is scientific history that takes us on a 10,000 year old journey replete with incredible ideas, inventions, and transformations. From cave drawings to oral histories to libraries to the internet, The Guardian of All Things is the history of how humans have relentlessly pursued new ways to preserve and manage memory, both within the human brain and is a series of inventions external to it. Michael Malone looks at the story of memory, both human and mechanical, and the historic turning points in that story that not only changed our relationship to memory, but also changed us as human beings. Full of anecdotes, history, and advances of civilization and technology, The Guardian of All Things is a lively, sweeping, and epic journey along a trajectory of history no other book has ever described, one that will appeal to the curious as well as the specialist.

    

    This is a book that became an instant cult classic.

    James Cleaves II seek to answer the most crucial question in science: How did life begin? They trace the trials and triumphs of the iconoclastic scientists who have sought to solve the mystery, from Darwin’s theory of evolution to Crick and Watson’s unveiling of DNA. This fascinating exploration not only examines the origin-of-life question, but also interrogates the very nature of scientific discovery and objectivity.

    Random genetic mutation, long believed to be the main source of variation, is only a marginal factor. As the authors demonstrate in this book, the more important source of speciation, by far, is the acquisition of new genomes by symbiotic merger. The result of thirty years of delving into a vast, mostly arcane literature, this is the first book to go beyond -- and reveal the severe limitations of -- the "Modern Synthesis" that has dominated evolutionary biology for almost three generations. Lynn Margulis, whom E. O. Wilson called "one of the most successful synthetic thinkers in modern biology," and her co-author Dorion Sagan have written a comprehensive and scientifically supported presentation of a theory that directly challenges the assumptions we hold about the variety of the living world.

    The discovery initiated Gessen into a club of sorts: the small (but exponentially expanding) group of people in possession of a new and different way of knowing themselves through what is inscribed in the strands of their DNA. As she wrestled with a wrenching personal decision—what to do with such knowledge—Gessen explored the landscape of this brave new world, speaking with others like her and with experts including medical researchers, historians, and religious thinkers. Blood Matters is a much-needed field guide to this unfamiliar and unsettling territory. It explores the way genetic information is shaping the decisions we make, not only about our physical and emotional health but about whom we marry, the children we bear, even the personality traits we long to have. And it helps us come to terms with the radical transformation that genetic information is engineering in our most basic sense of who we are and what we might become.