Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    Several versions of Pearson's MyLab & Mastering products exist for each title, including customized versions for individual schools, and registrations are not transferable. In addition, you may need a CourseID, provided by your instructor, to register for and use Pearson's MyLab & Mastering products. Packages Access codes for Pearson's MyLab & Mastering products may not be included when purchasing or renting from companies other than Pearson; check with the seller before completing your purchase. Used or rental books If you rent or purchase a used book with an access code, the access code may have been redeemed previously and you may have to purchase a new access code. Access codes Access codes that are purchased from sellers other than Pearson carry a higher risk of being either the wrong ISBN or a previously redeemed code. Check with the seller prior to purchase. -- Nutrition: An Applied Approach, Fourth Edition introduces you to nutrition with an innovative, applied format that discourages rote memorization and promotes long-term understanding of the material. Building on your natural interest in nutrition, the authors demonstrate in a clear, conversational style how key nutritional information relates to your personal health and nutrition, and show how to debunk commonly held misconceptions.The applied approach is reflected in the functional organization of the micronutrient chapters, focusing on the vitamins and minerals and their primary functions within the body. The applied content is focused on key content areas: fluid and electrolyte balance, antioxidant function, bone health, and energy metabolism and blood health--topics of particular importance to instructors. You can easily grasp this accessible conceptual framework for understanding the role nutrients play in bodies and overall health.The Fourth Edition features MasteringNutrition(TM), an online homework, assessment, and tutorial system that allows instructors to personalize the nutrition course like never before with next generation course management tools. Master topics through interactive mini-lessons, quizzing, and immediate wrong-answer feedback.This program will provide a better teaching and learning experience--for you. Here's how: Personalize learning with MasteringNutrition Improve results quickly by mastering concepts from self-paced tutorials that feature immediate wrong-answer feedback and hints that emulate the office-hour experience to keep you on track.Help students visualize and understand tough topics: All-New Focus Figures appear in bold, full-page displays throughout the text to help teach you the toughest topics in nutrition. Emphasize applications: Practice core nutrition concepts by using MyDietAnalysis, a software system that allows you to complete a diet assignment and then enter the information to create a variety of reports, in addition to other tools. Note: You are purchasing a standalone product; MasteringNutrition does not come packaged with this content. If you would like to purchase both the physical text and MasteringNutrition search for ISBN-10: 0321908740/ISBN-13: 9780321908742. That package includes ISBN-10: 0321910397/ISBN-13: 9780321910394 and ISBN-10: 0321956737/ISBN-13: 9780321956736.MasteringNutrition is not a self-paced technology and should only be purchased when required by an instructor.

    Taking a functional approach and looking at issues from both times of war and of peace, editors John Baylis, James J. Wirtz, and Colin S. Gray analyze the conflicts themselves--as well as what can be learned from them. This new edition covers topics such as intelligence and strategy, strategic studies and its critics, as well as strategy in practice, providing a comprehensive and insightful collection of contributions from a team of leading experts in the field. FEATURES * Provides a more comprehensive analysis of strategic studies than any other text in its market * Brings together contributions from international experts * Incorporates excellent learning features throughout, including readers' guides, key points, questions, suggestions for further reading, and boxes * Accompanied by a comprehensive Companion Website (www.oup.com/uk/orc/bin/9780199548873) with case studies, weblinks, PowerPoint lecture slides, and a (password-protected) Test Bank of multiple choice questions NEW TO THIS EDITION * Expanded coverage of key issues such as intelligence, critics of strategic studies, and strategy in practice * New chapters on intelligence and strategy, strategic studies and its critics, and the practice of strategy * New case studies for the online resource centre, including a case on the 2006 war in Lebanon and a case on the Gaza conflict

    The authors capture students' interest with up-to-date coverage of cutting edge topics and research. This text will help students connect the science of genetics to the issues of today through interesting and thought-provoking applications. The sixth edition boasts the next generation of media integration including Gen CD-X (student CD-ROM and Companion Website).

    Across America, banks closed, schools canceled classes, farmers left their fields, and factories shut down so that everyone could go to the show. In this entertaining and provocative book, Janet Davis links the flowering of the early-twentieth-century American railroad circus to such broader historical developments as the rise of big business, the breakdown of separate spheres for men and women, and the genesis of the United States' overseas empire. In the process, she casts the circus as a powerful force in consolidating the nation's identity as a modern industrial society and world power.Davis explores the multiple "shows" that took place under the big top, from scripted performances to exhibitions of laborers assembling and tearing down tents to impromptu spectacles of audiences brawling, acrobats falling, and animals rampaging. Turning Victorian notions of gender, race, and nationhood topsy-turvy, the circus brought its vision of a rapidly changing world to spectators--rural as well as urban--across the nation. Even today, Davis contends, the influence of the circus continues to resonate in popular representations of gender, race, and the wider world.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

    Yet many of us know very little about a tragedy that may strike our own loved ones--and much of what we think we know is wrong. This clear and powerful book dismantles myth after myth to bring compassionate and accurate understanding of a massive international killer.Drawing on a fascinating array of clinical cases, media reports, literary works, and scientific studies, Thomas Joiner demolishes both moralistic and psychotherapeutic cliches. He shows that suicide is not easy, cowardly, vengeful, or selfish. It is not a manifestation of "suppressed rage" or a side effect of medication. Threats of suicide, far from being idle, are often followed by serious attempts. People who are prevented once from killing themselves will not necessarily try again.The risk for suicide, Joiner argues, is partly genetic and is influenced by often agonizing mental disorders. Vulnerability to suicide may be anticipated and treated. Most important, suicide can be prevented.An eminent expert whose own father's death by suicide changed his life, Joiner is relentless in his pursuit of the truth about suicide and deeply sympathetic to such tragic waste of life and the pain it causes those left behind.

    According to the authors,effective human resource management is necessary for a firm to gain true competitive advantage. The three challenges companies face are the global challenge,the challenge of meeting stakeholder needs,and the high performance work practices challenge. HUMAN RESOURCE MANAGEMENT provides students with the technical background needed to be a successful HR professional,to manage HR effectively,and most importantly to be a knowledgeable consumer of HR products and services. The text also emphasizes how managers can more effectively acquire,develop,compensate,and manage the internal and external environment that relates to the management of human resources.

    Urry develops this analysis through various levels - historical, economic, social, cultural and visual.Mass tourism is charted from its origins in the English seaside resorts to its development as a global industry. The economic impact and complex social relations involved in international tourism are explored. Changing patterns of tourism are shown to be connected to the broader cultural changes of postmodernism and related to the role of the service and middle classes. The author argues that we

    The unstated objective of his lecture (“Existentialism Is a Humanism”) was to expound his philosophy as a form of “existentialism,” a term much bandied about at the time. Sartre asserted that existentialism was essentially a doctrine for philosophers, though, ironically, he was about to make it accessible to a general audience. The published text of his lecture quickly became one of the bibles of existentialism and made Sartre an international celebrity.The idea of freedom occupies the center of Sartre’s doctrine. Man, born into an empty, godless universe, is nothing to begin with. He creates his essence—his self, his being—through the choices he freely makes (“existence precedes essence”). Were it not for the contingency of his death, he would never end. Choosing to be this or that is to affirm the value of what we choose. In choosing, therefore, we commit not only ourselves but all of mankind.This book presents a new English translation of Sartre’s 1945 lecture and his analysis of Camus’s The Stranger, along with a discussion of these works by acclaimed Sartre biographer Annie Cohen-Solal. This edition is a translation of the 1996 French edition, which includes Arlette Elkaïm-Sartre’s introduction and a Q&A with Sartre about his lecture.

     This long-awaited new edition reinstates significant portions of the original French text that were cut in the first English translation. Vital and groundbreaking, Beauvoir’s pioneering and impressive text remains as pertinent today as it was back then, and will continue to provoke and inspire generations of men and women to come.

    Sontag develops further the concept of 'transparency'. When anything can be photographed and photography has destroyed the boundaries and definitions of art, a viewer can approach a photograph freely with no expectations of discovering what it means. This collection of six lucid and invigorating essays, the most famous being "In Plato's Cave", make up a deep exploration of how the image has affected society.

    Imperative reading for all teachers and students of writing.”—ChoiceThis humorous and accessible classic on style calls for the return of wordplay and delight to writing instruction. Richard Lanham argues that many tomes on writing, with their trio of platitudes—clarity, plainness, sincerity—lie “upon the spirit like wet cardboard.”"People seldom write to be clear. They have designs on their fellow men. Pure prose is as rare as pure virtue, and for the same reasons…The Books [Lanham’s term for misguided composition textbooks], written for a man and world yet unfallen, depict a ludicrous process like this: 'I have an idea. I want to present this gift to my fellow man. I fix this thought clearly in mind. I follow the rules. Out comes a prose that gift-wraps thought in transparent paper.' If this sounds like a travesty, it’s because it is one. Yet it dominates prose instruction in America."—from Chapter 1Richard A. Lanham is professor emeritus of English at the University of California, Los Angeles, and president of Rhetorica, Inc., a consulting and editorial services company. He is the author of numerous books on writing, including A Handlist of Rhetorical Terms, Analyzing Prose, The Electronic Word, and most recently, The Economics of Attention.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    This best-selling text gives students a solid understanding of organic chemistry by stressing how fundamental reaction mechanisms function and reactions occur. With the addition of handwritten solutions, new cutting-edge molecular illustrations, updated spectroscopy coverage, seamless integration of molecular modeling exercises, and state-of-the-art multimedia tools, the 7th edition of Organic Chemistry clearly offers the most up-to-date approach to the study of organic chemistry.