We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Linda Burfield Hazzard. It was supposed to be a holiday for the two sisters. But within a month of arriving at what the locals called Starvation Heights, the women were emaciated shadows of their former selves, waiting for death. They were not the first victims of Linda Hazzard, a quack doctor of extraordinary evil and greed who would stop at nothing short of murder to achieve her ambitions. As their jewelry disappeared and forged bank drafts began transferring their wealth to Hazzard’s accounts, Dora Williamson sent a last desperate plea to a friend in Australia, begging her to save them from the brutal treatments and lonely isolation of Starvation Heights.In this true story—a haunting saga of medical murder set in an era of steamships and gaslights—Gregg Olsen reveals one of the most unusual and disturbing criminal cases in American history.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    This text sets out to explain what life was like in the most immediate way, through taking the reader to the Middle Ages, and showing everything from the horrors of leprosy and war to the ridiculous excesses of roasted larks and haute couture.

    But Charlie wasn't lighting fires alone: he had an accomplice, his girlfriend Tonya Bundick. Through her depiction of the dangerous shift that happened in their passionate relationship, Hesse brilliantly brings to life the once-thriving coastal community and its distressed inhabitants, who had already been decimated by a punishing economy before they were terrified by a string of fires they could not explain. Incorporating this drama into the long-overlooked history of arson in the United States, American Fire re-creates the anguished nights that this quiet county spent lit up in flames, mesmerizingly evoking a microcosm of rural America - a land half gutted before the fires even began.

    In Will My Cat Eat My Eyeballs?, best-selling author and mortician Caitlin Doughty answers the most intriguing questions she’s ever received about what happens to our bodies when we die. In a brisk, informative, and morbidly funny style, Doughty explores everything from ancient Egyptian death rituals and the science of skeletons to flesh-eating insects and the proper depth at which to bury your pet if you want Fluffy to become a mummy. Now featuring an interview with a clinical expert on discussing these issues with young people—the source of some of our most revealing questions about death—Will My Cat Eat My Eyeballs? confronts our common fear of dying with candid, honest, and hilarious facts about what awaits the body we leave behind.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    He called it Ravensbrück, and during the years that followed thousands of people died there after enduring brutal forms of torture. All were women. There are a handful of studies and memoirs that reference Ravensbrück, but until now no one has written a full account of this atrocity, perhaps due to the mostly masculine narrative of war, or perhaps because it lacks the Jewish context of most mainstream Holocaust history. Ninety percent of Ravensbrück's prisoners were not Jewish. Rather, they were political prisoners, Resistance fighters, lesbians, prostitutes, even the sister of New York's Mayor LaGuardia. In a perverse twist, most of the guards were women themselves. Sarah Helm's groundbreaking work sheds much-needed light on an aspect of World War II that has remained in the shadows for decades. Using research into German and newly opened Russian archives, as well as interviews with survivors, Helm has produced a landmark achievement that weaves together various accounts, allowing us to follow characters on both sides of the prisoner/guard divide. Chilling, compelling, and deeply unsettling, Ravensbrück is essential reading for anyone concerned with Nazi history.

    Yet this is the first book to tell the story of rain. Cynthia Barnett's  Rain begins four billion years ago with the torrents that filled the oceans, and builds to the storms of climate change. It weaves together science—the true shape of a raindrop, the mysteries of frog and fish rains—with the human story of our ambition to control rain, from ancient rain dances to the 2,203 miles of levees that attempt to straitjacket the Mississippi River. It offers a glimpse of our "founding forecaster," Thomas Jefferson, who measured every drizzle long before modern meteorology. Two centuries later, rainy skies would help inspire Morrissey’s mopes and Kurt Cobain’s grunge. Rain is also a travelogue, taking readers to Scotland to tell the surprising story of the mackintosh raincoat, and to India, where villagers extract the scent of rain from the monsoon-drenched earth and turn it into perfume. Now, after thousands of years spent praying for rain or worshiping it; burning witches at the stake to stop rain or sacrificing small children to bring it; mocking rain with irrigated agriculture and cities built in floodplains; even trying to blast rain out of the sky with mortars meant for war, humanity has finally managed to change the rain. Only not in ways we intended. As climate change upends rainfall patterns and unleashes increasingly severe storms and drought, Barnett shows rain to be a unifying force in a fractured world. Too much and not nearly enough, rain is a conversation we share, and this is a book for everyone who has ever experienced it.

    Their father had gone to sea the previous Friday, the boys told their neighbours, and their mother was visiting her family in Liverpool. Over the next ten days Robert and Nattie spent extravagantly, pawning their parents' valuables to fund trips to the theatre and the seaside. But as the sun beat down on the Coombes house, a strange smell began to emanate from the building. When the police were finally called to investigate, the discovery they made sent the press into a frenzy of horror and alarm, and Robert and Nattie were swept up in a criminal trial that echoed the outrageous plots of the 'penny dreadful' novels that Robert loved to read. In The Wicked Boy, Kate Summerscale has uncovered a fascinating true story of murder and morality - it is not just a meticulous examination of a shocking Victorian case, but also a compelling account of its aftermath, and of man's capacity to overcome the past.

     While the Nazi party was being condemned by much of the world for burning books, they were already hard at work perpetrating an even greater literary crime. Through extensive new research that included records saved by the Monuments Men themselves—Anders Rydell tells the untold story of Nazi book theft, as he himself joins the effort to return the stolen books. When the Nazi soldiers ransacked Europe’s libraries and bookshops, large and small, the books they stole were not burned. Instead, the Nazis began to compile a library of their own that they could use to wage an intellectual war on literature and history. In this secret war, the libraries of Jews, Communists, Liberal politicians, LGBT activists, Catholics, Freemasons, and many other opposition groups were appropriated for Nazi research, and used as an intellectual weapon against their owners. But when the war was over, most of the books were never returned. Instead many found their way into the public library system, where they remain to this day. Now, Rydell finds himself entrusted with one of these stolen volumes, setting out to return it to its rightful owner. It was passed to him by the small team of heroic librarians who have begun the monumental task of combing through Berlin’s public libraries to identify the looted books and reunite them with the families of their original owners. For those who lost relatives in the Holocaust, these books are often the only remaining possession of their relatives they have ever held. And as Rydell travels to return the volume he was given, he shows just how much a single book can mean to those who own it.From the Hardcover edition.

    And yet, in our popular conception it exists largely as a footnote to World War I.In Pale Rider, Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain, and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered; and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.Laura Spinney writes that the Spanish flu was as significant – if not more so – as two world wars in shaping the modern world; in disrupting, and often permanently altering, global politics, race relations, family structures, and thinking across medicine, religion and the arts.

    When famed archaeologist Arthur Evans unearthed the ruins of a sophisticated Bronze Age civilization that flowered on Crete 1,000 years before Greece's Classical Age, he discovered a cache of ancient tablets, Europe's earliest written records. For half a century, the meaning of the inscriptions, and even the language in which they were written, would remain a mystery. Award-winning New York Times journalist Margalit Fox's riveting real-life intellectual detective story travels from the Bronze Age Aegean--the era of Odysseus, Agamemnon, and Helen--to the turn of the 20th century and the work of charismatic English archeologist Arthur Evans, to the colorful personal stories of the decipherers. These include Michael Ventris, the brilliant amateur who deciphered the script but met with a sudden, mysterious death that may have been a direct consequence of the decipherment; and Alice Kober, the unsung heroine of the story whose painstaking work allowed Ventris to crack the code.

    Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.