Best of
Genetics

2012

Finding Family: My Search for Roots and the Secrets in My DNA


Richard Hill - 2012
    This fascinating quest, including the author's landmark use of DNA testing, takes readers on an exhilarating roller-coaster ride and concludes with a twist that rivals anything Hollywood has to offer.In the vein of a classic mystery, Hill gathers the seemingly scant evidence surrounding the circumstances of his birth. As his resolve shores up, the author also avails of new friends, genealogists, the Internet, and the latest DNA tests in the new field of genetic genealogy. As he closes in on the truth of his ancestry, he is able to construct a living, breathing portrait of the young woman who was faced with the decision to forsake her rights to her child, and ultimately the man whose identity had remained hidden for decades.Finding Family offers guidance, insight, and motivation for anyone engaged in a similar mission, from ways to obtain information to the many networks that can facilitate adoption searches. The book includes a detailed guide to DNA and genetic genealogy and how they can produce irrefutable results in determining genetic connections and help adoptees bypass sealed records and similar stumbling blocks.

The Violinist's Thumb: And Other Lost Tales of Love, War, and Genius, as Written by Our Genetic Code


Sam Kean - 2012
    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

The Double Helix: Annotated and Illustrated


James D. Watson - 2012
    At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

Dead Trees


Eli Constant - 2012
    They hunt in darkness, dragging bodies into tunnels teeming with primitive life. Elise is a widowed mother trying to keep her daughters alive, but bloody battles with beasties define survival road. Even when Elise finds Jason – a strong, capable man – she feels no safer, no more confident that her babies will see a tomorrow. Barely staying alive becomes the norm.Against all odds, Elise and her group reach a sanctuary. Yet there is no rest for the weary.Doctors O’Toole and Peters have been experimenting on the humanoid monsters… but they aren’t interested in saving humanity. Elise assists them reluctantly, all the while working secretly with Nick and Jamie to return the world to what it once was—Before the undergrounders came out to play on the surface. (Dead Trees is a classic dystopian, post-apocalyptic, Sci-Fi novel. It contains scenes of graphic violence, mild romantic elements, and some foul language).-------------------Reader Comments: "I must congratulate you on what looks to be a well crafted story. Well written, too. You have obviously put a lot of thought and effort into your writing and it shows." -John P. Authonomy Reviewer"What a nice change from zombies, vampires, trolls, aliens and giant earthworms. Quadruped humanoids who eat their dead are certainly monstrous enough to qualify for the role of abomination bent on killing off humankind. Your protagonist, Elise, using the first person POV makes the narrative introspective and immediate- a sympathetic character worth cheering on from one impossible situtation to the next. The dialogue is to the point, even raw at times, but always true to character. Thank you so much for the intriguing read." -Ken E.L. Authonomy Reviewer"I'm à huge fan of sci-fi and the occasional zombie stories. Though this didn't have zombies per se, there was the same feel to it. With very few inconsistencies, it was a story that can keep you interested in finding out what happens next. Whenever you think things are becoming "normal," it gets the adrenaline rushing all over again. It was nice to have a strong female lead in the story! I can easily see this being made into a movie. Very entertaining and I was sorry to have it end." Donna Davis - Amazon Reviewer

My Sister Rosalind Franklin


Jenifer Glynn - 2012
    Much has been written about the importance of her part, and about how her work was affected by her position as a woman scientist. Above all she was a distinguished scientist, not only in her work on DNA, but also in her earlier work on coals and carbons and in her later work on viruses. In this family memoir her sister, the writer and historian Jenifer Glynn, paints a full picture of Rosalind's life. Looking at Rosalind's background; her early education, her time as a science student at Cambridge, and her relations with her family, to her life as an adult and her time in Paris and at King's, Glynn shows how much her sister achieved and how she was influenced by the social and intellectual climate of the period she worked in.

Fundamentals of Cognitive Neuroscience: A Beginner's Guide


Bernard J. Baars - 2012
    Winner of a 2013 Most Promising New Textbook Award from the Text and Academic Authors Association, this book was written by two leading experts in the field to be highly accessible to undergraduates with limited neuroscience training. It covers all aspects of the field--the neural framework, sight, sound, consciousness, learning/memory, problem solving, speech, executive control, emotions, socialization and development--in a student-friendly format with extensive pedagogy and ancillaries to aid both the student and professor.This introductory text takes a unique thematic approach, guiding students along a clear path to understand the latest findings whether or not they have a background in neuroscience. It includes case studies and everyday examples designed to help students understand the more challenging aspects of the material. It is richly illustrated with carefully selected color graphics to enhance understanding. Enhanced pedagogy highlights key concepts for the student and aids in teaching. Chapter outlines, study questions, glossary, and image collection are also available on the student's companion website. Ancillary support saves instructors time and facilitates learning; test questions, image collection, and lecture slides are available on the instructor's manual website.This book will be of interest to undergraduate students in Neuroscience, Psychology, and related disciplines that teach cognitive neuroscience.

Illustrated Guide to Home Biology Experiments: All Lab, No Lecture


Robert Bruce Thompson - 2012
    This hands-on introduction includes more than 30 educational (and fun) experiments that help you explore this fascinating field on your own. Perfect for middle- and high-school students and DIY enthusiasts, this full-color guide teaches you the basics of biology lab work and shows you how to set up a safe lab at home.The Illustrated Guide to Home Biology Experiments is also written with the needs of homeschoolers firmly in mind, as well as adults who are eager to explore the science of nature as a life-long hobby. To get the most from the experiments, we recommend using this guide in conjunction with a standard biology text, such as the freely downloadable CK-12 Biology (ck-12.org).Master the use of the microscope, including sectioning and stainingBuild and observe microcosms, soda-bottle worlds of pond lifeInvestigate the chemistry of life from simple acids, bases, and buffers to complex carbohydrates, proteins, lipids, enzymes, and DNAExtract, isolate, and observe DNAExplore photosynthesis, osmosis, nitrogen fixation, and other life processesInvestigate the cell cycle (mitosis and cytokinesis)Observe populations and ecosystems, and perform air and water pollution testsInvestigate genetics and inheritanceDo hands-on microbiology, from simple culturing to micro-evolution of bacteria by forced selectionGain hands-on lab experience to prepare for the AP Biology examThrough their company, The Home Scientist, LLC (thehomescientist.com/biology), the authors also offer inexpensive custom kits that provide specialized equipment and supplies you’ll need to complete the experiments. Add a microscope and some common household items and you’re good to go.

The Science of Consequences: How They Affect Genes, Change the Brain, and Impact Our World


Susan M. Schneider - 2012
    While it's easy enough to see that consequences are important (where would we be without positive reinforcement?), few have heard there's a science of consequences, with principles that affect us every day. What's more, nature and nurture always work together, and learning often drives the flexibility in the system - routinely modifying our neurophysiology. Applications are everywhere, throughout everyday life, even helping fight prejudice, free addicts of their destructive habits, and treat depression. This science enriches the lives of pets and zoo animals, while also shedding light on our biggest societal challenges, where we must choose between short-term and long-term consequences. A unique and fascinating introduction to a science that is epic in scope.

Evolving: The Human Effect and Why It Matters


Daniel J. Fairbanks - 2012
    The author not only uses evidence from archaeology, geography, anatomy, biochemistry, radiometric dating, cell biology, chromosomes, and DNA to establish the inescapable conclusion that we evolved and are still evolving, he also explains in detail how health, food production, and human impact on the environment are dependent on our knowledge of evolution. This is essential reading for gaining a fuller appreciation of who we are, our place in the great expanse of life, and the importance of our actions.

Epigenetic Regulation in the Nervous System: Basic Mechanisms and Clinical Impact


J. David Sweatt - 2012
    The book spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system.Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions.Edited by the most highly regarded leaders in the field, this volume offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia. Presents a unified view of epigenetic mechanisms from behavior to genes and everything in betweenDiscusses clinically relevant disorders in the context of epigenetics research, making the volume appealing to clinicians as well as basic scientistsProvides numerous practical examples for the new investigator to facilitate implementation of research in neuroepigenetics

Reproductive Politics: What Everyone Needs to Know(r)


Rickie Solinger - 2012
    Wade-era power struggles over contraception and abortion, adoption and surrogacy, and other satellite issues. Forty years later, questions about reproductive rights are just as complex--and controversial--as they were then. Focusing mainly on the United States, Reproductive Politics: What Everyone Needs to Know(R) explores the legal, political, religious, social, ethical, and medical dimensions of this hotly contested arena.Tracing the historical roots of reproductive politics up through the present, Rickie Solinger considers a range of topics from abortion and contraception to health care reform and assisted reproductive technologies. Solinger tackles some of the most contentious questions up for debate today, including the definition of fetal personhood, and the roles poverty and welfare policy play in shaping reproductive rights. The answers she provides are informative, balanced, and sometimes quite surprising.Offering a wide range of information in an accessible and engaging manner, Reproductive Politics: What Everyone Needs to Know(R) orients readers and provides the knowledge necessary to follow the debates in this important and continually evolving field.What Everyone Needs to Know(R) is a registered trademark of Oxford University Press.