It offers complete coverage of the basics of hematologic morphology, including examination of the peripheral blood smear, basic maturation of the blood cell lines, and discussions of a variety of clinical disorders. Over 400 photomicrographs, schematic diagrams, and electron micrographs visually clarify hematology from normal cell maturation to the development of various pathologies.Normal Newborn Peripheral Blood Morphology chapter covers the unique normal cells found in neonatal blood.A variety of high-quality schematic diagrams, photomicrographs, and electron micrographs visually reinforce your understanding of hematologic cellular morphology.Spiral binding and compact size make this book easy to use in a laboratory setting.Coverage of common cytochemical stains, along with a summary chart for interpretation, aids in classifying malignant and benign leukoproliferative disorders.Morphologic abnormalities are presented in chapters on erythrocytes and leukocytes, along with a schematic description of each cell, to provide correlations to various disease states.Body Fluids chapter covers the other fluids found in the body besides blood, using images from cytocentrifuged specimens.Updated information on the subtypes of chronic lymphocytic leukemia (CLL) helps you recognize variant forms of CLL you may encounter in the lab.

    In " An Introduction to the Event-Related Potential Technique," Steve Luck offers the first comprehensive guide to the practicalities of conducting ERP experiments in cognitive neuroscience and related fields, including affective neuroscience and experimental psychopathology. The book can serve as a guide for the classroom or the laboratory and as a reference for researchers who do not conduct ERP studies themselves but need to understand and evaluate ERP experiments in the literature. It summarizes the accumulated body of ERP theory and practice, providing detailed, practical advice about how to design, conduct, and interpret ERP experiments, and presents the theoretical background needed to understand why an experiment is carried out in a particular way. Luck focuses on the most fundamental techniques, describing them as they are used in many of the world's leading ERP laboratories. These techniques reflect a long history of electrophysiological recordings and provide an excellent foundation for more advanced approaches.The book also provides advice on the key topic of how to design ERP experiments so that they will be useful in answering questions of broad scientific interest. This reflects the increasing proportion of ERP research that focuses on these broader questions rather than the "ERPology" of early studies, which concentrated primarily on ERP components and methods. Topics covered include the neural origins of ERPs, signal averaging, artifact rejection and correction, filtering, measurement and analysis, localization, and the practicalities of setting up the lab.

    When we are awake we identify with our body, but if we let our mind wander or daydream, we project a mentally imagined self into the remembered past or anticipated future. As we fall asleep, the impression of being a bounded self distinct from the world dissolves, but the self reappears in the dream state. If we have a lucid dream, we no longer identify only with the self within the dream. Our sense of self now includes our dreaming self, the "I" as dreamer. Finally, as we meditate--either in the waking state or in a lucid dream--we can observe whatever images or thoughts arise and how we tend to identify with them as "me." We can also experience sheer awareness itself, distinct from the changing contents that make up our image of the self.Contemplative traditions say that we can learn to let go of the self, so that when we die we can witness its dissolution with equanimity. Thompson weaves together neuroscience, philosophy, and personal narrative to depict these transformations, adding uncommon depth to life's profound questions. Contemplative experience comes to illuminate scientific findings, and scientific evidence enriches the vast knowledge acquired by contemplatives.

    Ratey provides insight into the basic structure and chemistry of the brain, and demonstrates how its systems shape our perceptions, emotions, and behavior. By giving us a greater understanding of how the brain responds to the guidance of its user, he provides us with knowledge that can enable us to improve our lives.In A User’s Guide to the Brain, Ratey clearly and succinctly surveys what scientists now know about the brain and how we use it. He looks at the brain as a malleable organ capable of improvement and change, like any muscle, and examines the way specific motor functions might be applied to overcome neural disorders ranging from everyday shyness to autism. Drawing on examples from his practice and from everyday life, Ratey illustrates that the most important lesson we can learn about our brains is how to use them to their maximum potential.

    Some philosophers argue that consciousness is something extra, beyond the physical workings of the brain. Others think that if we persist in our standard scientific methods, our questions about consciousness will eventually be answered. And some even suggest that the mystery is so deep, it will never be solved. Decades have been spent trying to explain consciousness from within our current scientific paradigm, but little progress has been made.Now, Philip Goff offers an exciting alternative that could pave the way forward. Rooted in an analysis of the philosophical underpinnings of modern science and based on the early twentieth-century work of Arthur Eddington and Bertrand Russell, Goff makes the case for panpsychism, a theory which posits that consciousness is not confined to biological entities but is a fundamental feature of all physical matter--from subatomic particles to the human brain. In Galileo's Error, he has provided the first step on a new path to the final theory of human consciousness.

    I also hope that it will serve as a useful reference too for the many workers engaged in one type of solid state research activity or another, who may be without formal training in the subject.

    In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.

    This updated edition features new material.

    Now in paperback, Dr Jeffrey Schwartz and Sharon Begley's groundbreaking work, The Mind and the Brain, argues exactly the opposite: that the mind has a life of its own.Dr Schwartz, a leading researcher in brain dysfunctions, and Wall Street Journal science columnist Sharon Begley demonstrate that the human mind is an independent entity that can shape and control the functioning of the physical brain. Their work has its basis in our emerging understanding of adult neuroplasticity–the brain's ability to be rewired not just in childhood, but throughout life, a trait only recently established by neuroscientists.Through decades of work treating patients with obsessive–compulsive disorder (OCD), Schwartz made an extraordinary finding: while following the therapy he developed, his patients were effecting significant and lasting changes in their own neural pathways. It was a scientific first: by actively focusing their attention away from negative behaviors and toward more positive ones, Schwartz's patients were using their minds to reshape their brains–and discovering a thrilling new dimension to the concept of neuroplasticity.The Mind and the Brain follows Schwartz as he investigates this newly discovered power, which he calls self–directed neuroplasticity or, more simply, mental force. It describes his work with noted physicist Henry Stapp and connects the concept of 'mental force' with the ancient practice of mindfulness in Buddhist tradition. And it points to potential new applications that could transform the treatment of almost every variety of neurological dysfunction, from dyslexia to stroke–and could lead to new strategies to help us harness our mental powers. Yet as wondrous as these implications are, perhaps even more important is the philosophical dimension of Schwartz's work. For the existence of mental force offers convincing scientific evidence of human free will, and thus of man's inherent capacity for moral choice.

    The mind is designed to often delude us, he argued, about ourselves and about the world. And it is designed to make happiness hard to sustain. But if we know our minds are rigged for anxiety, depression, anger, and greed, what do we do? Wright locates the answer in Buddhism, which figured out thousands of years ago what scientists are only discovering now. Buddhism holds that human suffering is a result of not seeing the world clearly—and proposes that seeing the world more clearly, through meditation, will make us better, happier people. In Why Buddhism is True, Wright leads readers on a journey through psychology, philosophy, and a great many silent retreats to show how and why meditation can serve as the foundation for a spiritual life in a secular age. At once excitingly ambitious and wittily accessible, this is the first book to combine evolutionary psychology with cutting-edge neuroscience to defend the radical claims at the heart of Buddhist philosophy. With bracing honesty and fierce wisdom, it will persuade you not just that Buddhism is true—which is to say, a way out of our delusion—but that it can ultimately save us from ourselves, as individuals and as a species.

    Unlike traditional empirical psychology, it is more oriented toward the how than the what. An experiment in mind design is more likely to be an attempt to build something and make it work--as in artificial intelligence--than to observe or analyze what already exists. Mind design is psychology by reverse engineering.When Mind Design was first published in 1981, it became a classic in the then-nascent fields of cognitive science and AI. This second edition retains four landmark essays from the first, adding to them one earlier milestone (Turing's Computing Machinery and Intelligence) and eleven more recent articles about connectionism, dynamical systems, and symbolic versus nonsymbolic models. The contributors are divided about evenly between philosophers and scientists. Yet all are philosophical in that they address fundamental issues and concepts; and all are scientific in that they are technically sophisticated and concerned with concrete empirical research.ContributorsRodney A. Brooks, Paul M. Churchland, Andy Clark, Daniel C. Dennett, Hubert L. Dreyfus, Jerry A. Fodor, Joseph Garon, John Haugeland, Marvin Minsky, Allen Newell, Zenon W. Pylyshyn, William Ramsey, Jay F. Rosenberg, David E. Rumelhart, John R. Searle, Herbert A. Simon, Paul Smolensky, Stephen Stich, A.M. Turing, Timothy van Gelder

    He followed his head over his gut and Karina was left permanently paralysed, altering both patient and surgeon's lives for ever. This decision would haunt Rahul for decades, a constant reminder of the fine line between saving and damaging a life.As one of the world's leading brain surgeons, Rahul is the last hope for patients with extreme forms of cancer. In treating them, he has observed humanity at its most raw and most robust. He has journeyed to unimaginable extremes with them, guiding them through the darkest moments of their lives.Life on a Knife's Edge is Rahul's beautifully written account of the resilience, courage and belief he has witnessed in his patients, and the lessons about human nature he has learned from them. It is about the impossible choices he has to make, and the fateful consequences he is forced to live with.From challenging the ethics of surgical practices, to helping a patient with locked-in syndrome communicate her dying wish to her family, Rahul shares his extraordinary experiences, revealing the depths of a surgeon's psyche that is continuously pushed to its limits.

    Simply put, beliefs come first and explanations for beliefs follow. The brain, Shermer argues, is a belief engine. From sensory data flowing in through the senses, the brain naturally begins to look for and find patterns, and then infuses those patterns with meaning. Our brains connect the dots of our world into meaningful patterns that explain why things happen, and these patterns become beliefs. Once beliefs are formed the brain begins to look for and find confirmatory evidence in support of those beliefs, which accelerates the process of reinforcing them, and round and round the process goes in a positive-feedback loop of belief confirmation. Shermer outlines the numerous cognitive tools our brains engage to reinforce our beliefs as truths.Interlaced with his theory of belief, Shermer provides countless real-world examples of how this process operates, from politics, economics, and religion to conspiracy theories, the supernatural, and the paranormal. Ultimately, he demonstrates why science is the best tool ever devised to determine whether or not a belief matches reality.

    Ryle's linguistic analysis remaps the conceptual geography of mind, not so much solving traditional philosophical problems as dissolving them into the mere consequences of misguided language. His plain language and esstentially simple purpose place him in the traditioin of Locke, Berkeley, Mill, and Russell.