The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    Enhancements to this edition include a more thorough coverage of transport processes, plus new or expanded coverage of separation process applications, fluidized beds, non-Newtonian fluids, membrane separation processes and gas-membrane theory, and much more. The book contains 240+ example problems and 550+ homework problems.

    Providing a concise introduction to abstract algebra, this work unfolds some of the fundamental systems with the aim of reaching applicable, significant results.

    All chapters have been thoroughly updated with the latest information as well as new case studies, practice questions, and exercises. This latest edition not only covers the how of clinical testing but also places greater emphasis on the what, why, and when in order to meet the needs of today's clinical laboratorians. A companion Website offers the full text online, objectives, a quiz bank, flashcards, glossary, and appendices for students and improved instructor's resources.

    Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning.The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language processing, speech recognition, computer vision, online recommendation systems, bioinformatics, and videogames. Finally, the book offers research perspectives, covering such theoretical topics as linear factor models, autoencoders, representation learning, structured probabilistic models, Monte Carlo methods, the partition function, approximate inference, and deep generative models.Deep Learning can be used by undergraduate or graduate students planning careers in either industry or research, and by software engineers who want to begin using deep learning in their products or platforms. A website offers supplementary material for both readers and instructors.

    These themes include mathematical reasoning, combinatorial analysis, discrete structures, algorithmic thinking, and enhanced problem-solving skills through modeling. Its intent is to demonstrate the relevance and practicality of discrete mathematics to all students. The Fifth Edition includes a more thorough and linear presentation of logic, proof types and proof writing, and mathematical reasoning. This enhanced coverage will provide students with a solid understanding of the material as it relates to their immediate field of study and other relevant subjects. The inclusion of applications and examples to key topics has been significantly addressed to add clarity to every subject. True to the Fourth Edition, the text-specific web site supplements the subject matter in meaningful ways, offering additional material for students and instructors. Discrete math is an active subject with new discoveries made every year. The continual growth and updates to the web site reflect the active nature of the topics being discussed. The book is appropriate for a one- or two-term introductory discrete mathematics course to be taken by students in a wide variety of majors, including computer science, mathematics, and engineering. College Algebra is the only explicit prerequisite.

    Building on two widely acclaimed previous editions, Craig Larman has updated this book to fully reflect the new UML 2 standard, to help you master the art of object design, and to promote high-impact, iterative, and skillful agile modeling practices.Developers and students will learn object-oriented analysis and design (OOA/D) through three iterations of two cohesive, start-to-finish case studies. These case studies incrementally introduce key skills, essential OO principles and patterns, UML notation, and best practices. You won’t just learn UML diagrams - you’ll learn how to apply UML in the context of OO software development.Drawing on his unsurpassed experience as a mentor and consultant, Larman helps you understand evolutionary requirements and use cases, domain object modeling, responsibility-driven design, essential OO design, layered architectures, “Gang of Four” design patterns, GRASP, iterative methods, an agile approach to the Unified Process (UP), and much more. This edition’s extensive improvements include:- A stronger focus on helping you master OOA/D through case studies that demonstrate key OO principles and patterns, while also applying the UML- New coverage of UML 2, Agile Modeling, Test-Driven Development, and refactoring- Many new tips on combining iterative and evolutionary development with OOA/D- Updates for easier study, including new learning aids and graphics- New college educator teaching resources- Guidance on applying the UP in a light, agile spirit, complementary with other iterative methods such as XP and Scrum- Techniques for applying the UML to documenting architectures- A new chapter on evolutionary requirements, and much moreApplying UML and Patterns, Third Edition, is a lucid and practical introduction to thinking and designing with objects - and creating systems that are well crafted, robust, and maintainable.

    As in the authors' bestselling "Film Art", concepts and events are illustrated with actual frame enlargements, giving students more realistic points of reference than competing books that use publicity stills.

    A six-step model offers invaluable assistance for selecting a topic, searching the literature, developing arguments, surveying the literature, critiquing the literature, and writing the literature review.

    Edited by Drs. Karen Marcdante, Robert M. Kliegman, Hal B. Jenson, and Richard E. Behrman, this edition's content was specifically developed in accordance with the 2009 curriculum guidelines of the Council on Medical Student Education in Pediatrics. It also includes many new and improved clinical photographs and images for enhanced visual reference. A user-friendly full-color format and online access via Student Consult facilitate study and expedite reference.

    It covers the main developments in the history of British and Irish literature and has extensive accompanying language notes which explore the interrelationships between language and literature. With a span from AD 600 to the present day, it emphasises the growth of literary writing, its traditions, conventions and changing characteristics, and includes literature from the margins, both geographical and cultural. Extensive quotations from poetry, prose and drama underpin the narrative.The second edition covers recent developments in literary and cultural theory and has the following features: * additional or extended material on post-colonial writers, and the literature of the 1990s* an expanded Timeline with Booker, Whitbread, and Nobel prize winners* additions to the well-received language notes which include 'Shakespeare's language', 'Reading the language of theatre and drama', 'New modes of modern writing' and 'International and rotten Englishes'* An expanded Timeline with Booker, Whitbread, and Nobel prize winners.

    It covers patient care in various clinical settings by employing a unique levels of care approach, discussing nursing implementation at multiple levels. Special features highlight the content that is most relevant and challenging for today's nursing students, including patient teaching, nutrition, drug therapy, cultural and ethnic disparities, and more.Identifies and discusses all levels of nursing management, including Health Promotion, Acute Intervention, and Ambulatory and Home Care, to prepare the nurse to effectively intervene at various stages of illness.Online podcasts feature audio key points summaries for each chapter highlighting important information.Extensive gerontologic content discusses age-related changes for each body system and alerts the nurse to differences often encountered in older patients.Attractive four-color design and over 1,400 full-color illustrations enhance learning by presenting disease processes and related anatomy and physiology more clearly.About 55 thoroughly updated, comprehensive nursing care plans incorporate current NANDA diagnoses, defining characteristics, expected outcomes, interventions with rationales, evaluation criteria, and more.New chapters on Health Disparities, Stress and Stress Management, Infection and HIV, and Nursing Management: Obesity provide a more comprehensive look at the world of medical-surgical nursing.Electronic Resource Summary at chapter openers alert students to additional electronic resources available on companion CD and Evolve.Gender Differences boxes summarize how women and men are affected differently by medical conditions.Drug Alert boxes highlight important considerations applicable to key drugs.A glossary of key terms and definitions contains definitions and page references.NCLEX examination style review questions in each chapter include a focus on prioritization of patient care.All nursing care plans now incorporate NIC and NOC. Companion CD:More than 50 interactive case studies with realistic, 3-D animations to help you visualize disease processes from the inside outA unique Stress-Busting Kit for Nursing Students with strategies for managing your (and your patients') stressA collection of Multimedia Supplements with audio and video clips, plus additional animations375 NCLEX(R) examination-style review questions

    Written expressly for "anyone who believes there are big questions out there, but does not know how to approach them," Think provides a sound framework for exploring the most basic themes of philosophy, and for understanding how major philosophers have tackled the questions that have pressed themselves most forcefully on human consciousness.

    The long-anticipated revision of this best-selling text offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence. *NEW-Nontechnical learning material-Accompanies each part of the book. *NEW-The Internet as a sample application for intelligent systems-Added in several places including logical agents, planning, and natural language. *NEW-Increased coverage of material - Includes expanded coverage of: default reasoning and truth maintenance systems, including multi-agent/distributed AI and game theory; probabilistic approaches to learning including EM; more detailed descriptions of probabilistic inference algorithms. *NEW-Updated and expanded exercises-75% of the exercises are revised, with 100 new exercises. *NEW-On-line Java software. *Makes it easy for students to do projects on the web using intelligent agents. *A unified, agent-based approach to AI-Organizes the material around the task of building intelligent agents. *Comprehensive, up-to-date coverage-Includes a unified view of the field organized around the rational decision making pa

    Jack Spielvogel's engaging, chronological narrative weaves the political, economic, social, religious, intellectual, cultural, and military aspects of history into a gripping story that is as memorable as it is instructive. Each chapter offers a substantial introduction and conclusion, providing students a context for these disparate themes. The clear narrative of a single gifted author makes it easy for students to follow the story of Western civilization. Spielvogel gives the book depth by including over 150 maps and excerpts of over 200 primary sources--including official documents, poems, and songs--that enliven the past while introducing students to source material that forms the basis of historical scholarship. Available in many split options: WESTERN CIVILIZATION, Comprehensive, 6th Edition (Chapters 1-29), ISBN: 0534646026; WESTERN CIVILIZATION, Volume I, To 1715, 6th Edition (Chapters 1-16), ISBN:0534646034; WESTERN CIVILIZATION, Volume II, Since 1500, 6th Edition (Chapters 13-29), ISBN:0534646042; WESTERN CIVILIZATION, Volume A: To 1500, 6th Edition (Chapters 1-12), ISBN: 0534646050; WESTERN CIVILIZATION, Volume B: 1300-1815, 6th Edition (Chapters 11-19), ISBN:0534646069; WESTERN CIVILIZATION, Volume C: Since 1789, 6th Edition (Chapters 19-29), ISBN: 0534646077; WESTERN CIVILIZATION, Since 1300, 6th Edition (Chapters 11-29), ISBN:0534646085.