Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.Features: NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body. New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text Medical applications explain the clinical relevance of each topic Complete coverage of every tissue of the body CD-ROM with all the images from the textVisit www.LangeTextbooks.com to access valuable resources and study aids

    The Seventh Edition updates and revises material to reflect current advances in respiratory science but does not stray from the proven formula students and faculty have enjoyed since 1974.New updates include physiology of pulmonary capillaries, hypoxic pulmonary vasoconstriction, pulmonary edema, surface tension, elastic properties of the lung and chest wall, metabolic functions of the lung, and perinatal respiration. Ample illustrations and pedagogical features help clarify important equations and concepts. USMLE-style review questions at the end of each chapter help students review for class or boards.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    R. Reid shows how all the other industrialized democracies have achieved something the United States can’t seem to do: provide health care for everybody at a reasonable cost. In his global quest to find a possible prescription, Reid visits wealthy, free market, industrialized democracies like our own—including France, Germany, Japan, the U.K., and Canada—where he finds inspiration in example. Reid sees problems too: He finds poorly paid doctors in Japan, endless lines in Canada, mistreated patients in Britain, spartan facilities in France. In addition to long-established systems, Reid also studies countries that have carried out major health care reform. The first question facing these countries—and the United States, for that matter—is an ethical issue: Is health care a human right?The Healing of America lays bare the moral question at the heart of our troubled system, dissecting the misleading rhetoric surrounding the health care debate: Is health care a human right?

    With humor and insight, Melissa Mohr takes readers on a journey to discover how "swearing" has come to include both testifying with your hand on the Bible and calling someone a *#$&!* when they cut you off on the highway. She explores obscenities in ancient Rome and unearths the history of religious oaths in the Middle Ages, when swearing (or not swearing) an oath was often a matter of life and death. Holy Sh*t also explains the advancement of civility and corresponding censorship of language in the 18th century, considers the rise of racial slurs after World War II, examines the physiological effects of swearing and answers a question that preoccupies the FCC, the US Senate, and anyone who has recently overheard little kids at a playground: are we swearing more now than people did in the past?A gem of lexicography and cultural history, Holy Sh*t is a serious exploration of obscenity.

    Your life, your thoughts, your diseases, and your health are all the function of cells.But what do you really know about what goes on inside you?The last time most people thought about cells in any detail was probably in high school or a college general biology class. But the field of cell biology has advanced incredibly rapidly in recent decades, and a great deal of what we may have learned in high school and college is no longer accurate or particularly relevant.The Cell: Inside the Microscopic World that Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world.Dr. Joshua Z. Rappoport is at the forefront of this field, and he will take you on a journey to discover:A deeper understanding of how cells work and the basic nature of life on earth.Fascinating histories of some of the key discoveries from the seventeenth century to the last decade and provocative thoughts on the current state of academic research.The knowledge required to better understand the new developments that are announced almost weekly in science and health care, such as cancer, cellular therapies, and the potential promise of stem cells.The ability to make better decisions about health and to debunk the misinformation that comes in daily via media.Using the latest scientific research, The Cell illustrates the diversity of cell biology and what it all means for your everyday life.

    They’re detectives who solve mysteries about the human body.Diagnosing patients is about looking for clues, whether a persistent tickle in the back of the throat or confusion and memory loss. Just like detectives, good doctors sift through information until they arrive at the medical solution that fits best.Think you have what it takes to keep up with medical detective work? Find out with this second installment of Dr. Roy Benaroch’s thrilling look at medical mysteries from across history. Continuing the excitement of his earlier Audible Original, Medical Mysteries Across History, Pt.2 features cases involving ancient kings and military leaders, beloved philosophers and popular entertainers. You may know who some of these patients are - but you’ve almost certainly never heard their stories told from a doctor’s point of view.In each instance, you’ll learn about the medicine that was practiced during the patient’s life, and you’ll discover how modern medicine can shed light on the past. You’ll see how every life (and every disease) is a story and that these stories reveal the clues doctors need to make an accurate diagnosis. And you’ll discover that while a lot in medicine has certainly changed, the way doctors approach patients hasn’t changed very much at all.Think you can guess who these 10 mystery patients are? Pay attention. The medical and historical hints are there and waiting for you.©2020 Audible Originals, LLC (P)2020 Audible Originals, LLC.

    Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

    Viruses are disarmingly small and simple. Nevertheless, the smallpox virus killed over 300 million people in the twentieth century before it was eradicated in 1980. The AIDSvirus, HIV, is now the world's biggest killer infection and the single most common cause of death in Africa. In recent years, the outbreaks of several lethal viruses such as Ebola and Hantavirus have caused great public concern--yet most people remain woefully ill-informed.In this fascinating new book, Dorothy Crawford explains lucidly and accessibly all aspects of the natural history of these deadly parasites and discusses controversial subjects such as CFS and Gulf War Syndrome. The book considers issues such as how man has coped with viruses in the past, where newviruses come from, and whether it would be possible for a new virus to wipe out the human race. Professor Crawford illustrates her arguments with vivid and wide-ranging examples. The result is an informative and highly readable book, which will be read by all those who seek a deeper understanding ofthese minute but remarkably efficient killers.

    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

    But now, with revolutionary medical advances, death has become just another serious complication. As a young medical student, Dr. David Casarett was inspired by the story of a two-year-old girl named Michelle Funk. Michelle fell into a creek and was underwater for over an hour. When she was found she wasn’t breathing, and her pupils were fixed and dilated. That drowning should have been fatal. But after three hours of persistent work, a team of doctors and nurses was able to bring her back. It was a miracle. If Michelle could come back after three hours of being dead, what about twelve hours? Or twenty-four? What would it take to revive someone who had been frozen for one thousand years? And what does blurring the line between “life” and “death” mean for society? In Shocked, Casarett chronicles his exploration of the cutting edge of resuscitation and reveals just how far science has come. He begins in the eighteenth century, when early attempts at resuscitation involved public displays of barrel rolling, horseback riding (sort of), and blowing smoke up the patient’s various orifices. He then takes us inside a sophisticated cryonics facility in the Arizona desert, a darkroom full of hibernating lemurs in North Carolina, and a laboratory that puts mice into a state of suspended animation. The result is a spectacular tour of the bizarre world of doctors, engineers, animal biologists, and cryogenics enthusiasts trying to bring the recently dead back to life. Fascinating, thought-provoking, and (believe it or not) funny, Shocked is perfect for those looking for a prequel—and a sequel—to Mary Roach’s Stiff, or for anyone who likes to ponder the ultimate questions of life and death.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    When an epidemic hits, the EIS will be there to crack the case, however mysterious or deadly, saving countless lives in the process. Over the years they have successfully battled polio, cholera, and smallpox, to name a few, and in recent years have turned to the epidemics killing us now--smoking, obesity, and gun violence among them.The successful EIS model has spread internationally: former EIS officers on the staff of the Centers for Disease Control have helped to establish nearly thirty similar programs around the world. EIS veterans have gone on to become leaders in the world of public health in organizations such as the World Health Organization."Inside the Outbreaks" takes readers on a riveting journey through the history of this remarkable organization, following Epidemic Intelligence Service officers on their globetrotting quest to eliminate the most lethal and widespread threats to the world's health.