Millennia ago, when we first began puzzling over the mysteries of the human body, one organ stood out as vital. The heart was warm, it was central, and it moved as it pumped blood. The ancient Egyptians treated it with reverence, mummifying it separately from the body so that the soul inside it could be weighed. Aristotle believed that it was the seat of consciousness. Over the centuries, science has dispelled the myths, but our fascination with the heart has endured.     From the origins of circulation, still evident in some microorganisms today, to the enormous hearts of blue whales, we journey with Bill to beaches where horseshoe crabs are being harvested for their life-saving blood, and under the sea to learn about the world’s most natural antifreeze, flowing through the veins of icefish. And we follow him through human history, too, as scientists hypothesize wrongly and rightly about what is arguably our most important organ, ultimately developing the technologies that have helped us study the heart—and now, in the most cutting-edge labs, the tools that will help us regenerate it.   Deeply researched and engagingly told, Pump is a fascinating natural history sure to be loved by readers of Mary Roach and Bill Bryson.

    Those who knew him well would never have imagined that, as a young man, he’d be adrift with few prospects and plotting to rob a bank. But he did, committing five armed bank robberies before being apprehended. Serving ten years in federal prison, Shon feared his life was over. He wasn’t sure if he could survive a cell block, but he was determined to try. Hopwood pumped-up in the prison gym to defend himself and earned respect on the basketball court. He reconnected with the girl of his dreams from high school through letters and prison visits; and, crucially, he talked his way into a job in the prison law library. Hopwood slowly taught himself criminal law and began to help fellow inmates rather than himself. He wrote one petition to the Supreme Court, which was chosen to be heard from over 7,000 other petitions submitted by the greater legal community that year. The Justices voted 9-0 in favor of Hopwood’s petition when the case was finally heard. What might have been considered luck by some, was dispelled when a second petition from him was selected to be heard by the Supreme Court. He didn’t grasp it yet, but Shon’s legal work was the start of a new life. Shon works on policy reform, and he is a cofounder of PrisonProfessors.com. He strives to improve outcomes of America’s prison system, and he tells his amazing story in Law Man.

    The alimentary canal is classic Mary Roach terrain: the questions explored in Gulp are as taboo, in their way, as the cadavers in Stiff and every bit as surreal as the universe of zero gravity explored in Packing for Mars. Why is crunchy food so appealing? Why is it so hard to find words for flavors and smells? Why doesn’t the stomach digest itself? How much can you eat before your stomach bursts? Can constipation kill you? Did it kill Elvis? In Gulp we meet scientists who tackle the questions no one else thinks of—or has the courage to ask. We go on location to a pet-food taste-test lab, a fecal transplant, and into a live stomach to observe the fate of a meal. With Roach at our side, we travel the world, meeting murderers and mad scientists, Eskimos and exorcists (who have occasionally administered holy water rectally), rabbis and terrorists—who, it turns out, for practical reasons do not conceal bombs in their digestive tracts.Like all of Roach’s books, Gulp is as much about human beings as it is about human bodies.

    But by this point in her startling book, Dangerous Doses, readers are already on a first-name basis with the five investigators involved in breaking the case. These five -- drug inspectors, Miami detectives, and a former cop -- had marshaled their forces to protect Floridians from adulterated, expired, or mishandled prescription drugs, and Eban spent two and a half years with them, weaving together her story of drug supply corruption, not merely in Florida but throughout the nation.Americans spend nearly $216 billion to fill over 3 billion prescriptions a year, and most believe that what they ingest, inject, or apply topically travels from the drug maker to their pharmacy through pristine labs and warehouses filled with men in white coats. But Eban discovered a different route, one driven by middlemen: wholesalers who sell diverted, degraded, and expired medicine traded by felons and accompanied by falsified paperwork. The truth is chilling and complex, but Eban's intelligent writing, careful plotting, and dogged reporting make for a suspenseful and shocking read, and she offers a battle-ready road map for combating the problem, including excellent practical advice for consumers. (Fall 2005 Selection)

    But now, with revolutionary medical advances, death has become just another serious complication. As a young medical student, Dr. David Casarett was inspired by the story of a two-year-old girl named Michelle Funk. Michelle fell into a creek and was underwater for over an hour. When she was found she wasn’t breathing, and her pupils were fixed and dilated. That drowning should have been fatal. But after three hours of persistent work, a team of doctors and nurses was able to bring her back. It was a miracle. If Michelle could come back after three hours of being dead, what about twelve hours? Or twenty-four? What would it take to revive someone who had been frozen for one thousand years? And what does blurring the line between “life” and “death” mean for society? In Shocked, Casarett chronicles his exploration of the cutting edge of resuscitation and reveals just how far science has come. He begins in the eighteenth century, when early attempts at resuscitation involved public displays of barrel rolling, horseback riding (sort of), and blowing smoke up the patient’s various orifices. He then takes us inside a sophisticated cryonics facility in the Arizona desert, a darkroom full of hibernating lemurs in North Carolina, and a laboratory that puts mice into a state of suspended animation. The result is a spectacular tour of the bizarre world of doctors, engineers, animal biologists, and cryogenics enthusiasts trying to bring the recently dead back to life. Fascinating, thought-provoking, and (believe it or not) funny, Shocked is perfect for those looking for a prequel—and a sequel—to Mary Roach’s Stiff, or for anyone who likes to ponder the ultimate questions of life and death.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    Bill Rawls understands Lyme disease sufferers seeking clarity and relief because, like myself, he has experienced the pain and frustration firsthand. Through this ground-breaking book, he shares everything he has discovered on his journey to reclaiming his health... it may just be the answer you've been waiting for." – Neil Spector, MD, Author of Gone in a Heartbeat Lyme disease is one of the most puzzling illnesses on the planet. Anyone who has suffered from its debilitating symptoms knows the frustrations of trying to find a cure. Many sufferers drag themselves from one doctor or alternative practitioner to the next, getting lost in a maze of lab tests, prescription drugs, and treatments. Thousands of dollars and months (or years) later, they realize they are no better off than where they started. Unlocking Lyme puts an end to this desperate quest. Written by Dr. Bill Rawls, a physician who overcame Lyme disease himself, this book is a comprehensive, practical resource full of solutions that work. What took Dr. Rawls 10 years to learn through intense research and personal experience, you can now learn and implement in a matter of months. DR. RAWLS’ STORY Dr. Rawls was in the middle of a successful OB/GYN career when Lyme disease interrupted his life. In his struggle to overcome it, he explored every treatment option – from conventional medicine to the full range of alternative therapies. Ultimately, he embraced modern herbal therapy as his preferred solution, but he recognizes that the path may be different for each person. INSIDE THE BOOK Unlocking Lyme is the sum of Dr. Rawls’ experience, research, and practical solutions to date. The book is divided into four parts, each part addressing a critical aspect of recovery: PART 1 - Provides an overview of common misconceptions about what Lyme disease is (hint: it’s more than just a tick bite and Borrelia infection) PART 2 - Provides information on how to obtain a diagnosis, despite current limitations in diagnostic testing for Lyme PART 3 - Discusses limitations of long-term antibiotic use, and offers an overview of holistic and non-toxic therapies for healing and symptom control (including pain, depression, insomnia) PART 4 - Explains how to embrace a healthier lifestyle so you can stay well; learn how to strengthen your immune system, microbiome, and balance in your body In the years since his recovery, Dr. Rawls has helped thousands of patients find their path to healing from Lyme disease. Unlocking Lyme brings together Dr. Rawls’ accumulated knowledge and is the key you need to get your life back. TESTIMONIALS “Dr. Rawls understands the misery of chronic Lyme disease firsthand. Unlocking Lyme shares the approaches that he used to successfully recover his own health, and helps the reader understand that there is so much that can be done to regain a state of wellness and optimal health.” – Scott Forsgren Editor & Founder, BetterHealthGuy.com “Dr. Rawls has spoken on his approach to Lyme disease for the past several years; his comprehensive approach and lifestyle guidance has helped many of our members. We heartily endorse his approach to helping deal with the symptoms of Lyme and other tick-borne illnesses.” – John Dorney, President NC Lyme Disease Foundation "Unlocking Lyme delves into the science behind Lyme disease, explaining what it is, but more importantly how it can be overcome. Dr. Rawls carefully explains the various treatments for Lyme, leaving the reader feeling informed and empowered.

     In the vein of In Cold Blood, Closing Time is the stunning story of good and evil colliding in the most tragic of ways, both for the victims and their loved ones left behind to re-live their horror. Kenneth Staton was the well-respected owner of a jewelry store in Van Buren, Arkansas. Although crippled with rheumatoid arthritis and unable to walk without crutches, he had built his business through excellent watch repair work, fine quality jewelry sold at fair prices, and a dedication to his customers that surpassed all other merchants. He was the quintessential gentleman in all aspects of his life, and a beloved father. Unknown to him, two men—a seasoned criminal with a propensity for violence and a younger man, handsome, but broke and with an obsessive thirst for alcohol—plotted to rob the jewelry store at closing time on September 10, 1980. The thugs had only met each other days before, and it was the younger one's first venture into armed robbery. When Staton and his daughter Suzanne didn't show up for supper, his other two daughters became alarmed and went to the store. There they found the bodies of their father and youngest sister lying in pools of blood, gagged, hogtied, and shot twice in the head. Close to $100,000 dollars in diamonds and other jewelry had been stolen. This senseless, bloody crime rocked the town of Van Buren and set its lawmen, sworn to find the killers, on a fiercely determined hunt that led from Rogers, Arkansas to Jacksonville, Florida, and all the way to Vancouver, Canada. Seventeen years later, was justice served? Praise for Closing Time “Anita Paddock is the newest and strongest voice in true crime writing. Closing Time makes you feel as if you are there, seeing what happened, and feeling the terror and sorrow of those felled by these brutal crimes.” – Marla Cantrell, Editor of Do South Magazine and an Arkansas Art Council Fellow “Anita Paddock delivers again. Closing Time reveals an unvarnished truth that will, at times, leave her readers breathless. Those familiar with her work will quickly conclude that Closing Time is a worthy successor to her previous best seller, Blind Rage. Get ready for some late nights because you won’t be able to put this one down.” – Greg Shepard, author of Earthstains, the story of Matt and George Kimes who came of age in the Roaring Twenties with a string of sensational bank robberies.

    Dairy products don't strengthen bones. Drugs may be dangerous.For years, doctors have been telling us to drink milk, eat dairy products, and take calcium pills to improve our bone vitality. The problem is, they're wrong. This groundbreaking guide uses the latest clinical studies and the most up-to-date medical information to help you strengthen your bones, reduce the risk of fractures, and prevent osteoporosis. You'll learn why there's no proof of calcium's effectiveness, despite what doctors say, and why a low-acid diet is the only effective way to prevent bone loss."This clear, convincing explanation of osteoporosis will change the way the world thinks about bone health. Lanou and Castleman prove beyond doubt that milk and dairy are the problem, not the solution." -Rory Freedman, coauthor of #1 New York Times best seller Skinny Bitch"The authors have tackled an almost intractable myth: that calcium is the one and only key to bone vitality. It isn't. Everyone who cares about preventing osteoporosis should read this book." -- Dr. T. Colin Campbell, author of The China Study

    They want to make others think that they are sick. And they do this for one reason: money. Did you know: * Pharmaceutical companies invest more than 35,000 Euro (over $50,000) per physician each year to get them to prescribe their products? * More than 75 percent of leading scientists in the field of medicine are "paid for" by the pharmaceutical industry? * Corruption prevailed in the approval and marketing of drugs in some cases? * Illnesses are made up by the pharmaceutical industry and specifically marketed to enhance sales and market shares for the companies in question? * Pharmaceutical companies increasingly target children? "Side Effects: Death" is the true story of corruption, bribery and fraud written by Dr. John Virapen, who has been called THE Big Pharma Insider. During his 35 years in the pharmaceutical industry internationally (most notably as general manager of Eli Lilly and Company in Sweden), Virapen was responsible for the marketing of several drugs, all of them with side effects. Now, Virapen is coming clean and telling all of the little secrets you were never intended to know! For more information, go to www.sideeffectsdeath.com

    It governs the lives of microorganisms and galaxies; it shapes the capabilities of our extraordinarily large brains and the fortunes of our economies. Growth is manifested in annual increments of continental crust, a rising gross domestic product, a child's growth chart, the spread of cancerous cells. In this magisterial book, Vaclav Smil offers systematic investigation of growth in nature and society, from tiny organisms to the trajectories of empires and civilizations.Smil takes readers from bacterial invasions through animal metabolisms to megacities and the global economy. He begins with organisms whose mature sizes range from microscopic to enormous, looking at disease-causing microbes, the cultivation of staple crops, and human growth from infancy to adulthood. He examines the growth of energy conversions and man-made objects that enable economic activities—developments that have been essential to civilization. Finally, he looks at growth in complex systems, beginning with the growth of human populations and proceeding to the growth of cities. He considers the challenges of tracing the growth of empires and civilizations, explaining that we can chart the growth of organisms across individual and evolutionary time, but that the progress of societies and economies, not so linear, encompasses both decline and renewal. The trajectory of modern civilization, driven by competing imperatives of material growth and biospheric limits, Smil tells us, remains uncertain.

    

    Can our world support that? What kind of world will it be? Those answering these questions generally fall into two deeply divided groups--Wizards and Prophets, as Charles Mann calls them in this balanced, authoritative, nonpolemical new book. The Prophets, he explains, follow William Vogt, a founding environmentalist who believed that in using more than our planet has to give, our prosperity will lead us to ruin. Cut back! was his mantra. Otherwise everyone will lose! The Wizards are the heirs of Norman Borlaug, whose research, in effect, wrangled the world in service to our species to produce modern high-yield crops that then saved millions from starvation. Innovate! was Borlaug's cry. Only in that way can everyone win! Mann delves into these diverging viewpoints to assess the four great challenges humanity faces--food, water, energy, climate change--grounding each in historical context and weighing the options for the future. With our civilization on the line, the author's insightful analysis is an essential addition to the urgent conversation about how our children will fare on an increasingly crowded Earth.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Its geology, its unique flora and fauna, and its striking role in human history intersect in surprising and dynamic ways. This book is the most wide-ranging and beautifully illustrated book available on the famous islands. Not since Darwin’s Naturalist’s Voyage has a book combined so much scientific and historic information with firsthand accounts that bring the Galápagos to life.Galápagos: The Islands That Changed the World describes how tragedy and murderous pirates curtailed settlement of the islands and how the islands’ pristine nature, spectacular geology, and defining isolation inspired Darwin’s ideas about evolution. The book explores the diverse land and marine habitats that shelter Galápagos species and considers the islands’ importance today as a frontier for science and a refuge for true wilderness. The book’s extensive gazetteer provides details about endemic plants and animals as well as travel advice about visitors’ sites, diving, photography, when to go, and what to take. Vividly illustrated throughout, this guide is an indispensable reference for natural history enthusiasts, armchair travelers, and island visitors alike.