What makes you so different to your siblings? Why do you vote a certain way, remain faithful for twenty years, believe in God, love salads, be heterosexual, get cancer or depression, dislike sport or never put on weight? Using fascinating case studies of identical twins, Tim Spector draws gems from his exhaustive research project that has spanned twenty years to show how even real-life 'clones' with the same upbringing turn out in reality to be very different. Based on cutting-edge discoveries that are pushing the frontiers of our knowledge of genetics, he show us that - contrary to recent scientific teaching - nothing is completely hard-wired or pre-ordained. Challenging, enlightening and entertaining, Tim Spector explains theories such as why the Dutch have become the tallest nation in the world, why autism is more heritable than breast cancer and what could cause a fit and healthy man to have a heart attack within weeks of his overweight, heavy drinking, heavy smoking identical twin. Conceptually, he argues, we are not just skin and bones controlled by our genes but minds and bodies made of plastic. This plastic is dynamic - slowly changing shape and evolving, driven by many processes we still cannot comprehend. Many of the subtle differences between us appear now to be due to chance or fate, but as science rapidly evolves and explains current mysteries we will be able to become more active participants in this human moulding process. Then we can really begin to understand why we are who we are and what makes each of us so unique and quintessentially human.

    Hilarious, horrifying and heartbreaking, this diary is everything you wanted to know – and more than a few things you didn't – about life on and off the hospital ward. As seen on ITV's Zoe Ball Book Club This edition includes extra diary entries and a new afterword by the author.

    “Interweaving memoir, case histories, and accounts of new therapies, Riley anatomizes what is still a fairly young science, and a troubled one” (The New Yorker). Reporting on the field of global mental health from its colonial past to the present day, Riley highlights a range of scalable therapies, including how a group of grandmothers stands on the frontline of a mental health revolution. Hopeful, fascinating, and profound, A Cure for Darkness is “recommended reading for anyone with even a peripheral interest in depression” (Washington Examiner).

    To the public eye, medical stories often begin with sirens and flashing lights and culminate in survival or death. But these are only the most visible narratives. As a critical care doctor treating people at their sickest, Daniela Lamas is fascinated by a different story: what comes after for those whose lives are extended by days, months, or years as a result of our treatments and technologies?In You Can Stop Humming Now, Lamas explores the complex answers to this question through intimate accounts of patients and their families. A grandfather whose failing heart has been replaced by a battery-operated pump; a salesman who found himself a kidney donor on social media; a college student who survived a near-fatal overdose and returned home, alive but not the same; and a young woman navigating an adulthood she never thought she'd live to see -- these moving narratives paint a detailed picture of the fragile border between sickness and health.

    Neil Spector, one of the nation's top oncologists, led a charmed life. He was educated at prestigious universities, trained at top medical centers, and had married the woman of his dreams. It seemed too perfect. And it was.In 1994, it all came crashing down. He and his wife lost two unborn children. And a mysterious illness brought him to the brink of death. In his compelling memoir, Gone in a Heartbeat, Dr. Spector describes in great detail how he was misdiagnosed and, despite being a medical insider, was often discounted by his fellow physicians.As he recounts his own unorthodox approach to medicine and physician/patient relationships, Dr. Spector encourages readers to never surrender their power to a third party. He tells of courageous patients who served as role models, he conceded that doctors do a disservice to patients when "we treat them like statistics," and he advocates for educated patients who can make informed decisions collaboratively and not simply follow instructions. In Dr. Spector's words: "To recognize that we are in control of our own bodies and destinies can be a powerful step toward true healing."Readers of Gone in a Heartbeat will never view the medical profession the same again.

    Ever the teacher, in his last year, as his battle with the fatal illness amyotrophic lateral sclerosis (ALS), or Lou Gehrig's Disease, gradually weakened him, he appeared on three memorable "Nightline" programs with Ted Koppel, simply titled "Morrie," and captivated millions of viewers across the country with his spirit and compassion.Before he died, Morrie finished the manuscript for this book, which was originally titled Letting Go. He saw it as his greatest teaching opportunity. Whether you or a loved one is healthy or ill, young or old, there is invaluable wisdom here that can enrich your life. From "handling frustration" and "reaching acceptance" to "relating to others" and "being kind to yourself," Morrie's life-affirming insights help you take stock of where you are now and where you may want to be. Morrie: In His Own Words will have a lasting impact on whoever reads it. It is Morrie's invaluable legacy to us all.

    At nine he started working on an original theory in astrophysics that experts believe may someday put him in line for a Nobel Prize, and at age twelve he became a paid researcher in quantum physics. But the story of Kristine’s journey with Jake is all the more remarkable because his extraordinary mind was almost lost to autism. At age two, when Jake was diagnosed, Kristine was told he might never be able to tie his own shoes. The Spark is a remarkable memoir of mother and son. Surrounded by “experts” at home and in special ed who tried to focus on Jake’s most basic skills and curtail his distracting interests—moving shadows on the wall, stars, plaid patterns on sofa fabric—Jake made no progress, withdrew more and more into his own world, and eventually stopped talking completely. Kristine knew in her heart that she had to make a change. Against the advice of her husband, Michael, and the developmental specialists, Kristine followed her instincts, pulled Jake out of special ed, and began preparing him for mainstream kindergarten on her own. Relying on the insights she developed at the daycare center she runs out of the garage in her home, Kristine resolved to follow Jacob’s “spark”—his passionate interests. Why concentrate on what he couldn’t do? Why not focus on what he could? This basic philosophy, along with her belief in the power of ordinary childhood experiences (softball, picnics, s’mores around the campfire) and the importance of play, helped Kristine overcome huge odds. The Barnetts were not wealthy people, and in addition to financial hardship, Kristine herself faced serious health issues. But through hard work and determination on behalf of Jake and his two younger brothers, as well as an undying faith in their community, friends, and family, Kristine and Michael prevailed. The results were beyond anything anyone could have imagined. Dramatic, inspiring, and transformative, The Spark is about the power of love and courage in the face of overwhelming obstacles, and the dazzling possibilities that can occur when we learn how to tap the true potential that lies within every child, and in all of us.

    The adventure begins during the author's formative years in medical school and takes the reader through two decades of thought-provoking rural and urban-based ER and family practice experiences. Humorously written in an engaging mash-up of formal prose and informal medical slang with a nod to pop culture and ancient mythology, Dude is a powerful book that is certain to please readers of all stripes.

    So we asked:What does yours mean to you? THE RESULT IS EXTRAORDINARY.Over 70 people have shared their stories. Powerful, funny, moving, this book is here to tell you:It's OK.With writing from: Adam Kay - Alastair Campbell - Alexis Caught - Ben Platt - Bryony Gordon - Candice Carty-Williams - Charlie Mackesy - Charly Cox - Chidera Eggerue - Claire Stancliffe - Davina McCall - Dawn O'Porter - Elizabeth Day - Elizabeth Uviebinené - Ella Purnell - Emilia Clarke - Emma Thompson - Eve Delaney - Fearne Cotton - Gabby Edlin - Gemma Styles - GIRLI (Milly Toomey) - Grace Beverley - Hannah Witton - Honey Ross - Hussain Manawer - Jack Rooke - James Blake - Jamie Flook - Jamie Windust - Jessie Cave - Jo Irwin - Jonah Freud - Jonny Benjamin - Jordan Stephens - Kai-Isaiah Jamal - Kate Weinberg - Kelechi Okafor - Khalil Aldabbas - KUCHENGA - Lauren Mahon - Lena Dunham - Maggie Matic - Martha Lane Fox - Mathew Kollamkulam - Matt Haig - Megan Crabbe - Michael Kitching - Michelle Elman - Miranda Hart - Mitch Price - Mona Chalabi - Montana Brown - Nadia Craddock - Naomi Campbell - Poorna Bell - Poppy Jamie - Reggie Yates - Ripley Parker - Robert Kazandjian - Rosa Mercuriadis - Saba Asif - Sam Smith - Scarlett Curtis - Scarlett Moffatt - Scottee - Sharon Chalkin Feldstein - Shonagh Marie - Simon Amstell - Steve Ali - Tanya Byron - Travon Free - Yomi Adegoke - Yusuf Al Majarhi

    His new and initially intimidating classmates were high achievers from the Ivy League and other elite universities around the nation. Stern pulls back the curtain on the intense and emotionally challenging lessons he and his fellow doctors learned while studying the human condition, and ultimately, the value of connection. The narrative focuses on these residents, their growth as doctors, and the life choices they make as they try to survive their grueling four-year residency. Most importantly, as they study how to help distressed patients in search of a better life, they discover the meaning of failure and the preciousness of success.

    Author of the popular momsieblog.com, she leads and presents workshops on both writing and addiction, with a special emphasis on being a woman in recovery while parenting young children.

    An acclaimed expose that has already helped reform Olympic sports—now updated to reflect the latest developments in women's gymnastics and figure skating—it continues to plead for sanity, safety, and an end to our national obsession: winning at any cost.

    Drug-dependent and mentally ill, but desperate to keep hold of her daughter, Alice's mother snatches her from her parents' house and disappears.Cathy spends three anxious days worrying about her whereabouts before Alice is found safe, but traumatised. Alice is like a little doll, so young and vulnerable, and she immediately finds her place in the heart of Cathy's family. She talks openly about her mummy, who she dearly loves, and how happy she was living with her maternal grandparents before she was put into care. Alice has clearly been very well looked after and Cathy can't understand why she couldn't stay with her grandparents.It emerges that Alice's grandparents are considered too old (they are in their early sixties) and that the plan is that Alice will stay with Cathy for a month before moving to live with her father and his new wife. The grandparents are distraught – Alice has never known her father, and her grandparents claim he is a violent drug dealer.Desperate to help Alice find the happy home she deserves, Cathy's parenting skills are tested in many new ways. Finally questions are asked about Alice's father suitability, and his true colours begin to emerge.

    No new cells. No major changes. If you grew up depressed, angry, sad, aggressive, or nasty, you'd be that way for life. And, as you grew older, there'd be nowhere to go but down, as disease, age, or injury wiped out precious, irreplaceable brain cells. But over the past five, ten, twenty years, all that's changed. Using fMRI and PET scanning technology, neuroscientists can now look deep inside the human brain and they've discovered that it's amazingly flexible, resilient, and plastic. Pictures of the Mind: What the New Neuroscience Tells Us About Who We Are shows you what they've discovered and what it means to all of us. Through author Miriam Boleyn-Fitzgerald's masterfully written narrative and use stunning imagery, you'll watch human brains healing, growing, and adapting to challenges. You'll gain powerful new insights into the interplay between environment and genetics, begin understanding how people can influence their own intellectual abilities and emotional makeup, and understand the latest stunning discoveries about coma and "locked-in" syndrome. You'll learn about the tantalizing discoveries that may lead to cures for traumatic brain injury, stroke, emotional disorders, PTSD, drug addiction, chronic pain, maybe even Alzheimer's. Boleyn-Fitzgerald shows how these discoveries are transforming our very understanding of the "self," from an essentially static entity to one that can learn and change throughout life and even master the art of happiness.

    In What We Don't Talk About When We Talk About Fat, Aubrey Gordon unearths the cultural attitudes and social systems that have led to people being denied basic needs because they are fat and calls for social justice movements to be inclusive of plus-sized people's experiences. Unlike the recent wave of memoirs and quasi self-help books that encourage readers to love and accept themselves, Gordon pushes the discussion further towards authentic fat activism, which includes ending legal weight discrimination, giving equal access to health care for large people, increased access to public spaces, and ending anti-fat violence. As she argues, I did not come to body positivity for self-esteem. I came to it for social justice.By sharing her experiences as well as those of others--from smaller fat to very fat people--she concludes that to be fat in our society is to be seen as an undeniable failure, unlovable, unforgivable, and morally condemnable. Fatness is an open invitation for others to express disgust, fear, and insidious concern. To be fat is to be denied humanity and empathy. Studies show that fat survivors of sexual assault are less likely to be believed and less likely than their thin counterparts to report various crimes; 27% of very fat women and 13% of very fat men attempt suicide; over 50% of doctors describe their fat patients as awkward, unattractive, ugly and noncompliant; and in 48 states, it's legal--even routine--to deny employment because of an applicant's size.Advancing fat justice and changing prejudicial structures and attitudes will require work from all people. What We Don't Talk About When We Talk About Fat is a crucial tool to create a tectonic shift in the way we see, talk about, and treat our bodies, fat and thin alike.