The Structure of Evolutionary Theory


Stephen Jay Gould - 2002
    Next, he examines the three critiques that currently challenge this classic Darwinian edifice: that selection operates on multiple levels, from the gene to the group; that evolution proceeds by a variety of mechanisms, not just natural selection; and that causes operating at broader scales, including catastrophes, have figured prominently in the course of evolution.Then, in a stunning tour de force that will likely stimulate discussion and debate for decades, Gould proposes his own system for integrating these classical commitments and contemporary critiques into a new structure of evolutionary thought.In 2001 the Library of Congress named Stephen Jay Gould one of America's eighty-three Living Legends--people who embody the quintessentially American ideal of individual creativity, conviction, dedication, and exuberance. Each of these qualities finds full expression in this peerless work, the likes of which the scientific world has not seen--and may not see again--for well over a century.

Principles of Biochemistry


Albert L. Lehninger - 1970
    Lehninger Principles of Biochemistry, Fourth Edition brings clarity and coherence to an often unwieldy discipline, while incorporating the field's most important recent developments and applications.

Fly: The Unsung Hero of Twentieth-Century Science


Martin Brookes - 2001
    In biology labs across the world, fruit flies are turning up answers to some of the basic questions of life. It's business as usual for the fly, which for generations has been defining biology's major landmarks. From genetics to development, behavior to aging, and evolution to the origin of species, the fruit fly has been a key player in some of the twentieth century's greatest biological discoveries.Techniques to pinpoint genes that play a role in human disease depend on genetic mapmaking principles first established with the fly. It was experiments on fruit flies that opened our eyes to the dangers of radiation to human health. In fact, everything from gene therapy to cloning to the Human Genome Project is built on the foundation of fruit fly research. Despite its many achievements, the fruit fly remains an unsung hero in the history of science. At last, here is a book that gives the fly its long overdue credit.In a highly original, witty, and irreverent style, Martin Brookes takes us through successive stages in the life cycle of the fly, each illustrating an important concept in biology. Some, such as the fundamentals of heredity, are well established; others, such as sexual warfare, learning, and memory, are still in their infancy. But whether flies are getting high on crack cocaine, enjoying the pleasures and pains of a boozy night out, being trained by punishment and reward, or struggling with insomnia, this book provides a glimpse of how one short life has informed almost every aspect of human existence. The result is a broad introduction to biology with insights into the practical realities of science.Often dismissed as irrelevant outside academic circles, the fruit fly, through this distinctive biography, will come to be recognized for what it really is: an icon of twentieth-century science and a window on our own biological world.

Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life


J. Craig Venter - 2013
    Craig Venter became the first to successfully create synthetic life putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution. In "Life at the Speed of Light," Venter presents a fascinating and authoritative study of this emerging field from the inside detailing its origins, current challenges and controversies, and projected effects on our lives. This scientific frontier provides an opportunity to ponder anew the age-old question What is life? and examine what we really mean by playing God. " Life at the Speed of Light "is a landmark work, written by a visionary at the dawn of a new era of biological engineering."

Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal


Kat Arney - 2020
    We get cancer because we can't avoid it—it's a bug in the system of life itself.Cancer exists in nearly every animal and has afflicted humans as long as our species has walked the earth. In Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal, Kat Arney reveals the secrets of our most formidable medical enemy, most notably the fact that it isn't so much a foreign invader as a double agent: cancer is hardwired into the fundamental processes of life. New evidence shows that this disease is the result of the same evolutionary changes that allowed us to thrive. Evolution helped us outsmart our environment, and it helps cancer outsmart its environment as well—alas, that environment is us.Explaining why "everything we know about cancer is wrong," Arney, a geneticist and award-winning science writer, guides readers with her trademark wit and clarity through the latest research into the cellular mavericks that rebel against the rigid biological "society" of the body and make a leap towards anarchy.We need to be a lot smarter to defeat such a wily foe—smarter even than Darwin himself. In this new world, where we know that every cancer is unique and can evolve its way out of trouble, the old models of treatment have reached their limits. But we are starting to decipher cancer's secret evolutionary playbook, mapping the landscapes in which these rogue cells survive, thrive, or die, and using this knowledge to predict and confound cancer's next move.Rebel Cell is a story about life and death, hope and hubris, nature and nurture. It's about a new way of thinking about what this disease really is and the role it plays in human life. Above all, it's a story about where cancer came from, where it's going, and how we can stop it.

Mendel in the Kitchen: A Scientist's View of Genetically Modified Foods


Nina V. Fedoroff - 2004
    Mendel in the Kitchen provides a clear and balanced picture of this tangled, tricky (and very timely) topic.Any farmer you talk to could tell you that we've been playing with the genetic makeup of our food for millennia, carefully coaxing nature to do our bidding. The practice officially dates back to Gregor Mendel--who was not a renowned scientist, but a 19th century Augustinian monk. Mendel spent many hours toiling in his garden, testing and cultivating more than 28,000 pea plants, selectively determining very specific characteristics of the peas that were produced, ultimately giving birth to the idea of heredity--and the now very common practice of artificially modifying our food.But as science takes the helm, steering common field practices into the laboratory, the world is now keenly aware of how adept we have become at tinkering with nature--which in turn has produced a variety of questions. Are genetically modified foods really safe? Will the foods ultimately make us sick, perhaps in ways we can't even imagine? Isn't it genuinely dangerous to change the nature of nature itself?Nina Fedoroff, a leading geneticist and recognized expert in biotechnology, answers these questions, and more. Addressing the fear and mistrust that is rapidly spreading, Federoff and her co-author, science writer Nancy Brown, weave a narrative rich in history, technology, and science to dispel myths and misunderstandings.In the end, Fedoroff arues, plant biotechnology can help us to become better stewards of the earth while permitting us to feed ourselves and generations of children to come. Indeed, this new approach to agriculture holds the promise of being the most environmentally conservative way to increase our food supply.

A Colorful Introduction to the Anatomy of the Human Brain


John P.J. Pinel - 1998
     Thousands of people inquire about and buy a competitor to this book each year. Unique layout compared to the competition Text is on the left page with illustration on facing page. A cover flap can cover the illustration's labels for easy self-testing. Up-to-date information covers the latest findings.

The Birth of the Mind: How a Tiny Number of Genes Creates The Complexities of Human Thought


Gary F. Marcus - 1963
    nurture debate by linking the findings of the Human Genome Project to the development of the brain. Scientists have long struggled to understand how a tiny number of genes could contain the instructions for building the human brain, arguably the most complex device in the known universe. Synthesizing up-to-the-minute research with his own original findings on child development, Marcus is the first to resolve this apparent contradiction. Vibrantly written and completely accessible to the lay reader, The Birth of the Mind will forever change the way we think about our origins and ourselves.

Genentech: The Beginnings of Biotech


Sally Smith Hughes - 2009
    Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.

Here Is a Human Being: At the Dawn of Personal Genomics


Misha Angrist - 2010
    Unlocking the secrets of our genomes opens the door to understanding why we are the way we are and potentially fixing what ails us, from cancer and diabetes to obesity and male pattern baldness. But what exactly will happen to this information? Will it be a boon or just another marketing tool?Here Is a Human Being is the first in-depth look at personal genomics—its larger-than-life research subjects; its entrepreneurs and do-it-yourselfers; its technology developers; and the bewildered physicians and regulators who must negotiate with it—and what it means to be a “public genome” in a world where privacy is already under siege.

Molecular Cell Biology


Harvey F. Lodish - 1992
    Molecular Cell Biology stands out from its peers in this course in that it provides a clear introduction to the techniques and experiments of scientists past and present, not just an "encyclopedia" of information.  This experimental emphasis, together with a solid pedagogical framework in the chapters, provides the clearest, most cutting-edge text available.

Sloths!


William Hartston - 2018
    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

Inorganic Chemistry


Catherine E. Housecroft - 2001
    It offers superior coverage of all key areas, including descriptive chemistry, MO theory, bonding, and physical inorganic chemistry. Chapter topics are presented in logical order and include: basic concepts; nuclear properties; an introduction to molecular symmetry; bonding in polyatomic molecules; structures and energetics of metallic and ionic solids; acids, bases, and ions in aqueous solution; reduction and oxidation; non-aqueous media; and hydrogen. Four special topic chapters, chosen for their currency and interest, conclude the book. For researchers seeking the latest information in the field of inorganic chemistry.

Microcosmos: Four Billion Years of Microbial Evolution


Lynn Margulis - 1986
    Margulis to create a vivid new picture of the world that is crucial to our understanding of the future of the planet. Addressed to general readers, the book provides a beautifully written view of evolution as a process based on interdependency and the interconnectedness of all life on the planet.

Charles Darwin: Voyaging


Janet Browne - 1995
    Yet only now, with the publication of Voyaging, the first of two volumes that will constitute the definitive biography, do we have a truly vivid and comprehensive picture of Darwin as man and as scientist. Drawing upon much new material, supported by an unmatched acquaintance with both the intellectual setting and the voluminous sources, Janet Browne has at last been able to unravel the central enigma of Darwin's career: how did this amiable young gentleman, born into a prosperous provincial English family, grow into a thinker capable of challenging the most basic principles of religion and science? The dramatic story of Voyaging takes us from agonizing personal challenges to the exhilaration of discovery; we see a young, inquisitive Darwin gradually mature, shaping, refining, and finally setting forth the ideas that would at last fall upon the world like a thunderclap in The Origin of Species.