Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    David Agus tackles these fundamental questions and dismantles misperceptions about what “health” really means. Presenting an eye-opening picture of the human body and all the ways it works—and fails—Dr. Agus shows us how a new perspective on our individual health will allow us to achieve a long, vigorous life. Offering insights and access to powerful new technologies that promise to transform medicine, Dr. Agus emphasizes his belief that there is no “right” answer, no master guide that is “one size fits all.” Each one of us must get to know our bodies in uniquely personal ways, and he shows us exactly how to do that. A bold call for all of us to become our own personal health advocates, The End of Illness is a moving departure from orthodox thinking.

    Using the latest discoveries from the geological record, he argues that life might be its own worst enemy. This stands in stark contrast to James Lovelock's Gaia hypothesis--the idea that life sustains habitable conditions on Earth. In answer to Gaia, which draws on the idea of the good mother who nurtures life, Ward invokes Medea, the mythical mother who killed her own children. Could life by its very nature threaten its own existence?According to the Medea hypothesis, it does. Ward demonstrates that all but one of the mass extinctions that have struck Earth were caused by life itself. He looks at our planet's history in a new way, revealing an Earth that is witnessing an alarming decline of diversity and biomass--a decline brought on by life's own biocidal tendencies. And the Medea hypothesis applies not just to our planet--its dire prognosis extends to all potential life in the universe. Yet life on Earth doesn't have to be lethal. Ward shows why, but warns that our time is running out.Breathtaking in scope, The Medea Hypothesis is certain to arouse fierce debate and radically transform our worldview. It serves as an urgent challenge to all of us to think in new ways if we hope to save ourselves from ourselves.

    Tedford have spent the past 20 years studying the evolutionary history of the family Canidae. Both are well known for having established the modern framework for the evolutionary relationship of canids. Combining their research with Mauricio Ant�n's impeccable reconstructions of both extinct and extant species, Wang and Tedford present a remarkably detailed and nuanced portrait of the origin and evolution of canids over the past 40 million years.The authors cull their history from the most recent scientific research conducted on the vast collections of the American Museum of Natural History and other leading institutions. The fossil record of the Canidae, particularly those from their birth place in North America, are the strongest of their kind among known groups of carnivorans. Such a wonderfully detailed evolutionary history provides access to a natural history that is not possible with many other groups of carnivorans.With their rich fossil record, diverse adaptations to various environments, and different predatory specializations, canids are an ideal model organism for the mapping of predator behavior and morphological specializations. They also offer an excellent contrast to felids, which remain entrenched in extreme predatory specializations. The innovative illustrated approach in this book is the perfect accompaniment to an extremely important branch of animal and fossil study. It transforms the science of paleontology into a thrilling visual experience and provides an unprecedented reference for anyone fascinated by dogs.

    Confident America has been conquered, Satan prepares to initiate the final stage of his master plan, but it requires a willing partner—will she say yes?Convinced his demon general Lord Nefarious has successfully conquered America, Satan himself now decides it’s time for him to step out of the shadows and complete his master plan. But for it to succeed, he must find a willing partner… On the run, frightened, and alone, Rae is cornered one fateful night in a rundown motel room by the devil himself. He has a once-in-eternity offer for her—the chance to change the world forever. But to convince her to freely accept it, Satan needs to connect with Rae’s past, present, and future to prove to her he can be trusted after all. A showdown for the ages is officially on, and humanity hangs in the balance.

    

    That word is formication, and the implied sense of horror and fascination, contends Richard Conniff, is something many of us actually crave. His Spineless Wonders presents an unabashed wallow in the joy of formication. Spineless Wonders is an engaging, sophisticated, and humorous mix of natural history and human lore. Through his journalistic assignments, Richard Conniff has been in contact with invertebrates for more than twenty years - tarantulas in the upper Amazon region, dragonflies in Arizona, squid in Florida, and flies on the rim of his beer glass. Discoveries about the extraordinary habits and idiosyncrasies of the moth, the leech, the ant, and the slime eel are opening new frontiers in the exploration of our natural universe. Spineless Wonders takes us directly to these wild and wonderful outposts to observe the hazards of being around invertebrates, the bizarre adaptions that enable them to survive in the world, and also the astonishing work they do - work that enables us to survive.

    We currently see no evidence of any kind indicating that extraterrestrials exist outside of our solar system. But at this moment, millions of engineers, scientists, corporations, universities and entrepreneurs are racing to create the second intelligent species right here on planet earth. And we can see the second intelligent species coming from all directions in the form of self-driving cars, automated call centers, chess-playing and Jeopardy-playing computers that beat all human players, airport kiosks, restaurant tablet systems, etc. The frightening thing is that these robots will soon be eliminating human jobs in startling numbers. The first wave of unemployed workers is likely to be a million truck drivers who are replaced by self-driving trucks. Pilots will be eliminated soon as well. Then, as new computer vision systems come online, we will see tens of millions of workers in retail stores, fast food restaurants and construction sites replaced by robots. Unless we take steps now to change the economy, we will soon have tens of millions of workers who are unemployed and seeking welfare because they will have no other choice. Marshall Brain's new book "The Second Intelligent Species: How Humans Will Become as Irrelevant as Cockroaches" explores how the future will unfold as the second intelligent species emerges. The book answers questions like: - How will new computer vision systems affect the job market? - How many people will become unemployed by the second intelligent species? - What will happen to millions of newly unemployed workers? - How can modern society and modern economies cope with run-away unemployment caused by robots? - What will happen when the first sentient, conscious computer appears? - What moral and ethical principles will guide the second intelligent species? - Why do we see no extraterrestrials in our universe? "The Second Intelligent Species" offers a unique and fascinating look at the future of the human race, and the choices we will need to make to avoid massive unemployment and poverty worldwide as intelligent machines start eliminating millions of jobs.

    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

    In Beast and Man Mary Midgley, one of our foremost intellectuals, stresses continuities. What makes people tick? Largely, she asserts, the same things as animals. She tells us humans are rather more like other animals than we previously allowed ourselves to believe, and reminds us just how primitive we are in comparison to the sophistication of many animals. A veritable classic for our age, Beast and Man has helped change the way we think about ourselves and the world in which we live.

    Created in the 1890s by George Washington Vanderbilt, a member of one of America's wealthiest families, the estate combined a 250-room French Renaissance-style chateau with 125,000 acres of gardens, forests, and working farms. Biltmore House served as Vanderbilt's primary residence for almost 20 years. After Mr. Vanderbilt's death in 1914, life at Biltmore continued for his wife Edith and daughter Cornelia. In 1930, Cornelia Vanderbilt Cecil and her husband, Hon. John Francis Amherst Cecil, opened Biltmore House--the largest private home in the United States--to the public, firmly establishing the Asheville area as a major tourist destination.

    The Funniest Text Message Autocorrects, Wrong Numbers & Mishaps on Smartphones!

    He is celebrated for his words of wisdom as well as the alleged miracles that he performed while he was still alive. Yet as large as his acclaim may be, Aquinas has also had his fair share of detractors both during his lifetime and long thereafter.In the twentieth century, for example, esteemed British philosopher and writer Bertrand Russel went so far in his criticism as to say that he believed that Thomas Aquinas was not a philosopher in the classical sense of the word but rather that he relied more on dogmatic Catholic faith than any sense of inquiry or inductive reasoning. There are of course those that would vehemently argue the opinions of Bertrand Russel. While it is not the purpose of this book to take one side or the other, these arguments and criticisms will be examined as we delve into the history of this great thinker.Casting all accolades and critiques aside, in this book you will find the raw bare bones of the man who Thomas Aquinas came to be. Thomas Aquinas had an exceptional life of both major accomplishments and upsetting setbacks—here, we explore them in full.

    Our garbage has become a massive and exponentially growing problem in modern society. Eco-entrepreneur Tom Szaky explores why this crisis exists and explains how can we solve it by eliminating the very idea of garbage. To outsmart waste, he says, we first have to understand it, then change how we create it, and finally rethink what we do with it.By mimicking nature and focusing on the value inherent in our by-products, we can transform the waste we can’t avoid creating from useless trash to a useful resource. Szaky demonstrates that there is value in every kind of garbage, from used chewing gum to juice pouches to cigarette butts. After reading this mind-expanding book, you will never think about garbage the same way again.

    Spanning evolutionary science from its inception to its latest findings, from discoveries and data to philosophy and history, this book is an authoritative introduction to evolutionary biology.