This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You'll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what's going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you'll be searching databases and analyzing sequences like a pro!

    Sipser's candid, crystal-clear style allows students at every level to understand and enjoy this field. His innovative "proof idea" sections explain profound concepts in plain English. The new edition incorporates many improvements students and professors have suggested over the years, and offers updated, classroom-tested problem sets at the end of each chapter.

    Some books try to give you copy-and-paste instructions for how to deal with every single system issue that may arise, but How Linux Works actually shows you how the Linux system functions so that you can come up with your own solutions. After a guided tour of filesystems, the boot sequence, system management basics, and networking, author Brian Ward delves into open-ended topics such as development tools, custom kernels, and buying hardware, all from an administrator's point of view. With a mixture of background theory and real-world examples, this book shows both "how" to administer Linux, and "why" each particular technique works, so that you will know how to make Linux work for you.

    This book introduces you to R, RStudio, and the tidyverse, a collection of R packages designed to work together to make data science fast, fluent, and fun. Suitable for readers with no previous programming experience, R for Data Science is designed to get you doing data science as quickly as possible. Authors Hadley Wickham and Garrett Grolemund guide you through the steps of importing, wrangling, exploring, and modeling your data and communicating the results. You’ll get a complete, big-picture understanding of the data science cycle, along with basic tools you need to manage the details. Each section of the book is paired with exercises to help you practice what you’ve learned along the way. You’ll learn how to: Wrangle—transform your datasets into a form convenient for analysis Program—learn powerful R tools for solving data problems with greater clarity and ease Explore—examine your data, generate hypotheses, and quickly test them Model—provide a low-dimensional summary that captures true "signals" in your dataset Communicate—learn R Markdown for integrating prose, code, and results

    A simple web search picks out a handful of relevant needles from the world's biggest haystack: the billions of pages on the World Wide Web. Uploading a photo to Facebook transmits millions of pieces of information over numerous error-prone network links, yet somehow a perfect copy of the photo arrives intact. Without even knowing it, we use public-key cryptography to transmit secret information like credit card numbers; and we use digital signatures to verify the identity of the websites we visit. How do our computers perform these tasks with such ease? This is the first book to answer that question in language anyone can understand, revealing the extraordinary ideas that power our PCs, laptops, and smartphones. Using vivid examples, John MacCormick explains the fundamental "tricks" behind nine types of computer algorithms, including artificial intelligence (where we learn about the "nearest neighbor trick" and "twenty questions trick"), Google's famous PageRank algorithm (which uses the "random surfer trick"), data compression, error correction, and much more. These revolutionary algorithms have changed our world: this book unlocks their secrets, and lays bare the incredible ideas that our computers use every day.

    This book covers relevant geometric principles and how to represent objects algebraically so they can be computed and applied. Recent major developments in the theory and practice of scene reconstruction are described in detail in a unified framework. Richard Hartley and Andrew Zisserman provide comprehensive background material and explain how to apply the methods and implement the algorithms. First Edition HB (2000): 0-521-62304-9

    The principal enhancement in Java 8 was the addition of functional programming constructs to Java's object-oriented roots. Java 7, 8, and 9 also introduced language features, such as the try-with-resources statement, the diamond operator for generic types, default and static methods in interfaces, the @SafeVarargs annotation, and modules. New library features include pervasive use of functional interfaces and streams, the java.time package for manipulating dates and times, and numerous minor enhancements such as convenience factory methods for collections. In this new edition of Effective Java, Bloch updates the work to take advantage of these new language and library features, and provides specific best practices for their use. Java's increased support for multiple paradigms increases the need for best-practices advice, and this book delivers. As in previous editions, each chapter consists of several "items," each presented in the form of a short, standalone essay that provides specific advice, insight into Java platform subtleties, and updated code examples. The comprehensive descriptions and explanations for each item illuminate what to do, what not to do, and why. Coverage includes:Updated techniques and best practices on classic topics, including objects, classes, methods, libraries, and generics How to avoid the traps and pitfalls of commonly misunderstood subtleties of the platform Focus on the language and its most fundamental libraries, such as java.lang and java.util

    Emphasis is placed upon the theoretical basis of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations. The text also introduces students to elementary integrated circuitry, microprocessors and computers, and treatment of analytical data.

    Problems are designed to progressively enhance MATLAB-use proficiency, so students need not be familiar with MATLAB at the start of your course. Program scripts that are answers to exercises in the text are available at no charge in electronic form (see Teaching Resources below). *Supplement and Review Mini-Chapters after each of the text's three parts contain an extensive review list of terms, test-like problem sets with answers, and detailed suggestions on supplemental reading to reinforce students' learning and help them prepare for exams. *Read-Only Chapters, strategically placed to provide a change of pace during the course, provide informative, yet enjoyable reading for students. *Measurement Details and Results samples offer students a realistic perspective on the seldom-perfect nature of device characteristics, contrary to the way they are often represented in introductory texts. Content Highlig

    And through CODE, we see how this ingenuity and our very human compulsion to communicate have driven the technological innovations of the past two centuries. Using everyday objects and familiar language systems such as Braille and Morse code, author Charles Petzold weaves an illuminating narrative for anyone who’s ever wondered about the secret inner life of computers and other smart machines. It’s a cleverly illustrated and eminently comprehensible story—and along the way, you’ll discover you’ve gained a real context for understanding today’s world of PCs, digital media, and the Internet. No matter what your level of technical savvy, CODE will charm you—and perhaps even awaken the technophile within.

    We have Mindstorms to thank for that. In this book, pioneering computer scientist Seymour Papert uses the invention of LOGO, the first child-friendly programming language, to make the case for the value of teaching children with computers. Papert argues that children are more than capable of mastering computers, and that teaching computational processes like de-bugging in the classroom can change the way we learn everything else. He also shows that schools saturated with technology can actually improve socialization and interaction among students and between students and teachers.

    As a professional C++ developer and former Harvard teaching fellow, I know what you need to know to be a great C++ programmer, and I know how to teach it, one step at a time. I know where people struggle, and why, and how to make it clear. I cover every step of the programming process, including:Getting the tools you need to program and how to use them*Basic language feature like variables, loops and functions*How to go from an idea to code*A clear, understandable explanation of pointers*Strings, file IO, arrays, references*Classes and advanced class design*C++-specific programming patterns*Object oriented programming*Data structures and the standard template library (STL)Key concepts are reinforced with quizzes and over 75 practice problems.

    In this unconventional introduction, physicist Leonard Susskind and hacker-scientist George Hrabovsky offer a first course in physics and associated math for the ardent amateur. Unlike most popular physics books—which give readers a taste of what physicists know but shy away from equations or math—Susskind and Hrabovsky actually teach the skills you need to do physics, beginning with classical mechanics, yourself. Based on Susskind's enormously popular Stanford University-based (and YouTube-featured) continuing-education course, the authors cover the minimum—the theoretical minimum of the title—that readers need to master to study more advanced topics.An alternative to the conventional go-to-college method, The Theoretical Minimum provides a tool kit for amateur scientists to learn physics at their own pace.

    Aiming to tell the dark secrets of computer arithmetic, this title is suitable for library developers, compiler writers, and lovers of elegant hacks.

    This resource guides readers through conducting a high-tech investigation, from acquiring digital evidence to reporting its findings. Updated coverage includes new software and technologies as well as up-to-date reference sections, and content includes how to set up a forensics lab, how to acquire the proper and necessary tools, and how to conduct the investigation and subsequent digital analysis. It is appropriate for students new to the field, or as a refresher and technology update for professionals in law enforcement, investigations, or computer security. The book features free downloads of the latest forensic software, so readers can become familiar with the tools of the trade.