The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Stewart's Calculus is successful throughout the world because he explains the material in a way that makes sense to a wide variety of readers. His explanations make ideas come alive, and his problems challenge, to reveal the beauty of calculus. Stewart's examples stand out because they are not just models for problem solving or a means of demonstrating techniques--they also encourage readers to develp an analytic view of the subject. This edition includes new problems, examples, and projects. This version of Stewart's book introduced exponential and logarithmic functions in the first chapter and their limits and derivatives are found in Chapters 2 and 3.

    Integrated central case studies woven throughout each chapter, use real-life stories to give you a tangible and engaging framework around which to learn and understand the science behind environmental issues. Printed on FSC (Forest Stewardship Council) certified paper, the newly revised Fourth Edition engages you through the addition of new EnvisionIt photo essays.

    The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    For each body system, broad coverage of anatomy, physiology, pathology, diagnostic procedures, treatment procedures, and pharmacology is provided. The author emphasizes both terms built from Latin and Greek word parts, and modern English terms, helping students develop a full working word part vocabulary they can use to interpret any new term. This edition contains many new terms, and has been reorganized for more efficient learning. To eliminate confusion, Word Building tables have been removed from each chapter and the terms have been distributed throughout the pathology, diagnostic procedure, and treatment procedure tables, where they are more immediately relevant to students. Note: This ISBN is just the standalone book, if the customer wants the book/access card order the ISBN below; 133962032 / 9780133962031 Medical Terminology: A Living Language PLUS MyMedicalTerminologyLab with Pearson etext -- Access Card Package Package consists of: 0132843471 / 9780132843478 Medical Terminology: A Living Language 0133936236 / 9780133936230 MyMedicalTerminologyLab with Pearson etext - Access Card - Medical Terminology A Living Language

    New Spotlight figures integrate brief text and visuals for easy reading. This package contains: Fundamentals of Anatomy & Physiology, Ninth Edition

    / Eric P. Widmaier, Hershel Raff, Kevin T. Strang.Consists of animations and, learning activities such as quizzes and interactive diagrams.

    Field methods and scientific techniques have been updated throughout, and new emphasis is placed on climate change and its impact on human affairs. The latest information on topics as varied as the Iceman, Pleistocene extinctions, and Ilama domestication is included, along with the most up-to-date material on GIS and surveying technology. New topics will be introduced to emphasize the ever-changing face of modern archaeology, and additional special box features will be included, as well as discussion of the archaeological techniques needed to study the material culture of the twentieth and twenty-first centuries. A key component of the new edition will be the introduction of a dedicated Web site and study guide to accompany the textbook itself.

    It provides clear, simple explanations and concrete examples of complex concepts, making a wide variety of commonly used critical theories accessible to novices without sacrificing any theoretical rigor or thoroughness.This new edition provides in-depth coverage of the most common approaches to literary analysis today: feminism, psychoanalysis, Marxism, reader-response theory, new criticism, structuralism and semiotics, deconstruction, new historicism, cultural criticism, lesbian/gay/queer theory, African American criticism, and postcolonial criticism. The chapters provide an extended explanation of each theory, using examples from everyday life, popular culture, and literary texts; a list of specific questions critics who use that theory ask about literary texts; an interpretation of F. Scott Fitzgerald's The Great Gatsby through the lens of each theory; a list of questions for further practice to guide readers in applying each theory to different literary works; and a bibliography of primary and secondary works for further reading.

    It introduces the analysis of the key elements of language--sounds, words, structures and meanings, and provides a solid foundation in all of the essential topics. The third edition has been extensively revised to include new sections on important contemporary issues in language study, including language and culture, African American English, sign language, and slang. A comprehensive glossary provides useful explanations of technical terms, and each chapter contains a range of new study questions and research tasks, with suggested answers.

    Written by an author team, including a Noble Prize winner, this text presents the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the molecular discoveries that have changed the way the field of genetics is viewed.

    This annually updated collection of the most frequently tested high-yield facts and mnemonics delivers everything you need to pass the most anxiety-provoking exam of your career.

    This edition features optional quantitative reasoning boxes, basic equations throughout the book, new end-of-chapter problems, and a consolidated math appendix for professors who want to emphasize quantitative understanding in their course. Key figures have been annotated to guide student interpretation of difficult concepts. New two-page Cosmic Context illustration spreads throughout the book, and at the end of every part, visually tie together key concepts from across chapters and put them in context, driving home main ideas in a meaningful way.

    It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.