This book was originally written by third-year medical students searching for the perfect review book--not finding it on the market, they wrote it themselves! Now in its third edition, Step-Up to Medicine boils down the full scope of tested pathology in a single ingenious tool. Each element is tailored for immediate content absorption, and an all-new, full-color interior differentiate elements for even faster, more efficient review. And, Step-Up to Medicine , third edition provides two types of self-assessment--the kinds of questions you will ask yourself as a clinician plus USMLE-style practice questions. This review book gives you just the Step-Up to the medicine clerkship, accompanying shelf exams, and USMLE Step 2 that you need! NEW Features for this blockbuster edition: Full-color, updated interior design brings the content to you in a rousing, memorable style. Full-color, updated art program illustrates concepts when a picture says it best--plenty of clinical images also supplement topics. New content on evidence-based medicine keeps you current and informed to guide your clinical decision making. Expanded content on drug dosing is added where relevant.CLASSIC Features students swear by: Complete coverage of high-yield medical topics ensures you are test ready Clinical Pearls boxes help you "file away" clinical medicine connections for handy retrieval at test time Quick Hits glimmering in the margins highlight highly testable material--just see how the sparks fly at test timeBONUS Material and study resources: eBook with the fully searchable text is available via thePoint . NEW 300 USMLE-style questions provide another means of self-assessment and practice for those exams NEW Audio clips of breath and heart sounds also available on thePoint

    The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter. You'll get the latest coverage on regulatory T cells, biology of the Th17 subset of CD4+ T cells, and more. The full-color artwork, comprehensive glossary, and clinical cases are just some of the features that reinforce and test your understanding of how the immune system functions. Student Consult online access lets you search the full text online and pursue further study through integration links. Covers the most up-to-date immunology information including regulatory T cells, and biology of the Th17 subset of CD4+ T cells to keep you completely current. Features integration links through included STUDENT CONSULT access for more in-depth study. Relates basic science to clinical disorders through clinical cases for better application in a real-world setting. Provides a full Glossary to keep you on the cutting edge of immunologic terminology. Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Presents beautiful full-color artwork for enhanced visual learning.

    Other bestselling works of neurobiology and the mind have focused on mental illness and abnormal behaviors—like the Oliver Sacks classic, The Man Who Mistook His Wife for a Hat—but The Other Side of Normal is an eye-opening, thought-provoking, utterly fascinating and totally accessible exploration of the universals of human experience. It will change forever our understanding of who we are and what makes us that way.

    It includes even more new monographs and the latest FDA approvals. This updated edition is a book that students can count on with vital information for Peds, as well as precautions for all vulnerable populations. From pediatrics to geriatrics and from pregnancy to breast feeding considerations, "Davis's Drug Guide for Nurses" addresses the entire lifespan.

    In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms for medicines. An understanding of pharmaceutics is therefore vital to all pharmacists and pharmaceutical scientists who are involved in converting a drug or a potential drug into a medicine that can be delivered safely, efficiently and conveniently to the patient.Professor Aulton's Pharmaceutics has become established as the clearest, most comprehensive textbook on this subject. The book provides pharmacy and pharmaceutical science students with the latest information on all aspects of pharmaceutics.provides a logical, comprehensive account of drug design and manufactureincludes the science of formulation and drug deliverydesigned and written for newcomers to the design of dosage formstwo new chapters on the principles and practice of sterilizationdosage-form design and delivery material thoroughly updatedproduct stability and stability testing of medicinal products section totally rewritten and expanded to include more of the relevant chemistryreflects current and future use of biotechnology products throughoutchanges in our understanding of biopharmaceutics, certain areas of drug delivery and the significance of the solid state all reflectednew page size and designnew photographs of equipment and apparatus

    When Dr Ben Goldacre saw someone on daytime TV dipping her feet in an 'Aqua Detox' footbath, releasing her toxins into the water, turning it brown, he thought he'd try the same at home. 'Like some kind of Johnny Ball cum Witchfinder General', using his girlfriend's Barbie doll, he gently passed an electrical current through the warm salt water. It turned brown. In his words: 'before my very eyes, the world's first Detox Barbie was sat, with her feet in a pool of brown sludge, purged of a weekend's immorality.' Dr Ben Goldacre is the author of the Bad Science column in the Guardian. His book is about all the 'bad science' we are constantly bombarded with in the media and in advertising. At a time when science is used to prove everything and nothing, everyone has their own 'bad science' moments from the useless pie-chart on the back of cereal packets to the use of the word 'visibly' in cosmetics ads.

    Warren Andiman, an HIV/AIDS researcher who has been on the front lines battling infectious diseases for over forty years. In Animal Viruses and Humans: A Narrow Divide, Andiman traces the history of eight zoonotic viruses —deadly microbes that have made the leap directly from animals to human populations: Middle East Respiratory Syndrome (MERS), Swine influenza, Hantavirus, Monkeypox, Severe Acute Respiratory Syndrome (SARS), Rabies, Ebola, and Henipaviruses (Nipah and Hendra). He also illustrates the labor intensive and fascinating detective work that infectious disease specialists must do to uncover the source of an outbreak.Andiman also looks to the future, envisioning the effects on zoonoses (diseases caused by zoonotic viruses) of climate change, microenvironmental damage, population shifts, and globalization. He reveals the steps that we can, and must, take to stem the spread of animal viruses, explaining, “The zoonoses I've chosen to write about . . . are meant to describe only a small sample of what is already out there but, more menacingly, what is inevitably on its way, in forms we can only imagine.” Warren Andiman, MD is professor emeritus of pediatrics and epidemiology at the Yale Schools of Medicine and Public Health.

    Beginning with the above questions, she began informally researching every affliction that she encountered in humans to learn whether it happened with animals, too. And usually, it did: dinosaurs suffered from brain cancer, koalas can catch chlamydia, reindeer seek narcotic escape in hallucinogenic mushrooms, stallions self-mutilate, and gorillas experience clinical depression. Natterson-Horowitz and science writer Kathryn Bowers have dubbed this pan-species approach to medicine zoobiquity. Here, they present a revelatory understanding of what animals can teach us about the human body and mind, exploring how animal and human commonality can be used to diagnose, treat, and heal patients of all species.

    To love and loathe the fox is a British condition."The fox is our apex predator, our most beautiful and clever killer. We have witnessed its wild touch, watched it slink by bins at night and been chilled by its high-pitched scream. And yet we long to stroke the tumbling cubs outside their tunnel homes and watch the vixen stalk the cornfield.There is something about foxes. They captivate us like no other species.Exploring a long and sometimes complicated relationship, The Wild Life of the Fox captures our love – and sometimes loathing – of this magnificent creature in vivid detail and lyrical prose.

    The emphasis is, instead, on the myriad ways in which the universe presents itself to us--and how, as observers and participants in its processes, we respond to it. "Life, like a dome of many-colored glass," wrote Percy Bysshe Shelley, "stains the white radiance of eternity." The author seeks here to explore the variety that gives life its beauty.Taken from Dyson's recent public lectures--delivered to audiences with no specialized knowledge in hard sciences--the book begins with a consideration of the practical and political questions surrounding biotechnology. As he seeks how best to explain the place of life in the universe, Dyson then moves from the ethical to the purely scientific. The book concludes with an attempt to understand the implications of biology for philosophy and religion.The pieces in this collection touch on numerous disciplines, from astronomy and ecology to neurology and theology, speaking to the lay reader as well as to the scientist. As always, Dyson's view of human nature and behavior is balanced, and his predictions of a world to come serve primarily as a means for thinking about the world as it is today.

    It follows a more quantitative and design-oriented approach than other texts in the market, helping readers gain a better understanding of important concepts. They'll also discover how material properties relate to the process variables in a given process as well as how to perform manufacturing science and quantitative engineering analysis of manufacturing processes.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    And despite the advances of science, germs are challenging medicine in ways that were unimaginable ten years ago. No wonder the world is up in arms -- and using antibacterial soaps. From the common cold, E. coli, and Lyme disease to encephalitis, mad cow disease, and flesh-eating bacteria, Tierno takes readers on a historical survey of the microscopic world. Rebuffing scare tactics behind recent "germ events" Tierno explains how the recycling of matter is the key to life. Yes, he'll tell you why it's a good idea to clean children's toys, why those fluffy towels may not be so clean, and why you never want to buy a second-hand mattress, but he also reveals that there is a lot we can do to prevent germ-induced suffering. You'll never look at anything the same way again.

    Drawing on new translations of Mutis's nearly forgotten writings, this fascinating story of scientific adventure in eighteenth-century South America retrieves Mutis's contributions from obscurity.In 1760, the 28-year-old Mutis—newly appointed as the personal physician of the Viceroy of the New Kingdom of Granada—embarked on a 48-year exploration of the natural world of northern South America. His thirst for knowledge led Mutis to study the region's flora, become a professor of mathematics, construct the first astronomical observatory in the Western Hemisphere, and amass one of the largest scientific libraries in the world. He translated Newton's writings and penned essays about Copernicus; lectured extensively on astronomy, geography, and meteorology; and eventually became a priest. But, as two-time Pulitzer Prize–winner Edward O. Wilson and Spanish natural history scholar José M. Gómez Durán reveal in this enjoyable and illustrative account, one of Mutis's most magnificent accomplishments involved ants.Acting at the urging of Carl Linnaeus—the father of taxonomy—shortly after he arrived in the New Kingdom of Granada, Mutis began studying the ants that swarmed everywhere. Though he lacked any entomological training, Mutis built his own classification for the species he found and named at a time when New World entomology was largely nonexistent. His unorthodox catalog of army ants, leafcutters, and other six-legged creatures found along the banks of the Magdalena provided a starting point for future study.Wilson and Durán weave a compelling, fast-paced story of ants on the march and the eighteenth-century scientist who followed them. A unique glance into the early world of science exploration, Kingdom of Ants is a delight to read and filled with intriguing information.

    This title is suitable for students preparing for careers in medicine, dentistry, nursing, and allied health, as well as research, teaching, and industry.