But it was only when his own son-in the throes of a manic episode-broke into a neighbor's house that he learned what happens to mentally ill people who break a law. This is the Earley family's compelling story, a troubling look at bureaucratic apathy and the countless thousands who suffer confinement instead of care, brutal conditions instead of treatment, in the "revolving doors" between hospital and jail. With mass deinstitutionalization, large numbers of state mental patients are homeless or in jail-an experience little better than the horrors of a century ago. Earley takes us directly into that experience-and into that of a father and award-winning journalist trying to fight for a better way.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Doubtfire—as a brilliant new chronicler of the experience that is growing up young and female.   Mara Wilson has always felt a little young and a little out of place: as the only child on a film set full of adults, the first daughter in a house full of boys, the sole clinically depressed member of the cheerleading squad, a valley girl in New York and a neurotic in California, and one of the few former child actors who has never been in jail or rehab. Tackling everything from how she first learned about sex on the set of Melrose Place, to losing her mother at a young age, to getting her first kiss (or was it kisses?) on a celebrity canoe trip, to not being “cute” enough to make it in Hollywood, these essays tell the story of one young woman’s journey from accidental fame to relative (but happy) obscurity. But they also illuminate a universal struggle: learning to accept yourself, and figuring out who you are and where you belong. Exquisitely crafted, revelatory, and full of the crack comic timing that has made Mara Wilson a sought-after live storyteller and Twitter star, Where Am I Now? introduces a witty, perceptive, and refreshingly candid new literary voice.

    Hit with this devastating barrage, Tig took her grief onstage. Days after receiving her cancer diagnosis, she broke new comedic ground, opening an unvarnished set with the words, “Good evening. Hello. I have cancer. How are you? Hi, how are you? Is everybody having a good time? I have cancer.” Word of the set went viral instantly. This set was ultimately released as Tig’s sophomore album, Live, which sold 100,000 units in just six weeks and was nominated for a Grammy. Now, the wildly popular star takes stock of that no good, very bad year—a difficult yet astonishing period in which tragedy turned into absurdity and despair into joy. An inspired combination of the deadpan silliness of her comedy and the open-hearted vulnerability that has emerged in the wake of that dire time, Untitled is a moving and often hilarious look at this very brave, very funny woman’s journey through the darkness and her thrilling return.

    This is Tori's opportunity to define herself on her own terms.

    From her beginnings as a wunderkind producer of pirated stage productions for six-year-olds, through her spirited adventures watching self-satisfying monkeys, throwing up on Chinese food deliverymen, and stalking Leo DiCaprio, here are the goofy highs and horrifying lows of life as Kelly Oxford.

    And if other people can laugh at your awful shit as well, then I guess you can officially call yourself a comedian.In Boston, a college student fears leaving her own room—even to use the toilet. In Pennsylvania, a meek personal assistant finally confronts a perpetually enraged gay spiritual guru. In Texas, a rookie high school teacher deals with her male student’s unusually, er, hard personal problem. Sara Benincasa has been that terrified student, that embattled employee, that confused teacher—and so much more. Her hilarious memoir chronicles her attempts to forge a wonderfully weird adulthood in the midst of her lifelong struggle with agoraphobia, depression, and unruly hair.Relatable, unpretentious, and unsentimental, Agorafabulous! celebrates eccentricity, resilience, and the power of humor to light up even the darkest corners of our lives. (There are also some sexy parts, but they’re really awkward. Like really, really awkward.)

    Taking us back to her adolescence, when she was diagnosed with depression at fourteen, Kat speaks eloquently with pathos and humor about her skin picking, hand flapping, “nervousness” that made her the recipient of many a harsh taunt. With her mother also gripped by depression and health issues throughout her life, Kat came to live in a constant state of unease—that she would fail, that she would never find love . . . that she would end up just like her mother.Now, as a successful media personality, Kat still battles anxiety every day. That anxiety manifests in strange, and deeply personal ways. But as she found when she started to write about her struggles, Kat is not alone in feeling like the simple act of leaving the house, or getting a haircut can be crippling. And though periodic medication, counseling, a successful career and a happy marriage have brought her relief, the illness, because that is what anxiety is, remains.Exploring how millions are affected anxiety, Hi, Anxiety is a clarion call for everyone—but especially women—struggling with this condition. Though she is a strong advocate for seeking medical intervention, Kinsman implores those suffering to come out of the shadows—to talk about their battle openly and honestly. With humor, bravery, and writing that brings bestsellers like Laurie Notaro and Jenny Lawson to mind, Hi, Anxiety tackles a difficult subject with amazing grace.

     “A pleasure. Ellie Kemper is the kind of stable, intelligent, funny, healthy woman that usually only exists in yogurt commercials. But she’s real and she’s all ours!” —Tina Fey “Ellie is a hilarious and talented writer, although we’ll never know how much of this book the squirrel wrote.”—Mindy KalingMeet Ellie, the best-intentioned redhead next door. You’ll laugh right alongside her as she shares tales of her childhood in St. Louis, whether directing and also starring in her family holiday pageant, washing her dad’s car with a Brillo pad, failing to become friends with a plump squirrel in her backyard, eating her feelings while watching PG-13 movies, or becoming a “sports monster” who ends up warming the bench of her Division 1 field hockey team in college. You’ll learn how she found her comedic calling in the world of improv, became a wife, mother and New Yorker, and landed the role of a bridesmaid (while simultaneously being a bridesmaid) in Bridesmaids. You’ll get to know and love the comic, upbeat, perpetually polite actress playing Erin Hannon on The Office, and the exuberant, pink-pants-wearing star of Unbreakable Kimmy Schmidt. If you’ve ever been curious about what happens behind the scenes of your favorite shows, what it really takes to be a soul cycle “warrior,” how to recover if you accidentally fall on Doris Kearns Goodwin or tell Tina Fey on meeting her for the first time that she has “great hair—really strong and thick,” this is your chance to find out. But it’s also a laugh-out-loud primer on how to keep a positive outlook in a world gone mad and how not to give up on your dreams. Ellie “dives fully into each role—as actor, comedian, writer, and also wife and new mom—with an electric dedication, by which one learns to reframe the picture, and if not exactly become a glass-half-full sort of person, at least become able to appreciate them” (Vogue.com).

    A mother, wife, and working professional, Reiland was diagnosed with borderline personality disorder at the age of 29—a diagnosis that finally explained her explosive anger, manipulative behaviors, and self-destructive episodes including bouts of anorexia, substance abuse, and promiscuity. A truly riveting read with a hopeful message.

    In The Chronology of Water, Lidia Yuknavitch expertly moves the reader through issues of gender, sexuality, violence, and the family from the point of view of a lifelong swimmer turned artist. In writing that explores the nature of memoir itself, her story traces the effect of extreme grief on a young woman’s developing sexuality that some define as untraditional because of her attraction to both men and women. Her emergence as a writer evolves at the same time and takes the narrator on a journey of addiction, self-destruction, and ultimately survival that finally comes in the shape of love and motherhood.

    Wallace’s pieces for Harper’s magazine in the ’90s were, according to Lipsky, “like hearing for the first time the brain voice of everybody I knew: Here was how we all talked, experienced, thought. It was like smelling the damp in the air, seeing the first flash from a storm a mile away. You knew something gigantic was coming.”Then Rolling Stone sent Lipsky to join Wallace on the last leg of his book tour for Infinite Jest, the novel that made him internationally famous. They lose to each other at chess. They get iced-in at an airport. They dash to Chicago to catch a make-up flight. They endure a terrible reader’s escort in Minneapolis. Wallace does a reading, a signing, an NPR appearance. Wallace gives in and imbibes titanic amounts of hotel television (what he calls an “orgy of spectation”). They fly back to Illinois, drive home, walk Wallace’s dogs. Amid these everyday events, Wallace tells Lipsky remarkable things—everything he can about his life, how he feels, what he thinks, what terrifies and fascinates and confounds him—in the writing voice Lipsky had come to love. Lipsky took notes, stopped envying him, and came to feel about him—that grateful, awake feeling—the same way he felt about Infinite Jest. Then Lipsky heads to the airport, and Wallace goes to a dance at a Baptist church.A biography in five days, Although Of Course You End Up Becoming Yourself is David Foster Wallace as few experienced this great American writer. Told in his own words, here is Wallace’s own story, and his astonishing, humane, alert way of looking at the world; here are stories of being a young writer—of being young generally—trying to knit together your ideas of who you should be and who other people expect you to be, and of being young in March of 1996. And of what it was like to be with and—as he tells it—what it was like to become David Foster Wallace.

    The emotional, incredible true story of Neil White, a man who discovers the secret to happiness, leading a fulfilling life, and the importance of fatherhood in the most unlikely of places—the last leper colony in the continental United States.

    These observations are the source code for his finest work, and through them he has honed his cunning, surprising sentences.Now, Sedaris shares his private writings with the world. Theft by Finding, the first of two volumes, is the story of how a drug-abusing dropout with a weakness for the International House of Pancakes and a chronic inability to hold down a real job became one of the funniest people on the planet.Written with a sharp eye and ear for the bizarre, the beautiful, and the uncomfortable, and with a generosity of spirit that even a misanthropic sense of humor can't fully disguise, Theft By Finding proves that Sedaris is one of our great modern observers. It's a potent reminder that when you're as perceptive and curious as Sedaris, there's no such thing as a boring day.

    Mary Anne Schwalbe is waiting for her chemotherapy treatments when Will casually asks her what she's reading. The conversation they have grows into tradition: soon they are reading the same books so they can have something to talk about in the hospital waiting room. The ones they choose range from classic to popular, from fantastic to spiritual, and we hear their passion for reading and their love for each other in their intimate and searching discussions. A profoundly moving testament to the power of love between a child and parent, and the power of reading in our lives.