With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Our governments are corrupt and the opposing parties pointlessly similar. Our culture is filled with vacuity and pap, and we are told there’s nothing we can do: “It’s just the way things are.”   In this book, Russell Brand hilariously lacerates the straw men and paper tigers of our conformist times and presents, with the help of experts as diverse as Thomas Piketty and George Orwell, a vision for a fairer, sexier society that’s fun and inclusive.   You have been lied to, told there’s no alternative, no choice, and that you don’t deserve any better. Brand destroys this illusory facade as amusingly and deftly as he annihilates Morning Joe anchors, Fox News fascists, and BBC stalwarts.   This book makes revolution not only possible but inevitable and fun.

    MacLeod and her husband encountered their dream while vacationing on a remote island in the Scottish Hebrides. Enthralled by its windswept beauty, they soon were the proud owners of a near-derelict croft house--a farmer's stone cottage--on "a small acre" of land. Mary assumed duties as the island's district nurse. Call the Nurse is her account of the enchanted years she and her family spent there, coming to know its folk as both patients and friends.In anecdotes that are by turns funny, sad, moving, and tragic, she recalls them all, the crofters and their laird, the boatmen and tradesmen, young lovers and forbidding churchmen. Against the old-fashioned island culture and the grandeur of mountain and sea unfold indelible stories: a young woman carried through snow for airlift to the hospital; a rescue by boat; the marriage of a gentle giant and the island beauty; a ghostly encounter; the shocking discovery of a woman in chains; the flames of a heather fire at night; an unexploded bomb from World War II; and the joyful, tipsy celebration of a ceilidh. Gaelic fortitude meets a nurse's compassion in these wonderful true stories from rural Scotland.

    It was the pain from that, from feeling ugly, that I always viewed as the great tragedy of my life. The fact that I had cancer seemed minor in comparison.At age nine, Lucy Grealy was diagnosed with a potentially terminal cancer. When she returned to school with a third of her jaw removed, she faced the cruel taunts of classmates. In this strikingly candid memoir, Grealy tells her story of great suffering and remarkable strength without sentimentality and with considerable wit. Vividly portraying the pain of peer rejection and the guilty pleasures of wanting to be special, Grealy captures with unique insight what it is like as a child and young adult to be torn between two warring impulses: to feel that more than anything else we want to be loved for who we are, while wishing desperately and secretly to be perfect.

     Michael Oher is the young man at the center of the true story depicted in "The Blind Side" movie (and book) that swept up awards and accolades. Though the odds were heavily stacked against him, Michael had a burning desire deep within his soul to break out of the Memphis inner-city ghetto and into a world of opportunity. While many people are now familiar with Oher's amazing journey, this is the first time he shares his account of his story in his own words, revealing his thoughts and feelings with details that only he knows, and offering his point of view on how anyone can achieve a better life. Looking back on how he went from being a homeless child in Memphis to playing in the NFL, Michael talks about the goals he had for himself in order to break out of the cycle of poverty, addiction, and hopelessness that trapped his family for so long. He recounts poignant stories growing up in the projects and running from child services and foster care over and over again in search of some familiarity. Eventually he grasped onto football as his ticket out of the madness and worked hard to make his dream into a reality. But Oher also knew he would not be successful alone. With his adoptive family, the Touhys, and other influential people in mind, he describes the absolute necessity of seeking out positive role models and good friends who share the same values to achieve one's dreams. Sharing untold stories of heartache, determination, courage, and love, "I Beat the Odds" is an incredibly rousing tale of one young man's quest to achieve the American dream.

    It is a poignant observation about the relationship between Mira, her sister, and their mentally ill mother. Before she was struck with schizophrenia at the age of nineteen, beautiful piano protégé Norma Herr had been the most vibrant personality in the room. She loved her daughters and did her best to raise them well, but as her mental state deteriorated, Norma spoke less about Chopin and more about Nazis and her fear that her daughters would be kidnapped, murdered, or raped. When the girls left for college, the harassment escalated--Norma called them obsessively, appeared at their apartments or jobs, threatened to kill herself if they did not return home. After a traumatic encounter, Mira and her sister were left with no choice but to change their names and sever all contact with Norma in order to stay safe. But while Mira pursued her career as an artist--exploring the ancient romance of Florence, the eerie mysticism of northern Norway, and the raw desert of Israel--the haunting memories of her mother were never far away. Then one day, Mira’s life changed forever after a debilitating car accident. As she struggled to recover from a traumatic brain injury, she was confronted with a need to recontextualize her life--she had to relearn how to paint, read, and interact with the outside world. In her search for a way back to her lost self, Mira reached out to the homeless shelter where she believed her mother was living and discovered that Norma was dying. Mira and her sister traveled to Cleveland, where they shared an extraordinary reconciliation with their mother that none of them had thought possible. At the hospital, Mira discovered a set of keys that opened a storage unit Norma had been keeping for seventeen years. Filled with family photos, childhood toys, and ephemera from Norma’s life, the storage unit brought back a flood of previous memories that Mira had thought were lost to her forever. The Memory Palace is a breathtaking literary memoir about the complex meaning of love, truth, and the capacity for forgiveness among family. Through stunning prose and original art created by the author in tandem with the text, The Memory Palace explores the connections between mother and daughter that cannot be broken no matter how much exists--or is lost--between them.

    Most significant, aside from the grueling physical ordeal she underwent, was the way it changed how she felt inside and what she thought she ought to be doing with her days. Now she has written the book that she needed to read then. In this honest, wise, and upbeat guide, Alice Hoffman provides a road map for the making of one's life into the very best it can be. As she says, "In many ways I wrote this book to remind myself of the beauty of life, something that's all too easy to overlook during the crisis of illness or loss. There were many times when I forgot about roses and starry nights. I forgot that our lives are made up of equal parts sorrow and joy, and that it's impossible to have one without the other. . . . I wrote to remind myself that in the darkest hour the roses still bloom, the stars still come out at night. And to remind myself that, despite everything that was happening to me, there were still some choices I could make.

    He lifts the lid on government targets that led to poor patient care. He reveals the level of alcohol-related injuries that often bring the service to a near standstill. He shows just how bloody hard it is to look after the people who turn up at the hospital door.But he also shares the funny side - the unusual ‘accidents’ that result in with weird objects inserted in places they really should have ended up - and also the moving, tragic and heartbreaking.It really is an unforgettable read.

    In this absorbing, surprising, and undeniably compelling book, forensics expert Emily Craig tells her own story of a life spent teasing secrets from the dead.Emily Craig has been a witness to history, helping to seek justice for thousands of murder victims, both famous and unknown. It's a personal story that you won't soon forget.Emily first became intrigued by forensics work when, as a respected medical illustrator, she was called in by the local police to create a model of a murder victim's face. Her fascination with that case led to a dramatic midlife career change: She would go back to school to become a forensic anthropologist——and one of the most respected and best-known "bone hunters" in the nation.As a student working with the FBI in Waco, Emily helped uncover definitive proof that many of the Branch Davidians had been shot to death before the fire, including their leader, David Koresh, whose bullet-pierced skull she reconstructed with her own hands. Upon graduation, Emily landed a prestigious full-time job as forensic anthropologist for the Commonwealth of Kentucky, a state with an alarmingly high murder rate and thousands of square miles of rural backcountry, where bodies are dumped and discovered on a regular basis. But even with her work there, Emily has been regularly called to investigations across the country, including the site of terrorist attack on the the Murrah Building in Oklahoma City, where a mysterious body part——a dismembered leg——was found at the scene and did not match any of the known victims. Through careful scientific analysis, Emily was able to help identify the leg's owner, a pivotal piece of evidence that helped convict Timothy McVeigh.In September 2001, Emily recieved a phone call summoning her to New York City, where she directed the night-shift triage at the World Trade Centre's body identification site, collaborating with forensics experts from all over the country to collect and identify the remains of September 11 victims.From the biggest new stories of our time to stranger-than-true local mysteries, these are unforgettable stories from the case files of Emily Craig's remarkable career.

    Lara, a superstar nurse who tries to battle her way back from a near-ruinous prescription-drug addiction. The outspoken but compassionate Juliette, a fierce advocate for her patients. And Sam, a first-year nurse, struggling to find her way in a gossipy mean-girl climate she likens to “high school, except for the dying people.”The result is a riveting page-turner, insightful and thought-provoking, that will leave readers feeling smarter about their healthcare and undeniably appreciative of the incredible nurses who provide it.

    Breast cancer. In an instant, her life changed all because of a single word she couldn’t even bring herself to say out loud. The ugly C word.Share in the journey of one young woman’s fight against breast cancer, the sacrifices a family makes, the heartbreak cancer leaves in its path, and the joy found along the way.

    Vincent DiMaio and veteran crime writer Ron Franscell guide us behind the morgue doors to tell a fascinating life story through the cases that have made Di Maio famous-from the exhumation of assassin Lee Harvey Oswald to the complex issues in the shooting of Florida teenager Trayvon Martin.Beginning with his street-smart Italian origins in Brooklyn, the book spans 40 years of work and more than 9,000 autopsies, and Di Maio's eventual rise into the pantheon of forensic scientists. One of the country's most methodical and intuitive criminal pathologists will dissect himself, maintaining a nearly continuous flow of suspenseful stories, revealing anecdotes, and enough macabre insider details to rivet the most fervent crime fans.

    Born with the rare genetic condition progeria, she ages eight times faster than the average person. In medical terms her body is like that of a 100-year-old woman. Yet she faces her condition with immense courage and a refreshing lack of self-pity. In Old Before My Time, Hayley and her mum Kerry reflect on her unusual life. Share Hayley's excitement as she travels the world meeting her pop heroes Kylie, Girls Aloud and Justin Bieber and her sadness as she loses her best friend to the disease at the age of 11. Now as she passes the age of 13 -- the average life expectancy for a child with progeria -- Hayley talks frankly about her hopes for the future and her pioneering drug trials in America which could unlock the secrets of ageing for everyone...

    The name alone conjures images of chestnut-lined boulevards, sidewalk cafés, breathtaking façades around every corner--in short, an exquisite romanticism that has captured the American imagination for as long as there have been Americans.In 1995, Adam Gopnik, his wife, and their infant son left the familiar comforts and hassles of New York City for the urbane glamour of the City of Light. Gopnik is a longtime New Yorker writer, and the magazine has sent its writers to Paris for decades--but his was above all a personal pilgrimage to the place that had for so long been the undisputed capital of everything cultural and beautiful. It was also the opportunity to raise a child who would know what it was to romp in the Luxembourg Gardens, to enjoy a croque monsieur in a Left Bank café--a child (and perhaps a father, too) who would have a grasp of that Parisian sense of style we Americans find so elusive.So, in the grand tradition of the American abroad, Gopnik walked the paths of the Tuileries, enjoyed philosophical discussions at his local bistro, wrote as violet twilight fell on the arrondissements. Of course, as readers of Gopnik's beloved and award-winning "Paris Journals" in The New Yorker know, there was also the matter of raising a child and carrying on with day-to-day, not-so-fabled life. Evenings with French intellectuals preceded middle-of-the-night baby feedings; afternoons were filled with trips to the Musée d'Orsay and pinball games; weekday leftovers were eaten while three-star chefs debated a "culinary crisis."As Gopnik describes in this funny and tender book, the dual processes of navigating a foreign city and becoming a parent are not completely dissimilar journeys--both hold new routines, new languages, a new set of rules by which everyday life is lived. With singular wit and insight, Gopnik weaves the magical with the mundane in a wholly delightful, often hilarious look at what it was to be an American family man in Paris at the end of the twentieth century. "We went to Paris for a sentimental reeducation - I did anyway - even though the sentiments we were instructed in were not the ones we were expecting to learn, which I believe is why they call it an education."

    But through self-discipline, mental toughness, and hard work, Goggins transformed himself from a depressed, overweight young man with no future into a U.S. Armed Forces icon and one of the world's top endurance athletes. The only man in history to complete elite training as a Navy SEAL, Army Ranger, and Air Force Tactical Air Controller, he went on to set records in numerous endurance events, inspiring Outside magazine to name him "The Fittest (Real) Man in America."In Can't Hurt Me, he shares his astonishing life story and reveals that most of us tap into only 40% of our capabilities. Goggins calls this The 40% Rule, and his story illuminates a path that anyone can follow to push past pain, demolish fear, and reach their full potential.