New Spotlight figures integrate brief text and visuals for easy reading. This package contains: Fundamentals of Anatomy & Physiology, Ninth Edition

    An x-ray microscope would do the trick, or since we're dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.

    It will make you angry. It will amaze you with the courage of some of the people described in the book...The Autoimmune Epidemic is every bit as compelling as Upton Sinclair's The Jungle...It is also every bit as necessary as An Inconvenient Truth.... You will leave this book with no reservations about the veracity of the conclusions: put simply, there is no doubt that autoimmune diseases are on the rise and increasing environmental exposures of toxins and chemicals is fueling this rise. The research is sound. The conclusions unassailable.... Reading The Autoimmune Epidemic is a necessary first step. Reading The Autoimmune Epidemic is a life-altering event. It needs to be."

    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    The award citation described the book as "Beautifully constructed with superb clarity of style - Davidson's continues to provide for students, doctors and other health professionals a sound basis for the practice of medicine."This internationally famous and best-selling textbook of general (or internal) medicine is renowned for providing a rational and easily understood basis for the practice of clinical medicine. Since it was first published this comprehensive text has met the requirements of several generations of medical students preparing for their examinations, while serving as a valuable reference for doctors in training. Rather than page after page of dense text, this reference makes finding information a snap by featuring lavish, colorful visual information. Extensive tables, crib boxes, MRI images, and x-ray films accompany each chapter's succinct discussions. The book's clear organization and color-coded chapters make it simple to find just the information you need, when you need it.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    Its aim is to explain the management of disease, based on an understanding of scientific principles and including the latest developments in treatment. It is written for medical students and doctors preparing for specialist exams, and is an ideal general reference text for all practising doctors. The new edition is part of Elsevier's new STUDENT CONSULT electronic community. STUDENT CONSULT titles comes with full text online, a unique image library, case studies, questions and answers, online note-taking, and integration links to content in other disciplines - ideal for problem-based learning.

    Includes tables to compare different agents within a given class of drugs. For use as a review for Boards, self-testing, or reference. Previous edition: c1997.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    Full of advice on how surgeons should use their heads as well as their hands - how to think, plan, and improvise - when, for example, operating on a massively bleeding trauma patient. Starts with general principles, continues with specific injuries to abdomen, chest, neck, and peripheral vessels. Generously illustrated throughout, with drawings produced specifically for this book. For residents, general surgeons with an interest in trauma, and for surgeons operating on badly wounded patients in isolated military, rural, or humanitarian settings. Asher Hirshberg and Kenneth L Mattox are trauma surgeons at the Ben Taub General Hospital, Houston, and professors at the Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, USA. Kenneth L Maddox is famous as the lead editor of McGraw Hill's classic text, Trauma, now in its fifth edition. This is going to be a GREAT book!

    The text covers the neuroanatomy that medical and other healthcare students need, with expanded coverage of neurophysiology and inclusion of clinical content providing real-life application of neuroanatomy and neurophysiologic concepts to clinical neurologic disorders. Its readability and enhanced full-color illustrations make it a favorite among both students and faculty.Provides a single-author approach for a more consistent, readable text.Contains summary statement headings to help you find what you're looking for within the text.Provides an outline introducing each chapter to help students organize and stay focused as they learn.Includes appealing four-color, computerized three-dimensional images of the brain and brain structures fully integrated with the text.Complements an Electronic Image Bank that is also available separately.Includes more coverage of neurobiology and neurophysiology.Gives more clinical content, including many images depicting neurologic disorders.Features an expanded section on higher cortical function.Features an expanded section on learning and memory.Contains a new chapter on the development, maintenance, and repair of neural connections-an explosive area of research in neuroscience.Supplies a glossary of key terms.Replaces many of the older figures with new, computer-generated illustrations.

    It discusses neuroanatomy, cell and molecular mechanisms and signaling through a cognitive approach to behaviour. It features an expanded treatment of the nervous system, neurological and psychiatric diseases and perception.

    It offers superior coverage of all key areas, including descriptive chemistry, MO theory, bonding, and physical inorganic chemistry. Chapter topics are presented in logical order and include: basic concepts; nuclear properties; an introduction to molecular symmetry; bonding in polyatomic molecules; structures and energetics of metallic and ionic solids; acids, bases, and ions in aqueous solution; reduction and oxidation; non-aqueous media; and hydrogen. Four special topic chapters, chosen for their currency and interest, conclude the book. For researchers seeking the latest information in the field of inorganic chemistry.