It treats the subject as a coherent whole, complete with numerous logical connections, consequences, and an underlying structure and language. Employing an approach based on mechanism and reaction type, the book empasizes understanding ideas rather than merely memorizing facts. It shows students how to realistically draw molecules and mechanisms to reveal the fundamental chemistry.Using a fresh, accessible writing style as well as examples from everyday life, the authors explain the basics of organic chemistry carefully and thoroughly. A special focus on mechanism, orbitals, and stereochemistry helps students gain a solid comprehension of important factors common to all reactions. The book's innovative design enhances clarity and instruction with boxes that separate summary information and other material from the main text; a variety of colors that draw attention to items such as atoms, molecules, and orbitals; and figures that are drawn in red with significant parts emphasized in black. Early chapters feature carbonyl group reactions, and later chapters systematically develop the chemistry through discussions of spectroscopy, stereochemistry, and chemical reactions.Each chapter opens with a Connections box, divided into three columns:- Building on: Details material from previous chapters that relate to the current chapter- Arriving at: Provides a guide to the content of the chapter- Looking forward to: Previews later chapters, which develop and expand the current material

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Pure Substances, The First And Second Laws, Gases, Psychrometrics, The Vapor, Gas And Refrigeration Cycles, Heat Transfer, Compressible Flow, Chemical Reactions, Fuels, And More Are Presented In Detail And Enhanced With Practical Applications. This Version Presents The Material Using SI Units And Has Ample Material On SI Conversion, Steam Tables, And A Mollier Diagram. A CD-ROM, Included With The Print Version Of The Text, Includes A Fully Functional Version Of Quickfield (Widely Used In Industry), As Well As Numerous Demonstrations And Simulations With MATLAB, And Other Third Party Software.

    Enhancements to this edition include a more thorough coverage of transport processes, plus new or expanded coverage of separation process applications, fluidized beds, non-Newtonian fluids, membrane separation processes and gas-membrane theory, and much more. The book contains 240+ example problems and 550+ homework problems.

    Why is glass see-through? What makes elastic stretchy? Why does a paper clip bend? Why does any material look and behave the way it does? These are the sorts of questions that Mark Miodownik a globally-renowned materials scientist has spent his life exploring In this book he examines the materials he encounters in a typical morning, from the steel in his razor and the graphite in his pencil to the foam in his sneakers and the concrete in a nearby skyscraper.

    The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    The bestselling textbook inorganic chemistry text on the market covers both theoretical and descriptive aspects of the subject, and emphasizes experimental methods, industrial applications, and modern topics.

    It provides up to date information on structural properties, the processing of materials and their applications.

    They will enable you to sculpt your body while improving your flexibility and sense of well-being. The results are visible after only a few sessions.

    Enjoy a thrilling intergalactic tour as Andrew Thomas redefines the force of gravity and introduces a brave new view of the universe!

    Starting once again with fossils, he turns his gaze skyward, showing us how the entirety of the universe’s fourteen-billion-year history can be seen in our bodies. As he moves from our very molecular composition (a result of stellar events at the origin of our solar system) through the workings of our eyes, Shubin makes clear how the evolution of the cosmos has profoundly marked our own bodies. Fully illustrated with black and white drawings.

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

    It is within the realm of possibility that their work may usher in a change in global economics as profound as the Industrial Revolution. As may be expected, press reports dealing with asteroid mining have been numerous, ranging in scope from short and breezy to broad and serious, and in quality from accurate to impressionistic to simply uninformed. There is good reason to be curious about what may be the biggest game-changer in human economic history. And there is good reason to look closely at the underlying science and engineering that form the foundation of this work.

    This new model replaces the popular D5000 and creates a nice bridge between the more beginner-level D3100 and the high-end D7000.This book has one goal: to teach D5100 owners how to make great shots using their new Nikon camera. Users learn how to use the D5100 to create the type of photos that inspired them to buy the camera in the first place. Everything in the book is in service of creating a great image.Starting with the top ten things users need to know about the camera, photographer Rob Sylvan carefully guides readers through the operating features. Owners get practical advice from a pro on which settings to use when, great shooting tips, and even end-of-chapter assignments.

    It provides many detailed, practical design and analysis examples intended to relate theory to the workplace. Chapter topics include first experiences with an op amp; inverting and noninverting amplifiers; comparators and controls; selected applications of op amps; signal generators; op amps with diodes; differential, instrumentation, and bridge amplifiers; DC performance: bias, offsets, and drift; AC performance: bandwidth, slew rate, noise; active filters; modulating, demodulating, and frequency changing with the multiplier; integrated-circuit timers; digital-to-analog converters; analog-to-digital converters; and power supplies. For design engineers rs