It Combines Comprehensive Medical Content With Dynamic New Features And Interactive Technology To Better Support Instructors And To Help Prepare Students For The Field. An Interactive Skills DVD Is Also Packaged Free With Each Copy Of The Text.

    Fascinating... may presage a paradigm shift in medicine." --Kirkus Reviews (starred review)Teeming with information and big ideas... Outstanding."--Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases.The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies--a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases--which now account for 63 percent of all human deaths.Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.

    We all have one, but most of us will never see one. The heart surgeon now has that privilege but, for centuries, the heart was out of reach even for surgeons. So when a surgeon nowadays opens up a ribcage and mends a heart, it remains something of a miracle, even if, to some, it is merely plumbing. As with plumbers, the quality of surgeons’ work varies. As with plumbers, surgeons’ opinion of their own prowess and their own attitude to risk are not always reliable. Measurement is key. We’ve had a century of effective evidence-based medicine. We’ve had barely a decade of thorough monitoring of clinical outcomes. Thanks to the ground-breaking risk modelling of pioneering surgeons like Samer Nashef, we at last know how to judge whether an operation is in a patient’s best interest, which hospital and surgeon would be best for that operation, when it might best be performed and what the exact level of risk is. We have at last made what is important in surgery measurable. But how should surgeons, and their patients, use these newfound insights? Ever since his days as a medical student, Samer Nashef has challenged the medical profession to be more open and more accurate about the success of surgical procedures, for the sake of the patients. In The Naked Surgeon, he unclothes his own profession to demonstrate to his reader (and prospective patient) many revelations, such as the paradox at the heart of the cardiac surgeon’s craft: the more an operation is likely to kill you, the better it is for you. And he does so with absolute clarity, fluency and not a little wit.

    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.

    A gifted writer, Vertosick shows us that intelligence - the ability to react to the outside world, to change behaviour, to survive - can be found wherever life exists. He demonstrates the keen intelligence of our immune system, how lowly bacteria mutate and outwit antibiotics, and how canny cancer cells elude our natural defences.

    Now genetics is exploding, and before long we will have the complete code, written in three thousand million letters of DNA, of what makes a human being.

    And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization.From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again.Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

    Mythologized. Controversial.A Harvard evolutionary biologist debunks the myths and cultural stereotypes surrounding testosterone and reveals its far-reaching effects on gender and sexuality, sports, relationships, and many more aspects of our everyday lives.The biological source of virility and masculinity has inspired fascination, investigation, and controversy since antiquity. From the eunuchs in the royal courts of ancient China to the booming market for “elixirs” of youth in nineteenth-century Europe, humans have been obsessed with identifying and manipulating what we now know as testosterone. And the trends show no signs of slowing down—the modern market for testosterone supplements is booming. Thanks to this history and the methods of modern science, today we have a rich body of research about testosterone’s effects in both men and women.The science is clear: testosterone is a major, invisible player in our relationships, sex lives, athletic abilities, childhood play, gender transitions, parenting roles, violent crime, and so much more. But there is still a lot of pushback to the idea that it does, in fact, cause sex differences and significantly influence behavior.Carole Hooven argues in T that acknowledging testosterone as a potent force in society doesn’t reinforce stifling gender norms or patriarchal values. Testosterone and evolution work together to produce a huge variety of human behavior, and that includes a multitude of ways to be masculine or feminine. Understanding the science sheds light on how we work and relate to one another, how we express anger and love, and how we can fight bias and problematic behavior to build a more fair society.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    The Seventh Edition updates and revises material to reflect current advances in respiratory science but does not stray from the proven formula students and faculty have enjoyed since 1974.New updates include physiology of pulmonary capillaries, hypoxic pulmonary vasoconstriction, pulmonary edema, surface tension, elastic properties of the lung and chest wall, metabolic functions of the lung, and perinatal respiration. Ample illustrations and pedagogical features help clarify important equations and concepts. USMLE-style review questions at the end of each chapter help students review for class or boards.

    Whether the ailment is a cold, the flu, diabetes, obesity or certain cancers, the likely cause is germs. Our ancient enemies have four families - bacteria, viruses, fungi, and protozoa - and many names: Ebola, E. coli, salmonella, norovirus, gonorrhea. . . Human beings are engaged in a "war on germs," in which we develop ever-more sophisticated weapons and defensive strategies. But it is a war we can never win. Our best plan for staying as healthy is to choose our battles carefully, and try to co-exist with germs as best we can. The Germ Code is a wise, witty and wonderfully readable guide to our relationship with these infinitesimal but infinitely powerful creatures. Microbiologist Jason Tetro takes us outside the lab and shows the enormous influence of germs upon humanity's past, present and future. He unlocks the mysteries of "the germ code" to reveal how these organisms have exploited our every activity and colonized every corner of the earth. From his own research and personal experience, Tetro relates how the most recent flu pandemic happened, how others may have been averted and how more may come about if we aren't careful. He also explains that not every germ is our foe, and offers advice on harnessing the power of good germs to stay healthy and make our planet a better place. The Germ Code is a fascinating journey through an unseen world, an essential manual to living in harmony with germs and a life-enhancing (as well as life-saving!) good read.

    Time-saving study tools help readers arrive at a complete understanding of human anatomy. KEY TOPICS: An Introduction to Anatomy, The Cell, Tissues and Early Embryology, The Integumentary System, The Skeletal System: Osseous Tissue and Skeletal Structure, The Skeletal System: Axial Division, The Skeletal System: Appendicular Division, The Skeletal System: Articulations, The Muscular System: Skeletal Muscle Tissue and Muscle Organization, The Muscular System: Axial Musculature, The Muscular System: Appendicular Musculature, Surface Anatomy and Cross-Sectional Anatomy, The Nervous System: Neural Tissue, The Nervous System: The Spinal Cord and Spinal Nerves, The Nervous System: The Brain and Cranial Nerves, The Nervous System: Pathways And Higher-Order Functions, The Nervous System:  Autonomic Division, The Nervous System: General and Special Senses, The Endocrine System, The Cardiovascular System: Blood, The Cardiovascular System: The Heart, The Cardiovascular System: Vessels and Circulation, The Lymphoid System, The Respiratory System, The Digestive System, The Urinary System, The Reproductive System, The Reproductive System: Embryology and HumanDevelopment. MARKET: For all readers interested in human anatomy.

    Paul A. Ruggieri has seen the good, the bad, and the ugly of his profession. In Confessions of a Surgeon, he pushes open the doors of the O.R. and reveals the inscrutable place where lives are improved, saved, and sometimes lost. He shares the successes, failures, remarkable advances, and camaraderie that make it exciting. He uncovers the truth about the abusive, exhaustive training and the arduous devotion of his old-school education. He explores the twenty-four-hour challenges that come from patients and their loved ones; the ethics of saving the lives of repugnant criminals; the hot-button issues of healthcare, lawsuits, and reimbursements; and the true cost of running a private practice. And he explains the influence of the white coat code of silence and why patients may never know what really transpires during surgery. Ultimately, Dr. Ruggieri lays bare an occupation that to most is as mysterious and unfamiliar as it is misunderstood. His account is passionate, illuminating, and often shocking-an eye-opening, never- before-seen look at real life, and death, in the O.R.

    Ninety per cent of women experience these symptoms some time between the ages of 40 and 60.Menopause and perimenopause (the hormonal rollercoaster years leading up to a woman's last period) are among our last taboo subjects. Hormone Replacement Therapy (HRT) - once widely prescribed as the magical secret of youth - has been shunned by women and their doctors for two decades. Dr Ginni Mansberg, one of Australia's most trusted health and wellbeing experts, is here to work through the evidence and bust the taboos out of the water. The M Word is all about you and your choices. Are you being offered the best solutions for your menopause issues? Because there are great solutions to help you thrive in this new stage of life.

    In this short book, he provides readers with a fictional account of how a real, new medical technology could revolutionize the future of medicine by curing with sound. THE TUMOR follows the present day experience of the fictional patient Paul, an otherwise healthy 35-year-old father who is diagnosed with a malignant brain tumor. Grisham takes readers through a detailed account of Paul’s treatment and his family’s experience that doesn’t end as we would hope. Grisham then explores an alternate future, where Paul is diagnosed with the same brain tumor at the same age, but in the year 2025, when a treatment called focused ultrasound is able to extend his life expectancy. Focused ultrasound has the potential to treat not just brain tumors, but many other disorders, including Parkinson’s, Alzheimer’s, hypertension, and prostate, breast and pancreatic cancer. For more information, you can visit The Focused Ultrasound Foundation’s website. Here you will find a video of Grisham on the TEDx stage with the Foundation’s chairman and a Parkinson’s patient who brings the audience to its feet sharing her incredible story of a focused ultrasound “miracle.” Readers will get a taste of the narrative they expect from Grisham, but this short book will also educate and inspire people to be hopeful about the future of medical innovation.