Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    She startles awake, saying his name. It is always about him: one of her closest high school friends, a boy named Mark. A boy who raped her.When her nightmares worsen, Jeannie decides—after fourteen years of silence—to reach out to Mark. He agrees to talk on the record and meet in person. "It's the least I can do," he says.Jeannie details her friendship with Mark before and after the assault, asking the brave and urgent question: Is it possible for a good person to commit a terrible act? Jeannie interviews Mark, exploring how rape has impacted his life as well as her own. She examines the language surrounding sexual assault and pushes against its confines, contributing to and deepening the #MeToo discussion.Exacting and courageous, Things We Didn't Talk About When I Was a Girl is part memoir, part true crime record, and part testament to the strength of female friendships—a recounting and reckoning that will inspire us to ask harder questions and interrogate our biases. Jeannie Vanasco examines and dismantles long-held myths of victimhood, discovering grace and power in this genre-bending investigation into the trauma of sexual violence.

    She was also generous. When Anna proposed an all-expenses-paid trip to Marrakech, Rachel jumped at the chance. But when Anna’s credit cards mysteriously stopped working, the dream vacation quickly took a dark turn. Anna asked Rachel to begin fronting costs—first for flights, then meals and shopping, and, finally, for their $7,500-per-night private villa. Before Rachel knew it, more than $62,000 had been charged to her credit cards. Anna swore she would reimburse Rachel the moment they returned to New York. Back in Manhattan, the repayment never materialized, and a shocking pattern of deception emerged. Rachel learned that Anna had left a trail of deceit—and unpaid bills—wherever she’d been. Mortified, Rachel contacted the district attorney, and in a stunning turn of events, found herself helping to bring down one of the city’s most notorious con artists.

    Her hilarious and deeply relatable look at the challenges of womanhood in a changing world became a cultural touchstone for women everywhere. Now Guisewite returns with her signature wit and warmth in this debut essay collection about another time of big transition, when everything starts changing and disappearing without permission: aging parents, aging children, aging self stuck in the middle.With her uniquely wry and funny admissions and insights, Guisewite unearths the humor and horror of everything from the mundane (trying to introduce her parents to TiVo and facing four decades' worth of unorganized photos) to the profound (finding a purpose post-retirement, helping parents downsize their lives, and declaring freedrom from all those things that hold us back). No longer confined to the limits of four comic panels, Guisewite holds out her hand in prose form and becomes a reassuring companion for those on the threshold of "what happens next." Heartfelt and humane and always cathartic, Fifty Things That Aren't My Fault is ideal reading for mothers, daughters, and anyone who is caught somewhere in between.

    At age twenty-four, Hornbacher was diagnosed with Type I rapid-cycle bipolar, the most severe form of bipolar disorder.In Madness, in her trademark wry and utterly self-revealing voice, Hornbacher tells her new story. Through scenes of astonishing visceral and emotional power, she takes us inside her own desperate attempts to counteract violently careening mood swings by self-starvation, substance abuse, numbing sex, and self-mutilation. How Hornbacher fights her way up from a madness that all but destroys her, and what it is like to live in a difficult and sometimes beautiful life and marriage -- where bipolar always beckons -- is at the center of this brave and heart-stopping memoir.Madness delivers the revelation that Hornbacher is not alone: millions of people in America today are struggling with a variety of disorders that may disguise their bipolar disease. And Hornbacher's fiercely self-aware portrait of her own bipolar as early as age four will powerfully change, too, the current debate on whether bipolar in children actually exists.Ten years after Kay Redfield Jamison's An Unquiet Mind, this storm of a memoir will revolutionize our understanding of bipolar disorder.

    Offering a frank and funny critique of the cultural forces that are driving us mad, Caroline Dooner examines how treating ourselves like never ending self-improvement projects is a recipe for burnout. We have become unknowingly complicit in perpetuating our own exhaustion because we are treating ourselves like machines. But even phones need to f*cking recharge.Caroline takes a good hard look at the dark side of self-help, and explains how she eventually used a radical period of rest to push back against cultural expectations and reclaim some peace.Tired As F*ck empowers us to say no to the things that exhaust us. It inspires us to carve out time to slow down, feel okay about doing less, and honor our humanity.This is not a self-help book, it's a cautionary tale. It's an honest look at the dogma of wellness and spiritual self-improvement culture and revels in the healing power of rest and letting shit go.

    A collective cry for help from a generation who have come of age entrenched in the culture of divorce, economic instability, and AIDS, here is the intensely personal story of a young girl full of promise, whose mood swings have risen and fallen like the lines of a sad ballad.

    In a series of candid, vulnerable, and wise essays that takes a closer look at what it means to love someone, be loved, and how we present our love to the world, Catron deconstructs her own personal canon of love stories. She delves all the way back to 1944, when her grandparents first met in a coal mining town in Appalachia, to her own dating life as a professor in Vancouver, drawing insights from her fascinating research into the universal psychology, biology, history, and literature of love. She uses biologists’ research into dopamine triggers to ask whether the need to love is an innate human drive. She uses literary theory to show why we prefer certain kinds of love stories. She urges us to question the unwritten scripts we follow in relationships and looks into where those scripts come from in the first place. And she tells the story of how she decided to test a psychology experiment that she’d read about—where the goal was to create intimacy between strangers using a list of thirty-six questions—and ended up in the surreal situation of having millions of people following her brand-new relationship. In How to Fall in Love with Anyone Catron flips the script on love and offers a deeply personal, and universal, investigation.

    But under the surface was a wild instability. The only child of parents continually battling drug and alcohol addictions, Madden confronted her environment alone. Facing a culture of assault and objectification, she found lifelines in the desperately loving friendships of fatherless girls.With unflinching honesty and lyrical prose, spanning from 1960s Hawai'i to the present-day struggle of a young woman mourning the loss of a father while unearthing truths that reframe her reality, Long Live the Tribe of Fatherless Girls is equal parts eulogy and love letter. It's a story about trauma and forgiveness, about families of blood and affinity, both lost and found, unmade and rebuilt, crooked and beautiful.

    Erin recounts everything from meeting her soulmate at age 14 to her first chemotherapy session at age 19 to what really goes on behind the scenes at a major Internet media company. She authentically captures the agony and the ecstasy of the millennial experience, whether it's her first kiss ("Sean's tongue! In my mouth! Slippery and wet like a slug in the rain.") or her struggles with anxiety ("When people throw caution to the wind, I am stuck imagining the poor soul who has to break his back sweeping caution into a dustpan"). Yet Erin also offers a fresh perspective on universal themes of resilience and love as she writes about surviving cancer, including learning of her mother's own cancer diagnosis within the same year, and her attempts to hide the diagnosis from friends to avoid "un-normaling" everything.

    Fans around the world are drawn to Her Grace’s voice, her wit, her life-affirming love for all humanity, and the fun and friendship of the community that’s sprung up around her.

    That is, until she found herself clinging to a stone statue of Joseph Stalin, newly beheaded by student protests.Communism had failed to deliver the promised utopia. One’s “biography”—class status and other associations long in the past—put strict boundaries around one’s individual future. When Lea’s parents spoke of relatives going to “university” or “graduating,” they were speaking of grave secrets Lea struggled to unveil. And when the early ’90s saw Albania and other Balkan countries exuberantly begin a transition to the “free market,” Western ideals of freedom delivered chaos: a dystopia of pyramid schemes, organized crime, and sex trafficking.With her elegant, intellectual, French-speaking grandmother; her radical-chic father; and her staunchly anti-socialist, Thatcherite mother to guide her through these disorienting times, Lea had a political education of the most colorful sort—here recounted with outstanding literary talent. Now one of the world’s most dynamic young political thinkers and a prominent leftist voice in the United Kingdom, Lea offers a fresh and invigorating perspective on the relation between the personal and the political, between values and identity, posing urgent questions about the cost of freedom.

    These beautifully rendered tales illuminate the fundamental pathways of life from birth to death.A woman finds herself daydreaming as she returns home from a business trip; a young man loses his wallet. We learn, too, from more extreme examples: the patient who points an unloaded gun at a police officer, the compulsive liar who convinces his wife he's dying of cancer. The stories invite compassionate understanding, suggesting answers to the questions that compel and disturb us most about love and loss, parents and children, work and change. The resulting journey will spark new ideas about who we are and why we do what we do.

    Michael Perry loves this place. He grew up here, and now -- after a decade away -- he has returned. Unable to polka or repair his own pickup, his farm-boy hands gone soft after years of writing, Mike figures the best way to regain his credibility is to join the volunteer fire department. Against a backdrop of fires and tangled wrecks, bar fights and smelt feeds, he tells a frequently comic tale leavened with moments of heartbreaking delicacy and searing tragedy.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.