Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

    Once the epicenter of the voting rights struggle, today it's Ground Zero for a new movement that is Flowers's life's work. It's a fight to ensure human dignity through a right most Americans take for granted: basic sanitation. Too many people, especially the rural poor, lack an affordable means of disposing cleanly of the waste from their toilets, and, as a consequence, live amid filth.Flowers calls this America's dirty secret. In this powerful book she tells the story of systemic class, racial, and geographic prejudice that foster Third World conditions, not just in Alabama, but across America, in Appalachia, Central California, coastal Florida, Alaska, the urban Midwest, and on Native American reservations in the West.Flowers's book is the inspiring story of the evolution of an activist, from country girl to student civil rights organizer to environmental justice champion at Bryan Stevenson's Equal Justice Initiative. It shows how sanitation is becoming too big a problem to ignore as climate change brings sewage to more backyards, and not only those of poor minorities.

    Learn how to identify the strategies and the dosages for using food to transform your resilience and health in EAT TO BEAT DISEASE.We have radically underestimated our body's power to transform and restore our health. Pioneering physician scientist, Dr. William Li, empowers readers by showing them the evidence behind over 200 health-boosting foods that can starve cancer, reduce your risk of dementia, and beat dozens of avoidable diseases. EAT TO BEAT DISEASE isn't about what foods to avoid, but rather is a life-changing guide to the hundreds of healing foods to add to your meals that support the body's defense systems, including:PlumsCinnamonJasmine teaRed wine and beerBlack BeansSan Marzano tomatoesOlive oilPacific oystersCheeses like Jarlsberg, Camembert and cheddarSourdough breadThe book's plan shows you how to integrate the foods you already love into any diet or health plan to activate your body's health defense systems-Angiogenesis, Regeneration, Microbiome, DNA Protection, and Immunity-to fight cancer, diabetes, cardiovascular, neurodegenerative, and autoimmune diseases, and other debilitating conditions.Both informative and practical, EAT TO BEAT DISEASE explains the science of healing and prevention, the strategies for using food to actively transform health, and points the science of well-being and disease prevention in an exhilarating new direction.

    Their book The Pact and their work through the Three Doctors Foundation have inspired countless young men and women to strive for goals they otherwise would not have dreamed they could attain. In this book, Dr. Davis looks at the healthcare crisis in the inner city from a rare perspective: as a doctor who works on the front line of emergency medical care in the community where he grew up, and as a member of that community who has faced the same challenges as the people he treats every day. He also offers invaluable practical advice for those living in such communities, where conditions like asthma, heart disease, stroke, obesity, and AIDS are disproportionately endemic.Dr. Davis’s sister, a drug addict, died of AIDS; his brother is now paralyzed and confined to a wheelchair as a result of a bar fight; and he himself did time in juvenile detention—a wake-up call that changed his life. He recounts recognizing a young man who is brought to the E.R. with critical gunshot wounds as someone who was arrested with him when he was a teenager during a robbery gone bad; describes a patient whose case of sickle-cell anemia rouses an ethical dilemma; and explains the difficulty he has convincing his landlord and friend, an older woman, to go to the hospital for much-needed treatment. With empathy and hard-earned wisdom, Living and Dying in Brick City presents an urgent picture of medical care in our cities. It is an important resource guide for anyone at risk, anyone close to those at risk, and anyone who cares about the fate of our cities.

    The top-selling CS review book written by students and IMGs who recently passed 100+ high-yield minicases by chief complaint 30 complete cases simulate the exam experience Contains new Patient Encounters, including telephone interviews Perfect for group or solo study YOUR COMPLETE CS SURVIVAL GUIDE FROM THE AUTHORS OF FIRST AID FOR THE USMLE STEP 1 INSIDER ADVICE FOR STEP 2 CS SUCCESS New miniguide shows US students and IMGs how best to use this book Revised by test veterans to reflect the 2005--2006 exam experience Each complete case features standardized patient checklists and a recommended clinical approach Minicases represent the major chief complaints and diagnoses seen on the Step 2 CS Proven strategies for the patient encounter and patient note High-yield, must-know facts on patient diagnosis and workup.

    Description:- When Breath Becomes Air At the age of thirty-six, on the verge of completing a decade’s training as a neurosurgeon, Paul Kalanithi was diagnosed with inoperable lung cancer. One day he was a doctor treating the dying, the next he was a patient struggling to live. When Breath Becomes Air chronicles Kalanithi’s transformation from a medical student asking what makes a virtuous and meaningful life into a neurosurgeon working in the core of human identity – the brain – and finally into a patient and a new father. Being Mortal: Illness, Medicine and What Matters in the End For most of human history, death was a common, ever-present possibility. It didn't matter whether you were five or fifty - every day was a roll of the dice. But now, as medical advances push the boundaries of survival further each year, we have become increasingly detached from the reality of being mortal. So here is a book about the modern experience of mortality - about what it's like to get old and die, how medicine has changed this and how it hasn't, where our ideas about death have gone wrong. With his trademark mix of perceptiveness and sensitivity, Atul Gawande outlines a story that crosses the globe, as he examines his experiences as a surgeon and those of his patients and family, and learns to accept the limits of what he can do. Where Does it Hurt?: What the Junior Doctor did next He's into his second year of medicine, but this time Max is out of the wards and onto the streets, working for the Phoenix Outreach Project.Fuelled by tea and more enthusiasm than experience, he attempts to locate and treat a wide and colourful range of patients that somehow his first year on the wards didn't prepare him for . . . from Molly the 80-year-old drugs mule and God in a Tesco car park, to middle-class mums addicted to appearances and pain killers in equal measure.

    In The Last Diet., she shares how the same evidence-based tools she used effectively with her clients who struggle with addiction helped her to lose over a hundred pounds, increase her self-esteem, and transform her habits around food and negative self-talk. Diets often offer quick, short-term fixes and so-called miracle cures, but the real challenge is managing weight and changing habits over a sustained period of time. Everybody's journeys and needs are different: it’s about shifting the way we communicate with ourselves and our bodies every single day, in every aspect of our lives. Shahroo’s revolutionary kindness method gives readers the tools to embrace self-kindness and self-respect and in doing so change the narrative of health. Using a custom-tailored plan, The Last Diet. will help you identify where your unhealthy habits come from, teach you how change them, and show you what to do when you slip up. Shahroo guides you through every step, helping you to draw out your own wisdom and find motivation to change your long-term habits and lose weight – for good.

    We hurt ourselves, we feel pain, we seek help from a professional or learn to avoid certain behaviors that cause pain. But the story of what goes on in our body is far from simple. Even medical practitioners themselves often fail to grasp the complexities between our minds and bodies and how they interact when dealing with pain stimulus. Throughout history we’ve tried to prevent and mediate the effects of pain—which has only resulted in a highly medicated population and a booming opiates industry. Written by a medical expert trained as an anesthesiologist, An Anatomy of Pain is the first book to clearly explain the current issues and complexities surrounding the treatment of pain and how society deals with those in pain, as well as how our bodies relate to pain. Common conception still equates pain with tissue damage but that is only a very small part of the story—the organ which produces pain is the brain. Case studies show that a woman who has undergone a c-section reports dramatically less pain than a patient who has had kidney stones removed in a similarly invasive operation. The soldier who drags himself or herself to safety after being shot deals with pain in a remarkably different way from someone suffering a similar injury on a street. The truth is that pain is a complex mix of nerve endings, psychological state, social preconceptions, and situational awareness. Filled with case studies and medical history, this enlightening book offers a crash course in all aspects of pain, from chronic to acute, and walks us through the current landscape of pain treatments—from medication (including opioids) to electrical nerve stimulation. Whether it’s a mild ache or severe discomfort, we all encounter pain in our lives and “this splendid book—informative, empathic, and wise—about a universal experience will surely promote healing” (Booklist, starred review).

    You will learn how in this timely, urgent, and compassionate work by a world-renowned critical care doctor.Over the next ten years, 40 to 60 million people in this country will be admitted to the ICU. Most of these hospitalizations will be sudden, unexpected, and harrowing experiences that can alter patients and their families physically and emotionally, with effects that endure for years. In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent patients from being inadvertently harmed by the technology that is keeping them alive. You will experience the world of critical care through the eyes of a physician who drastically changed his clinical practice to offer person-centered health care, and through cutting-edge research convinced others to do the same. For decades, ICU survivors left the hospital with disabling symptoms including newly acquired dementia, depression, PTSD, and nerve damage, all now recognized as Post Intensive Care Syndrome, or PICS. Dr. Ely’s groundbreaking investigations advanced the understanding of PICS and introduced crucial changes that reshaped intensive care: minimizing sedation, maximizing mobility, listening to the family, and providing supportive aftercare. Dr. Ely shows that there are ways to bring humanity into the ICU and that “technology plus touch” is the future of health care and is a proven path toward returning ICU patients to the lives they had before their hospital stay. An essential resource for anyone who will be affected by illness—which is all of us—Ely’s “personal, passionate return to the ethical heart of the Hippocratic oath…[offers] meaningful, thought-provoking insight into the world of critical care” (Kirkus Reviews).

    Its organization and thoroughness are unsurpassed, putting it above similar review books. Students who thoroughly read this book should have no trouble successfully completing their psychiatry clerkship and passing the shelf exam. As course director for the core psychiatry clerkship at my institution, I will recommend this book to students."--Doody's Review Service"First Aid for the Psychiatry Clerkship" gives you the core information needed to impress on the wards and pass the psychiatry clerkship exam. Written by students who know what it takes to succeed, and based on the national guidelines for the psychiatry clerkship, the book is filled with mnemonics, ward and exam tips, tables, clinical images, algorithms, and newly added mini-cases.Features Completely revised based on the psychiatry clerkship's core competencies Written by medical students who passed and reviewed by faculty for accuracy NEW integrated mini-cases illustrate classic patient presentations and/or commonly tested scenarios NEW illustrations and management algorithms Updated throughout with enhanced sections on medications, depression/anxiety, and child psychiatry Helps students hone in on the most important concepts for the clerkship and the examThe content you need to ace the clerkship: Section I: How to Succeed in the Psychiatry Clerkship Section II: High-Yield Facts; Examination and Diagnosis; Psychotic Disorders; Mood Disorders; Anxiety and Adjustment Disorders; Personality Disorders; Substance-Related Disorders; Cognitive Disorders; Geriatric Disorders; Psychiatric Disorders in Children; Dissociative Disorders; Somataform and Factitious Disorders; Impulse Control Disorders; Eating Disordes; Disorders; Sleep Disorders; Sexual Disorders; Psychtherapies; Psychopharmacology; Legal Issues; Section III: Awards and Opportunities.

    Dilan Ellegala's quest to teach brain surgery in one of the poorest and most remote places on earth. In vivid detail, the book also exposes one of the world's most neglected but serious public health problems - one that kills more people than malaria, tuberculosis and AIDS combined.

    But what happens when doctors fall apart?Funny, fresh, and deeply affecting, We Are All Perfectly Fine is the story of a married mother of three on the brink of personal and professional collapse who attends rehab with a twist: a meditation retreat for burned-out doctors.Jillian Horton, a general internist, has no idea what to expect during her five-day retreat at Chapin Mill, a Zen centre in upstate New York. She just knows she desperately needs a break. At first she is deeply uncomfortable with the spartan accommodations, silent meals and scheduled bonding sessions. But as the group struggles through awkward first encounters and guided meditations, something remarkable happens: world-class surgeons, psychiatrists, pediatricians and general practitioners open up and share stories about their secret guilt and grief, as well as their deep-seated fear of falling short of the expectations that define them. Jillian realizes that her struggle with burnout is not so much personal as it is the result of a larger system failure, and that compartmentalizing your most difficult emotions—a coping strategy that is drilled into doctors—is not useful unless you face these emotions too.Jillian Horton throws open a window onto the flawed system that shapes medical professionals, revealing the rarely acknowledged stresses that lead doctors to depression and suicide, and emphasizing the crucial role of compassion not only in treating others, but also in taking care of ourselves.

    Kenneth Rosenberg trained as a psychiatrist in the late 1980s, the state mental hospitals, which had reached peak occupancy in the '50s, were being closed at an alarming rate, with many patients having nowhere to go. There has never been a more important time for this conversation, as one in five adults — 40 million Americans — experiences mental illness each year. Today, the largest mental institution in the U.S. is the LA County Jail, and the last refuge for many of the 20,000 mentally ill people living on the streets of Los Angeles is LA County Hospital. There, Dr. Rosenberg begins his chronicle of what it means to be mentally ill in America today, integrating his own moving story of how the system failed his sister, Merle, who had schizophrenia. As he says, "I have to come to see that my family's tragedy is an American tragedy. My family's shame is America's great secret."

    In this captivating fusion of science, history and personal memoir, writer David Adam explores the weird thoughts that exist within every mind, and how they drive millions of us towards obsessions and compulsions.David has suffered from OCD for twenty years, and The Man Who Couldn’t Stop is his unflinchingly honest attempt to understand the condition and his experiences. What might lead an Ethiopian schoolgirl to eat a wall of her house, piece by piece; or a pair of brothers to die beneath an avalanche of household junk that they had compulsively hoarded? At what point does a harmless idea, a snowflake in a clear summer sky, become a blinding blizzard of unwanted thoughts? Drawing on the latest research on the brain, as well as historical accounts of patients and their treatments, this is a book that will challenge the way you think about what is normal, and what is mental illness.Told with fierce clarity, humour and urgent lyricism, this extraordinary book is both the haunting story of a personal nightmare, and a fascinating doorway into the darkest corners of our minds.