The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Featuring singing materials from folk music and the literature of composed music.

    Now in it's tenth edition, this text makes chemistry exciting to students by showing them why important concepts are relevant to their lives and future careers.

    Fueled by the authors' conviction that skills inform principles; principles inform skills, Interpersonal Communication: Relating to Others maintains a careful balance between theoretical and skills-oriented material. This book integrates a key emphasis on diversity with examples drawn from a variety of age and ethnic groups and special boxes that focus on gender and diversity issues. A chapter on intercultural communication supplements this integral material by relating it to the other-oriented approach

    With a focus on the big picture of human evolution, the text helps students master the basic principles of the subject and arrive at an understanding of the human species and its place in the biological world. This book continues to keep pace with changes in the field by including thorough coverage of cutting-edge advances in molecular biology and genomics, expanded material on modern human biology, and the latest in new fossil finds.

    Stewart's Calculus is successful throughout the world because he explains the material in a way that makes sense to a wide variety of readers. His explanations make ideas come alive, and his problems challenge, to reveal the beauty of calculus. Stewart's examples stand out because they are not just models for problem solving or a means of demonstrating techniques--they also encourage readers to develp an analytic view of the subject. This edition includes new problems, examples, and projects. This version of Stewart's book introduced exponential and logarithmic functions in the first chapter and their limits and derivatives are found in Chapters 2 and 3.

    Time-saving study tools help readers arrive at a complete understanding of human anatomy. KEY TOPICS: An Introduction to Anatomy, The Cell, Tissues and Early Embryology, The Integumentary System, The Skeletal System: Osseous Tissue and Skeletal Structure, The Skeletal System: Axial Division, The Skeletal System: Appendicular Division, The Skeletal System: Articulations, The Muscular System: Skeletal Muscle Tissue and Muscle Organization, The Muscular System: Axial Musculature, The Muscular System: Appendicular Musculature, Surface Anatomy and Cross-Sectional Anatomy, The Nervous System: Neural Tissue, The Nervous System: The Spinal Cord and Spinal Nerves, The Nervous System: The Brain and Cranial Nerves, The Nervous System: Pathways And Higher-Order Functions, The Nervous System:  Autonomic Division, The Nervous System: General and Special Senses, The Endocrine System, The Cardiovascular System: Blood, The Cardiovascular System: The Heart, The Cardiovascular System: Vessels and Circulation, The Lymphoid System, The Respiratory System, The Digestive System, The Urinary System, The Reproductive System, The Reproductive System: Embryology and HumanDevelopment. MARKET: For all readers interested in human anatomy.

    Many new or revised figures and photographs, study questions and a glossary of key terms have been added.

    This Penguin Classics edition is edited with an introduction by James Moore and Adrian Desmond.In The Origin of Species, Charles Darwin refused to discuss human evolution, believing the subject too 'surrounded with prejudices'. He had been reworking his notes since the 1830s, but only with trepidation did he finally publish The Descent of Man in 1871. The book notoriously put apes in our family tree and made the races one family, diversified by 'sexual selection' - Darwin's provocative theory that female choice among competing males leads to diverging racial characteristics. Named by Sigmund Freud as 'one of the ten most significant books' ever written, Darwin's Descent of Man continues to shape the way we think about what it is that makes us uniquely human.In their introduction, James Moore and Adrian Desmond, acclaimed biographers of Charles Darwin, call for a radical re-assessment of the book, arguing that its core ideas on race were fired by Darwin's hatred of slavery. The text is the second and definitive edition and this volume also contains suggestions for further reading, a chronology and biographical sketches of prominent individuals mentioned.Charles Darwin (1809-82), a Victorian scientist and naturalist, has become one of the most famous figures of science to date. The advent of On the Origin of Species by Means of Natural Selection in 1859 challenged and contradicted all contemporary biological and religious beliefs.If you enjoyed The Descent of Man, you might like Darwin's On the Origin of Species, also available in Penguin Classics.

    Laura M. Ahearn shows that young Nepalese people are applying their newly acquired literacy skills to love-letter writing, fostering a transition that involves not only a shift in marriage rituals, but also a change in how villagers conceive of their own ability to act and attribute responsibility for events. These developments have potential ramifications that extend far beyond the realm of marriage and well past the Himalayas.The love-letter correspondences examined by Ahearn also provide a deeper understanding of the social effects of literacy. While the acquisition of literary skills may open up new opportunities for some individuals, such skills can also impose new constraints, expectations, and disappointments. The increase in female literacy rates in Junigau in the 1990s made possible the emergence of new courtship practices and facilitated self-initiated marriages, but it also reinforced certain gender ideologies and undercut some avenues to social power, especially for women. Scholars, and students in such fields as anthropology, women's studies, linguistics, development studies, and South Asian studies will find this book ethnographically rich and theoretically insightful. Laura M. Ahearn is Assistant Professor of Anthropology, Rutgers University.

    This approach will captivate students and encourage them to think critically about the nature of public administration today. Introducing Public Administration provides students with a solid, conceptual foundation in public administration, and contains the latest information on important trends in the discipline. To further engage students and deepen interest in its narrative, the text uses unique chapter-opening vignettes called Keynotes, chapter ending case studies, and a series of boxes throughout that offer real-life excerpts and alternative theories.

    The engaging articles on all key issues related to the anthropology of religion grab the attention of students, while giving them an excellent foundation in contemporary ideas and approaches in the field. The multiple authors included in each chapter represent a range of interests, geographic foci, and ways of looking at each subject. Divided into ten chapters, this book begins with a broad view of anthropological ways of looking at religion, and moves on to some of the core topics within the subject, such as myth, ritual, and the various types of religious specialists.

    It explores the critical concepts while also examining why they are relevant. The core content is presented within the framework of predicting products, proposing mechanisms, and solving synthesis problems. Readers will fine-tune the key skills involved in solving those types of problems with the help of interactive, step-by-step instructions and problems.

    Fields Cookies... What backward messages on records are really trying to tell you... Frank Sinatra's real age... Why you can't counterfeit a lottery ticket... Barbra Streisand's blue movie... The other Boy Scout rituals... Ingmar Bergman's soap commercials... The formula for Play-Doh... and more.

    It Combines Comprehensive Medical Content With Dynamic New Features And Interactive Technology To Better Support Instructors And To Help Prepare Students For The Field. An Interactive Skills DVD Is Also Packaged Free With Each Copy Of The Text.