This updated edition features new material.

    What a life and what an inspiration.' Stephen Fry__________Born in war-torn Afghanistan, Waheed Arian's earliest memories are of bombs. Fleeing the conflict with his family, he spent much of his childhood in refugee camps in Pakistan, living sometimes ten to a room without basic sanitation or access to education. After he contracted tuberculosis, his first-hand experience of the power of medicine inspired Waheed to dedicate his life to healing others. But how does a boy with nothing hope to become a doctor?Waheed largely taught himself, from textbooks bought from street-sellers, and learned English from the BBC World Service. Smuggled to the UK at fifteen with just $100 in his pocket, he found a job in a shop. He was advised to set his sights on becoming a taxi driver. But the boy from Kabul had bigger ambitions.Working through PTSD and anxiety, he studied all hours to achieve his vocation. He was accepted to read medicine at Cambridge University, Imperial College and Harvard, and went on to become a doctor in the NHS. But he wanted to do more. In 2015 he founded Arian Teleheal, a pioneering global charity that connects doctors in war zones and low-resource countries with their counterparts in the US, UK, Europe and Australia. Together, learning from each other, they save and change lives - the lives of millions of people just like Waheed.For readers of Educated and War Doctor, this is the extraordinary memoir of a boy who recognized the power of education and dreamed about helping others. It's a tale of courage, ambition and unwavering resilience in the face of all the challenges that life can throw in your way.

    

    Indeed, most are only barely aware of the diseases caused by them, except, perhaps, for mad cow disease. Yet prions are the stuff of a revolutionary science?a science that might lead to cures for some of humankind?s most devastating diseases.Fatal Flaws is a scientific detective story about this elusive protein, starting with the discovery of kuru, a disease unique to New Guinea in the 1950s that baffled scientists and carried with it whispers of cannibalism. Kuru began a scientific stampede to seek out the agent of this mysterious disease?the prion?a misfolded protein whose existence some of the world?s top scientists still find difficult to accept. Today, the subject of prions remains controversial, yet the proteins might promise new treatments for some of the most intractable brain diseases, ones that affect millions around the planet, including Parkinson?s, ALS and Alzheimer?s.In Fatal Flaws, Jay Ingram unties a complicated interweaving of biology, medicine, human tragedy, surprise and disbelief in the world of prions, and he unravels some of history?s most stunning revelations about disease, the brain and infection.

    Fat, they told us, was the enemy. Then it was salt, then sugar, then cholesterol... and on it goes. Americans listened and they lost -- but not their excess fat. What they lost was their health and waistlines. Americans are the fattest people on earth... and why? Mainly because of the food they eat. In this scientific and revolutionary book, based on Nobel Prize-winning research, medical visionary and former Massachusetts Institute of Technology researcher Dr. Barry Sears makes peak physical and mental performance, as well as permanent fat loss, simple for you to understand and achieve. With lists of good and bad carbohydrates, easy-to-follow food blocks and delicious recipes, The Zone provides all you need to begin your journey toward permanent fat loss, great health and all-round peak performance. In balance, your body will not only burn fat, but you'll fight heart disease, diabetes, PMS, chronic fatigue, depression and cancer, as well as alleviate the painful symptoms of diseases such as multiple sclerosis and HIV. This Zone state of exceptional health is well-known to champion athletes. Your own journey toward it can begin with your next meal. You will no longer think of food as merely an item of pleasure or a means to appease hunger. Food is your medicine and your ticket to that state of ultimate body balance, strength and great health: the Zone.

    What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    Explaining how, why, and when the techniques can be expected to work, the Seventh Edition places an even greater emphasis on building readers' intuition to help them understand why the techniques presented work in general, and why, in some situations, they fail. Applied problems from diverse areas, such as engineering and physical, computer, and biological sciences, are provided so readers can understand how numerical methods are used in real-life situations. The Seventh Edition has been updated and now addresses the evolving use of technology, incorporating it whenever appropriate.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    It is designed to help them understand how the disorder affects their loved ones and recognize what they can do to get off the emotional roller coasters and take care of themselves.

    Squirming parasites, bursting pustules, rotting limbs, and cascading diarrhea: it's all depicted here in vivid detail. Sometimes the remedy proved as unbearable as the sickness itself. Whether performing dire dentistry or ice-pick lobotomies, bloodletting or blistering, the medical practitioners of history were ever inventive, if not effective. Disease played a role in shaping human history, too: read how measles and smallpox hastened the decline of the native peoples of the Americas, and how typhus helped to defeat Napoleon. Extraordinary anecdotes abound, such as the cautionary tale of Typhoid Mary and how a cow called Blossom saved the day. Packed with startling medical illustrations, this morbidly fascinating study of all that ails is bound to grip you from page one and leave you reaching for the disinfectant."

    In Turing’s Cathedral, George Dyson focuses on a small group of men and women, led by John von Neumann at the Institute for Advanced Study in Princeton, New Jersey, who built one of the first computers to realize Alan Turing’s vision of a Universal Machine. Their work would break the distinction between numbers that mean things and numbers that do things—and our universe would never be the same. Using five kilobytes of memory (the amount allocated to displaying the cursor on a computer desktop of today), they achieved unprecedented success in both weather prediction and nuclear weapons design, while tackling, in their spare time, problems ranging from the evolution of viruses to the evolution of stars. Dyson’s account, both historic and prophetic, sheds important new light on how the digital universe exploded in the aftermath of World War II. The proliferation of both codes and machines was paralleled by two historic developments: the decoding of self-replicating sequences in biology and the invention of the hydrogen bomb. It’s no coincidence that the most destructive and the most constructive of human inventions appeared at exactly the same time.  How did code take over the world? In retracing how Alan Turing’s one-dimensional model became John von Neumann’s two-dimensional implementation, Turing’s Cathedral offers a series of provocative suggestions as to where the digital universe, now fully three-dimensional, may be heading next.

    Yin's bestselling text provides a complete portal to the world of case study research. With the integration of 11 applications in this edition, the book gives readers access to exemplary case studies drawn from a wide variety of academic and applied fields. Ultimately, Case Study Research and Applications will guide students in the successful design and use of the case study research method. New to this Edition Includes 11 in-depth applications that show how researchers have implemented case study methods successfully. Increases reference to relativist and constructivist approaches to case study research, as well as how case studies can be part of mixed methods projects. Places greater emphasis on using plausible rival explanations to bolster case study quality. Discusses synthesizing findings across case studies in a multiple-case study in more detail Adds an expanded list of 15 fields that have text or texts devoted to case study research. Sharpens discussion of distinguishing research from non-research case studies. The author brings to light at least three remaining gaps to be filled in the future: how rival explanations can become more routinely integrated into all case study research; the difference between case-based and variable-based approaches to designing and analyzing case studies; and the relationship between case study research and qualitative research.

    Others are sure it's the environment we experience in childhood. But could it be that many of our individual characteristics—our health, our intelligence, our temperaments—are influenced by the conditions we encountered before birth? That's the claim of an exciting and provocative field known as fetal origins. Over the past twenty years, scientists have been developing a radically new understanding of our very earliest experiences and how they exert lasting effects on us from infancy well into adulthood. Their research offers a bold new view of pregnancy as a crucial staging ground for our health, ability, and well-being throughout life.Author and journalist Annie Murphy Paul ventures into the laboratories of fetal researchers, interviews experts from around the world, and delves into the rich history of ideas about how we're shaped before birth. She discovers dramatic stories: how individuals gestated during the Nazi siege of Holland in World War II are still feeling its consequences decades later; how pregnant women who experienced the 9/11 attacks passed their trauma on to their offspring in the womb; how a lab accident led to the discovery of a common household chemical that can harm the developing fetus; how the study of a century-old flu pandemic reveals the high personal and societal costs of poor prenatal experience. Origins also brings to light astonishing scientific findings: how a single exposure to an environmental toxin may produce damage that is passed on to multiple generations; how conditions as varied as diabetes, heart disease, and mental illness may get their start in utero; why the womb is medicine's latest target for the promotion of lifelong health, from preventing cancer to reducing obesity. The fetus is not an inert being, but an active and dynamic creature, responding and adapting as it readies itself for life in the particular world it will enter. The pregnant woman is not merely a source of potential harm to her fetus, as she is so often reminded, but a source of influence on her future child that is far more powerful and positive than we ever knew. And pregnancy is not a nine-month wait for the big event of birth, but a momentous period unto itself, a cradle of individual strength and wellness and a crucible of public health and social equality.With the intimacy of a personal memoir and the sweep of a scientific revolution, Origins presents a stunning new vision of our beginnings that will change the way you think about yourself, your children, and human nature itself.

    Using the unique method he's developed that treats a type of connective tissue called the fascia, physical therapist Ming Chew has healed injuries, aches and pains that most medical professionals believe can only be fixed by medication and surgery. The Ming Method uses simple stretches and exercises, a supplementation and hydration plan, and an anti-inflammatory diet to release the fascia and banish pain forever--quickly, safely and drug-free.

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.