Her pioneering research on how the chemicals inside our bodies form a dynamic information network, linking mind and body, is not only provocative, it is revolutionary. By establishing the biomolecular basis for our emotions and explaining these new scientific developments in a clear and accessible way, Pert empowers us to understand ourselves, our feelings, and the connection between our minds and our bodies -- body-minds -- in ways we could never possibly have imagined before. Molecules of Emotion is a landmark work, full of insight and wisdom and possessing that rare power to change the way we see the world and ourselves.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    She stopped sleeping and eating, and began to hallucinate--Michael Jackson wearing masks, demonically cackling Muppets, and faces in windows. She wrote manifestos and math equations in her diary, and infographics on her wall. Eventually hospitalized and diagnosed as bipolar, her prescribed medication was three pink pills -- lithium. In Grand Delusions, Lowe shares her story of life-long episodic madness and the stability she found with lithium, as well as a journalistic exploration of the history and science of the mysterious element. She interviews scientists, psychiatrists, and patients to examine how effective lithium really is and how its side effects can be dangerous for long-term users. Lowe travels to the Bolivian salt mines that hold over half of the world's lithium reserves, as well as to rural America, where turn of the century lithium spas are still touted as a tonic to cure all ills. At the heart of Grand Delusions is Lowe's personal story, detailing her experiences on and off lithium, and the mental health and personal struggles that have accompanied it. Most recently, the longterm effects of lithium have led to her kidney degradation. Now adjusting to new medication after 20 years of lithium, Lowe's pursuit of a stable life continues. Grand Delusions is eye-opening and powerful, tackling an illness and drug that has touched millions of lives and yet remains shrouded in social stigma. With unflinching honesty, Lowe allows us a clear-eyed view into her life, while also offering a compelling historical overview of one of mankind's oldest medical mysteries."

     This clever and pithy book challenges introverts to take ownership of their personalities...with quiet strength. Sophia Dembling asserts that the introvert’s lifestyle is not “wrong” or lacking, as society or extroverts would have us believe. Through a combination of personal insights and psychology, The Introvert’s Way helps and encourages introverts to embrace their nature, to respect traits they may have been ashamed of and reframe them as assets. You’re not shy; rather, you appreciate the joys of quiet. You’re not antisocial; instead, you enjoy recharging through time alone. You’re not unfriendly, but you do find more meaning in one-on-one connections than large gatherings. By honoring what makes them unique, this astute and inspiring book challenges introverts to “own” their introversion, igniting a quiet revolution that will change how they see themselves and how they engage with the world.

    Mood-stabilising medication is routinely prescribed to adults and children alike, with child prescriptions this decade increasing by 400% and overall diagnoses by 4000%.What could explain this explosion of bipolarity? Is it a legitimate diagnosis or the result of Big Pharma marketing? Exploring these questions, Darian Leader challenges the rise of 'bipolar' as a catch-all solution to complex problems, and argues that we need to rethink the highs and lows of mania and depression.What, he asks, do these experiences have to do with love, guilt and rage? Why the spending sprees and the intense feeling of connection with the world? Why the confidence, the self-esteem and the sense of a bright future that can so swiftly turn into despair and dejection?Only by looking at these questions in a new way will we be able to understand and help the person caught between feelings that can be so terrifying and so exhilarating, so life-affirming yet also so lethal.Strictly Bipolar is essential reading for anyone interested in contemporary views of the self, bipolarity and a deeper understanding of manic-depression.Praise for What is Madness?:'Lucid, excellent' Adam Phillips, London Review of Books'Leader is as much a philosopher as a psychoanalyst and his ideas are engrossing and enlightening' Metro'Fascinating . . . [Leader has] a formidable grasp of psychiatric history and a storyteller's flair for detail . . . a humane and timely book' New Statesman'The mad . . . have been segregated and often confined; for fear, perhaps, that they will contaminate the rest of us. But as Darian Leader brilliantly shows, things are never so simple' Hanif Kureshi, IndependentDarian Leader is a psychoanalyst practising in London and a member of the Centre for Freudian Analysis and Research and of the College of Psychoanalysts - UK. He is the author of What is Madness?, The New Black, Why do women write more letters than they post?, Promises lovers make when it gets late, Freud's Footnotes and Stealing the Mona Lisa, and co-author, with David Corfield, of Why Do People Get Ill? He is Honorary Visiting Professor in the School of Human and Life Sciences, Roehampton University.

    Packed with surprising insight into the reasons we drink, it will open your eyes to the startling role of alcohol in our culture. Annie Grace brilliantly weaves psychological, neurological, cultural, social and industry factors with her extraordinarily candid journey resulting in a must read for anyone who drinks. This book, without scare tactics, pain or rules, gives you freedom from alcohol. By addressing causes rather than symptoms it is a permanent solution rather than lifetime struggle. The Alcohol Experiment: There are a million reasons why you might drink. It tastes great. You feel more sociable. Sex is better. It helps you relax. But are you really in control? Whether you’re reading this because you know you drink too much and want to quit, or whether you just want to cut back for a while, this book is for you.The Alcohol Experiment is a 30-day programme with a difference. Each day, it will show you a new way of thinking about booze, and ask you to look a little closer at why we drink, what we get out of it, and whether it’s really the alcohol that’s giving us what we want.

    Its name is shame.Whether we realize it or not, shame affects every aspect of our personal lives and vocational endeavors. It seeks to destroy our identity in Christ, replacing it with a damaged version of ourselves that results in unhealed pain and brokenness. But God is telling a different story for your life.Psychiatrist Curt Thompson unpacks the soul of shame, revealing its ubiquitous nature and neurobiological roots. He also provides the theological and practical tools necessary to dismantle shame, based on years of researching its damaging effects and counseling people to overcome those wounds.Thompson's expertise and compassion will help you identify your own pains and struggles and find freedom from the lifelong negative messages that bind you. Rewrite the story of your life and embrace healing and wholeness as you discover and defeat shame's insidious agenda.

    She tried everything to appease her wakefulness: from medication to therapy, changes in her diet to changes in her living arrangements. Nothing seemed to help.The Shapeless Unease is Harvey's darkly funny and deeply intelligent anatomy of her insomnia, an immersive interior monologue of a year without one of the most basic human needs. Original and profound, and narrated with a lucid breathlessness, this is a startlingly insightful exploration of memory, writing and influence, death and the will to survive, from "this generation's Virginia Woolf" (Telegraph).

    It explores the use of art to survive abuse, incest, madness and depression, and the often deep-seated impulse toward self-destruction including cutting, eating disorders, and addiction. Here, some of our most compelling cartoonists, novelists, poets, dancers, playwrights, and burlesque performers traverse the pains and passions that can both motivate and destroy women artists, and mark a path for survival. Taken together, these artful reflections offer an honest and hopeful journey through a woman's silent rage, through the power inherent in struggles with destruction, and the ensuing possibilities of transforming that burning force into the external release of art. With contributions by Nan Goldin, bell hooks, Patricia Smith, Cristy C. Road, Carol Queen, Annie Sprinkle, Elizabeth Stephens, Carolyn Gage, Eileen Myles, Fly, Diane DiMassa, Bonfire Madigan Shive, Inga Muscio, Kate Bornstein, Toni Blackman, Nicole Blackman, Silas Howard, Daphne Gottleib, and Stephanie Howell.

    You might say you're introverted or awkward, or that you're fine around friends but just can't speak up in a meeting or at a party. Maybe you're usually confident but have recently moved or started a new job, only to feel isolated and unsure.If you get nervous in social situations--meeting your partner's friends, public speaking, standing awkwardly in the elevator with your boss--you've probably been told, "Just be yourself!" But that's easier said than done--especially if you're prone to social anxiety.Weaving together cutting-edge science, concrete tips, and the compelling stories of real people who have risen above their social anxiety, Dr. Ellen Hendriksen proposes a groundbreaking idea: you already have everything you need to succeed in any unfamiliar social situation. As someone who lives with social anxiety, Dr. Hendriksen has devoted her career to helping her clients overcome the same obstacles she has. With familiarity, humor, and authority, Dr. Hendriksen takes the reader through the roots of social anxiety and why it endures, how we can rewire our brains through our behavior, and--at long last--exactly how to quiet your Inner Critic, the pesky voice that whispers, "Everyone will judge you." Using her techniques to develop confidence, think through the buzz of anxiety, and feel comfortable in any situation, you can finally be your true, authentic self.

    Weed. Bud. Whatever you choose to call it, it’s been a health aid, comfort, and life-enhancer for humankind for more than three thousand years. But while cannabis is used by hundreds of millions of people around the world, more than a century of prohibition has resulted in confusion about its status: Is it healthy? Is it medicinal? Will it make you crazy?In this fun, illuminating book, cannabis journalist Amanda Siebert delves deep into the latest research to separate marijuana fact from fiction, revealing ten evidence-based ways this potent little plant can improve your life. She speaks with some of the world’s top researchers, medical professionals, and consultants to answer questions such as: Can cannabis help you get a full night’s sleep? Does it aid in exercise and weight loss? Can it really cure cancer? She also offers practical advice for enjoying its benefits, including easy-to-follow, step-by-step instructions for consumption and dosage, as well as examples of real people who have used this drug to enhance their lives. Cannabis, it turns out, could be life-changing: it can enrich any diet, slow down aging, and even spice things up in the bedroom.

    As recently as 1918, a pandemic of influenza claimed over 50 million lives worldwide. The advent of drugs and vaccines led to an era of hope when we thought our battles with infectious disease were won, but our optimism has been eroded by the recognition that many pathogens have the capacity to transform themselves and escape our efforts to eradicate them. Are we now facing an inevitable repeat of a calamity such as the 1918 influenza pandemic or the Black Death? Can we anticipate and thwart such an event, or are we wilfully creating the conditions that would promote the emergence of new and highly virulent human infectious disease?Sunetra Gupta is Professor of Theoretical Epidemiology at the University of Oxford specialising in infectious diseases. She holds a bachelor's degree from Princeton University and a Ph.D. from the University of London. She has been awarded the Scientific Medal by the Zoological Society of London and the Royal Society Rosalind Franklin Award for her scientific research. She is also a novelist whose books have been awarded the Sahitya Akademi Award, the Southern Arts Literature Prize, shortlisted for the Crossword Award, and longlisted for the DSC and Orange Prizes.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    Providing an insider perspective, they share their personal experiences of mental illness and unpack the current knowledge about conditions and treatments. What do we know? What don’t we know? How do we get help? What actually works?Punctuated with anecdotes, real-life stories and reflections on the cultural and historical context, Mental is an irreverent and entertaining guide to the full spectrum of mental health issues – from depression and anxiety to schizophrenia, personality disorders and substance abuse.Set to become a go-to guide for anyone with a mental illness or supporting someone who has one, Mental breaks the taboos around mental health and offers clear practical advice on how to live successfully.

    James Morrison details effective methods for posing clinical questions; what the clinician should ask to obtain complete, accurate information; and how to select the best strategy to meet any clinical situation. Throughout, the author interweaves research on what works in mental health interviewing along with fresh insights on how to build rapport and enhance patient motivation.