Like its predecessors, this updated Sixth Edition is organized around the periodic table of elements and provides a systematic treatment of the chemistry of all chemical elements and their compounds. It incorporates important recent developments with an emphasis on advances in the interpretation of structure, bonding, and reactivity.From the reviews of the Fifth Edition: "The first place to go when seeking general information about the chemistry of a particular element, especially when up-to-date, authoritative information is desired."--Journal of the American Chemical Society"Every student with a serious interest in inorganic chemistry should have [this book]."-- Journal of Chemical Education "A mine of information . . . an invaluable guide."-- Nature "The standard by which all other inorganic chemistry books are judged."-- Nouveau Journal de Chimie "A masterly overview of the chemistry of the elements."-- The Times of London Higher Education Supplement "A bonanza of information on important results and developments which could otherwise easily be overlooked in the general deluge of publications."-- Angewandte Chemie

    One of the world's leading astronomers, Robert Kirshner, takes readers inside a lively research team on the quest that led them to an extraordinary cosmological discovery: the expansion of the universe is accelerating under the influence of a dark energy that makes space itself expand. In addition to sharing the story of this exciting discovery, Kirshner also brings the science up-to-date in a new epilogue. He explains how the idea of an accelerating universe--once a daring interpretation of sketchy data--is now the standard assumption in cosmology today.This measurement of dark energy--a quality of space itself that causes cosmic acceleration--points to a gaping hole in our understanding of fundamental physics. In 1917, Einstein proposed the cosmological constant to explain a static universe. When observations proved that the universe was expanding, he cast this early form of dark energy aside. But recent observations described first-hand in this book show that the cosmological constant--or something just like it--dominates the universe's mass and energy budget and determines its fate and shape.Warned by Einstein's blunder, and contradicted by the initial results of a competing research team, Kirshner and his colleagues were reluctant to accept their own result. But, convinced by evidence built on their hard-earned understanding of exploding stars, they announced their conclusion that the universe is accelerating in February 1998. Other lines of inquiry and parallel supernova research now support a new synthesis of a cosmos dominated by dark energy but also containing several forms of dark matter. We live in an extravagant universe with a surprising number of essential ingredients: the real universe we measure is not the simplest one we could imagine.

    It provides the background needed to understand related drugs currently on the market, as well as drugs yet to be released. In simplifying a complex subject, this text focuses on the essentials of pharmacology. Large print is used to show need-to-know information, and small print is used for nice to know material. At the end of each chapter, a summary of major nursing implications helps in applying the material to real-world situations. This edition includes a new companion CD-ROM featuring NCLEX(R) examination-style review questions, a variety of electronic calculators, and animations depicting drug mechanisms and effects.Uses a prototype drug approach that places a strong emphasis on understanding over memorization - equipping students with the knowledge to learn not only about related drugs currently on the market, but also about those drugs that will be released once the student begins practice.Summaries of Major Nursing Implications at the end of each chapter provide an in-depth look at assessment, implementation, and ongoing evaluations.Utilizes large print for essential information and small print for nice-to-know information to help both faculty and students focus their limited classroom and study time on understanding the essentials.Concise drug summary tables present detailed information on individual drugs, including class, generic and trade names, dosages, routes, and indications.Key Points at the end of each chapter summarize content in a bulleted format to help students review important concepts.Prototype drug discussions employ a clear and consistent format with separate headings for Mechanism of Action; Pharmacologic Effects; Pharmacokinetics; Therapeutic Uses; Adverse Effects; Drug Interactions; and Preparations, Dosage, and Administration.An attractive full-color design adds visual interest, highlights key information, and facilitates student learning.Drugs for Multiple Sclerosis and Drugs for Hemophilia chapters.Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia chapter covers newsworthy drugs such as Viagra and Levitra.Special Interest Topics boxes on current issues in pharmacology, such as Medication-Overuse Headache: Too Much of a Good Thing and Face Time with Botox.Adult Immunization appendix summarizes the latest information on immunizations.Numerous new illustrations show drug mechanisms and effects, and depict topics such as histologic changes in Alzheimer's disease and the movement of drugs following GI absorption.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

    This book demonstrates how the notation and process complement one another, using UML models to illustrate the new process in action. It describes the constructs such as use cases, actors, and more.

    The OpenGL Programming Guide provides definitive and comprehensive information on OpenGL and the OpenGL Utility Library. It is far and away the most important book on OpenGL, and is commonly referred to by programmers simply as the Red book. Last summer the OpenGL Architectural Review Board (ARB) announced the release of the version 2.0 standard, incorporating the OpenGL Shader Language (GLSL) officially into the spec. This is the biggest change in OpenGL since its inception. This new edition will provide basic information about GLSL itself, as well as all the other changes to the 1.5 and 1.0 versions. the official, comprehensive guide to GLSL itself. A few years ago, pundits were predicting the imminent demise of OpenGL. Far from expiring, however, OpenGL has had a resurgence in the last couple years, and has solidified its position as the defacto standard for high-quality computer graphics. This book remains the necessary guide for any developer doing graphics programming. The sample source code in the book will be available on the book's web site.

    Jones and George are dedicated to the challenge of "Making It Real" for students. The authors present management in a way that makes its relevance obvious even to students who might lack exposure to a "real-life" management context. This is accomplished thru a diverse set of examples, and the unique, and most popular feature of the text, the "Manager as a Person" Chapter 2. This chapter discusses managers as real people with their own personalities, strengths, weaknesses, opportunities, and problems and this theme is carried thru the remaining chapters. This text also discusses the importance of management competencies--the specific set of skills, abilities, and experiences that gives one manager the ability to perform at a higher level than another in a specific context. The themes of diversity, ethics, globalization, and information technology are integrated throughout.

    Beginning with rape, and moving on to murder, war, and genocide, Ghiglieri offers the most up-to-date, comprehensive look at the male proclivity for violence. In a strong narrative voice, he draws on the latest research and his own personal experiences—both as a primatologist and as a soldier—to explain that male violence is largely innate, a product of millions of years of evolution. In the process, he debunks many of our most clung-to, “politically correct” notions: that the differences between men and women are strictly due to socialization, that rape is really about power—not sex—and that genocide is only possible with a single madman at the helm. Well-argued, evenhanded, yet never dull, this important book illuminates the darkest impulses of the male psyche, and suggests ways for modern society to curb them.