Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu's deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what’s to come.Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government’s role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts.Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people—and warns us that it may be many more years before we are able to conquer it for good.

    But it has also been a place of refuge for those fleeing persecution, never more so than before and after the Russian Revolution and the fall of the Romanov dynasty. For years, Russian aristocrats had enjoyed all that Belle Époque Paris had to offer, spending lavishly when they visited. It was a place of artistic experimentation, such as Diaghilev’s Ballets Russes. But the brutality of the Bolshevik takeover forced Russians of all types to flee their homeland, sometimes leaving with only the clothes on their backs.Arriving in Paris, former princes could be seen driving taxicabs, while their wives who could sew worked for the fashion houses, their unique Russian style serving as inspiration for designers like Coco Chanel. Talented intellectuals, artists, poets, philosophers, and writers struggled in exile, eking out a living at menial jobs. Some, like Bunin, Chagall and Stravinsky, encountered great success in the same Paris that welcomed Americans like Fitzgerald and Hemingway. Political activists sought to overthrow the Bolshevik regime from afar, while double agents from both sides plotted espionage and assassination. Others became trapped in a cycle of poverty and their all-consuming homesickness for Russia, the homeland they had been forced to abandon. This is their story.

    Liberated from home and hearth by World War I, politically enfranchised and ready to work, women arrived to take their place in the dazzling new skyscrapers of Manhattan. But they did not want to stay in uncomfortable boarding houses. They wanted what men already had—exclusive residential hotels with maid service, workout rooms, and private dining. Built in 1927, at the height of the Roaring Twenties, the Barbizon Hotel was designed as a luxurious safe haven for the “Modern Woman” hoping for a career in the arts. Over time, it became the place to stay for any ambitious young woman hoping for fame and fortune. Sylvia Plath fictionalized her time there in The Bell Jar, and, over the years, it’s almost 700 tiny rooms with matching floral curtains and bedspreads housed, among many others, Titanic survivor Molly Brown; actresses Grace Kelly, Liza Minnelli, Ali MacGraw, Jaclyn Smith; and writers Joan Didion, Gael Greene, Diane Johnson, Meg Wolitzer. Mademoiselle magazine boarded its summer interns there, as did Katharine Gibbs Secretarial School its students and the Ford Modeling Agency its young models. Before the hotel’s residents were household names, they were young women arriving at the Barbizon with a suitcase and a dream. Not everyone who passed through the Barbizon’s doors was destined for success—for some, it was a story of dashed hopes—but until 1981, when men were finally let in, the Barbizon offered its residents a room of their own and a life without family obligations. It gave women a chance to remake themselves however they pleased; it was the hotel that set them free. No place had existed like it before or has since. “Poignant and intriguing” (The New Republic), The Barbizon weaves together a tale that has, until now, never been told. It is both a vivid portrait of the lives of these young women looking for something more and a “brilliant many-layered social history of women’s ambition and a rapidly changing New York through the 20th century” (The Guardian).

    Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague—an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species.Unleashing new divisions in our society as well as opportunities for cooperation, this 21st-century pandemic has upended our lives in ways that will test, but not vanquish, our already frayed collective culture. Featuring new, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, Apollo's Arrow envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

    In Unacceptable, veteran Wall Street Journal reporters Melissa Korn and Jennifer Levitz trace the wiretapped calls, covert payments, and blatant deceit that brought the feds to Beverly Hills mansions and Upper East Side apartments, their residents all linked by one man: college whisperer and ultimate hustler Rick Singer.The shocking tale at the heart of Unacceptable is how, over decades, the charismatic Singer easily exploited a system rigged against regular people. Exploring the status obsession that seduced entitled parents in search of an edge, Korn and Levitz detail a scheme that eventually entangled more than fifty conspirators--a catalog of wealth and privilege that included CEOs, lawyers, real-estate developers, financiers, and famous actresses, mingling in jail cells and courtrooms.Detailing Singer's steady rise and dramatic fall, woven with stories of key players in the case, Unacceptable exposes the ugly underbelly of elite college admissions as a game with no rule book--paid-off proctors and storied college coaches turning a blind eye, helicopter parents and coddled teens spinning lies--opening loopholes and side doors into America's most exclusive institutions.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    Before Edward Snowden’s infamous data breach, the largest theft of government secrets was committed by an ingenious traitor whose intricate espionage scheme and complex system of coded messages were made even more baffling by his dyslexia. His name is Brian Regan, but he came to be known as The Spy Who Couldn’t Spell. In December of 2000, FBI Special Agent Steven Carr of the bureau’s Washington, D.C., office received a package from FBI New York: a series of coded letters from an anonymous sender to the Libyan consulate, offering to sell classified United States intelligence. The offer, and the threat, were all too real. A self-proclaimed CIA analyst with top secret clearance had information about U.S. reconnaissance satellites, air defense systems, weapons depots, munitions factories, and underground bunkers throughout the Middle East. Rooting out the traitor would not be easy, but certain clues suggested a government agent with a military background, a family, and a dire need for money. Leading a diligent team of investigators and code breakers, Carr spent years hunting down a dangerous spy and his cache of stolen secrets. In this fast-paced true-life spy thriller, Yudhijit Bhattacharjee reveals how the FBI unraveled Regan’s strange web of codes to build a case against a man who nearly collapsed America's military security.

    It’s about the greatest pirate in history, the most powerful executive in the music business, a revolutionary invention and an illegal website four times the size of the iTunes Music Store. Journalist Stephen Witt traces the secret history of digital music piracy, from the German audio engineers who invented the mp3, to a North Carolina compact-disc manufacturing plant where factory worker Dell Glover leaked nearly two thousand albums over the course of a decade, to the high-rises of midtown Manhattan where music executive Doug Morris cornered the global market on rap, and, finally, into the darkest recesses of the Internet.Through these interwoven narratives, Witt has written a thrilling book that depicts the moment in history when ordinary life became forever entwined with the world online — when, suddenly, all the music ever recorded was available for free. In the page-turning tradition of writers like Michael Lewis and Lawrence Wright, Witt’s deeply-reported first book introduces the unforgettable characters—inventors, executives, factory workers, and smugglers—who revolutionized an entire artform, and reveals for the first time the secret underworld of media pirates that transformed our digital lives.An irresistible never-before-told story of greed, cunning, genius, and deceit, How Music Got Free isn’t just a story of the music industry—it’s a must-read history of the Internet itself.

    Leana Wen likes to use. You don’t know it because good public health is invisible. It becomes visible only in its absence, when it is underfunded and ignored, a bitter truth laid bare as never before by the devastation of COVID-19.Leana Wen—emergency physician, former Baltimore health commissioner, CNN medical analyst, and Washington Post contributing columnist—has lived on the front lines of public health, leading the fight against the opioid epidemic, outbreaks of infectious disease, maternal and infant mortality, and COVID-19 disinformation. Here, in gripping detail, Wen lays bare the lifesaving work of public health and its innovative approach to social ills, treating gun violence as a contagious disease, for example, and racism as a threat to health.Wen also tells her own uniquely American story: an immigrant from China, she and her family received food stamps and were at times homeless despite her parents working multiple jobs. That child went on to attend college at thirteen, become a Rhodes scholar, and turn to public health as the way to make a difference in the country that had offered her such possibilities.Ultimately, she insists, it is public health that ensures citizens are not robbed of decades of life, and that where children live does not determine whether they live.

    For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family’s spoons, tried on their underpants and tested their chamber pots.Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions. Women wore makeup made with mercury and lead. Men rubbed turds on their bald spots. Physicians prescribed mercury enemas, arsenic skin cream, drinks of lead filings, and potions of human fat and skull, fresh from the executioner. The most gorgeous palaces were little better than filthy latrines. Gazing at gorgeous portraits of centuries past, we don’t see what lies beneath the royal robes and the stench of unwashed bodies; the lice feasting on private parts; and worms nesting in the intestines.In The Royal Art of Poison, Eleanor Herman combines her unique access to royal archives with cutting-edge forensic discoveries to tell the true story of Europe’s glittering palaces: one of medical bafflement, poisonous cosmetics, ever-present excrement, festering natural illness, and, sometimes, murder.

    He asked them to disclose something that, for scientific reasons, worries them—particularly scenarios that aren't on the popular radar yet. Encompassing neuroscience, economics, philosophy, physics, psychology, biology, and more—here are 150 ideas that will revolutionize your understanding of the world.Steven Pinker uncovers the real risk factors for war * Mihaly Csikszentmihalyi peers into the coming virtual abyss * Nobel laureate Frank Wilczek laments our squandered opportunities to prevent global catastrophe * Seth Lloyd calculates the threat of a financial black hole * Alison Gopnik on the loss of childhood * Nassim Nicholas Taleb explains why firefighters understand risk far better than economic "experts" * Matt Ridley on the alarming re-emergence of superstition * Daniel C. Dennett and george dyson ponder the impact of a major breakdown of the Internet * Jennifer Jacquet fears human-induced damage to the planet due to "the Anthropocebo Effect" * Douglas Rushkoff fears humanity is losing its soul * Nicholas Carr on the "patience deficit" * Tim O'Reilly foresees a coming new Dark Age * Scott Atran on the homogenization of human experience * Sherry Turkle explores what's lost when kids are constantly connected * Kevin Kelly outlines the looming "underpopulation bomb" * Helen Fisher on the fate of men * Lawrence Krauss dreads what we don't know about the universe * Susan Blackmore on the loss of manual skills * Kate Jeffery on the death of death * plus J. Craig Venter, Daniel Goleman, Virginia Heffernan, Sam Harris, Brian Eno, Martin Rees, and more

     Once one of Silicon Valley’s greatest success stories, Facebook has been under constant fire for the past five years, roiled by controversies and crises. It turns out that while the tech giant was connecting the world, they were also mishandling users’ data, spreading fake news, and amplifying dangerous, polarizing hate speech. The company, many said, had simply lost its way. But the truth is far more complex. Leadership decisions enabled, and then attempted to deflect attention from, the crises. Time after time, Facebook’s engineers were instructed to create tools that encouraged people to spend as much time on the platform as possible, even as those same tools boosted inflammatory rhetoric, conspiracy theories, and partisan filter bubbles. And while consumers and lawmakers focused their outrage on privacy breaches and misinformation, Facebook solidified its role as the world’s most voracious data-mining machine, posting record profits, and shoring up its dominance via aggressive lobbying efforts. Drawing on their unrivaled sources, Sheera Frenkel and Cecilia Kang take readers inside the complex court politics, alliances and rivalries within the company to shine a light on the fatal cracks in the architecture of the tech behemoth. Their explosive, exclusive reporting led them to a shocking conclusion: The missteps of the last five years were not an anomaly but an inevitability—this is how Facebook was built to perform. In a period of great upheaval, growth has remained the one constant under the leadership of Mark Zuckerberg and Sheryl Sandberg. Both have been held up as archetypes of uniquely 21st century executives—he the tech “boy genius” turned billionaire, she the ultimate woman in business, an inspiration to millions through her books and speeches. But sealed off in tight circles of advisers and hobbled by their own ambition and hubris, each has stood by as their technology is coopted by hate-mongers, criminals and corrupt political regimes across the globe, with devastating consequences. In An Ugly Truth, they are at last held accountable.

    Journalists flocked to the region to extract sympathetic profiles of families devastated by poverty, abandoned by establishment politics, and eager to consume cheap campaign promises. What You Are Getting Wrong About Appalachia is a frank assessment of America’s recent fascination with the people and problems of the region. The book analyzes trends in contemporary writing on Appalachia, presents a brief history of Appalachia with an eye toward unpacking Appalachian stereotypes, and provides examples of writing, art, and policy created by Appalachians as opposed to for Appalachians. The book offers a must-needed insider’s perspective on the region.

    Now, twenty years later, Queen Elizabeth II is in her mid-nineties, Prince Charles is in his seventies, and all eyes are turned increasingly toward William and Harry again. Andersen picks up where he left off, covering everything that has happened to the brothers as they have grown up, gotten married to two remarkable women, and had children—all while facing continual waves of controversy and questions about the ways their relationship has shifted.Andersen examines how the Queen’s behind-the-scenes maneuvering to mold her grandsons in the Windsor image after Diana’s death, and her expectations of William as the future king, played out. He questions whether the brothers’ famously close relationship can survive Harry’s departure from the Royal Family—the first time this has happened since their great-great-uncle King Edward abdicated the throne to marry a divorcée. He delves into the impact sisters-in-law Kate and Meghan have had on each other as well as on their princes, and how marriage and fatherhood have changed the brothers and in some ways also driven a wedge between them. Andersen also looks with an honest eye at how the princes and their wives have been continuously buffeted by scandal—including headline-making allegations of bullying, racism, betrayal, and emotional abuse that pushed more than one royal to the brink of self-destruction.Based on in-depth research and with his “fascinating and insightful” (The Christian Science Monitor) writing, Christopher Andersen leaves no stone unturned in this intimate and riveting look into the private lives of the world’s most famous princes.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.