With the assistance of a co-author, this popular student textbook has now been updated to include techniques such as membrane chromatography, aqueous phase partitioning, engineering recombinant proteins for purification and due to the rapid advances in bioinformatics/proteomics a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy. Written with the student firmly in mind, no previous knowledge of biochemistry, and little of chemistry, is assumed. It is intended to provide an introduction to enzymology, and a balanced account of all the various theoretical and applied aspects of the subject which are likely to be included in a course.

    One morning he misses his bus when he stops to put a strange caterpillar in a matchbox. As the bus passes he’s shocked to spot himself inside. Like Schrödinger’s Cat in the famous quantum thought experiment, the caterpillar's spawned parallel possibilities. This comic novel explores Graham’s search for a better life among the various overlapping alternatives.Another clone, Grim Dupeint, is a loathsome international arms dealer. Graham infiltrates Grim’s corporation, then embezzles cash for charity. When a furious Grim realises, Graham must act fast. And right now he's acting like fish food.Graham launches upon a new lifestyle (and sex life) as he dons the designer suits of power. But sinister figures soon see through Graham’s clothing. Now Graham’s under attack from the corporation, the police, his ex-wife’s private detective, and an infuriatingly pompous water-colourist who Graham might have been if he’d gone to art college rather than business school. To survive (and steal the artist’s wonderful woman) Graham needs to find hidden resources. By definition Dopplegraham’s equally resourceful. Bugger...Schrödinger's Caterpillar - a stupid book for brainy people!

    It expands on the foundation acquired in chemistry courses and enables students to understand the mechanisms as they come across them in your classroom or laboratory.Organic Reaction Mechanisms provides extensive coverage of various organic reaction and rearrangements with emphasis on their applications in syntheses. The authors discuss reaction pathways, such as substitutions, additions, eliminations, oxidations, reductions, aromatic substitutions, aliphatic nucleophilic substitution, and electrophilic substitutions with numerous reaction equations to show the mechanism. The text also details the various reaction intermediates, including carbocations, carbanions, free radicals, carbenes, nitrines, benzynes, arynes, ylides, and enamines.Furthermore, the reagents are surveyed throughout the text, and correlation tables are provided to aid in identifying which oxidation/reduction agents to use for oxidizing/reducing various types of compounds. The applications of organic reagents are illustrated with examples and problems at the end of each chapter, which also serve to review the mechanisms learned and topics discussed. A comprehensive discussion on organic reactions, Organic Reaction Mechanisms will benefit advanced undergraduate and graduate chemistry students in their understanding and application of organic syntheses.

    But ask what it means, and the result will be a brawl. For a century, most physicists have followed Niels Bohr's Copenhagen interpretation and dismissed questions about the reality underlying quantum physics as meaningless. A mishmash of solipsism and poor reasoning, Copenhagen endured, as Bohr's students vigorously protected his legacy, and the physics community favored practical experiments over philosophical arguments. As a result, questioning the status quo long meant professional ruin. And yet, from the 1920s to today, physicists like John Bell, David Bohm, and Hugh Everett persisted in seeking the true meaning of quantum mechanics. What Is Real? is the gripping story of this battle of ideas and of the courageous scientists who dared to stand up for truth.

     From the Number 1 Best Selling authors in Computers and Technology, this clear and concise guide will show you how to get the very best from your new Amazon Fire TV Streaming Stick Media Player. Step by step instructions will take you from newbie to expert in just one hour! About the Authors: Tom and Jenna Edwards are the Amazon Tech authors behind the Number 1 Best-selling e-books 250+ Best Kindle Fire HD Apps for the New Kindle Fire Owner and Kindle Fire HDX User Guide: Newbie to Expert in 2 Hours!

    . . lifts the curtain to reveal the inner workings of international cricket. A must-read for any cricketer, coach or fan' Eoin Morgan'This path-breaking book should be compulsory reading for commentators and captains - and all cricket fans' Mervyn King'Clever and original but also wise' Ed SmithHow valuable is winning the toss? And how should captains use it to their advantage? Why does a cricket ball swing? Why don't Indians bat left-handed? What is a good length and why? Why are leg-spinners so successful in T20 cricket? Why did England win the World Cup? Why do all Test bowlers bowl at either 55 or 85mph? Why don't they pitch it up?All cricketers long to know the answer to these questions and many more. Only fifteen years ago it would have been difficult to answer them - cricket was guided only by decades-old tradition and received wisdom. Data has changed everything. Today we can track every ball to within millimetres; its release point, speed and bounce point are measured as are how much the ball swings, how much it deviates off the pitch, the exact height and line that it passes the stumps, and multiple other variables. Hitting Against the Spin is the story of that data, and what it can tell us about how cricket really works. Leading cricket thinkers Nathan Leamon and Ben Jones lift the lid on international cricket and explain its hidden workings and dynamics - the forces that shape cricket and, in turn, the cricketers who play it. They analyse the unseen hands that determine which players succeed and which fail, which tactics work and which don't, which teams win and which lose. They also explore the new world of franchise cricket as well as the rapid evolution of the T20 format. Revolutionary in its insights, Hitting Against the Spin takes you on a fascinating whistle-stop tour of modern cricket and sports analytics, bringing cricket firmly into the twenty-first century by revealing its long-kept secrets. This is the most important cricket book in decades.

    Just about everyone has at least heard of Albert Einstein's formulation of 1905, which came into the world as something of an afterthought. But far fewer can explain his insightful linkage of energy to mass. David Bodanis offers an easily grasped gloss on the equation. Mass, he writes, "is simply the ultimate type of condensed or concentrated energy," whereas energy "is what billows out as an alternate form of mass under the right circumstances." Just what those circumstances are occupies much of Bodanis's book, which pays homage to Einstein and, just as important, to predecessors such as Maxwell, Faraday, and Lavoisier, who are not as well known as Einstein today. Balancing writerly energy and scholarly weight, Bodanis offers a primer in modern physics and cosmology, explaining that the universe today is an expression of mass that will, in some vastly distant future, one day slide back to the energy side of the equation, replacing the "dominion of matter" with "a great stillness"--a vision that is at once lovely and profoundly frightening. Without sliding into easy psychobiography, Bodanis explores other circumstances as well; namely, Einstein's background and character, which combined with a sterling intelligence to afford him an idiosyncratic view of the way things work--a view that would change the world. --Gregory McNamee

    This set couples a book containing the six easiest chapters from Richard P. Feynman's landmark work, Lectures on Physics—specifically designed for the general, non-scientist reader—with the actual recordings of the late, great physicist delivering the lectures on which the chapters are based. Nobel Laureate Feynman gave these lectures just once, to a group of Caltech undergraduates in 1961 and 1962, and these newly released recordings allow you to experience one of the Twentieth Century's greatest minds—as if you were right there in the classroom.

    For almost 500 years, the masses have been thoroughly deceived by a cosmic fairy-tale of astronomical proportions. We have been taught a falsehood so gigantic and diabolical that it has blinded us from our own experience and common sense, from seeing the world and the universe as they truly are. Through pseudo-science books and programs, mass media and public education, universities and government propaganda, the world has been systematically brain-washed, slowly indoctrinated over centuries into the unquestioning belief of the greatest lie of all time. A multi-generational conspiracy has succeeded, in the minds of the masses, to pick up the fixed Earth, shape it into a ball, spin it in circles, and throw it around the Sun! The greatest cover-up of all time, NASA and Freemasonry's biggest secret, is that we are living on a plane, not a planet, that Earth is the flat, stationary center of the universe.

    This fascinating book showcases hundreds of eye-catching tattoos that pay tribute to various scientific disciplines, from evolutionary biology and neuroscience to mathematics and astrophysics, and reveals the stories of the individuals who chose to inscribe their obsessions in their skin. Best of all, each tattoo provides a leaping-off point for bestselling essayist and lecturer Zimmer to reflect on the science in question, whether it's the importance of an image of Darwin's finches or the significance of the uranium atom inked into the chest of a young radiologist.

    But ask a physicist and there’s no doubt that James Clerk Maxwell will be near the top of the list.  Maxwell, an unassuming Victorian Scotsman, explained how we perceive colour. He uncovered the way gases behave. And, most significantly, he transformed the way physics was undertaken in his explanation of the interaction of electricity and magnetism, revealing the nature of light and laying the groundwork for everything from Einstein’s special relativity to modern electronics.   Along the way, he set up one of the most enduring challenges in physics, one that has taxed the best minds ever since. ‘Maxwell’s demon’ is a tiny but thoroughly disruptive thought experiment that suggests the second law of thermodynamics, the law that governs the flow of time itself, can be broken. This is the story of a groundbreaking scientist, a great contributor to our understanding of the way the world works, and his duplicitous demon.

    

    Brian Greene, one of the world's leading string theorists, peels away the layers of mystery surrounding string theory to reveal a universe that consists of eleven dimensions, where the fabric of space tears and repairs itself, and all matter—from the smallest quarks to the most gargantuan supernovas—is generated by the vibrations of microscopically tiny loops of energy.Today physicists and mathematicians throughout the world are feverishly working on one of the most ambitious theories ever proposed: superstring theory. String theory, as it is often called, is the key to the Unified Field Theory that eluded Einstein for more than thirty years. Finally, the century-old antagonism between the large and the small-General Relativity and Quantum Theory-is resolved. String theory proclaims that all of the wondrous happenings in the universe, from the frantic dancing of subatomic quarks to the majestic swirling of heavenly galaxies, are reflections of one grand physical principle and manifestations of one single entity: microscopically tiny vibrating loops of energy, a billionth of a billionth the size of an atom. In this brilliantly articulated and refreshingly clear book, Greene relates the scientific story and the human struggle behind twentieth-century physics' search for a theory of everything.Through the masterful use of metaphor and analogy, The Elegant Universe makes some of the most sophisticated concepts ever contemplated viscerally accessible and thoroughly entertaining, bringing us closer than ever to understanding how the universe works.

    Now an internationally recognized scientist at a top U.S. medical school—one of the leading researchers in the field—sheds light on the extraordinary benefits of these natural health superstars. Thanks to an explosion of research in recent years, one thing is clear: probiotics, the healthy bacteria that inhabit the digestive tract, are the body’s silent partners for good health, optimizing the power of the immune system to fight disease and the “bad” germs we fear. But how do they work? And in the face of factors like stress and poor diet, which decrease their numbers, how do you keep your supply well stocked? Here is an up-to-the-minute, highly accessible guide to probiotics and the foods and supplements that contain and support them—many of which may be in your diet already. Discover:The key role of probiotics and prebiotics in restoring healthy balance to our bodies, improving immune system functioning, and curbing inflammationHow to use probiotic foods and supplements to prevent and relieve allergies, inflammatory bowel disease, irritable bowel syndrome, yeast infections, and the negative side effects of antibiotic useNew evidence that probiotics may help fight asthma, cardiovascular disease, breast and colon cancer, autoimmune diseases, chronic fatigue, fibromyalgia—and even obesityNatural sources of prebiotics, the nutrients that help make the digestive tract more hospitable for probiotic bacteriaThe Probiotics Revolution also includes a step-by-step plan for incorporating the many food sources of probiotics and prebiotics into your diet, a complete buyer’s guide to probiotic supplements, and how to introduce probiotics to your family and children.From the Hardcover edition.

    Now he makes the case that living on Mars is not just plausible, but inevitable.It sounds like science fiction, but Stephen Petranek considers it fact: Within twenty years, humans will live on Mars. We'll need to. In this sweeping, provocative book that mixes business, science, and human reporting, Petranek makes the case that living on Mars is an essential back-up plan for humanity and explains in fascinating detail just how it will happen.The race is on. Private companies, driven by iconoclastic entrepreneurs, such as Elon Musk, Jeff Bezos, Paul Allen, and Sir Richard Branson; Dutch reality show and space mission Mars One; NASA; and the Chinese government are among the many groups competing to plant the first stake on Mars and open the door for human habitation. Why go to Mars? Life on Mars has potential life-saving possibilities for everyone on earth. Depleting water supplies, overwhelming climate change, and a host of other disasters — from terrorist attacks to meteor strikes — all loom large. We must become a space-faring species to survive. We have the technology not only to get humans to Mars, but to convert Mars into another habitable planet. It will likely take 300 years to "terraform" Mars, as the jargon goes, but we can turn it into a veritable second Garden of Eden. And we can live there, in specially designed habitations, within the next twenty years.In this exciting chronicle, Petranek introduces the circus of lively characters all engaged in a dramatic effort to be the first to settle the Red Planet. How We'll Live on Mars brings firsthand reporting, interviews with key participants, and extensive research to bear on the question of how we can expect to see life on Mars within the next twenty years.