Miller, is the most significant chemical substance mankind has ever encountered. So ancient that remains of poppies have been found in Neolithic tombs, it is the most effective drug ever discovered for treating pain. Whatever advances are made in medicine, Miller adds, nothing could really be more important than that. And yet, when it comes to mind-altering substances, morphine is only a cc or two in a vast river that flows through human civilization, ranging LSD to a morning cup of tea.In DRUGGED, Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture. The vast scope of chemicals that cross the blood-brain barrier boggle the very brain they reach: cannabis and cocaine, antipsychotics and antidepressants, alcohol, amphetamines, and Ecstasy-and much more. Literate and wide-ranging, Miller weaves together science and history, telling the story of the undercover theft of 20,000 tea plants from China by a British spy, for example, the European discovery of coffee and chocolate, and how James Wolfgang von Goethe, the famous man of letters, first isolated the alkaloid we now know as caffeine. Miller explains what scientists know-and don't-about the impact of each drug on the brain, down to the details of neurotransmitters and their receptors. He clarifies the differences between morphine and heroin, mescaline and LSD, and other similar substances. Drugged brims with surprises, revealing the fact that antidepressant drugs evolved from the rocket fuel that shot V2 rockets into London during World War II, highlighting the role of hallucinogens in the history of religion, and asking whether Prozac can help depressed cats.Entertaining and authoritative, Drugged is a truly fascinating book.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    From the mythical beasts of ancient Greece to the hormonal vampires of the Twilight saga, monsters have captivated us for millennia. Matt Kaplan, a noted science journalist and monster-myth enthusiast, employs an entertaining mix of cutting-edge research and a love of lore to explore the history behind these fantastical fictions and our hardwired obsession with things that go bump in the night. Ranging across history, Medusa’s Gaze and Vampire’s Bite tackles the enduring questions that arise on the frontier between fantasy and reality. What caused ancient Minoans to create the tale of the Minotaur and its subterranean maze? Did dragons really exist? What inspired the creation of vampires and werewolves, and why are we so drawn to them? With the eye of a journalist and the voice of a storyteller, Kaplan takes readers to the forefront of science, where our favorite figures of horror may find real-life validation. Does the legendary Kraken, a squid of epic proportions, really roam the deep? Are we close to making Jurassic Park a reality by replicating a dinosaur from fossilized DNA? As our fears evolve, so do our monsters, and Medusa’s Gaze and Vampire’s Bite charts the rise of the ultimate beasts, humans themselves.

    Its presence in nature was dismissed as a desperate response to starvation or other life-threatening circumstances, and few spent time studying it. A taboo subject in our culture, the behavior was portrayed mostly through horror movies or tabloids sensationalizing the crimes of real-life flesh-eaters. But the true nature of cannibalism--the role it plays in evolution as well as human history--is even more intriguing (and more normal) than the misconceptions we've come to accept as fact. In Cannibalism: A Perfectly Natural History, zoologist Bill Schutt sets the record straight, debunking common myths and investigating our new understanding of cannibalism's role in biology, anthropology, and history in the most fascinating account yet written on this complex topic. Schutt takes readers from Arizona's Chiricahua Mountains, where he wades through ponds full of tadpoles devouring their siblings, to the Sierra Nevadas, where he joins researchers who are shedding new light on what happened to the Donner Party--the most infamous episode of cannibalism in American history. He even meets with an expert on the preparation and consumption of human placenta (and, yes, it goes well with Chianti). Bringing together the latest cutting-edge science, Schutt answers questions such as why some amphibians consume their mother's skin; why certain insects bite the heads off their partners after sex; why, up until the end of the twentieth century, Europeans regularly ate human body parts as medical curatives; and how cannibalism might be linked to the extinction of the Neanderthals. He takes us into the future as well, investigating whether, as climate change causes famine, disease, and overcrowding, we may see more outbreaks of cannibalism in many more species--including our own.Cannibalism places a perfectly natural occurrence into a vital new context and invites us to explore why it both enthralls and repels us.

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    Almost a decade earlier, Dr. Sacks had published his masterpiece Awakenings but the book had hardly been an immediate success, and the rumpled clinician was still largely unknown. Over the ensuing four years, the two men worked closely together until Sacks asked Weschler to abandon the profile, a request to which Weschler acceded. The two remained close friends, however, across the next thirty years and then, just as Sacks was dying, he urged Weschler to take up the project once again. This book is the result of that entreaty.Weschler sets Sacks's brilliant table talk and extravagant personality in vivid relief. We see Sacks rowing and ranting and caring deeply; composing the essays that would form The Man Who Mistook His Wife for a Hat ; recalling his turbulent drug-fueled younger days; helping his patients and exhausting his friends; and waging intellectual war against a medical and scientific establishment that failed to address his greatest concern: the spontaneous specificity of the individual human soul. And all the while he is pouring out a stream of glorious, ribald, hilarious, and often profound conversation that establishes him as one of the great talkers of the age.

    The "Theory of Everything" that appears to be emerging includes everything but us: the feelings, meanings, consciousness, and purposes that make us (and many of our animal cousins) what we are. These most immediate and incontrovertible phenomena are left unexplained by the natural sciences because they lack the physical properties—such as mass, momentum, charge, and location—that are assumed to be necessary for something to have physical consequences in the world. This is an unacceptable omission. We need a "theory of everything" that does not leave it absurd that we exist.Incomplete Nature begins by accepting what other theories try to deny: that, although mental contents do indeed lack these material-energetic properties, they are still entirely products of physical processes and have an unprecedented kind of causal power that is unlike anything that physics and chemistry alone have so far explained. Paradoxically, it is the intrinsic incompleteness of these semiotic and teleological phenomena that is the source of their unique form of physical influence in the world. Incomplete Nature meticulously traces the emergence of this special causal capacity from simple thermodynamics to self-organizing dynamics to living and mental dynamics, and it demonstrates how specific absences (or constraints) play the critical causal role in the organization of physical processes that generate these properties.The book's radically challenging conclusion is that we are made of these specific absenses—such stuff as dreams are made on—and that what is not immediately present can be as physically potent as that which is. It offers a figure/background shift that shows how even meanings and values can be understood as legitimate components of the physical world.

    Weaving together history, science, and the latest theories of artificial intelligence, Lynch and Granger demystify the complexities of our brains, and show us how our memory, cognition, and intelligence actually function, as well as what mechanisms in the brain can potentially be enhanced, improving on the current design. Author of The Emotional Brain, Joseph LeDoux praised it as "provocative and fascinating," and, writing in the New Scientist, Willian Calvin called it "a popular account of how brains enlarge, in both evolutionary and developmental terms" and "a much needed book."

    How do trances, visions, prayer, satori, and other mystical experiences “work”? What induces and defines them? Is there a scientific explanation for religious mysteries and transcendent meditation?John Horgan investigates a wide range of fields — chemistry, neuroscience, psychology, anthropology, theology, and more — to narrow the gap between reason and mystical phenomena. As both a seeker and an award-winning journalist, Horgan consulted a wide range of experts, including theologian Huston Smith, spiritual heir to Joseph Campbell; Andrew Newberg, the scientist whose quest for the “God module” was the focus of a Newsweek cover story; Ken Wilber, prominent transpersonal psychologist; Alexander Shulgin, legendary psychedelic drug chemist; and Susan Blackmore, Oxford-educated psychologist, parapsychology debunker, and Zen practitioner.Horgan explores the striking similarities between “mystical technologies” like sensory deprivation, prayer, fasting, trance, dancing, meditation, and drug trips. He participates in experiments that seek the neurological underpinnings of mystical experiences. And, finally, he recounts his own search for enlightenment — adventurous, poignant, and sometimes surprisingly comic. Horgan’s conclusions resonate with the controversial climax of The End of Science, because, as he argues, the most enlightened mystics and the most enlightened scientists end up in the same place — confronting the imponderable depth of the universe.

    Known for its balanced coverage of the 3 perspectives, this text continues to encourage students to think about their world with a sociological imagination. Through its strong coverage of globalization, race and ethnicity, careers in sociology, and current topics like mass media and social policy, Sociology provides students with knowledge they can use on campus, at work, in their neighborhoods, and in the global community. The new 12th edition features updated sections in various chapters reflecting recent sociological changes like the impact of the current economic downturn on social class and the global culture war. New Research Today boxes provide students with relevant examples of sociological research.

    For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects while family members sit by, watching their loved ones disappear a little more each day until the person they used to know is gone forever. The disease was first described by German psychologist and neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer's, but it still affects millions around the world, and there is no cure in sight.In The End of Memory, award-winning science author Jay Ingram writes a biography of this disease that attacks the brains of patients. He charts the history of the disease from before it was noted by Alois Alzheimer through to the twenty-first century, explains the fascinating science of plaques and tangles, recounts the efforts to understand and combat the disease, and introduces us to the passionate researchers who are working to find a cure.An illuminating biography of "the plague of the twenty-first century" and scientists' efforts to understand and, they hope, prevent it, The End of Memory is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions.

    In this collection of personal and revealing essays, he explores the nature of his anthropological work in relation to a broader public, serving as the foremost spokesperson of his generation of scholars, those who came of age after World War II. His reflections are written in a style that both entertains and disconcerts, as they engage us in topics ranging from moral relativism to the relationship between cultural and psychological differences, from the diversity and tension among activist faiths to ethnic conflict in today's politics.Geertz, who once considered a career in philosophy, begins by explaining how he got swept into the revolutionary movement of symbolic anthropology. At that point, his work began to encompass not only the ethnography of groups in Southeast Asia and North Africa, but also the study of how meaning is made in all cultures--or, to use his phrase, to explore the frames of meaning in which people everywhere live out their lives. His philosophical orientation helped him to establish the role of anthropology within broader intellectual circles and led him to address the work of such leading thinkers as Charles Taylor, Thomas Kuhn, William James, and Jerome Bruner. In this volume, Geertz comments on their work as he explores questions in political philosophy, psychology, and religion that have intrigued him throughout his career but that now hold particular relevance in light of postmodernist thinking and multiculturalism. Available Light offers insightful discussions of concepts such as nation, identity, country, and self, with a reminder that like symbols in general, their meanings are not categorically fixed but grow and change through time and place.This book treats the reader to an analysis of the American intellectual climate by someone who did much to shape it. One can read Available Light both for its revelation of public culture in its dynamic, evolving forms and for the story it tells about the remarkable adventures of an innovator during the golden years of American academia.

    Have you ever wondered if your dog might be a bit depressed? How about heartbroken or homesick? Animal Madness takes these questions seriously, exploring the topic of mental health and recovery in the animal kingdom and turning up lessons that Publishers Weekly calls “Illuminating…Braitman’s delightful balance of humor and poignancy brings each case of life….[Animal Madness’s] continuous dose of hope should prove medicinal for humans and animals alike.” Susan Orlean calls Animal Madness “a marvelous, smart, eloquent book—as much about human emotion as it is about animals and their inner lives.” It is “a gem…that can teach us much about the wildness of our own minds” (Psychology Today).

    Yet today there is only one—homo sapiens. What happened to the others? And what may happen to us?In this first volume of the full-color illustrated adaptation of his groundbreaking book, renowned historian Yuval Harari tells the story of humankind’s creation and evolution, exploring the ways in which biology and history have defined us and enhanced our understanding of what it means to be “human.” From examining the role evolving humans have played in the global ecosystem to charting the rise of empires, Sapiens challenges us to reconsider accepted beliefs, connect past developments with contemporary concerns, and view specific events within the context of larger ideas. Featuring 256 pages of full-color illustrations and easy-to-understand text covering the first part of the full-length original edition, this adaptation of the mind-expanding book furthers the ongoing conversation as it introduces Harari’s ideas to a wide new readership.

    Its sweeping synthesis casts fresh light on our new forms of marriage and family, on today's dramatic changes in business and economics. It explains the role of cults, the new definitions of work, play, love, and success. It points toward new forms of twenty-first-century democracy.