DMT: The Spirit Molecule


Rick Strassman - 2000
    Rick Strassman conducted US DEA-approved clinical research at the University of New Mexico in which he injected 60 volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical that is also manufactured by the human brain, consistently produced near-death and mystical experiences. Many volunteers reported convincing encounters with intelligent nonhuman presences, especially "aliens." Nearly all felt that the sessions were among the most profound experiences of their lives.Strassman's research connects DMT with the pineal gland, considered by Hindus to be the site of the seventh chakra and by René Descartes to be the seat of the soul. DMT: The Spirit Molecule makes the case that DMT, naturally released by the pineal gland, facilitates the soul's movement in and out of the body and is an integral part of the birth and death experiences, as well as the highest states of meditation and even sexual transcendence. Strassman also believes that alien abduction experiences are brought on by accidental releases of DMT. If used wisely, DMT could trigger a period of remarkable progress in the scientific exploration of the most mystical regions of the human mind and soul.

The Symbolic Species: The Co-evolution of Language and the Brain


Terrence W. Deacon - 1998
    Drawing on his breakthrough research in comparative neuroscience, Terrence Deacon offers a wealth of insights into the significance of symbolic thinking: from the co-evolutionary exchange between language and brains over two million years of hominid evolution to the ethical repercussions that followed man's newfound access to other people's thoughts and emotions.Informing these insights is a new understanding of how Darwinian processes underlie the brain's development and function as well as its evolution. In contrast to much contemporary neuroscience that treats the brain as no more or less than a computer, Deacon provides a new clarity of vision into the mechanism of mind. It injects a renewed sense of adventure into the experience of being human.

Lithium: A Doctor, a Drug, and a Breakthrough


Walter Brown - 2019
    And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization.From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again.Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

The Hidden Spring: A Journey to the Source of Consciousness


Mark Solms - 2021
    Scientists consider it the "hard problem" because it seems an impossible task to understand why we feel a subjective sense of self and how it arises in the brain.Venturing into the elementary physics of life, Solms has now arrived at an astonishing answer. In The Hidden Spring, he brings forward his discovery in accessible language and graspable analogies.Solms is a frank and fearless guide on an extraordinary voyage from the dawn of neuropsychology and psychoanalysis to the cutting edge of contemporary neuroscience, adhering to the medically provable. But he goes beyond other neuroscientists by paying close attention to the subjective experiences of hundreds of neurological patients, many of whom he treated, whose uncanny conversations expose much about the brain’s obscure reaches.Most importantly, you will be able to recognize the workings of your own mind for what they really are, including every stray thought, pulse of emotion, and shift of attention. The Hidden Spring will profoundly alter your understanding of your own subjective experience.

A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life


Ayelet Waldman - 2017
    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

Disconnected Kids: The Groundbreaking Brain Balance Program for Children with Autism, ADHD, Dyslexia, and Other Neurological Disorders


Robert Melillo - 2009
    Each year, an estimated 1.5 million children are diagnosed with autism, Asperger’s syndrome, ADHD, dyslexia, and obsessive-compulsive disorder. But even as rates rise, diagnosis and treatment have not changed in 50 years. Since psychiatric drugs, given to more than 20% of elementary school children today, don’t cure them, doctors tell parents these dysfunctions will never disappear. Enter Dr. Robert Melillo and his new understanding of the causes of these disorders: a disconnection between the left and right sides of the developing brain. His revolutionary Brain Balance™ program has achieved documented results, dramatically improving children’s and families’ quality of life. Since 1998, nearly 1,000 children have completed the Brain Balance™ program with remarkable success—behavioral, emotional, academic, and social. Written in an accessible style, Disconnected Kids shows parents how to use this drug- free approach at home, with customizable exercises for physical, sensory, and academic performance, advice for behavior modification, information on foods to avoid, and a follow-up program for lasting results.

A Smell of Burning: The Story of Epilepsy


Colin Grant - 2016
    His family broke down the door to find him unconscious on the floor. None of their lives were ever the same again. Christopher was diagnosed with epilepsy.A Smell of Burning tells the remarkable story of this strange and misunderstood disorder. How certain people, at a particular moment in their life, start to suffer seizures, often preceded by an aura, of which a smell of burning is one of the most common.For many years epilepsy was associated with mental illness or even possession by devils. People with epilepsy were forbidden to marry or have children. Many became victims of Nazi eugenics programmes. To this day many people with epilepsy – sixty million worldwide – still live in fear of exposure.Grant’s book traces the history of the condition and the pioneering doctors whose extraordinary breakthroughs finally helped gain an understanding of how the brain works. He tells the stories of famous people with epilepsy like Julius Caesar, Joan of Arc, Fyodor Dostoevsky and Vincent Van Gogh, and through the tragic tale of his brother, he considers the effect of epilepsy on his own life.

Permanent Present Tense: The Unforgettable Life of the Amnesic Patient, H. M.


Suzanne Corkin - 2012
    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients


Ben Goldacre - 2012
    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

NeuroLogic: The Brain's Hidden Rationale Behind Our Irrational Behavior


Eliezer J. Sternberg - 2016
      From bizarre dreams and hallucinations to schizophrenia and multiple personalities, the human brain is responsible for a diverse spectrum of strange thoughts and behaviors. When observed from the outside, these phenomena are often written off as being just “crazy,” but what if they were actually planned and logical?  NeuroLogic explores the brain’s internal system of reasoning, from its unconscious depths to conscious decision making, and illuminates how it explains our most outlandish as well as our most stereotyped behaviors. From sleepwalking murderers, contagious yawning, and the brains of sports fans to false memories, subliminal messages, and the secret of ticklishness, Dr. Eliezer Sternberg shows that there are patterns to the way the brain interprets the world—–patterns that fit the brain’s unique logic. Unraveling these patterns and the various ways they can be disturbed will not only alter our view of mental illness and supernatural experience, but will also shed light on the hidden parts of ourselves.  (With black-and-white illustrations throughout.)

Dragons of Eden: Speculations on the Evolution of Human Intelligence


Carl Sagan - 1977
    Dr Carl Sagan takes us on a great reading adventure, offering his vivid and startling insights into the brains of humans & beasts, the origin of human intelligence, the function of our most haunting legends and their amazing links to recent discoveries.

Bipolar Disorder Demystified: Mastering the Tightrope of Manic Depression


Lana R. Castle - 2003
    In Bipolar Disorder Demystified, author Lana Castle, who has lived the better part of her life with this illness, has turned her personal experience into an eloquent and useful guide to all those who travel down the same path. In clear and honest language, Castle helps readers understand the true nature of bipolar disorder, the factors that complicate its diagnosis, and strategies for coping with the illness. Bipolar Disorder Demystified makes great strides in dispelling the mystery surrounding this illness, helping readers decide if it's time to seek treatment, and providing those with any form of mood disorder the information they need to better manage their lives.

Consciousness: A Very Short Introduction


Susan Blackmore - 2003
    Consciousness: A Very Short Introduction challenges readers to reconsider key concepts such as personality, free will, and the soul. How can a physical brain create our experience of the world? What creates our identity? Do we really have free will? Could consciousness itself be an illusion? Exciting new developments in brain science are opening up these debates, and the field has now expanded to include biologists, neuroscientists, psychologists, and philosophers. This book clarifies the potentially confusing arguments and clearly describes the major theories, with illustrations and lively cartoons to help explain the experiments. Topics include vision and attention, theories of self, experiments on action and awareness, altered states of consciousness, and the effects of brain damage and drugs. This lively, engaging, and authoritative book provides a clear overview of the subject that combines the perspectives of philosophy, psychology, and neuroscience--and serves as a much-needed launch pad for further exploration of this complicated and unsolved issue.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

Sometimes Brilliant: The Impossible Adventure of a Spiritual Seeker and Visionary Physician Who Helped Conquer the Worst Disease in History


Larry Brilliant - 2015
    Sometimes Brilliant is the adventures of a philosopher, mystic, hippie, doctor, groundbreaking tech innovator, and key player in the eradication of one of the worst pandemics in human history. His story, of what happens when love, compassion and determination meet the right circumstances to effect positive change, is the kind that keeps hope and the sense of possibility alive.After sitting at the feet of Martin Luther King at the University of Michigan in 1963, Larry Brilliant was swept up into the civil rights movement, marching and protesting across America and Europe. As a radical young doctor he followed the hippie trail from London over the Khyber Pass with his wife Girija, Wavy Gravy and the Hog Farm commune to India. There, he found himself in a Himalayan ashram wondering whether he had stumbled into a cult. Instead, one of India’s greatest spiritual teachers, Neem Karoli Baba, opened Larry’s heart and told him his destiny was to work for the World Health Organization to help eradicate killer smallpox. He would never have believed he would become a key player in eliminating a 10,000-year-old disease that killed more than half a billion people in the 20th century alone.Brilliant’s unlikely trajectory, chronicled in Sometimes Brilliant, has brought him into close proximity with political leaders, spiritual masters, cultural heroes, and titans of technology around the world—from the Grateful Dead to Mikhail Gorbachev, from Ram Dass, the Dalai Lama, Lama Govinda, and Karmapa to Steve Jobs and the founders of Google, Salesforce, Facebook, Microsoft and eBay and Presidents Carter, Clinton, Bush and Obama. Anchored by the engrossing account of the heroic efforts of the extraordinary people involved in smallpox eradication in India, this is a riveting and fascinating epidemiological adventure, an honest reckoning of an entire generation, and a deeply moving spiritual memoir. It is a testament to faith, love, service, and what it means to engage with life’s most important questions in pursuit of a better, more brilliant existence.

When the Brain Can't Hear: Unraveling the Mystery of Auditory Processing Disorder


Teri James Bellis - 2002
    Teri James Bellis, one of the world's leading authorities on auditory processing disorder (APD), explains the nature of this devastating condition and provides insightful case studies that illustrate its effect on the lives of its sufferers.Millions of Americans struggle silently with APD. For many of them, holding a simple conversation can be next to impossible. As sound travels through an imperfect auditory pathway, words become jumbled, distorted, and unintelligible. As Dr. Bellis notes, the most profound impact of this highly specific impediment to auditory comprehension may be on the young. Facing a severely reduced ability to read, spell, comprehend, and communicate, children with APD are subject to anxiety, academic failure, and a damaged sense of self. Often, they are misdiagnosed. Discussing the latest and most promising clinical advances and treatment options, and providing a host of proven strategies for coping, Dr. Bellis takes much of the mystery out of APD. If you or anyone you know has difficulty comprehending spoken language, or if your child is struggling in school, this important book may have the answers you need.