In the new edition of Biochemistry, instructors will see the all the hallmark features that made this a consistent bestseller for the undergraduate biochemistry course: exceptional clarity and concision, a more biological focus, cutting-edge content, and an elegant, uncluttered design.  Accomplished in both the classroom and the laboratory, coauthors Jeremy Berg and John Tymoczko draw on the field's dynamic research to illustrate its fundamental ideas.

    Conventional wisdom may be wrong. In this controversial book, the eminent biologist Paul W. Ewald offers some startling arguments:-Germs appear to be at the root of heart disease, Alzheimer’s, schizophrenia, many forms of cancer, and other chronic diseases.-The greatest threats to our health come not from sensational killers such as Ebola, West Nile virus, and super-virulent strains of influenza, but from agents that are already here causing long-term infections, which eventually lead to debilitation and death. -The medical establishment has largely ignored the evidence that implicates these germs, to the detriment of our public health.-New evolutionary theories are available, which explain how germs function and offer opportunities for controlling these modern plagues — if we are willing to listen to them.Plague Time is an eye-opening exploration of the revolutionary new understanding of disease that may set the course of medical research for the twenty-first century.

    Well, I was diagnosed 24 years ago, and I still learned something new on every page.”—Michael Kinsley, Vanity Fair columnist and author of Old Age: A Beginner’s Guide Here is the book that John Vine and his wife, Joanne, wish they could have consulted when John was first diagnosed with Parkinson’s disease—a nontechnical, personal guide written from the patient’s perspective. Relying on his experiences over the past 12 years, John writes knowledgeably about all aspects of the disease. John also interviewed other Parkinson’s patients and their partners, whose stories and advice he includes throughout the book. “I wish we’d had John Vine’s book when my brother-in-law was diagnosed. The book is highly informative, unflinchingly honest, and reassuringly optimistic. It’s just what the doctor should have ordered.”—Cokie Roberts, best-selling author and political commentator on ABC News and NPR “John Vine details, in a compelling and accessible way, his experience with Parkinson’s disease. His book is an extraordinary guide to living successfully with Parkinson’s, and a must read for all who want to better understand the condition. Although diagnosed with Parkinson’s, my father lived an active and productive life until his death at age 94. As the book makes clear, while each patient’s journey is unique, common approaches are indispensable in treating the symptoms of the disease.”—Eric H. Holder, Jr. served as the 82nd Attorney General of the United States from 2009 to 2015 “John Vine has written the best primer I’ve ever read for newly diagnosed Parkinson’s patients and their families. It helps them cope with the shock of diagnosis, gives them (jargon-free) the scientific basics they need to know, describes the symptoms they may experience (making clear that every case is different) and catalogs the resources available to navigate living with Parkinson’s. John humanizes the book by describing his own experience and that of 22 other patients and their partners. I’d urge every neurologist to have copies of Vine’s primer on hand to help new PD on their journey forward.”—Morton Kondracke, author of Saving Milly: Love, Politics and Parkinson’s Disease and a member of the Founders' Council of the Michael J. Fox Foundation “My husband has PD, and I devoured this book. It’s wise, wonderfully readable, and, above all, helpful. Since John Vine has PD, he speaks with great authority about the challenges, both physical and psychological. If you have Parkinson’s, live with someone who has it, or just know someone battling the disease, A Parkinson’s Primer is for you.”—Lesley Stahl, award-winning television journalist on the CBS News program 60 Minutes “This is a remarkable book describing the personal experiences of many individuals, including the author, living with Parkinson’s disease. It captures the fact that although there are many possible symptoms in this disease, each person experiences different symptoms and copes with them in various ways. The thoughtful and insightful comments and coping strategies should be helpful for persons with PD, and their partners, regardless of the stage of the disease.”—Stephen Grill, MD, PhD, Director of the Parkinson’s & Movement Disorders Center of Maryland John M. Vine is a lawyer at Covington & Burling LLP in Washington, DC, where he is the senior member and former head of the firm’s employee benefits group. He was diagnosed with Parkinson’s in 2004.

    Chapters parallel most standard pathology texts and each chapter ends with a review test. Topics covered include general and basic pathology, major concepts of disease processes, and systemic pathology surveying principal disorders of each organ system. A comprehensive examination at the end of the book contains 500 USMLE-format questions. USMLE questions have all been updated to current USMLE format.The text is written in outline format for effective review. Icons indicate high-yield information that correlates with key pathology concepts.

    Revised to reflect the latest research in the field, this book emphasizes the relationships and concepts that link cell and tissue structures with their functions. A bonus image library CD-ROM featuring all the photos and illustrations from the text with "zoom in" and "zoom out" capability is also included.

    Organized conceptually around the major fields of medical endeavour - anatomy, physiology, pathology, pharmacology, surgery, obstetrics, psychiatry, pediatrics, and family medicine - this book is an accessible overview of medical history as a vibrant component of social, intellectual, and cultural history, and as a research discipline in its own right.Each chapter begins in antiquity and ends in the twentieth century. Throughout, Duffin shows that alternative interpretations can be found for most elements of our past and that topics of interest can go well beyond 'great men' and 'great discoveries' to include ideas, diseases, patients, institutions, and great mistakes. This approach does not mean that the 'great men' (and women) are neglected; rather they appear in context. Medical disasters such as chloramphenicol and thalidomide, are covered along with the triumphs, and examples from Canada's past, largely ignored in other medical histories, are included. A chapter on methodology, suggestions for further reading with special attention to Canadian sources, and a careful index make it possible to research a specific event or historical debate, or to satisfy a more general curiosity.By presenting the material in a structure that resonates with the broad outlines of medical training, and by focusing on the questions asked most often, this text is a relevant guide for students to the history of the profession they are about to embrace, and for those who would teach them, be they physicians or historians. Duffin's clear and entertaining prose and the many illustrations will help to demystify medicine for general readers and for students in other domains, such as history, philosophy, and sociology.

    Why We Get Sick compels readers to reexamine the age-old attitudes toward sickness. Line drawings.

    From biblical plagues, to the AIDS crisis, to supergerms of the future, this updated and revised edition of the original covers the whole gamut of diseases that have threatened humanity since its origins.It also includes a new chapter on the history of bioterrorism and the deplorable role it has played and is likely to play in the phenomenal diversity of diseases.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    Groundbreaking in every way when first published, this book is a simple, straightforward, direct calculus text. It's popularity is directly due to its broad use of applications, the easy-to-understand writing style, and the wealth of examples and exercises which reinforce conceptualization of the subject matter. The author wrote this text with three objectives in mind. The first was to make the book more student-oriented by expanding discussions and providing more examples and figures to help clarify concepts. To further aid students, guidelines for solving problems were added in many sections of the text. The second objective was to stress the usefulness of calculus by means of modern applications of derivatives and integrals. The third objective, to make the text as accurate and error-free as possible, was accomplished by a careful examination of the exposition, combined with a thorough checking of each example and exercise.

    You'll experience the rush of adrenaline and the pain of loss. You'll go beyond the lights and sirens to witness the instinct of intelligence, the courage and commitment that makes the EMT an unsung hero in one of the most vital and compelling medical dramas of our time.

    Here's how Dr Coleman describes this book: `However good your doctor is, and however much you may trust him or her, you must share the responsibility for your own health, and you must know when to tell your doctor if you think that the treatment with which he or she is providing you, could be causing problems. After all, if things go wrong, your nice friendly doctor is more likely to kill you than is a burglar a deranged relative or a drunken motorist. Remember: one in six people in hospital are there because they have been made ill by a doctor. I have built this book around ther twelve basic laws of medicine which I have, over the years, formulated for my own benefit as a doctor, an observer and a patient. I have illustrated each of the 12 laws with clinical anecdotes and scientific data.' Here, for example, is Coleman's First Law of Medicine: `If you are receiving treatment for an existing disease and you develop new symptoms then, until proved otherwise, you should assume that the new symptoms are caused by the treatment you are receiving.' Dr Vernon Coleman is the author of over 100 books - many of them international bestsellers. His books have sold over two million copies in hardback and paperback in the UK alone and have been translated into 25 languages. Dr Coleman has written columns and articles for many of the world's leading newspapers and magazines and has presented numerous TV and radio programmes based on his books. In the mid 1980s he devised the world's first medical software for use on home computers. For more information about Dr Coleman's books please see the Vernon Coleman page on Amazon or visit www.vernoncoleman.com What the papers say: Vernon Coleman writes brilliant books - Good Book Guide The calmest voice of reason - The Observer A godsend - Daily Telegraph Brilliant - The People No thinking person can ignore him - The Ecologist Marvellously succinct, refreshingly sensible - The Spectator Probably one of the most brilliant men alive today - Irish Times King of the media docs - The Independent Britain's leading health care campaigner - The Sun Britain's leading medical author - The Star Perhaps the best known health writer for the general public in the world today - The Therapist The patient's champion - Birmingham Post A persuasive writer whose arguments, based on research and experience, are sound - Nursing Standard The doctor who dares to speak his mind - Oxford Mail He writes lucidly and wittily - Good Housekeeping The man is a national treasure - What doctors don't tell you Compulsive reading - The Guardian His message is important - The Economist Revered guru of medicine - Nursing Times His advice is optimistic and enthusiastic - British Medical Journal It's impossible not to be impressed - Western Daily Press Outspoken and alert - Sunday Express Hard hitting - inimitably forthright - Hull Daily Mail Refreshingly forthright - Liverpool Daily Post Dr Coleman made me think again - BBC World Service