For more than two centuries, our understanding of the laws of nature expanded rapidly. But today, despite our best efforts, we know nothing more about these laws than we knew in the 1970s. Why is physics suddenly in trouble? And what can we do about it?One of the major problems, according to Smolin, is string theory: an ambitious attempt to formulate a “theory of everything” that explains all the particles and forces of nature and how the universe came to be. With its exotic new particles and parallel universes, string theory has captured the public’s imagination and seduced many physicists.But as Smolin reveals, there’s a deep flaw in the theory: no part of it has been tested, and no one knows how to test it. In fact, the theory appears to come in an infinite number of versions, meaning that no experiment will ever be able to prove it false. As a scientific theory, it fails. And because it has soaked up the lion’s share of funding, attracted some of the best minds, and effectively penalized young physicists for pursuing other avenues, it is dragging the rest of physics down with it.With clarity, passion, and authority, Smolin charts the rise and fall of string theory and takes a fascinating look at what will replace it. A group of young theorists has begun to develop exciting ideas that, unlike string theory, are testable. Smolin not only tells us who and what to watch for in the coming years, he offers novel solutions for seeking out and nurturing the best new talent—giving us a chance, at long last, of finding the next Einstein.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

    Written by Curie’s daughter, the renowned international activist Eve Curie, this biography chronicles Curie’s legendary achievements in science, including her pioneering efforts in the study of radioactivity and her two Nobel Prizes in Physics and Chemistry. It also spotlights her remarkable life, from her childhood in Poland, to her storybook Parisian marriage to fellow scientist Pierre Curie, to her tragic death from the very radium that brought her fame. Now updated with an eloquent, rousing introduction by best-selling author Natalie Angier, this timeless biography celebrates an astonishing mind and a extraordinary woman’s life.

    Birth of a Theorem is Villani’s own account of the years leading up to the award. It invites readers inside the mind of a great mathematician as he wrestles with the most important work of his career.But you don’t have to understand nonlinear Landau damping to love Birth of a Theorem. It doesn’t simplify or overexplain; rather, it invites readers into collaboration. Villani’s diaries, emails, and musings enmesh you in the process of discovery. You join him in unproductive lulls and late-night breakthroughs. You’re privy to the dining-hall conversations at the world’s greatest research institutions. Villani shares his favorite songs, his love of manga, and the imaginative stories he tells his children. In mathematics, as in any creative work, it is the thinker’s whole life that propels discovery—and with Birth of a Theorem, Cédric Villani welcomes you into his.

    How can it be possible that the world we see is not objective reality? And how can our senses be useful if they are not communicating the truth? Hoffman grapples with these questions and more over the course of this eye-opening work.Ever since Homo sapiens has walked the earth, natural selection has favored perception that hides the truth and guides us toward useful action, shaping our senses to keep us alive and reproducing. We observe a speeding car and do not walk in front of it; we see mold growing on bread and do not eat it. These impressions, though, are not objective reality. Just like a file icon on a desktop screen is a useful symbol rather than a genuine representation of what a computer file looks like, the objects we see every day are merely icons, allowing us to navigate the world safely and with ease.The real-world implications for this discovery are huge. From examining why fashion designers create clothes that give the illusion of a more “attractive” body shape to studying how companies use color to elicit specific emotions in consumers, and even dismantling the very notion that spacetime is objective reality, The Case Against Reality dares us to question everything we thought we knew about the world we see.

    It would be wonderful if they came to us unsummoned, but particularly in lives as busy as the ones most of us lead now, that won’t happen. We have to teach ourselves now to live, really live . . . to love the journey, not the destination.” In this treasure of a book, Anna Quindlen, the bestselling novelist and columnist, reflects on what it takes to “get a life”—to live deeply every day and from your own unique self, rather than merely to exist through your days. “Knowledge of our own mortality is the greatest gift God ever gives us,” Quindlen writes, “because unless you know the clock is ticking, it is so easy to waste our days, our lives.” Her mother died when Quindlen was nineteen: “It was the dividing line between seeing the world in black and white, and in Technicolor. The lights came on for the darkest possible reason. . . . I learned something enduring, in a very short period of time, about life. And that was that it was glorious, and that you had no business taking it for granted.” But how to live from that perspective, to fully engage in our days? In A Short Guide to a Happy Life, Quindlen guides us with an understanding that comes from knowing how to see the view, the richness in living.

    In so doing, he reaches a provocative conclusion: science, the main tool we use to find answers, is fundamentally limited.These limits to our knowledge arise both from our tools of exploration and from the nature of physical reality: the speed of light, the uncertainty principle, the impossibility of seeing beyond the cosmic horizon, the incompleteness theorem, and our own limitations as an intelligent species. Recognizing limits in this way, Gleiser argues, is not a deterrent to progress or a surrendering to religion. Rather, it frees us to question the meaning and nature of the universe while affirming the central role of life and ourselves in it. Science can and must go on, but recognizing its limits reveals its true mission: to know the universe is to know ourselves.Telling the dramatic story of our quest for understanding, The Island of Knowledge offers a highly original exploration of the ideas of some of the greatest thinkers in history, from Plato to Einstein, and how they affect us today. An authoritative, broad-ranging intellectual history of our search for knowledge and meaning, The Island of Knowledge is a unique view of what it means to be human in a universe filled with mystery.

    But evolutionary biologists also point out many examples of contingency, cases where the tiniest change--a random mutation or an ancient butterfly sneeze--caused evolution to take a completely different course. What role does each force really play in the constantly changing natural world? Are the plants and animals that exist today, and we humans ourselves, inevitabilities or evolutionary freaks? And what does that say about life on other planets?Jonathan Losos reveals what the latest breakthroughs in evolutionary biology can tell us about one of the greatest ongoing debates in science. He takes us around the globe to meet the researchers who are solving the deepest mysteries of life on Earth through their work in experimental evolutionary science. Losos himself is one of the leaders in this exciting new field, and he illustrates how experiments with guppies, fruit flies, bacteria, foxes, and field mice, along with his own work with anole lizards on Caribbean islands, are rewinding the tape of life to reveal just how rapid and predictable evolution can be.Improbable Destinies will change the way we think and talk about evolution. Losos's insights into natural selection and evolutionary change have far-reaching applications for protecting ecosystems, securing our food supply, and fighting off harmful viruses and bacteria. This compelling narrative offers a new understanding of ourselves and our role in the natural world and the cosmos.

    Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

     Psychologists have long been aware that most people maintain an often irrationally positive outlook on life. In fact, optimism may be crucial to our existence. Tali Sharot’s experiments, research, and findings in cognitive science have contributed to an increased understanding of the biological basis of optimism. In this fascinating exploration, she takes an in-depth, clarifying look at how the brain generates hope and what happens when it fails; how the brains of optimists and pessimists differ; why we are terrible at predicting what will make us happy; how emotions strengthen our ability to recollect; how anticipation and dread affect us; and how our optimistic illusions affect our financial, professional, and emotional decisions.  With its cutting-edge science and its wide-ranging and accessible narrative, The Optimism Bias provides us with startling new insight into the workings of the brain.From the Hardcover edition.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.

    Lehninger Principles of Biochemistry, Fourth Edition brings clarity and coherence to an often unwieldy discipline, while incorporating the field's most important recent developments and applications.

    Featuring two of Chomsky's most popular and enduring books in one omnibus volume, On Language contains some of the noted linguist and political critic's most informal and accessible work to date, making it an ideal introduction to his thought.In Part I, Language and Responsibility (1979), Chomsky presents a fascinating self-portrait of his political, moral, and linguistic thinking through a series of interviews with Mitsou Ronat, the noted French linguist. In Part II, Reflections on Language (1975), Chomsky explores the more general implications of the study of language and offers incisive analyses of the controversies among psychologists, philosophers, and linguists over fundamental questions of language.

    He traced the ownership of individual copies through the hands of saints, heretics, scalawags, and bibliomaniacs. He was called as the expert witness in the theft of one copy, witnessed the dramatic auction of another, and proves conclusively that "De revolutionibus" was as inspirational as it was revolutionary. Part biography of a book, part scientific exploration, part bibliographic detective story, "The Book Nobody Read" recolors the history of cosmology and offers new appreciation of the enduring power of an extraordinary book and its ideas.