It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    This title shows us how to examine, study, and appreciate microbes in the manner of a birdwatcher, by making sightings of microbial activities and thereby identifying particular microbes as well as understanding what they do and how they do it.

    Paul Colinvaux takes a penetrating look at the science of ecology, bringing to his subject both profound knowledge and an enthusiasm that will encourage a greater understanding of the environment and of the efforts of those who seek to preserve it.

    Carroll at his very best.--Bill Bryson, author of The Body: A Guide for Occupants From acclaimed writer and biologist Sean B. Carroll, a rollicking, awe-inspiring story of the surprising power of chance in our lives and the worldWhy is the world the way it is? How did we get here? Does everything happen for a reason or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.Like every other species, we humans are here by accident. But it is shocking just how many things--any of which might never have occurred--had to happen in certain ways for any of us to exist. From an extremely improbable asteroid impact, to the wild gyrations of the Ice Age, to invisible accidents in our parents' gonads, we are all here through an astonishing series of fortunate events. And chance continues to reign every day over the razor-thin line between our life and death.This is a relatively small book about a really big idea. It is also a spirited tale. Drawing inspiration from Monty Python, Kurt Vonnegut, and other great thinkers, and crafted by one of today's most accomplished science storytellers, A Series of Fortunate Events is an irresistibly entertaining and thought-provoking account of one of the most important but least appreciated facts of life.

    The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Each concept is quick and easy to remember, described by means of an easy-to-understand picture and a maximum 200-word explanation. Concepts span all of the key areas of mathematics, including Fundamentals of Mathematics, Sets and Numbers, Geometry, Equations, Limits, Functions and Calculus, Vectors and Algebra, Complex Numbers, Combinatorics, Number Theory, Metrics and Measures and Topology. Incredibly quick - clear artworks and simple explanations that can be easily remembered. Based on scientific research that the brain best absorbs information visually. Compact and portable format - the ideal, handy reference.

    The emphasis is, instead, on the myriad ways in which the universe presents itself to us--and how, as observers and participants in its processes, we respond to it. "Life, like a dome of many-colored glass," wrote Percy Bysshe Shelley, "stains the white radiance of eternity." The author seeks here to explore the variety that gives life its beauty.Taken from Dyson's recent public lectures--delivered to audiences with no specialized knowledge in hard sciences--the book begins with a consideration of the practical and political questions surrounding biotechnology. As he seeks how best to explain the place of life in the universe, Dyson then moves from the ethical to the purely scientific. The book concludes with an attempt to understand the implications of biology for philosophy and religion.The pieces in this collection touch on numerous disciplines, from astronomy and ecology to neurology and theology, speaking to the lay reader as well as to the scientist. As always, Dyson's view of human nature and behavior is balanced, and his predictions of a world to come serve primarily as a means for thinking about the world as it is today.

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.

    Which is too bad for them, because anybody who's ever taken a peak under the hood knows that the human body, and all its various structures and functions, is a realm of awe-inspiring complexity and countless wonders. The dizzying dance of molecule, cell, tissue, organ, muscle, sinew, and bone that we call life can be a thing of breathtaking beauty and humbling perfection. No one should be denied access to this spectacle because they don't come from a scientific background. And now, thanks to Anatomy and Physiology For Dummies, no one needs to be. Whether you're an aspiring health-care or fitness professional or just somebody who's curious about the human body and how it works, this book offers you a fun, easy way get a handle on the basics of anatomy and physiology. In no time you'll:Understand the meanings of terms in anatomy and physiology Get to know the body's anatomical structures--from head to toe Explore the body's systems and how they interact to keep us alive Gain insights into how the structures and systems function in sickness and health Understand the human reproductive system and how it creates new life Written in plain English and illustrated with dozens of beautiful illustrations, Anatomy and Physiology For Dummies covers everything from atoms to cells to organs, including:Anatomic position and the divisions of the body Increasingly magnified aspects of the body, from atoms to organs to systems The anatomy and pathophysiology of the skeleton, muscles and skin The anatomy, physiology, pathophysiology of the nervous, endocrine and circulatory systems The anatomy, physiology, and pathophysiology of the respiratory, digestive, urinary and immune systems The anatomy, physiology, and pathophysiology of the reproductive system Keeping the body healthy through good nutrition Don't miss this opportunity to learn about your body from the inside out. Let Anatomy and Physiology For Dummies be your guide on a fantastic voyage through a world of countless wonders.

    Its effects on our view of life have been wide and deep. One of the most world-shaking books ever published, Charles Darwin's On the Origin of Species, first appeared in print over 130 years ago, and it touched off a debate that rages to this day.Every modern evolutionist turns to Darwin's work again and again. Current controversies in the life sciences very often have as their starting point some vagueness in Darwin's writings or some question Darwin was unable to answer owing to the insufficient biological knowledge available during his time. Despite the intense study of Darwin's life and work, however, many of us cannot explain his theories (he had several separate ones) and the evidence and reasoning behind them, nor do we appreciate the modifications of the Darwinian paradigm that have kept it viable throughout the twentieth century.Who could elucidate the subtleties of Darwin's thought and that of his contemporaries and intellectual heirs--A. R. Wallace, T. H. Huxley, August Weismann, Asa Gray--better than Ernst Mayr, a man considered by many to be the greatest evolutionist of the century? In this gem of historical scholarship, Mayr has achieved a remarkable distillation of Charles Darwin's scientific thought and his enormous legacy to twentieth-century biology. Here we have an accessible account of the revolutionary ideas that Darwin thrust upon the world. Describing his treatise as "one long argument," Darwin definitively refuted the belief in the divine creation of each individual species, establishing in its place the concept that all of life descended from a common ancestor. He proposed the idea that humans were not the special products of creation but evolved according to principles that operate everywhere else in the living world; he upset current notions of a perfectly designed, benign natural world and substituted in their place the concept of a struggle for survival; and he introduced probability, chance, and uniqueness into scientific discourse.This is an important book for students, biologists, and general readers interested in the history of ideas--especially ideas that have radically altered our worldview. Here is a book by a grand master that spells out in simple terms the historical issues and presents the controversies in a manner that makes them understandable from a modern perspective.

    New technologies have revealed secrets locked in prehistoric bones that no one could have previously predicted. We can now work out the color of dinosaurs, the force of their bite, their top speeds, and even how they cared for their young.Remarkable new fossil discoveries—giant sauropod dinosaur skeletons in Patagonia, dinosaurs with feathers in China, and a tiny dinosaur tail in Burmese amber—remain the lifeblood of modern paleobiology. Thanks to advances in technologies and methods, however, there has been a recent revolution in the scope of new information gleaned from such fossil finds.In Dinosaurs Rediscovered, leading paleontologist Michael J. Benton gathers together all the latest paleontological evidence, tracing the transformation of dinosaur study from its roots in antiquated natural history to an indisputably scientific field. Among other things, the book explores how dinosaur remains are found and excavated, and especially how paleontologists read the details of dinosaurs’ lives from their fossils—their colors, their growth, and even whether we will ever be able to bring them back to life. Benton’s account shows that, though extinct, dinosaurs are still very much a part of our world.

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.