The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    This latest book gives you a precise regimen for self-treatment along with extensive information on other resources now available to you.

    If you have ever wanted to read a book that validates immortality and communication with loved ones who have passed on, then read this book. It is an authentic portal to the other side." Caroline Myss, author of Anatomy of the SpiritWhen Mike and Beth Pasakarnis received the news that every parent dreads, their world seemed to crumble around them. Spiritual teacher and evidential medium Suzanne Giesemann knew exactly how they felt. Like Mike and Beth’s son, Wolf, her step-daughter Susan had been struck and killed by a bolt of lightning out of the blue. Until meeting Mike and Beth, Suzanne—a former “by-the-book” Navy commander—had cautiously refrained from using the word “proof” when speaking of the eternal existence of the soul. But no longer. The evidence Mike and Beth shared from their son provided all the proof she needed. Little did Mike, Beth, or Suzanne know that their lives would soon become even more entangled by unexpected visits from Wolf’s spirit. Had Wolf’s presence offered a one-time glimpse across the veil, they might still be pondering the significance of the mystifying clues he left behind. Instead, as Wolf repeatedly made his presence known, Suzanne was able to piece together Wolf’s puzzle and reveal a startling message that has profound spiritual implications for us all. Travel along on Suzanne’s incredible journey as she unravels the web of clues Wolf wove to ensure that his uplifting message of hope and joy is understood by all mankind. "Part spiritual detective story, part definitive proof of after-death communications from a most extraordinary young man, Wolf’s Message is above all a must-read for those seeking a more balanced, heart-centered way of living." Kenneth Ring, Ph.D., author of Lessons from the Light“Wolf’s efforts to communicate with us through Suzanne deserve to be taken seriously and received with gratitude, awe, and celebration.” Gary E. Schwartz, Ph.D., author of The Sacred Promise “Somehow, reading Wolf's Message creates a field into which the reader is incorporated experientially. Reading, learning, and Being are rolled into a synergy that exemplifies the truths of nature and existence as they are revealed. Such authentic interactivity is rarely achieved in this context; a really good book is one in which the author draws the reader in by chronicling notions and events in such a way as to invite and affirm our ability to relate. A really great story dispenses with the dichotomy of author and reader altogether, and the precious anomaly of Wolf's Message is that it behaves more like an Oracle than a Book.” Dr. Barbara E. Fields, Executive Director, Association for Global New Thought

    The volume also includes two contemporary and conflicting reviews by Roger Hughes and Pauline Kael, a detailed glossary of nadsat and reproductions of stills from the film.

    A full pharmacopoeia of natural remedies for common ailments and injuries, it also contains sections on homeopathy for children and pets.It covers the history and use of homeopathy in the home. It covers a wide variety of aspects of illness and homeopathy and chapters cover the following:What is Homeopathy?A Homeopathic Physician at WorkYour Home Remedy KitWhat to Do for AccidentsIn Case of EmergencyHow to Prevent and Treat Colds, Coughs and EarachesRemedies for Stomach and Bowel ProblemsA Happier Baby with Homeopathic CareYour Growing ChildWhat Homeopathy Can Do for WomenKeeping Your Pets HealthyRemedies and their AbbreviationsMini-RepertoryMateria Medica

    *Includes Cagney's own quotes about his life and career. *Includes a bibliography for further reading. *Includes a table of contents. "You don't psych yourself up for these things, you do them...I'm acting for the audience, not for myself, and I do it as directly as I can." – James Cagney A lot of ink has been spilled covering the lives of history’s most influential figures, but how much of the forest is lost for the trees? In Charles River Editors’ American Legends series, readers can get caught up to speed on the lives of America’s most important men and women in the time it takes to finish a commute, while learning interesting facts long forgotten or never known. When the American Film Institute assembled its top 100 actors of all time at the close of the 20th century, one of the Top 10 was James Cagney, an actor whose acting and dancing talents spawned a stage and film career that spanned over 5 decades and once compelled Orson Welles to call him "maybe the greatest actor to ever appear in front of a camera." Indeed, his portrayal of “The Man Who Owns Broadway”, George M. Cohan, earned him an Academy Award in the musical Yankee Doodle Dandy, and as famed director Milos Forman once put it, "I think he's some kind of genius. His instinct, it's just unbelievable. I could just stay at home. One of the qualities of a brilliant actor is that things look better on the screen than the set. Jimmy has that quality." Ultimately, it was portraying tough guys and gangsters in the 1930s that turned Cagney into a massive Hollywood star, and they were the kind of roles he was literally born to play after growing up rough in Manhattan at the turn of the 20th century. In movies like The Public Enemy (which included the infamous “grapefruit scene”) and White Heat, Cagney convincingly played criminals that brought Warner to the forefront of Hollywood and the gangster genre. Cagney also helped pave the way for younger actors in the genre, like Humphrey Bogart, and he was so good that he found himself in danger of being typecast. While Cagney is no longer remembered as fondly or as well as Bogart, he was also crucial in helping establish the system in which actors worked as independent workers free from the constraints of studios. Refusing to be pushed around, Cagney was constantly involved in contract squabbles with Warner, and he often came out on top, bucking the conventional system that saw studios treat their stars as indentured servants who had to make several films a year. American Legends: The Life of James Cagney examines the life and career of one of Hollywood’s most iconic actors. Along with pictures of important people, places, and events, you will learn about Cagney like never before, in no time at all.

    Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.Features: NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body. New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text Medical applications explain the clinical relevance of each topic Complete coverage of every tissue of the body CD-ROM with all the images from the textVisit www.LangeTextbooks.com to access valuable resources and study aids

    Unlike many Hollywood stars who do their best to avoid the press, her openness about her complicated and often outlandish life has endeared her to fans worldwide. Her most famous screen roles are covered in this biography, from Gia to Lara Croft, which established her as one of the highest paid actresses in Hollywood. Also explored is her reputation for living on the edge, and Angelina's refreshing honesty around tempestuous romantic relationships, bisexuality, wild partying, and breakdowns and thoughts of suicide. Finally, her recent roles as philanthropist, mother, and half of a Hollywood golden couple with Brad Pitt, are also discussed in this inspiring must-read book for fans of this continually fascinating global superstar.

    Edward Marriott’s dramatic, gripping new book gives you yet another thing to worry about.” —New York Plague. The very word carries an unholy resonance. No other disease can claim its apocalyptic power: it can lie dormant for centuries, only to resurface with nation-killing force. Here, with the high drama of an adventure tale, Edward Marriott unravels the story of this lethal disease: the historic battle to identify its source, the devastating effects of pandemics, and the prospects for new outbreaks. Marriott begins the trail in Hong Kong in the summer of 1894, when a plague diagnosis brought to the island two top scientists—Alexandre Yersin, a maverick Frenchman, and his Japanese rival, Shibasaburo Kitasato. Marriott interweaves the narrative of their fierce competition with vivid scenes of the scourge’s persistence: California in 1900; Surat, India, in 1994; and New York City sometime in the future.A masterly account of medical and human history, Plague is at once an instructive warning and a chilling read.

    What does that mean?" "Will I ever be able to have a baby?" "I try to lose the weight, but I'm hungry all the time." "Why can't I just stop eating sugary, fattening foods?" "Why do I have hair growing everywhere and will it ever get better?" "I am so depressed and moody. Is this related to my PCOS?" If any of these statements sound familiar, this workbook can help you! The PCOS Workbook, a practical and comprehensive guide, helps you understand not just the physiology of PCOS, but what you can do about it. Step-by-step guidelines, questionnaires and exercises will help you learn skills and empower you to make positive changes in your life that might not get rid of PCOS, but will help you live with it harmoniously: Lose weight, take control over your eating and improve your health Understand your medical treatment Improve your fertility Manage the stress in your life Be mindful with your eating and in life Challenge body image myths and insecurities Overcome obstacles to becoming more physically active Cope with the challenges of infertility ...and get closer to living the life you want to live!

    What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound:• A figure skater whose body has become a ticking time-bomb • A salesman who drives around and around a traffic rotary, unable to get off • A college quarterback who can't stop calling the same play • A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive • A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth livingHow does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance.

    Jerry Avorn has some sobering news. Drawing on more than twenty-five years of patient care, teaching, and research at Harvard Medical School, he shares his firsthand experience of the wide gap in our knowledge of the effectiveness of one medication as compared to another. In Powerful Medicines, he reminds us that every pill we take represents a delicate compromise between the promise of healing, the risk of side effects, and an increasingly daunting price. The stakes on each front grow higher every year as new drugs with impressive power, worrisome side effects, and troubling costs are introduced.This is a comprehensive behind-the-scenes look at issues that affect everyone: our shortage of data comparing the worth of similar drugs for the same condition; alarming lapses in the detection of lethal side effects; the underuse of life-saving medications; lavish marketing campaigns that influence what doctors prescribe; and the resulting upward spiral of costs that places vital drugs beyond the reach of many Americans.In this engagingly written book, Dr. Avorn asks questions that will interest every consumer: How can a product judged safe by the Food and Drug Administration turn out to have unexpectedly lethal side effects? Why has the nation’s drug bill been growing at nearly 20 percent per year? How can physicians and patients pick the best medication in its class? How do doctors actually make their prescribing decisions, and why do those decisions sometimes go wrong? Why do so many Americans suffer preventable illnesses and deaths that proper drug use could have averted? How can the nation gain control over its escalating drug budget without resorting to rationing or draconian governmental controls?Using clinical case histories taken from his own work as a practitioner, researcher, and advocate, Dr. Avorn demonstrates the impressive power of the well-conceived prescription as well as the debacles that can result when medications are misused. He describes an innovative program that employs the pharmaceutical industry’s own marketing techniques to reduce use of some of the most overprescribed and overpriced products. Powerful Medicines offers timely and practical advice on how the nation can improve its drug-approval process, and how patients can work with doctors to make sure their prescriptions are safe, effective, and as affordable as possible. This is a passionate and provocative call for action as well as a compelling work of clear-headed science.From the Hardcover edition.

    Now she gives readers an up close look at her adventures in emergency medicine in her memoir, The Other Side of the Gurney.After twenty years working as an EMT and paramedic, Carson-Romano becomes a registered nurse specializing in critical care. She shares what it's like to be an "accidental hero" and offers these stories as a tribute to those invited into people's homes and lives during the most frightening times imaginable. Carson-Romano crafts her stories with compassion and humor while covering a wide range of experiences, including childbirths in dramatic situations, traumatic accidents, and patients nearing the ends of their lives.The sad, funny, and feel good times are all here—and will make readers appreciate the emergency medical responders who risk their own lives to save ours.

    He shares the stories of encounters that are, by turn, poignant, dramatic and funny.Using simple and illuminating language Tubridy also explains well-known conditions like multiple sclerosis, motor neuron disease and Parkinson's and and brings us into the examining room as he accompanies patients with these diagnoses on their challenging path.In addition, he reflects candidly on the reasons he, a doctor's son, went into medicine, how he has been tested, and what he has learned about people - and about himself - along the way.