The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    As corporations seek to save money and government agencies aim to increase constituent access, minimum qualifications for the guardians of our nation’s healthcare continue to decline—with deadly consequences. This is a story that has not yet been told, and one that has dangerous repercussions for all Americans.

    

    Examples of analytical techniques are drawn from such areas as life sciences, clinical chemistry, air and water pollution, and industrial analyses. New to this edition: Excel spreadsheets on CD-ROM * New chapters on good laboratory practice, as well as genomics and proteomics * A more modern flavor.

    The world you live in is stranger than fiction... as you read this, you exist in other places at the same time. Do not regret having missed the chance to realize your dreams, for you may just have fulfilled it in another universe.. * Are the trillions of atoms that make you, nothing but vibrations in 10 dimensions?* Is it true that we are all connected with each other?* Can you go into the future to change the present?* Why do scientists and philosophers struggle with the concept of Time?* Can science explain consciousness through physics?* Is our fate driven by the underlying randomness in nature?* Is nature hiding the best-kept secrets which can never be unravelled by humans?The Speed of Time approaches the most complex and esoteric theories of science in lucid, clear and simple language and in the style of a thriller, leaving you wanting more... while addressing questions through the enigmatic theories in Physics such as Quantum Mechanics, Einstein's Theory of Relativity, Time, Chaos, and much more. Just start reading and you will not put it down.

    This is incidental as it is about neither of those industries in particular. It is about the magic and wonderment of those days as seen through the eyes of a child – my eyes! It is about the days when imagination was the biggest plaything that we possessed. The days when a plastic football provided a whole summer's play. It is about the scrapes that I found myself in and the things that I observed around me, and how they made me feel. All the stories are true and I personally experienced every one of them. The names of the characters have been changed. The reason being that I have no idea of the whereabouts of many of the characters contained within my stories, so I have no way of asking them for their permission to include them in this book. Some have possibly passed away, and it would be unfair of me to mention them without their blessing. Anyone who knows me will know who they are though.

    He takes you inside a typical interview by exploring the various types of case questions and he shares with you the acclaimed Ivy Case System which will give you the confidence to answer even the most sophisticated cases. The book includes over 40 strategy cases, ten case starts exercises and 21 ways to cut costs, plus much, much more!

    If you read nothing else on becoming a new manager, read these 10 articles. We've combed through hundreds of Harvard Business Review articles and selected the most important ones to help you transition from being an outstanding individual contributor to becoming a great manager of others. This book will inspire you to: - Develop your emotional intelligence- Influence your colleagues through the science of persuasion- Assess your team and enhance its performance- Network effectively to achieve business goals and for personal advancement- Navigate relationships with employees, bosses, and peers- Get support from above- View the big picture in your decision making- Balance your team's work and personal life in a high-intensity workplace. This collection of articles includes "Becoming the Boss," by Linda A. Hill; "Leading the Team You Inherit," by Michael D. Watkins; "Saving Your Rookie Managers from Themselves," by Carol A. Walker; "Managing the High-Intensity Workplace," by Erin Reid and Lakshmi Ramarajan; "Harnessing the Science of Persuasion," Robert B. Cialdini; "What Makes a Leader?" by Daniel Goleman; "The Authenticity Paradox," by Herminia Ibarra; "Managing Your Boss," by John J. Gabarro and John P. Kotter; "How Leaders Create and Use Networks," by Herminia Ibarra and Mark Lee Hunter; "Management Time: Who's Got the Monkey?" by William Oncken, Jr., and Donald L. Wass; and BONUS ARTICLE: "How Managers Become Leaders," by Michael D. Watkins.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    In the workplace today there's a glass wall. Men and women can see each other clearly through the divide, but they don't speak the same language or have the same expectations. And as a result, women and their careers are suffering.With more women than ever in the workforce, but still too few in the boardroom, now is the time to address the assumptions and miscommunication holding women back. This book gives women the tools they need to master any situation. Drawing on Unerman and Jacob's own experience in male-dominated businesses, as well as over a hundred interviews with both men and women, The Glass Wall provides clear, smart and easy-to apply strategies for success. From unlocking ambition and developing resilience to nurturing creativity and getting noticed, these are the skills that everyone needs to learn to help break down that wall and create better workplaces for all.

    The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    The bestselling textbook inorganic chemistry text on the market covers both theoretical and descriptive aspects of the subject, and emphasizes experimental methods, industrial applications, and modern topics.

     Although one in five Americans now takes at least one psychotropic drug, the fact remains that nearly seventy years after doctors first began prescribing them, we still don't know exactly how or why these drugs work--or don't work--on what ails our brains. Blue Dreams offers the explosive story of the discovery, invention, people, and science behind our licensed narcotics, as told by a riveting writer and psychologist who shares her own intimate experience with the highs and lows of psychiatry's drugs. Lauren Slater's account ranges from the earliest, Thorazine and lithium, up through Prozac and other antidepressants, as well as Ecstasy, "magic mushrooms," the most cutting-edge memory drugs, and even neural implants. Along the way, she narrates the history of psychiatry itself, illuminating the imprint its colorful little capsules have left on millions of brains worldwide, and demonstrating how these wonder drugs may heal us or hurt us.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    As you read through the job description, your excitement builds as you realize that the job is a perfect fit! Not wasting another second, you fill out the application, attach your resume, and hold your breath as you hit “Apply.” Then you wait. And wait. And wait some more. Weeks go by without hearing so much as a peep, and before long you’ve given up hope on what seemed like a match made in heaven. Sound familiar? You’re not alone! On average there are 250 resumes submitted for every job opening, which means that 99.6% of applicants will fail to land the jobs they apply for. To get the job you want, you don’t just need a great resume--you need an outstanding resume, one that puts you in the top 1% of candidates for the job. That means ditching the same old advice you’ve been following with little results and adopting a tried-and-true process for getting your resume noticed in even the most competitive situations. In this book, Dan Clay breaks down the exact method he’s carefully developed over a period of ten years and provides a precise, step-by-step set of instructions for crafting the perfect resume, down to the last period. Unlike the dime-a-dozen recruiters turned career coaches who have never had to put themselves on the line in today’s brutally competitive job market, Dan offers practical, real-world experience gained from applying for and getting job offers from some of the most prestigious, competitive companies in the world. And when it comes to something as important as your career, don’t you deserve to learn from someone who’s actually succeeded at doing what you’re hoping to do? Of course you do! Here are some of the things you’ll learn about how to transform your resume from average to awe-inspiring: How to handle tricky pitfalls like extended time off or unemployment and have your resume come out as strong as ever How to make your accomplishments sound dramatically more impressive without having to tell a single lie How to remove the guesswork about what to include in your resume and build it to the exacting specifications of your target job's requirements How to pass the four tests that companies will put your resume through with flying colors How to strike the perfect composition of content, white space, and page length to accentuate and differentiate your strengths How to avoid the common (and not so common) resume mistakes that leave your resume dead on arrival How to tell a powerful story that demonstrates your capabilities in a way that will knock the socks off anyone reading it How to stand out without resorting to cheap tricks that come off as cheesy or over-the-top PLUS, you’ll also gain access to a free companion website containing fully editable resume templates, a perfect resume checklist, and other bonus materials to give you everything you need to create a stunning resume that will get you noticed and land you interviews. Whether you’re a new graduate looking for your first job, a career veteran angling for your next move, a recent victim of a layoff, or someone looking to dip their toes back int