Pandora's Lab: Seven Stories of Science Gone Wrong


Paul A. Offit - 2017
    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

Chaos: Making a New Science


James Gleick - 1987
    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.

What Evolution Is


Ernst W. Mayr - 1940
    Science Masters Series

The Evolution of Cooperation


Robert Axelrod - 1984
    Widely praised and much-discussed, this classic book explores how cooperation can emerge in a world of self-seeking egoists—whether superpowers, businesses, or individuals—when there is no central authority to police their actions. The problem of cooperation is central to many different fields. Robert Axelrod recounts the famous computer tournaments in which the “cooperative” program Tit for Tat recorded its stunning victories, explains its application to a broad spectrum of subjects, and suggests how readers can both apply cooperative principles to their own lives and teach cooperative principles to others.

Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing


Kevin Davies - 2020
    For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change.Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code.Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

Life: A Natural History of the First Four Billion Years of Life on Earth


Richard Fortey - 1997
    . . . Anyone with the slightest interest in biology should read this book."--The New York Times Book Review"A marvelous museum of the past four billion years on earth--capacious, jammed with treasures, full of learning and wide-eyed wonder."--The Boston GlobeFrom its origins on the still-forming planet to the recent emergence of Homo sapiens--one of the world's leading paleontologists offers an absorbing account of how and why life on earth developed as it did. Interlacing the tale of his own adventures in the field with vivid descriptions of creatures who emerged and disappeared in the long march of geologic time, Richard Fortey sheds light upon a fascinating array of evolutionary wonders, mysteries, and debates. Brimming with wit, literary style, and the joy of discovery, this is an indispensable book that will delight the general reader and the scientist alike."A drama bolder and more sweeping than Gone with the Wind . . . a pleasure to read."--Science"A beautifully written and structured work . . . packed with lucid expositions of science."--Natural History

The Human Brain: A Guided Tour (Science Masters)


Susan A. Greenfield - 1997
    What would you see if you removed the skull from the human brain and then slowly worked your way deeper and deeper into the brain, to the level of an individual neuron? With renowned brain researcher Susan Greenfield as your guide, here is your chance to gain a bird's eye view of the human brain—and to learn more about what the brain is, how it works, what happens when one part of the brain is made dysfunctional through stroke or accident, how brain mood-modifying drugs find their targets.In a particularly fascinating chapter, Greenfield surveys for us how a brain is built and then takes us on a tour of the developing brain from the moment of conception.Throughout Greenfield poses the larger questions all readers want to consider, including: At what stage does individuality creep into the developing brain? How does the collection of circuits of neurons give rise not just to an individual brain but an individual consciousness? What might a fetus be conscious of?

The Meme Machine


Susan Blackmore - 1999
    The meme is also one of the most important--and controversial--concepts to emerge since 'The Origin of the Species' appeared nearly 150 years ago.In 'The Meme Machine' Susan Blackmore boldly asserts: "Just as the design of our bodies can be understood only in terms of natural selection, so the design of our minds can be understood only in terms of memetic selection." Indeed, Blackmore shows that once our distant ancestors acquired the crucial ability to imitate, a second kind of natural selection began, a survival of the fittest amongst competing ideas and behaviors. Ideas and behaviors that proved most adaptive - making tools, for example, or using language--survived and flourished, replicating themselves in as many minds as possible. These memes then passed themselves on from generation to generation by helping to ensure that the genes of those who acquired them also survived and reproduced. Applying this theory to many aspects of human life, Blackmore offers brilliant explanations for why we live in cities, why we talk so much, why we can't stop thinking, why we behave altruistically, how we choose our mates, and much more.With controversial implications for our religious beliefs, our free will, our very sense of "self," 'The Meme Machine' offers a provocative theory everyone will soon be talking about.

The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race


Walter Isaacson - 2021
    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

Why We Get Sick: The New Science of Darwinian Medicine


Randolph M. Nesse - 1994
    Why We Get Sick compels readers to reexamine the age-old attitudes toward sickness. Line drawings.

Napoleon's Buttons: How 17 Molecules Changed History


Penny Le Couteur - 1991
    When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today


David P. Clark - 2004
    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

The Naked Ape


Desmond Morris - 1967
    Here is the Naked Ape at his most primal in love, at work, at war. Meet man as he really is: relative to the apes, stripped of his veneer as we see him courting, making love, sleeping, socializing, grooming, playing. The Naked Ape takes its place alongside Darwin’s Origin of the Species, presenting man not as a fallen angel, but as a risen ape, remarkable in his resilience, energy and imagination, yet an animal nonetheless, in danger of forgetting his origins. With its penetrating insights on man's beginnings, sex life, habits and our astonishing bonds to the animal kingdom, The Naked Ape is a landmark, at once provocative, compelling and timeless.

Herding Hemingway's Cats: Understanding how our genes work


Kat Arney - 2016
    We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.

Darwin's Ghosts: The Secret History of Evolution


Rebecca Stott - 2012
    . . a book that enriches our understanding of how the struggle to think new thoughts is shared across time and space and people.”—The Sunday Telegraph (London)Christmas, 1859. Just one month after the publication of On the Origin of Species, Charles Darwin received an unsettling letter. He had expected criticism; in fact, letters were arriving daily, most expressing outrage and accusations of heresy. But this letter was different. It accused him of failing to acknowledge his predecessors, of taking credit for a theory that had already been discovered by others. Darwin realized that he had made an error in omitting from Origin of Species any mention of his intellectual forebears. Yet when he tried to trace all of the natural philosophers who had laid the groundwork for his theory, he found that history had already forgotten many of them.Darwin’s Ghosts tells the story of the collective discovery of evolution, from Aristotle, walking the shores of Lesbos with his pupils, to Al-Jahiz, an Arab writer in the first century, from Leonardo da Vinci, searching for fossils in the mine shafts of the Tuscan hills, to Denis Diderot in Paris, exploring the origins of species while under the surveillance of the secret police, and the brilliant naturalists of the Jardin de Plantes, finding evidence for evolutionary change in the natural history collections stolen during the Napoleonic wars. Evolution was not discovered single-handedly, Rebecca Stott argues, contrary to what has become standard lore, but is an idea that emerged over many centuries, advanced by daring individuals across the globe who had the imagination to speculate on nature’s extraordinary ways, and who had the courage to articulate such speculations at a time when to do so was often considered heresy.With each chapter focusing on an early evolutionary thinker, Darwin’s Ghosts is a fascinating account of a diverse group of individuals who, despite the very real dangers of challenging a system in which everything was presumed to have been created perfectly by God, felt compelled to understand where we came from. Ultimately, Stott demonstrates, ideas—including evolution itself—evolve just as animals and plants do, by intermingling, toppling weaker notions, and developing over stretches of time. Darwin’s Ghosts presents a groundbreaking new theory of an idea that has changed our very understanding of who we are.