The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    Case Files: Family Medicine reviews 60 high-yield family medicine cases, each with USMLE-format review questions and clinical pearls that highlight key concepts. In this score-boosting resource, you'll find must-know family medicine cases in an interactive and memorable format written by experienced educators.

    Intermediate Accounting integrates this new information throughout the chapters so they'll learn how to apply the new global accounting standards. Global examples are presented to clearly show how the information is utilised in the field. The use of various currencies is also explored, which is critical for accountants to know in today's global businesses environment.

    It provides the background needed to understand related drugs currently on the market, as well as drugs yet to be released. In simplifying a complex subject, this text focuses on the essentials of pharmacology. Large print is used to show need-to-know information, and small print is used for nice to know material. At the end of each chapter, a summary of major nursing implications helps in applying the material to real-world situations. This edition includes a new companion CD-ROM featuring NCLEX(R) examination-style review questions, a variety of electronic calculators, and animations depicting drug mechanisms and effects.Uses a prototype drug approach that places a strong emphasis on understanding over memorization - equipping students with the knowledge to learn not only about related drugs currently on the market, but also about those drugs that will be released once the student begins practice.Summaries of Major Nursing Implications at the end of each chapter provide an in-depth look at assessment, implementation, and ongoing evaluations.Utilizes large print for essential information and small print for nice-to-know information to help both faculty and students focus their limited classroom and study time on understanding the essentials.Concise drug summary tables present detailed information on individual drugs, including class, generic and trade names, dosages, routes, and indications.Key Points at the end of each chapter summarize content in a bulleted format to help students review important concepts.Prototype drug discussions employ a clear and consistent format with separate headings for Mechanism of Action; Pharmacologic Effects; Pharmacokinetics; Therapeutic Uses; Adverse Effects; Drug Interactions; and Preparations, Dosage, and Administration.An attractive full-color design adds visual interest, highlights key information, and facilitates student learning.Drugs for Multiple Sclerosis and Drugs for Hemophilia chapters.Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia chapter covers newsworthy drugs such as Viagra and Levitra.Special Interest Topics boxes on current issues in pharmacology, such as Medication-Overuse Headache: Too Much of a Good Thing and Face Time with Botox.Adult Immunization appendix summarizes the latest information on immunizations.Numerous new illustrations show drug mechanisms and effects, and depict topics such as histologic changes in Alzheimer's disease and the movement of drugs following GI absorption.

    With an emphasis on critical self-reflection, Reflect & Relate gives students the practical skills to work through life's many challenges using better interpersonal communication. The sound theory, clear explanations, lively writing, practical activities, and vibrant design all work toward a single goal: Teaching students to make better communication choices so they can build happier and healthier interpersonal relationships.

    His designation grants him sweeping powers over the Indian security and intelligence apparatuses, and a say in foreign relations that he has exercised vigorously, particularly when it comes to the country’s neighbours. His outlook combines strident Hindu nationalism with habits learnt over his decades in the Intelligence Bureau. The results have been far from extraordinary—yet large sections of the media continue to laud him. Doval’s public persona as a super-spy and statesman may be too good to be true. The Caravan -India's finest magazine of politics, culture and business. Since its relaunch in 2010, The Caravan has earned a reputation as one of South Asia's most sophisticated publications, a showcase of the region's finest writers, with a distinctive blend of masterful reporting, unique criticism and stunning photo essays.

     Aside from the bipolar hillbillies, unfriendly wild animals, run-ins with the law, a mental breakdown, a bad first date, and a near-death experience . . . things actually went pretty well. Taking plenty of detours along the way, Rob’s contagious and hilarious sense of wanderlust carries him on a whirlwind road trip from the Smoky Mountains in the East, to Yellowstone, the Tetons, and Colorado’s snow-covered peaks in the West. In a refreshing style that brings these incredible wild places to life like no travel guide ever could, on seemingly every page we’re reminded of the one universal truth of travel . . . the best parts of any journey are the adventures we least expect.

    Photos & stories are a must read for all motorcycle riders" - "Sonny Barger " In the early 1960s, a young Navy vet, motorcyclist, amateur photographer, and rebel named Phil Cross joined a motorcycle club called the Hells Angels. It turned out to be a bogus chapter of the club that would soon find infamy, so he switched to another club called the Night Riders. Like the bogus chapter of the Hells Angels, this turned out to be a club whose brotherhood was run by a man Mr. Cross describes as a complete asshole. One day, Mr. Cross stuffed the leader in a ringer-type washing machine and joined a club called the Gypsy Jokers. He started a San Jose chapter of the Jokers and embarked on the most action-packed years of his life. The Jokers were in the midst of a shooting war with the real Hells Angels. The fighting became so intense that the Jokers posted snipers atop their clubhouse. This was a rough time, but it was also the height of the free-love hippie era, and as a young man, Phil enjoyed himself to the fullest. He never let anything as minor as a little jail time stop his fun. Once, while serving time for fighting and fleeing an officer, Phil broke out of jail, entered his bike in a bike show, won the bike show, and broke back into jail before anyone discovered he was missing. Though Phil was tough he was a certififed martial arts instructor the Angels proved a tough foe. After multiple beating-induced emergency room visits, Mr. Cross decided that if you can t beat em, join em, so he and most of his club brothers patched over to become the San Jose chapter of the Hells Angels. This book chronicles the life and wild times of Mr. Cross in words and photos.

    The honest, entertaining and often surprising autobiography of one of our favourite Loose Women.

    A cold-eyed killer who drank nothing stronger than weak tea, he fought with his bare hands, a sharpened shovel and piano wire. He was a larrikin who went by the book, unless the book was wrong. He set his own bar high and expected others to do the same.Stone Cold is the extraordinary story of one of Australia's most fearless fighters. It takes us into the jungles of New Guinea and Borneo and some of the fiercest battles of World War II. It goes to the cold heart of Korea, where Len emerged from the ranks to excel in the epic Battle of Kapyong and play a key role at the Battle of Maryang San. And it drops us into the centre of the American counterinsurgency war in Vietnam with Len's involvement in the CIA's shadowy black ops program, Phoenix.Action-packed and surprising, Stone Cold gives rich life to a warrior soldier and one of Australia's greatest diggers.

    Updated atlas contains maps of every U.S. state that are 35% larger than the standard atlas version plus over 350 detailed city inset and national park maps and a comprehensive, unabridged index. Road construction projects and updates highlighted for every state and conveniently located above the maps. Contains mileage chart showing distances between 77 North American cities and national parks with driving times map. Tough spiral binding allows the book to lay open easily. Other Features Best of the Road - Our editor's favorite road trips from our Best of the Road collection follows scenic routes along stretches of coastline, both east and west, to forests mountains, and prairies; and through small towns and big cities. For a weekend or a week there's something for everyone. Tell Rand! As much as we work to keep our atlases up to date, conditions change quickly and new construction projects begin frequently. If you know of something we haven't captured in our atlas, let us know at randmcnally.com/tellrand. Tourism websites and phone numbers for every U.S. state and Canadian province on map pages

    So began a desperate search for this precious child - conducted at the apex of the London Olympics by hundreds of police officers and volunteers. The disappearance of Tia Sharp was a tale of police blunders, misplaced trust, community spirit, and sadness. It was a case which shocked the nation and reminded us that, sometimes, the real monsters hide in plain sight.

    Little did they know that underneath his cool exterior lay a twisted desire to kill.Behind the facade of normality lay a psychopathic mind struggling to control its homicidal urges. Having seduced and married his sweetheart Mary Gough, Whelan immediately began planning her brutal murder.While his young wife dreamed of a love-filled marriage, Whelan searched the internet for information on serial killers and the methods they used to strangle their victims.Compelling and disturbing, this book reveals how Whelan murdered his wife to claim a hefty life insurance policy, and how he faked his own suicide when he became the prime suspect for the murder.Till Death Do Us Part offers a fascinating insight into the true motivation behind one of Irelands most notorious murders, and is a horrifying story of love, lust, revenge and murder - all the more shocking because every word is true.

    Ex-players, close friends, journalists, managers and former colleagues reveal their astonishing brushes with the greatest football manager England never had. The stories are cherry-picked from two acclaimed books - 150BC: Cloughie the Inside Stories and Clough: Confidential. An additional 242 stories can be found in these two volumes. So, enter the whirlwind world of Old Big 'Ead and prepare to be entertained.