The first and only true textbook written by professors who teach the undergraduate course, it presents the most current concepts in an experimental context with clinical advances highlighted in boxes, supported by the kind of helpful pedagogical tools that other books do not provide.

    Turn to any page, and you'll find essential point-of-care guidance on all the major conditions seen in clinical medicine. Completely updated to reflect all the major advances and new clinical developments, the new edition of the Manual is the most indispensable yet. It continues to focus on diagnosis and therapy with an emphasis on patient care and offers authoritative, high-yield coverage of: Etiology and epidemiology Clinically relevant pathophysiology Signs & Symptoms o Differential Diagnosis Physical and Laboratory Findings Therapeutics o Practice GuidelinesNEW FEATURESFull-color presentation for the first time!Full-color images of clinical conditions encountered in dermatology, cardiology, and eye diseases New chapters on end-of-life care, congenital heart disease in the adult patient, non-invasive cardiac examination, and metabolic syndromeLook for these other great Harrison's titles:Harrison's Principles of Internal Medicine, 17eHarrison's Online available through Accessmedicine.com

    News of both the Ice Man's discovery and his age, which was put at over five thousand years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative of a man who died thousands of years ago?In The Seven Daughters of Eve, he gives us a firsthand account of his research into a remarkable gene, which passes undiluted from generation to generation through the maternal line. After plotting thousands of DNA sequences from all over the world, Sykes found that they clustered around a handful of distinct groups. Among Europeans and North American Caucasians, there are, in fact, only seven. This conclusion was staggering: almost everyone of native European descent, wherever they may live throughout the world, can trace their ancestry back to one of seven women, the Seven Daughters of Eve.Naming them Ursula, Xenia, Helena, Velda, Tara, Katrine, and Jasmine, Sykes has created portraits of their disparate worlds by mapping the migratory patterns followed by millions of their ancestors. In reading the stories of these seven women, we learn exactly how our origins can be traced, how and where our ancient genetic ancestors lived, and how we are each living proof of the almost indestructible strands of DNA, which have survived over so many thousands of years. Indeed, The Seven Daughters of Eve is filled with dramatic stories: from Sykes's identification, using DNA samples from two living relatives, of the remains of Tsar Nicholas and Tsaress Alexandra, to the Caribbean woman whose family had been sold into slavery centuries before and whose ancestry Sykes was able to trace back to the Eastern coast of central Africa. Ultimately, Sykes's investigation reveals that, as a race, what humans have in common is more deeply embedded than what separates us.

    It’ll have you scratching your head wondering why we even bother to go to school.Think Magellan was the first man to circumnavigate the globe, baseball was invented in America, Henry VIII had six wives, Mount Everest is the tallest mountain? Wrong, wrong, wrong, and wrong again. You’ll be surprised at how much you don’t know! Check out THE BOOK OF GENERAL IGNORANCE for more fun entries and complete answers to the following:How long can a chicken live without its head?About two years.What do chameleons do?They don’t change color to match the background. Never have; never will. Complete myth. Utter fabrication. Total Lie. They change color as a result of different emotional states.How many legs does a centipede have?Not a hundred.How many toes has a two-toed sloth?It’s either six or eight.Who was the first American president?Peyton Randolph.What were George Washington’s false teeth made from?Mostly hippopotamus.What was James Bond’s favorite drink?Not the vodka martini.

    Myers. Book also includes Social Sense Discovery Channel insert (CD that is sealed)

    This book is an easy-to-understand and fun reference to this challenging subject. It explains the principles of organic chemistry in simple terms and includes worked-out problems to help readers get up to speed on the basics.

    point-by-point at the end of the chapters and noted in the assignment material. More logically, the chapter on the analysis of financial statements is now placed immediately after the chapter on financial statements, enabling students to use rational analysis to interpret material while it is still fresh in their minds. An instructor's manual is also available.

    It introduces the analysis of the key elements of language--sounds, words, structures and meanings, and provides a solid foundation in all of the essential topics. The third edition has been extensively revised to include new sections on important contemporary issues in language study, including language and culture, African American English, sign language, and slang. A comprehensive glossary provides useful explanations of technical terms, and each chapter contains a range of new study questions and research tasks, with suggested answers.

    For over half a century, the MLA Handbook is the guide millions of writers have relied on.The seventh edition is a comprehensive, up-to-date guide to research and writing in the online environment. It provides an authoritative update of MLA documentation style for use in student writing, including simplified guidelines for citing works published on the Web and new recommendations for citing several kinds of works, such as digital files and graphic narratives.Every copy of the seventh edition of the MLA Handbook comes with a code for accessing the accompanying Web site. New to this edition, the Web site provides- the full text of the print volume of the MLA Handbook- over two hundred additional examples- several research-project narratives--stories, with sample papers, that illustrate the steps successful students take in researching and writing papers- searching of the entire site, including the full text of the MLA Handbook- continuous access throughout the life of the seventh edition of the MLA Handbook

    Following in the fashion of Stephen Jay Gould and Peter Medawar, one of the world's leading scientists examines how "pure science" is in fact shaped and guided by social and political needs and assumptions.

    Drawing on 40 years of experience of presenting art to the public, Marilyn Stokstad offers this comprehensive look at art in all of its diversity, from paintings and architecture to tapestries, jewellery and electronic art.

    The author analyzes both historical and contemporary trends, as well as the major theories used to explain the dynamics underlying international relations--helping you to think critically about these topics by presenting rival views. From global development, the practice of terrorism, and the war in Iraq to peacekeeping operations and the transformations evident since 9/11, this thought-provoking textbook briefs you on the most recent indicators of global trends. An extensive map, figure, and photo program helps you visualize the significance of statistical data and the implications of global rivalries.

    Newly streamlined, its signature engaging, and jargon-free instruction emphasizes cultural currency, humor, and visual argument. Students love Everything's an Argument because it helps them understand how a world of argument already surrounds them; instructors love it because it helps students construct their own personally meaningful arguments about that world. The print text is now integrated with e-Pages for Everything's an Argument, designed to take advantage of what the Web can do. Also available in a brief version without the reader and as an e-Book.

    This text covers the basics of emerging areas in power electronics and a broad range of topics such as power switching devices, conversion methods, analysis and techniques, and applications. Its unique approach covers the characteristics of semiconductor devices first, then discusses the applications of these devices for power conversions. Four main applications are included: flexible ac transmissions (FACTs), static switches, power supplies, dc drives, and ac drives. - New chapters - Including Ch. 9, Multilevel Inverters, Ch. 13, Flexible AC Transmission Systems, and Ch. 17, Gate Drive Circuits.', gives students the latest information available on these topics. - New sections throughout - Including Semiconductor Basics, State-Space Analysis of Regulators, Vector Controls, Stepper Motor Control and more, gives students the latest information available on these topics. - Well-written and easy-to-follow, helps students maintain interest in the text. - Numerous worked-out examples, demonstrates for students the applications of conversion techniques in design and analysis of converter cir

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.