But it’s also messy, fallible, and about 50,000 years out of date. We cling to superstitions, remember faces but not names, miss things sitting right in front of us, and lie awake at night while our brains endlessly replay our greatest fears. Idiot Brain is for anyone who has ever wondered why their brain appears to be sabotaging their life—and what on earth it is really up to.A Library Journal Science Bestseller and a Finalist for the Goodreads Choice Award in Science Technology.

    This is the story of two men who first become friends in 1970s New York, of the women in their lives, of their sons, born the same year, and of how relations between the two families become strained, first by tragedy, then by a monstrous duplicity which comes slowly and corrosively to the surface.

    Boyle transforms two real people from the pages of American history into rich mythic creations whose tortured love and epic story is intimate enough to break our hearts.Boyle anchors his unforgettable tale with the remarkable and courageous Katherine Dexter. Her husband, Stanley McCormick, thirty-one-year-old son of the millionaire inventor of the Reaper, has become schizophrenic and a sexual maniac. Stanley is locked up in his Santa Barbara mansion and forbidden the mere sight of women — above all, his wife. Throughout her career as a scientist and suffragette, Katherine's faith never wavers: that, one day, one of the many psychiatrists she hires to try to cure her husband will free him of his demons.One of America's most imaginative contemporary novelists, Boyle weaves his hallmark virtuoso prose into a masterful epic. Textured with his acclaimed humor, versatility, and imagination, Riven Rock is his most fully realized and compassionate novel to date.

    Pat has a theory: his life is a movie produced by God. And his God-given mission is to become physically fit and emotionally literate, whereupon God will ensure a happy ending for him—the return of his estranged wife, Nikki. (It might not come as a surprise to learn that Pat has spent time in a mental health facility.) The problem is, Pat's now home, and everything feels off. No one will talk to him about Nikki; his beloved Philadelphia Eagles keep losing; he's being pursued by the deeply odd Tiffany; his new therapist seems to recommend adultery as a form of therapy. Plus, he's being hunted by Kenny G!In this enchanting novel, Matthew Quick takes us inside Pat's mind, showing us the world from his distorted yet endearing perspective. As the award-winning novelist Justin Cronin put it: "Tender, soulful, hilarious, and true, The Silver Linings Playbook is a wonderful debut."

    Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?In a swift and breathtaking narrative, Cahalan tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that nearly didn’t happen.

    Meet Martin, JJ, Jess, and Maureen. Four people who come together on New Year's Eve: a former TV talk show host, a musician, a teenage girl, and a mother. Three are British, one is American. They encounter one another on the roof of Topper's House, a London destination famous as the last stop for those ready to end their lives. In four distinct and riveting first-person voices, Nick Hornby tells a story of four individuals confronting the limits of choice, circumstance, and their own mortality. This is a tale of connections made and missed, punishing regrets, and the grace of second chances. Intense, hilarious, provocative, and moving, A Long Way Down is a novel about suicide that is, surprisingly, full of life. What's your jumping-off point? MaureenWhy is it the biggest sin of all? All your life you're told that you'll be going to this marvelous place when you pass on. And the one thing you can do to get you there a bit quicker is something that stops you getting there at all. Oh, I can see that it's a kind of queue-jumping. But if someone jumps the queue at the post office, people tut. Or sometimes they say "Excuse me, I was here first." They don't say "You will be consumed by hellfire for all eternity." That would be a bit strong. MartinI'd spent the previous couple of months looking up suicides on the Internet, just out of curiosity. And nearly every single time, the coroner says the same thing: "He took his own life while the balance of his mind was disturbed." And then you read the story about the poor bastard: His wife was sleeping with his best friend, he'd lost his job, his daughter had been killed in a road accident some months before . . . Hello, Mr. Coroner? I'm sorry, but there's no disturbed mental balance here, my friend. I'd say he got it just right. JessI was at a party downstairs. It was a shit party, full of all these ancient crusties sitting on the floor drinking cider and smoking huge spliffs and listening to weirdo space-out reggae. At midnight, one of them clapped sarcastically, and a couple of others laughed, and that was it-Happy New Year to you, too. You could have turned up to that party as the happiest person in London, and you'd still have wanted to jump off the roof by five past twelve. And I wasn't the happiest person in London anyway. Obviously. JJNew Year's Eve was a night for sentimental losers. It was my own stupid fault. Of course there'd be a low-rent crowd up there. I should have picked a classier date-like March 28, when Virginia Woolf took her walk into the river, or November 25 (Nick Drake). If anybody had been on the roof on either of those nights, the chances are they would have been like-minded souls, rather than hopeless f*ck-ups who had somehow persuaded themselves that the end of a calendar year is in any way significant.

    S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

    Fight Club’s estranged narrator leaves his lackluster job when he comes under the thrall of Tyler Durden, an enigmatic young man who holds secret after-hours boxing matches in the basement of bars. There, two men fight "as long as they have to." This is a gloriously original work that exposes the darkness at the core of our modern world.

    That he emerged to write this funny and true book and then moved on to find the meaningful life that for a while had seemed beyond reach is what ultimately happens in The Eden Express. But the real story here is that throughout his harrowing experience his sense of humor let him see the humanity of what he was going through, and his gift of language let him describe it in such a moving way that others could begin to imagine both its utter ordinariness as well as the madness we all share.

    But behind her seemingly flawless façade lay a dangerous secret—for the better part of her life Cheney had been battling debilitating bipolar disorder and concealing a pharmacy's worth of prescriptions meant to stabilize her moods and make her "normal."In bursts of prose that mirror the devastating highs and extreme lows of her illness, Cheney describes her roller-coaster life with shocking honesty—from glamorous parties to a night in jail; from flying fourteen kites off the edge of a cliff in a thunderstorm to crying beneath her office desk; from electroshock therapy to a suicide attempt fueled by tequila and prescription painkillers.With Manic, Cheney gives voice to the unarticulated madness she endured. The clinical terms used to describe her illness were so inadequate that she chose to focus instead on her own experience, in her words, "on what bipolar disorder felt like inside my own body." Here the events unfold episodically, from mood to mood, the way she lived and remembers life. In this way the reader is able to viscerally experience the incredible speeding highs of mania and the crushing blows of depression, just as Cheney did. Manic does not simply explain bipolar disorder—it takes us in its grasp and does not let go.In the tradition of Darkness Visible and An Unquiet Mind, Manic is Girl, Interrupted with the girl all grown up. This harrowing yet hopeful book is more than just a searing insider's account of what it's really like to live with bipolar disorder. It is a testament to the sharp beauty of a life lived in extremes.

    He was told—like his entire generation—that his problem was caused by a chemical imbalance in his brain. As an adult, trained in the social sciences, he began to investigate this question—and he learned that almost everything we have been told about depression and anxiety is wrong. Across the world, Hari discovered social scientists who were uncovering the real causes—and they are mostly not in our brains, but in the way we live today. Hari’s journey took him from the people living in the tunnels beneath Las Vegas, to an Amish community in Indiana, to an uprising in Berlin—all showing in vivid and dramatic detail these new insights. They lead to solutions radically different from the ones we have been offered up until now.Just as Chasing the Scream transformed the global debate about addiction, with over twenty million views for his TED talk and the animation based on it, Lost Connections will lead us to a very different debate about depression and anxiety—one that shows how, together, we can end this epidemic.

    Yet when left alone for a few days by his brother, he struggles with his overwhelming desire for alcohol, succumbs to it and, in the resulting prolonged agony, goes over much of his life up to and including the lost weekend.

    A neurologist's insightful and compassionate look into the misunderstood world of psychosomatic disorders, told through individual case histories

    With a muckraker's passion, Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. Tracing over three centuries of "cures" for madness, Whitaker shows how medical therapies have been used to silence patients and dull their minds. He tells of the eighteenth- and nineteenth-century practices of "spinning" the insane, extracting their teeth, ovaries, and intestines, and submerging patients in freezing water. The "cures" in the 1920s and 1930s were no less barbaric as eugenic attitudes toward the mentally ill led to brain-damaging lobotomies and electroshock therapy. Perhaps Whitaker's most damning revelation, however, is his report of how drug companies in the 1980s and 1990s skewed their studies in an effort to prove the effectiveness of their products. Based on exhaustive research culled from old patient medical records, historical accounts, numerous interviews, and hundreds of government documents, Mad in America raises important questions about our obligations to the mad, what it means to be "insane," and what we value most about the human mind.

    Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress.As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear--and the ones that plague us now--are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way--through fighting or fleeing. Over time, this activation of a stress response makes us sick.