Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free).THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

    If you have ever been frustrated by failure after failure to count calories, this dietary approach is for you. Dr. Ludwig's approach allows calories to work for you. Dr. Ludwig goes into detail of how he has scientifically discovered the fact that not all calories are equal.Through a series of three phases the Always Hungry eating plan allows the dieter to conquer the cravings that always sabotage the best diet plans on the market. This is not a one week diet trip that you will jump off at first trouble, rather, this is a three phase life journey that will enhance your life and free you from eating foods (even food thought to be good like low-fat foods) that hold your body hostage.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    A twentieth anniversary edition of Pauling's seminal work on the role of vitamins and minerals in preventing disease and achieving optimal health.

    She documents how the low-fat nutrition advice of the past sixty years has amounted to a vast uncontrolled experiment on the entire population, with disastrous consequences for our health.For decades, we have been told that the best possible diet involves cutting back on fat, especially saturated fat, and that if we are not getting healthier or thinner it must be because we are not trying hard enough. But what if the low-fat diet is itself the problem? What if the very foods we’ve been denying ourselves—the creamy cheeses, the sizzling steaks—are themselves the key to reversing the epidemics of obesity, diabetes, and heart disease?In this captivating, vibrant, and convincing narrative, based on a nine-year-long investigation, Teicholz shows how the misinformation about saturated fats took hold in the scientific community and the public imagination, and how recent findings have overturned these beliefs. She explains why the Mediterranean Diet is not the healthiest, and how we might be replacing trans fats with something even worse. This startling history demonstrates how nutrition science has gotten it so wrong: how overzealous researchers, through a combination of ego, bias, and premature institutional consensus, have allowed dangerous misrepresentations to become dietary dogma.With eye-opening scientific rigor, The Big Fat Surprise upends the conventional wisdom about all fats with the groundbreaking claim that more, not less, dietary fat—including saturated fat—is what leads to better health and wellness. Science shows that we have been needlessly avoiding meat, cheese, whole milk, and eggs for decades and that we can now, guilt-free, welcome these delicious foods back into our lives.

    It's embedded in our DNA. Our diet has changed dramatically over the past ten thousand years, but our genetic blueprint has not -- our bodies are not designed to process the types of food we are fed today. It's like putting diesel fuel into a regular car -- it just won't work. And making matters worse is the fact that diets don't work either: less than 6 percent of weight-loss attempts succeed. The average person who goes on a diet actually gains five pounds. But a medical revolution is under way, finally showing us precisely how the powerful forces that keep weight on can actually be reprogrammed to automatically burn fat and keep weight off for good. The concept is simple. By learning how to work with our bodies instead of against them, we can ignite the natural fat-burning furnaces that lie dormant within us. For the first time ever, Dr. Mark Hyman makes this new science of weight loss available to the general public. This medical revolution is based on a groundbreaking concept called nutrigenomics -- the science of how food talks to our genes. This science is actually startlingly simple. Food contains information and instructions for our bodies -- eat the right foods and send instructions of weight loss and health; eat the wrong foods and send messages of weight gain and disease. After spending the last ten years conducting pioneering, hands-on research with over two thousand patients at Canyon Ranch, one of the world's leading health resorts, Dr. Hyman has discovered the seven fundamental causes of obesity. While fad diets have identified one or two of these causes, never before have they all been integrated into a single, simple plan for automatic weight loss -- this is the promise of "UltraMetabolism." "UltraMetabolism" is an easy-to-follow eight-week plan to help you lose weight based on your own unique genetic needs. Since each of our bodies is different and may require more or less of certain nutrients to awaken our fat-burning DNA, Dr. Hyman shows you exactly how to customize the program for your own particular needs. The program includes menus, recipes, and shopping lists, as well as recommendations for supplements and exercise and lifestyle treatments designed to create a healthy metabolism -- an "UltraMetabolism" -- permanent weight loss, and lifelong health.Ultrametabolism Testimonials..".I lost 50 pounds and have kept it off for 4 years.""The last five years have become the healthiest years of my life. Because of Dr. Hyman's program, I have an in-depth understanding of my physical condition and have tailored a weight loss program for my needs. Since following his plan, I've significantly reduced my cholesterol from 240 to 160. In addition, I lost 50 pounds and have kept it off for 4 years."-- Joseph Bernstein Milwaukee, WI"I've dropped 2 dress sizes (so far)...Dr. Hyman literally gave me my life back.""Over the past few years I had gained 70 lbs and felt progressively worse as I bounced from doctor to doctor without any real answers for my weight gain, my migraines, or my many other ailments. Dr. Hyman helped me understand how many of my health issues were due to food allergies. Lab tests showed I was allergic to 28 different foods! I started on the DeTox phase of Dr. Hymans program and within 3 weeks, I lost 11 pounds and my swollen wrists and puffy face went away. I used to wake up extremely exhausted, but now I wake up at 6 am and maintain a constant level of energy throughout the day. No other program gave me a means to discover the real source of my problems. Now I have the energy to play with my 8-year-old and 11-year-old children. My entire family is finally eating healthier, and I've dropped 2 dress sizes (so far!) Dr Hyman literally gave me my life back."-- Audrey Meyer Lampert North Granby, CT"The menu was easy to implement, in spite of my hectic lifestyle...""Through Dr. Hyman's program, I not only dropped my cholesterol from 335 to below 200, but I lost 20 lbs and have kept if off for the last 2 years through his instructions including a specific meal plan, exercise, and supplements. The menu was easy to implement, in spite of my hectic lifestyle and easy to adapt when I traveled to hotels and restaurants. Matter of fact, I went from a pant size of 38 to a 36 and needed to buy a lot of new clothes."-- Cavas Gobhai Cambridge, MA"It was easy! All I needed to do was follow his instructions; in the first 30 days I lost 21 pounds.""Substituting simple foods with other healthy foods that I love helped me lose the cravings for all the junk I used to eat. Dr. Hyman's weight loss program gave me a lot of information about my body. It was easy! All I needed to do was follow his instructions; in the first 30 days I lost 21 pounds. I feel better than I have in 10 years and can now walk up the stairs without losing my breath. I forgot how good I could I feel."-- Deede Dominick Phippsburg, Maine"I was ready for a change, and Dr. Hyman's program helped me prioritize my life.""After I quit smoking three years ago, I snacked a lot in order to forget about smoking. After doing that for 6 months, I gained almost 30 pounds. I was sick and tired of having no energy, and I wanted to feel good again. In addition, I love to shop, and I wanted to buy fancy clothes without having to shop at the big and tall store. I was ready for a change, and Dr. Hyman's program helped me prioritize my life. Since I started in 2003 I have lost over 60 pounds and have maintained the loss. In addition, I've gone from a size 18 to a size 10. When I look at old pictures, I realize that I feel and look better than I did 15 years ago."-- Margarida Glenhage Gothenburg Sweden..".I lost 30 lbs with no exercise.""As a single mother, I was tired of feeling sick all the time and decided to change my life so that I could become healthy for my 3%-year-old daughter. After relearning how to feed myself and my daughter, I lost 30 lbs with no exercise from June to December and I dropped my cholesterol 105 points."-- Nancy Grey DC Bronxville, NY"I lost 30 lbs, went back to a size 4, and no longer have migraines.""After going through an 8-month period of being very sick with hives, having extreme inflammation in my face, and gaining 30 pounds, I found Dr. Hyman's program. Because I went through his simple plan, I uncovered that I am allergic to gluten, the protein in wheat, which was the source of all my problems. After getting on his plan, I lost 30 lbs, went back to a size 4, and no longer have migraines. My husband even noticed the change and went on the program too; so far, he's lost 45 pounds."-- Debbie Gosney Charlotte, NC..".it's easy to jump back on when I occasionally fall off...""This program gave me the satisfaction of being in control of my body and life. I've maintained my 18-pound weight loss since 2002, reduced my glucose levels from 170 to 102, and taken control over my diabetes to the point where I no longer have any symptoms. Going on a program like this is like a religious conversion; it's easy to jump back on when I occasionally fall off and I have more energy than I've ever had. At the age of 71, I run 4 miles a day and feel great."

    Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind—from his brain to his fingertips to his abs.From the bestselling author of The Year of Living Biblically and The Know-It-All comes the true and truly hilarious story of one person’s quest to become the healthiest man in the world. Hospitalized with a freak case of tropical pneumonia, goaded by his wife telling him, “I don’t want to be a widow at forty-five,” and ashamed of a middle-aged body best described as “a python that swallowed a goat,” A.J. Jacobs felt compelled to change his ways and get healthy. And he didn’t want only to lose weight, or finish a triathlon, or lower his cholesterol. His ambitions were far greater: maximal health from head to toe. The task was epic. He consulted an army of experts— sleep consultants and sex clinicians, nutritionists and dermatologists. He subjected himself to dozens of different workouts—from Strollercize classes to Finger Fitness sessions, from bouldering with cavemen to a treadmill desk. And he took in a cartload of diets: raw foods, veganism, high protein, calorie restriction, extreme chewing, and dozens more. He bought gadgets and helmets, earphones and juicers. He poked and he pinched. He counted and he measured. The story of his transformation is not only brilliantly entertaining, but it just may be the healthiest book ever written. It will make you laugh until your sides split and endorphins flood your bloodstream. It will alter the contours of your brain, imprinting you with better habits of hygiene and diet. It will move you emotionally and get you moving physically in surprising ways. And it will give you occasion to reflect on the body’s many mysteries and the ultimate pursuit of health: a well-lived life.

    Around the world, we struggle with diseases that were once considered rare. Cancer, heart disease, Alzheimer’s disease, and diabetes affect millions each year; many people are also struggling with hypertension, weight gain, fatty liver, dementia, low testosterone, menstrual irregularities and infertility, and more. We treat the symptoms, not realizing that all of these diseases and disorders have something in common. Each of them is caused or made worse by a condition known as insulin resistance. And you might have it. Odds are you do—over half of all adults in the United States are insulin resistant, with most other countries either worse or not far behind. In Why We Get Sick, internationally renowned scientist and pathophysiology professor Benjamin Bikman explores why insulin resistance has become so prevalent and why it matters. Unless we recognize it and take steps to reverse the trend, major chronic diseases will be even more widespread. But reversing insulin resistance is possible, and Bikman offers an evidence-based plan to stop and prevent it, with helpful food lists, meal suggestions, easy exercise principles, and more. Full of surprising research and practical advice, Why We Get Sick will help you to take control of your health.

    But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.

    Most patients with Hashimoto's will present with acid reflux, nutrient deficiencies, anemia, intestinal permeability, food sensitivities, gum disorders and hypoglycemia in addition to the "typical" hypothyroid symptoms such as weight gain, cold intolerance, hair loss, fatigue and constipation. The body becomes stuck in a vicious cycle of immune system overload, adrenal insufficiency, gut dysbiosis, impaired digestion, inflammation, and thyroid hormone release abnormalities. This cycle is self-sustaining and will continue causing more and more symptoms until an external factor intervenes and breaks the cycle apart. The lifestyle interventions discussed in this book aim to dismantle the vicious cycle piece by piece. We start with the simplest modifications, by removing triggers, and follow with repairing the other broken systems to restore equilibrium, allowing the body to rebuild itself.

    Jeffrey Bland has been on the cutting edge of Functional Medicine, which seeks to pinpoint and prevent the cause of illness, rather than treat its symptoms. Managing chronic diseases accounts for three quarters of our total healthcare costs, because we're masking these illnesses with pills and temporary treatments, rather than addressing their underlying causes, he argues. Worse, only treating symptoms leads us down the path of further illness.In The Disease Delusion, Dr. Bland explains what Functional Medicine is and what it can do for you. While advances in modern science have nearly doubled our lifespans in only four generations, our quality of life has not reached its full potential. Outlining the reasons why we suffer chronic diseases from asthma and diabetes to obesity, arthritis and cancer to a host of other ailments, Dr. Bland offers achievable, science-based solutions that can alleviate these common conditions and offers a roadmap for a lifetime of wellness.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    Natasha Campbell-McBride set up The Cambridge Nutrition Clinic in 1998. As a parent of a child diagnosed with learning difficulties, she was acutely aware of the difficulties facing other parents like her, and she has devoted much of her time to helping these families. She realised that nutrition played a critical role in helping children and adults to overcome their disabilities, and has pioneered the use of probiotics in this field.Her willingness to share her knowledge has resulted in her contributing to many publications, as well as presenting at numerous seminars and conferences on the subjects of learning disabilities and digestive disorders. Her book "Gut and Psychology Syndrome" captures her experience and knowledge, incorporating her most recent work.She believes that the link between learning disabilities, the food and drink that we take, and the condition of our digestive system is absolute, and the results of her work have supported her position on this subject. In her clinic, parents discuss all aspects of their child's condition, confident in the knowledge that they are not only talking to a professional but to a parent who has lived their experience. Her deep understanding of the challenges they face, puts her advice in a class of it's own.

    Renowned writer Meghan O’Rourke delivers a revelatory investigation into this elusive category of “invisible” illness that encompasses autoimmune diseases, post-treatment Lyme disease syndrome, and now long COVID, synthesizing the personal and the universal to help all of us through this new frontier. Drawing on her own medical experiences as well as a decade of interviews with doctors, patients, researchers, and public health experts, O’Rourke traces the history of Western definitions of illness, and reveals how inherited ideas of cause, diagnosis, and treatment have led us to ignore a host of hard-to-understand medical conditions, ones that resist easy description or simple cures. And as America faces this health crisis of extraordinary proportions, the populations most likely to be neglected by our institutions include women, the working class, and people of color. Blending lyricism and erudition, candor and empathy, O’Rourke brings together her deep and disparate talents and roles as critic, journalist, poet, teacher, and patient, synthesizing the personal and universal into one monumental project arguing for a seismic shift in our approach to disease. The Invisible Kingdom offers hope for the sick, solace and insight for their loved ones, and a radical new understanding of our bodies and our health.

    She has helped millions lose weight and feel great, and now she can help you, too.Bestselling author and Biggest Loser trainer Jillian Michaels swore she'd never write another diet book. But she realized that with all of the conflicting, overly complicated information being thrown at you each day, what you need is a clear, simple plan that cuts through all the confusion to deliver amazing results, fast. This book distills all she's learned about diet, fitness, and a healthy lifestyle to provide anyone seeking to be slim, strong, and healthy with an easier path to achieving dramatic body transformation.No nonsense, no gimmicks, just actionable advice that gets incredible results fast!