Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

      “An unexpectedly intimate look into a highly accomplished man, his colleagues and friends, the development of a new field of geometric analysis, and a glimpse into a truly uncommon mind.”—Nina MacLaughlin, Boston Globe “Engaging, eminently readable . . . For those with a taste for elegant and largely jargon-free explanations of mathematics, The Shape of a Life promises hours of rewarding reading.”—Judith Goodstein, American Scientist  Harvard geometer and Fields medalist Shing-Tung Yau has provided a mathematical foundation for string theory, offered new insights into black holes, and mathematically demonstrated the stability of our universe. In this autobiography, Yau reflects on his improbable journey to becoming one of the world’s most distinguished mathematicians. Beginning with an impoverished childhood in China and Hong Kong, Yau takes readers through his doctoral studies at Berkeley during the height of the Vietnam War protests, his Fields Medal–winning proof of the Calabi conjecture, his return to China, and his pioneering work in geometric analysis. This new branch of geometry, which Yau built up with his friends and colleagues, has paved the way for solutions to several important and previously intransigent problems. With complicated ideas explained for a broad audience, this book offers readers not only insights into the life of an eminent mathematician, but also an accessible way to understand advanced and highly abstract concepts in mathematics and theoretical physics.

    Marvel at the Dual Slit experiment as a tiny atom passes through 2 separate openings at the same time. Ponder the peculiar communication of quantum particles, which can remain in touch no matter how far apart. Join the genius jewel thief as he carries out a quantum measurement on a diamond without ever touching the object in question. With its clean, colorful layout and conversational tone, this text will hook you into the conundrum that is quantum mechanics.

    The Structure of Scientific Revolutions is that kind of book. When it was first published in 1962, it was a landmark event in the history and philosophy of science. Fifty years later, it still has many lessons to teach. With The Structure of Scientific Revolutions, Kuhn challenged long-standing linear notions of scientific progress, arguing that transformative ideas don’t arise from the day-to-day, gradual process of experimentation and data accumulation but that the revolutions in science, those breakthrough moments that disrupt accepted thinking and offer unanticipated ideas, occur outside of “normal science,” as he called it. Though Kuhn was writing when physics ruled the sciences, his ideas on how scientific revolutions bring order to the anomalies that amass over time in research experiments are still instructive in our biotech age. This new edition of Kuhn’s essential work in the history of science includes an insightful introduction by Ian Hacking, which clarifies terms popularized by Kuhn, including paradigm and incommensurability, and applies Kuhn’s ideas to the science of today. Usefully keyed to the separate sections of the book, Hacking’s introduction provides important background information as well as a contemporary context.  Newly designed, with an expanded index, this edition will be eagerly welcomed by the next generation of readers seeking to understand the history of our perspectives on science.

    There are updates throughout the book as well. These take into account important advances in cognitive psychology and the science of design while confirming and extending the book's basic thesis: that a physical symbol system has the necessary and sufficient means for intelligent action. The chapter "Economic Reality" has also been revised to reflect a change in emphasis in Simon's thinking about the respective roles of organizations and markets in economic systems."People sometimes ask me what they should read to find out about artificial intelligence. Herbert Simon's book The Sciences of the Artificial is always on the list I give them. Every page issues a challenge to conventional thinking, and the layman who digests it well will certainly understand what the field of artificial intelligence hopes to accomplish. I recommend it in the same spirit that I recommend Freud to people who ask about psychoanalysis, or Piaget to those who ask about child psychology: If you want to learn about a subject, start by reading its founding fathers." -- George A. Miller

    It has found adherents in Silicon Valley billionaires Ray Kurzweil and Peter Diamandis. Google has entered the picture, establishing a bio-tech subsidiary aimed at solving the problem of aging.In To Be a Machine, journalist Mark O'Connell takes a headlong dive into this burgeoning movement. He travels to the laboratories, conferences, and basements of today's foremost transhumanists, where he's presented with the staggering possibilities and moral quandaries of new technologies like mind uploading, artificial superintelligence, cryonics, and device implants.A contributor to Slate, The New Yorker, and The New York Times Magazine, O'Connell serves as a sharp and lively guide to the outer limits of technology in the twenty first century. In investigating what it means to be a machine, he offers a surprising, singular meditation on what it means to be human."

    On March 14, 2013, physicists at CERN confirmed it. This elusive subatomic particle forms a field that permeates the entire universe, creating the masses of the elementary particles that are the basic building blocks of everything in the known world--from viruses to elephants, from atoms to quasars.     Starting where Nobel Laureate Leon Lederman's bestseller The God Particle left off, this incisive new book explains what's next. Lederman and Hill discuss key questions that will occupy physicists for years to come:      * Why were scientists convinced that something like the "God Particle" had to exist?      * What new particles, forces, and laws of physics lie beyond the "God Particle"?      * What powerful new accelerators are now needed for the US to recapture a leadership role in science and to reach "beyond the God Particle," such as Fermilab's planned Project-X and the Muon Collider?      Using thoughtful, witty, everyday language, the authors show how all of these intriguing questions are leading scientists ever deeper into the fabric of nature. Readers of The God Particle will not want to miss this important sequel.

    By 1949, Godel had produced a remarkable proof: In any universe described by the Theory of Relativity, time cannot exist. Einstein endorsed this result reluctantly but he could find no way to refute it, since then, neither has anyone else. Yet cosmologists and philosophers alike have proceeded as if this discovery was never made. In A World Without Time, Palle Yourgrau sets out to restore Godel to his rightful place in history, telling the story of two magnificent minds put on the shelf by the scientific fashions of their day, and attempts to rescue the brilliant work they did together.

    Science Masters Series

    The fundamental questions are answered, leaving only the details to be filled in. In this book, Dr Rupert Sheldrake, one of the world's most innovative scientists, shows that science is being constricted by assumptions that have hardened into dogmas. The 'scientific worldview' has become a belief system. All reality is material or physical. The world is a machine, made up of dead matter. Nature is purposeless. Consciousness is nothing but the physical activity of the brain. Free will is an illusion. God exists only as an idea in human minds, imprisoned within our skulls. Sheldrake examines these dogmas scientifically, and shows persuasively that science would be better off without them: freer, more interesting, and more fun.In The God Delusion Richard Dawkins used science to bash God, but here Rupert Sheldrake shows that Dawkins' understanding of what science can do is old-fashioned and itself a delusion.

    Such a device would operate under a different set of physical laws: The laws of quantum mechanics. Johnson gently leads the curious outsider through the surprisingly simple ideas needed to understand this dream, discussing the current state of the revolution, and ultimately assessing the awesome power these machines could have to change our world.

    Their pioneering work, presented here in an elegant style, challenges much of the conventional wisdom about consciousness. The Universe of Consciousness has enormous implications for our understanding of language, thought, emotion, and mental illness.

    Every technology we rely on today was created by the human mind, seeking to understand the universe around us. Scientific knowledge is our most precious possession, and our future will be shaped by the breakthroughs to come. In this personal and fascinating work, Neil Turok, Director of the Perimeter Institute for Theoretical Physics, explores the transformative scientific discoveries of the past three centuries -- from classical mechanics, to the nature of light, to the bizarre world of the quantum, and the evolution of the cosmos. Each new discovery has, over time, yielded new technologies causing paradigm shifts in the organization of society. Now, he argues, we are on the cusp of another major transformation: the coming quantum revolution that will supplant our current, dissatisfying digital age. Facing this brave new world, Turok calls for creatively re-inventing the way advanced knowledge is developed and shared, and opening access to the vast, untapped pools of intellectual talent in the developing world. Scientific research, training, and outreach are vital to our future economy, as well as powerful forces for peaceful global progress.

    Now he offers a framework for envisioning the twenty-first century--an age in which the marriage of human sensitivity and artificial intelligence fundamentally alters and improves the way we live. Kurzweil's prophetic blueprint for the future takes us through the advances that inexorably result in computers exceeding the memory capacity and computational ability of the human brain by the year 2020 (with human-level capabilities not far behind); in relationships with automated personalities who will be our teachers, companions, and lovers; and in information fed straight into our brains along direct neural pathways. Optimistic and challenging, thought-provoking and engaging, The Age of Spiritual Machines is the ultimate guide on our road into the next century.

    We nevertheless muddle through even in the absence of theories of how to act. But how do we do it?In Probably Approximately Correct, computer scientist Leslie Valiant presents a masterful synthesis of learning and evolution to show how both individually and collectively we not only survive, but prosper in a world as complex as our own. The key is “probably approximately correct” algorithms, a concept Valiant developed to explain how effective behavior can be learned. The model shows that pragmatically coping with a problem can provide a satisfactory solution in the absence of any theory of the problem. After all, finding a mate does not require a theory of mating. Valiant’s theory reveals the shared computational nature of evolution and learning, and sheds light on perennial questions such as nature versus nurture and the limits of artificial intelligence.Offering a powerful and elegant model that encompasses life’s complexity, Probably Approximately Correct has profound implications for how we think about behavior, cognition, biological evolution, and the possibilities and limits of human and machine intelligence.