The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    Librarian note: an alternate cover for this edition can be found here.Michel Foucault examines the archeology of madness in the West from 1500 to 1800 – from the late Middle Ages, when insanity was still considered part of everyday life and fools and lunatics walked the streets freely, to the time when such people began to be considered a threat, asylums were first built, and walls were erected between the “insane” and the rest of humanity.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    Now considered a classic, this fascinating personal odyssey and revealing public reflection on American sexuality changed the way Americans looked at themselves and one another.From the Paperback edition.

    Fisher searches for the traces of these lost futures in the work of David Peace, John Le Carré, Christopher Nolan, Joy Division, Burial and many others.

    But what if science itself can’t be relied on?Medicine, education, psychology, health, parenting – wherever it really matters, we look to science for advice. Science Fictions reveals the disturbing flaws that undermine our understanding of all of these fields and more.While the scientific method will always be our best and only way of knowing about the world, in reality the current system of funding and publishing science not only fails to safeguard against scientists’ inescapable biases and foibles, it actively encourages them. From widely accepted theories about ‘priming’ and ‘growth mindset’ to claims about genetics, sleep, microbiotics, as well as a host of drugs, allergies and therapies, we can trace the effects of unreliable, overhyped and even fraudulent papers in austerity economics, the anti-vaccination movement and dozens of bestselling books – and occasionally count the cost in human lives.Stuart Ritchie was among the first people to help expose these problems. In this vital investigation, he gathers together the evidence of their full and shocking extent – and how a new reform movement within science is fighting back. Often witty yet deadly serious, Science Fictions is at the vanguard of the insurgency, proposing a host of remedies to save and protect this most valuable of human endeavours from itself.

    Our society now embraces sharing like never before: time alone is being forced out of our lives by the constant pings of smartphones and prods of social media. But what if solitude still has something to offer us - something we have forgotten, but that we still desperately need? In Solitude, award-winning author Michael Harris examines why being alone matters now more than ever before. He reflects on the paradoxical feeling of isolation that emerges from being constantly connected - and on how learning the beauty of solitude can help us escape it. After all, it is when we are alone that we realise the greatest truths about ourselves. Being alone - really alone - could be the only antidote to the frenzy of our digital age. Rich with stories about the transformative power of solitude, and drawing on the research of the world's leading neuroscientists and behavioural psychologists, Solitude offers a timely and profound exploration of how to be alone - and why it matters for us all.

    In this ground-breaking investigation, Laura Bates traces the roots of misogyny across a complex spider's web of groups extending from Men's Rights Activists and Pick up Artists to "Men Going their Own Way" trolls and the Incel movement, in the name of which some men have committed terrorist acts. Drawing parallels with other extremist movements around the world, Bates seeks to understand what attracts men to the movement, how it grooms and radicalizes boys, how it operates, and what can be done to stop it. Most urgently of all, she traces the pathways this extreme ideology has taken from the darkest corners of the internet to emerge covertly in our mainstream media, our playgrounds, and our parliament. Going undercover online and off, Bates provides the first, comprehensive look at this hitherto under-the-radar phenomenon, including fascinating interviews with trolls, former incels, the academics studying this movement, and the men fighting back.

    Trump, journalist Seyward Darby went looking for the women of the so-called alt-right--really just white nationalism with a new label. The mainstream media depicted the alt-right as a bastion of angry white men, but was it? As women headlined resistance to the Trump administration's bigotry and sexism, most notably at the women's marches, Darby wanted to know why others were joining a movement espousing racism and anti-feminism. Who were these women, and what did their activism reveal about America's past, present, and future? Darby researched dozens of women across the country before settling on three: Corinna Olsen, Ayla Stewart, and Lana Lokteff. Each was born in 1979 and became a white nationalist in the post-9/11 era. Their respective stories of radicalization upend much of what we assume about women, politics, and political extremism.

    Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.

    The new nanny gives a mother an uneasy feeling. A stranger in a deserted parking lot offers unsolicited help. The threat of violence surrounds us every day. But we can protect ourselves, by learning to trust—and act on—our gut instincts.In this empowering book, Gavin de Becker, the man Oprah Winfrey calls the nation's leading expert on violent behavior, shows you how to spot even subtle signs of danger—before it's too late. Shattering the myth that most violent acts are unpredictable, de Becker, whose clients include top Hollywood stars and government agencies, offers specific ways to protect yourself and those you love, including how to act when approached by a stranger, when you should fear someone close to you, what to do if you are being stalked, how to uncover the source of anonymous threats or phone calls, the biggest mistake you can make with a threatening person, and more. Learn to spot the danger signals others miss. It might just save your life.

    It would not stop there. Before long, the business had turned into a sprawling multinational conglomerate engaged in almost every conceivable aspect of criminal mayhem. Yachts carrying $100 million in cocaine. Safe houses in Hong Kong filled with gold bars. Shipments of methamphetamine from North Korea. Weapons deals with Iran. Mercenary armies in Somalia. Teams of hitmen in the Philippines. Encryption programs so advanced that the government could not break them.The man behind it all, pulling the strings from a laptop in Manila, was Paul Calder Le Roux—a reclusive programmer turned criminal genius who could only exist in the networked world of the twenty-first century, and the kind of self-made crime boss that American law enforcement had never imagined.For half a decade, DEA agents played a global game of cat-and-mouse with Le Roux as he left terror and chaos in his wake. Each time they came close, he would slip away. It would take relentless investigative work, and a shocking betrayal from within his organization, to catch him. And when he was finally caught, the story turned again, as Le Roux struck a deal to bring down his own organization and the people he had once employed.Award-winning investigative journalist Evan Ratliff spent four years piecing together this intricate puzzle, chasing LeRoux's empire and his shadowy henchmen around the world, conducting hundreds of interviews and uncovering thousands of documents. The result is a riveting, unprecedented account of a crime boss built by and for the digital age.Advance praise for The Mastermind“As directors, we spend countless hours imagining heightened plots and memorable characters that will leave a lasting impression on audiences. The true tale of obsession, genius, intrigue, and vengeance detailed in The Mastermind is as gripping and cinematic as anything we could endeavor to conjure up.”—Joe and Anthony Russo, directors of Captain America: The Winter Soldier, Captain America: Civil War, and Avengers: Infinity War“With his relentless and fearless reporting, Evan Ratliff has pried open a hidden world filled with high-tech gangsters and drug kingpins and double-crossers and stone-cold hitmen. The story is as fascinating as it is terrifying, and it is one that will hold you in its grip.”—David Grann, author of Killers of the Flower Moon“If truth is stranger than fiction, then The Mastermind is the truest book you’ll read this year. The only thing predictable about it is how quickly you’ll turn the pages.”—Noah Hawley, author of Before the Fall and creator of the TV series Fargo “This is a mesmerizing, absolutely bonkers story about a man as brilliant as he is villainous. You’ll find yourself sucked in, freaked out, and ultimately blown away by Ratliff's storytelling and tireless reporting. The Mastermind is a masterpiece.”—Nick Thompson, editor-in-chief, Wired

    Despite a mountain of circumstantial evidence against him, he proclaims his innocence. The case takes a twist when Nina’s former lover, and Hans’s former best friend, Sean Sturgeon, confesses to eight unrelated murders that no one has ever heard of.At the time of Sturgeon’s confession, Stephen Elliot is paralyzed by writer’s block, in the thrall of Adderall dependency, and despondent over the state of his romantic life. But he is fascinated by Sturgeon, whose path he has often crossed in San Francisco’s underground S&M scene. What kind of person, he wonders, confesses to a murder he likely did not commit? One answer is, perhaps, a man like Elliott’s own father.So begins a riveting journey through a neon landscape of false confessions, self-medication, and torturous sex. Set against the backdrop of a nation at war, in the declining years of the Silicon Valley tech boom and the dawn of Paris Hilton’s celebrity, The Adderall Diaries is at once a gripping account of a murder trial and a scorching investigation of the self. Tough, tender, and unflinchingly honest, it is the breakout book by one of the most daring writers of his generation.

    This staggering amount of information—unprecedented in history—can tell us a great deal about who we are—the fears, desires, and behaviors that drive us, and the conscious and unconscious decisions we make. From the profound to the mundane, we can gain astonishing knowledge about the human psyche that less than twenty years ago, seemed unfathomable.Everybody Lies offers fascinating, surprising, and sometimes laugh-out-loud insights into everything from economics to ethics to sports to race to sex, gender and more, all drawn from the world of big data. What percentage of white voters didn’t vote for Barack Obama because he’s black? Does where you go to school effect how successful you are in life? Do parents secretly favor boy children over girls? Do violent films affect the crime rate? Can you beat the stock market? How regularly do we lie about our sex lives and who’s more self-conscious about sex, men or women?Investigating these questions and a host of others, Seth Stephens-Davidowitz offers revelations that can help us understand ourselves and our lives better. Drawing on studies and experiments on how we really live and think, he demonstrates in fascinating and often funny ways the extent to which all the world is indeed a lab. With conclusions ranging from strange-but-true to thought-provoking to disturbing, he explores the power of this digital truth serum and its deeper potential—revealing biases deeply embedded within us, information we can use to change our culture, and the questions we’re afraid to ask that might be essential to our health—both emotional and physical. All of us are touched by big data everyday, and its influence is multiplying. Everybody Lies challenges us to think differently about how we see it and the world.

    Then came SuperFreakonomics, a documentary film, an award-winning podcast, and more.Now, with Think Like a Freak, Steven D. Levitt and Stephen J. Dubner have written their most revolutionary book yet. With their trademark blend of captivating storytelling and unconventional analysis, they take us inside their thought process and teach us all to think a bit more productively, more creatively, more rationally—to think, that is, like a Freak.Levitt and Dubner offer a blueprint for an entirely new way to solve problems, whether your interest lies in minor lifehacks or major global reforms. As always, no topic is off-limits. They range from business to philanthropy to sports to politics, all with the goal of retraining your brain. Along the way, you’ll learn the secrets of a Japanese hot-dog-eating champion, the reason an Australian doctor swallowed a batch of dangerous bacteria, and why Nigerian e-mail scammers make a point of saying they’re from Nigeria.Some of the steps toward thinking like a Freak:First, put away your moral compass—because it’s hard to see a problem clearly if you’ve already decided what to do about it.Learn to say “I don’t know”—for until you can admit what you don’t yet know, it’s virtually impossible to learn what you need to.Think like a child—because you’ll come up with better ideas and ask better questions.Take a master class in incentives—because for better or worse, incentives rule our world.Learn to persuade people who don’t want to be persuaded—because being right is rarely enough to carry the day.Learn to appreciate the upside of quitting—because you can’t solve tomorrow’s problem if you aren’t willing to abandon today’s dud.Levitt and Dubner plainly see the world like no one else. Now you can too. Never before have such iconoclastic thinkers been so revealing—and so much fun to read.