He was sleek and prosperous, with a dainty goatee. Though he smiled reassuringly, the poet noticed that he kept a safe distance. In a soothing, urbane voice, the physician explained the treatment: stewed prunes to evacuate the bowels; succulent meats to ease digestion; cinnabar and the sweating tub to cleanse the disease from the skin. The doctor warned of minor side effects: uncontrolled drooling, fetid breath, bloody gums, shakes and palsies. Yet desperate diseases called for desperate remedies, of course.Were Shakespeare's shaky handwriting, his obsession with venereal disease, and his premature retirement connected? Did John Milton go blind from his propaganda work for the Puritan dictator Oliver Cromwell, as he believed, or did he have a rare and devastating complication of a very common eye problem? Did Jonathan Swift's preoccupation with sex and filth result from a neurological condition that might also explain his late-life surge in creativity? What Victorian plague wiped out the entire Brontë family? What was the cause of Nathaniel Hawthorne's sudden demise? Were Herman Melville's disabling attacks of eye and back pain the product of "nervous affections," as his family and physicians believed, or did he actually have a malady that was unknown to medical science until well after his death? Was Jack London a suicide, or was his death the product of a series of self-induced medical misadventures? Why did W. B. Yeats's doctors dose him with toxic amounts of arsenic? Did James Joyce need several horrific eye operations because of a strange autoimmune disease acquired from a Dublin streetwalker? Did writing Nineteen Eighty-Four actually kill George Orwell? The Bard meets House, M.D. in this fascinating untold story of the impact of disease on the lives and works of some the finest writers in the English language. In Shakespeare's Tremor and Orwell's Cough, John Ross cheerfully debunks old biographical myths and suggests fresh diagnoses for these writers' real-life medical mysteries. The author takes us way back, when leeches were used for bleeding and cupping was a common method of cure, to a time before vaccinations, sterilized scalpels, or real drug regimens. With a healthy dose of gross descriptions and a deep love for the literary output of these ten greats, Ross is the doctor these writers should have had in their time of need.

    This title is suitable for students preparing for careers in medicine, dentistry, nursing, and allied health, as well as research, teaching, and industry.

    Beautifully presented, it introduces the formation and function of blood cells and diseases that arise from dysfunction and disruption of these processes. Basic science, diagnostic tests and clinical features and management are all easily explained. The 5th edition has been reorganized to increase the focus on discrete disorders to show the increased understanding of the causation of blood disorders and improved diagnostic techniques and clinical management. A new standardized approach to describing disease and management has also been introduced. The authors' engaging style and inviting presentation continue to make Essential Haematology the perfect learning and reference text.Fully supported with downloadable figures from the book, along with a PDF of the captions, at www.wiley.com/go/essentialhaematology

    He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.In Ravenous, Sam Apple reclaims Otto Warburg as a forgotten, morally compromised genius who pursued cancer single-mindedly even as Europe disintegrated around him. While the vast majority of Jewish scientists fled Germany in the anxious years leading up to World War II, Warburg remained in Berlin, working under the watchful eye of the dictatorship. With the Nazis goose-stepping their way across Europe, systematically rounding up and murdering millions of Jews, Warburg awoke each morning in an elegant, antiques-filled home and rode horses with his partner, Jacob Heiss, before delving into his research at the Kaiser Wilhelm Society.Hitler and other Nazi leaders, Apple shows, were deeply troubled by skyrocketing cancer rates across the Western world, viewing cancer as an existential threat akin to Judaism or homosexuality. Ironically, they viewed Warburg as Germany’s best chance of survival. Setting Warburg’s work against the absorbing history of cancer science, Apple follows him as he arrived at his central belief that cancer is a problem of metabolism. Though Warburg’s metabolic approach to cancer was considered groundbreaking, his work was soon eclipsed in the early postwar era, after the discovery of the structure of DNA set off a search for the genetic origins of cancer.Remarkably, Warburg’s theory has undergone a resurgence in our own time, as scientists have begun to investigate the dangers of sugar and the link between obesity and cancer, finding that the way we eat can influence how cancer cells take up nutrients and grow. Rooting his revelations in extensive archival research as well as dozens of interviews with today’s leading cancer authorities, Apple demonstrates how Warburg’s midcentury work may well hold the secret to why cancer became so common in the modern world and how we can reverse the trend. A tale of scientific discovery, personal peril, and the race to end a disastrous disease, Ravenous would be the stuff of the most inventive fiction were it not, in fact, true.

    And if we exercise and cut carbs, we'll lose more weight. Right? Wrong. In this paradigm-shifting book, Herman Pontzer reveals for the first time how human metabolism really works so that we can finally manage our weight and improve our health.Pontzer's groundbreaking studies with hunter-gatherer tribes show how exercise doesn't increase our metabolism. Instead, we burn calories within a very narrow range: nearly 3,000 calories per day, no matter our activity level. This was a brilliant evolutionary strategy to survive in times of famine. Now it seems to doom us to obesity. The good news is we can lose weight, but we need to cut calories. Refuting such weight-loss hype as paleo, keto, anti-gluten, anti-grain, and even vegan, Pontzer discusses how all diets succeed or fail: For shedding pounds, a calorie is a calorie.At the same time, we must exercise to keep our body systems and signals functioning optimally, even if it won't make us thinner. Hunter-gatherers like the Hadza move about five hours a day and remain remarkably healthy into old age. But elite athletes can push the body too far, burning calories faster than their bodies can take them in. It may be that the most spectacular athletic feats are the result not just of great training, but of an astonishingly efficient digestive system.Revealing, irreverent, and always entertaining, Pontzer has written a book that will change how you eat, move, and live.

    Enthusiastic and informal accounts of the exciting discoveries and fascinating observations made by naturalists in the study of the behavior of animals in their natural surroundings

    With microscopes and brain scans, with psychological experiments and breakthroughs in genetics, neuroscientists are developing new theories about every aspect of our minds from the nature of consciousness to the causes of disorders like autism and schizophrenia. In Brain Cuttings, award-winning science writer Carl Zimmer takes readers on fascinating explorations of the frontiers of research, shedding light on our innermost existence the speed of thought, our perception of time, the complex flashes of electricity that give rise to fear and love, and more.

    Book by Naam, Ramez

      Everything—from biological life to inanimate systems—generates shape and structure and evolves in a sequence of ever-improving designs in order to facilitate flow. River basins, cardiovascular systems, and bolts of lightning are very efficient flow systems to move a current—of water, blood, or electricity. Likewise, the more complex architecture of animals evolve to cover greater distance per unit of useful energy, or increase their flow across the land. Such designs also appear in human organizations, like the hierarchical "flowcharts" or reporting structures in corporations and political bodies. All are governed by the same principle, known as the Constructal Law, and configure and reconfigure themselves over time to flow more efficiently. Written in an easy style that achieves clarity without sacrificing complexity, Design in Nature is a paradigm-shifting book that will fundamentally transform our understanding of the world around us.

    Learners develop useful and relevant vocabulary while exploring and expanding critical thinking skills.

    In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of forty trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast: her groundbreaking experiments with mouse, human, and artificial embryo models give hope to how more women can sustain viable pregnancies. Set at the intersection of science's greatest powers and humanity's greatest concern, The Dance of Life is a revelatory account of the future of fertility -- and life itself.

    An examination of resultant forces and resolved components, systematic analysis of trusses, moment of inertia calculation, velocity ratio and various types of motion in dynamics are among the topics discussed.

    We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    Marieb draws on her own, unique experience as a full-time A&P professor and part-time nursing student to explain concepts and processes in a meaningful and memorable way. With the Seventh Edition, Dr. Marieb has teamed up with co-author Katja Hoehn to produce the most exciting edition yet, with beautifully-enhanced muscle illustrations, updated coverage of factual material and topic boxes, new coverage of high-interest topics such as Botox, designer drugs, and cancer treatment, and a comprehensive instructor and student media package. Package Components *NEW! InterActive Physiology(R) 9-System Suite CD-ROM *Student Access Kit for MyA&P (CourseCompass) and the Anatomy & Physiology Place companion website *REVISED! A Brief Atlas of the Human Body, Second Edition

    Ellen Datlow and Terri Windling continue their critically acclaimed and award-winning tradition with another stunning collection of stories. The fiction and poetry here is culled from an exhaustive survey of the field, nearly four dozen stories ranging from fairy tales to gothic horror, from magical realism to dark tales in the Grand Guignol style. Rounding out the volume are the editors' invaluable overviews of the year in fantasy and horror, a new Year's Best section, on comics, by Charles Vess, and on anime and manga, by Joan D. Vinge, and a long list of Honorable Mentions, making this an indispensable reference as well as the best reading available in fantasy and horror.