The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    This text provides a basic treatment of discrete-event simulation, including the proper collection and analysis of data, the use of analytic techniques, verification and validation of models, and designing simulation experiments. It offers an up-to-date treatment of simulation of manufacturing and material handling systems, computer systems, and computer networks. Students and instructors will find a variety of resources at the associated website, www.bcnn.net, including simulation source code for download, additional exercises and solutions, web links and errata.

    Your puppy should be socialized to a wide variety of people, especially children, men, and strangers, before he is twelve weeks old. 2. Your puppy must learn to inhibit the force of his bites and develop a "soft mouth" before he is eighteen weeks old. 3. You must prevent predictable adolescent problems. Veterinarian and animal behaviorist Dr. Ian Dunbar is the original creator of off-leash puppy classes, which sparked the revolution for positive, reward-based, dog-friendly dog training.

    Sleep patterns may be the most obvious manifestation of the highly individualized biological clocks we inherit, but these clocks also regulate bodily functions from digestion to hormone levels to cognition. Living at odds with our internal timepieces, Till Roenneberg shows, can make us chronically sleep deprived and more likely to smoke, gain weight, feel depressed, fall ill, and fail geometry. By understanding and respecting our internal time, we can live better.Internal Time combines storytelling with accessible science tutorials to explain how our internal clocks work—for example, why morning classes are so unpopular and why “lazy” adolescents are wise to avoid them. We learn why the constant twilight of our largely indoor lives makes us dependent on alarm clocks and tired, and why social demands and work schedules lead to a social jet lag that compromises our daily functioning.Many of the factors that make us early or late “chronotypes” are beyond our control, but that doesn’t make us powerless. Roenneberg recommends that the best way to sync our internal time with our external environment and feel better is to get more sunlight. Such simple steps as cycling to work and eating breakfast outside may be the tickets to a good night’s sleep, better overall health, and less grouchiness in the morning.[Description taken from publisher's web site.]

    What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound:• A figure skater whose body has become a ticking time-bomb • A salesman who drives around and around a traffic rotary, unable to get off • A college quarterback who can't stop calling the same play • A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive • A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth livingHow does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance.

    The book uses the theme of evolution to develop a broad-scale view of animal diversity--students focus not only the organisms themselves, but also the processes that produce evolutionary diversity. The book is unique in its comprehensive survey of zoological diversity and its emphasis on evolutionary, systematic and ecological principles, all in one package.

    Taking us through a typical day, from the arousal of the senses in the morning to the reverie of sleep and dreams, Ackerman reveals the human form as we’ve never seen it: busy, cunning, and miraculous. Advances in genetics and medical imaging have allowed us to peer more deeply inside ourselves than ever before, revealing that we are intensely rhythmic creatures. The human body is like a clock ― an entire shop of clocks, actually ― measuring out the seconds, minutes, days, and seasons of life. Ackerman shows the importance of synchronising our actions with our biological rhythms ― and how defying them can cause us real harm. We learn the best time of day to drink a cocktail, take a nap, run a race, give a presentation, and take medication, along with a host of other curious facts, such as why you succumb to a cold and your spouse doesn’t, even though you’ve both been exposed to the same sick child. Did you know that you can tell time in your sleep? Or that up to half of the calories you consume can be burned off by fidgeting? That women have more nightmares than men? That tuna, sardines, and walnuts may ease depression? At once entertaining and deeply practical, this fascinating book will make you think of your body in an entirely new way.

                Gut Reactions by chemist Simon Quellen Field shows readers how their bodies react to food and the environment and how their brains affect what and how much they eat. It reveals why some diets work for some people but not for others, based on genetics, previous weight history, brain chemistry, environmental cues, and social pressures. It explores how dozens of hormones affect hunger and satiety and interact with the brain and the gut to regulate feeding behavior. And it explains the addictive nature of foods that interact with the same dopamine and opioid receptors in the brain as cocaine, heroin, amphetamines, and nicotine.             Whether you’re looking to lose weight, put on muscle mass, or simply understand how your metabolism or gut microbiome impact your food cravings, Simon Quellen Field has the scientific answers for you.

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    . . a skier submerged for an hour in a frozen Norwegian lake . . . a comatose brain surgery patient whom doctors have declared a "vegetable."Twenty years ago all of them would have been given up for dead, with no realistic hope for survival. But today, thanks to incredible new medical advances, each of these individuals is alive and well . . .Cheating Death.In this riveting book, Dr. Sanjay Gupta-neurosurgeon, chief medical correspondent for CNN, and bestselling author-chronicles the almost unbelievable science that has made these seemingly miraculous recoveries possible. A bold new breed of doctors has achieved amazing rescues by refusing to accept that any life is irretrievably lost. Extended cardiac arrest, "brain death," not breathing for over an hour-all these conditions used to be considered inevitably fatal, but they no longer are. Today, revolutionary advances are blurring the traditional line between life and death in fascinating ways.Drawing on real-life stories and using his unprecedented access to the latest medical research, Dr. Gupta dramatically presents exciting accounts of how pioneering physicians and researchers are altering our understanding of how the human body functions when it comes to survival-and why more and more patients who once would have died are now alive. From experiments with therapeutic hypothermia to save comatose stroke or heart attack victims to lifesaving operations in utero to the study of animal hibernation to help wounded soldiers on far-off battlefields, these remarkable case histories transform and enrich all our assumptions about the true nature of death and life.

    Hansen, PhD. Using this interactive coloring workbook, you can trace arteries, veins, and nerves through their courses and bifurcations...reinforce your understanding of muscle origins and insertions from multiple views and dissection layers...and develop a better understanding of the integration of individual organs in the workings of each body system throughout the human form. Online access to Student Consult-where you'll find the complete contents of the book and much more-further enhances your study and exponentially boosts your reference power. Whether you are taking an anatomy course or just curious about how the body works, let the art of Netter guide you!Provides multiple views, magnifications, and dissection layers that strengthen your understanding of 3-D anatomical relationships.Presents each topic in two-page spreads-with Netter anatomical illustrations accompanied by high-yield information-that gives context to the structures.Features illustrations small enough for quick coloring, but large enough to provide you with important details.Offers tips for coloring key structures that emphasize how a coloring exercise can reinforce learning.Uses Key Points to cover functional and clinical relevance and relationships.Contains tables that review muscle attachments, innervation, action, and blood supply.Features Clinical Notes which highlight the importance of anatomy in medicine.Includes online access to Student Consult where you can search the complete contents of the book, print additional copies of the coloring pages, view completed coloring pages for reference, access Integration Links to bonus content in other Student Consult titles...and much more...to further enhance your study and exponentially boost your reference power.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Michael Savage explains the origins of viruses and their impact on the U.S. With new and resurgent diseases resulting from unregulated immigration and a politicized public health system, Michael Savage sees the need for some changes - starting with the President and the Center for Disease Control telling us the truth. Savage makes his case for the government to enforce travel bans, the use of quarantines and the importance of proper border screenings. However, this is not a cure or treatment for any of these diseases. With Zika virus, tuberculosis, hepatitis, Enterovirus 68 and other new disease threats emerging across the U.S., Savage will explain ways to fortify your immune system and defend against these and other diseases. Drawing from his extensive training, Dr. Savage examines the benefits of using specific nutrients to boost the human immune system which, in turn, increases the odds of surviving a viral infection as well as preventing other diseases. Based on his knowledge of the politics of medicine being played by the Obama mandarins and his Ph.D. in Epidemiology and Nutrition from the University of California, Berkley, Dr. Savage presents solid information to protect your health. Whether you want to defend your body against deadly diseases, boost your immunity, or learn more about the government's impact on reemerging and imported diseases, DISEASES WITHOUT BORDERS is your source for informative, helpful, and potentially life-saving advice.

    Do you want your students to just take psychology or to experience psychology? Laura King's approach to introductory psychology embodies a balanced consideration of functioning behavior as well as dysfunction and a view of psychology as an integrated whole.