America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    On one side are parents, bombarded with stories about the dangers of vaccines, now wary of immunizing their sons and daughters. On the other side are doctors, scared to send kids out of their offices vulnerable to illnesses like whooping cough and measles--the diseases of their grandparents.How did anyone come to view vaccines with horror? The answer is rooted in one of the most powerful citizen activist movements in our nation's history. In Deadly Choices, infectious disease expert Paul Offit relates the shocking story of anti-vaccine America--its origins, leaders, influences, and impact. Offering strategies to keep us from returning to an era when children routinely died from infections, Deadly Choices is a vigorous and definitive rebuttal of the powerful anti-vaccine movement.

    For good.Feel Better in 5 is the first daily 5-minute plan that is easy to maintain, easy-to-follow and requires only the smallest amount of willpower.Top tips include:· A strength workout that you can do anywhere· Gut-boosting snacks you can eat on the go · Yoga moves to relax and stay supple · Breathing exercises to calm the mindDrawing on Dr Rangan Chatterjee's twenty years of experience and real-life case studies from his GP practice, Feel Better in 5 is your daily plan for a happier, healthier you at no extra cost.

    So, how can managers ensure that their businesses run as usual when the way that we work looks so … unusual?   Top business thought leader David Burkus has mined the very best research on virtual teams and case studies of companies that have not just survived but thrived through remote work to provide managers with the field guide to leading remotely, packed with everyday examples and illuminating insights. Structured around the lifecycle of working on a team, Burkus tackles the key inflection points and challenges that managers face in this new landscape from taking the team remote and adding new members, to communicating effectively and quickly, managing performance, keeping the team engaged, and celebrating individual departures or adjourning the team as a whole.   If you want your remote team to have a harmonious work-life balance while increasing productivity, this is your indispensable guide.

    Communities where heroin had never been seen before—from Charlotte, NC and Huntington, WVA, to Salt Lake City and Portland, OR—were overrun with it. Local police and residents were stunned. How could heroin, long considered a drug found only in the dense, urban environments along the East Coast, and trafficked into the United States by enormous Colombian drug cartels, be so incredibly ubiquitous in the American heartland? Who was bringing it here, and perhaps more importantly, why were so many townspeople suddenly eager for the comparatively cheap high it offered?With the same dramatic drive of El Narco and Methland, Sam Quinones weaves together two classic tales of American capitalism: The stories of young men in Mexico, independent of the drug cartels, in search of their own American Dream via the fast and enormous profits of trafficking cheap black-tar heroin to America’s rural and suburban addicts; and that of Purdue Pharma in Stamford, Connecticut, determined to corner the market on pain with its new and expensive miracle drug, Oxycontin; extremely addictive in its own right. Quinones illuminates just how these two stories fit together as cause and effect: hooked on costly Oxycontin, American addicts were lured to much cheaper black tar heroin and its powerful and dangerous long-lasting high. Embroiled alongside the suppliers and buyers are DEA agents, local, small-town sheriffs, and the US attorney from eastern Virginia whose case against Purdue Pharma and Oxycontin made him an enemy of the Bush-era Justice Department, ultimately stalling and destroying his career in public service.Dreamland is a scathing and incendiary account of drug culture and addiction spreading to every part of the American landscape.

    The chiefs of staff, often referred to as "the gatekeepers," wield tremendous power in Washington and beyond; they decide who is allowed to see the president, negotiate with Congress to push POTUS's agenda, and--most crucially--enjoy unparalleled access to the leader of the free world. Each chief can make or break an administration, and each president reveals himself by the chief he picks.Through extensive, intimate interviews with all seventeen living chiefs and two former presidents, award-winning journalist and producer Chris Whipple pulls back the curtain on this unique fraternity. In doing so, he revises our understanding of presidential history, showing us how James Baker's expert managing of the White House, the press, and Capitol Hill paved the way for the Reagan Revolution--and, conversely, how Watergate, the Iraq War, and even the bungled Obamacare rollout might have been prevented by a more effective chief.Filled with shrewd analysis and never-before-reported details, The Gatekeepers offers an essential portrait of the toughest job in Washington.

    Ultimately, the history of these challenges tells the story of humanity itself. Through an unforgettable cast of characters, Pulitzer Prize-winning author Richard Rhodes explains how wood gave way to coal and coal made room for oil, as we now turn to natural gas, nuclear power, and renewable energy. Rhodes looks back on five centuries of progress, through such influential figures as Queen Elizabeth I, King James I, Benjamin Franklin, Herman Melville, John D. Rockefeller, and Henry Ford. In Energy, Rhodes highlights the successes and failures that led to each breakthrough in energy production; from animal and waterpower to the steam engine, from internal-combustion to the electric motor. He addresses how we learned from such challenges, mastered their transitions, and capitalized on their opportunities. Rhodes also looks at the current energy landscape, with a focus on how wind energy is competing for dominance with cast supplies of coal and natural gas. He also addresses the specter of global warming, and a population hurtling towards ten billion by 2100. Human beings have confronted the problem of how to draw life from raw material since the beginning of time. Each invention, each discovery, each adaptation brought further challenges, and through such transformations, we arrived at where we are today. In Rhodes’s singular style, Energy details how this knowledge of our history can inform our way tomorrow.

    We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground.This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine.The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America’s most respected and admired science journalists.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    The End of Animal Farming pushes this conversation forward by outlining a strategic roadmap to a humane, ethical, and efficient food system in which slaughterhouses are obsolete—where the tastes of even the most die-hard meat eater are satisfied by innovative food technologies like cultured meats and plant-based protein. Social scientist Jacy Reese Anthis analyzes the social forces leading us toward the downfall of animal agriculture, the technology making this change possible for the meat-hungry public, and the activism driving consumer demand for plant-based and cultured foods.Reese contextualizes the issue of factory farming—the inhumane system of industrial farming that 95 percent of farmed animals endure—as part of humanity's expanding moral circle. Humanity increasingly treats nonhuman animals, from household pets to orca whales, with respect and kindness, and Reese argues that farmed animals are the next step. Reese applies an analytical lens of "effective altruism," the burgeoning philosophy of using evidence-based research to maximize one's positive impact in the world, in order to better understand which strategies can help expand the moral circle now and in the future.The End of Animal Farming is not a scolding treatise or a prescription for an ascetic diet. Reese invites readers—vegan and non-vegan—to consider one of the most important and transformational social movements of the coming decades.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Noted speaker, musician, and coach Barbara McAfee shows how to become a more effective communicator by mastering the full range of your voice and learning to match tone to content.

    The author, an internationally renowned gerontologist at Cornell University, offers sage advice from the oldest and wisest Americans on everything from finding a partner, to deciding to commit, to growing old together. Along the way, the book answers questions like these: How do you know if the person you love is the right one? What are the secrets for improving communication and reducing conflict? What gets you through the major stresses of marriage, such as child-rearing, work, money issues, and inlaws? From interviews with 700 elders, 30 Lessons for Loving offers unique wisdom that will enrich anyone’s relationship life, from people searching for the right partner to those working to keep the spark alive after decades together. Filled with great stories, wise observations, and useful advice, 30 Lessons for Loving is destined to become another classic.

    We strive for the absolute best in every aspect of our lives, ignoring what we do well naturally. Why do we measure our time in terms of efficiency instead of meaning? Why can't we just take a break?In Do Nothing, award-winning journalist Celeste Headlee illuminates a new path ahead, seeking to institute a global shift in our thinking so we can stop sabotaging our well-being, put work aside and start living instead of doing. The key lies in embracing what makes us human: our creativity, our social connections (Instagram doesn't count), our ability for reflective thought, and our capacity for joy. Celeste's strategies will allow you to regain control over your life and break your addiction to false efficiency, including:-Increase your time perception and determine how your hours are being spent. -Stop comparing yourself to others.-Invest in quality idle time. Take a hot bath and listen to music.-Spend face-to-face time with friends and familyIt's time to recover our leisure time and reverse the trend that's making us all sadder, sicker, and less productive.

    By identifying your fear triggers, releasing yourself from your past experiences, and acting on what you truly value, you can make courage a daily habit.Using a practical four-part program, you’ll learn to understand the emotions that arise when fears are triggered, and to pause and evaluate your emotional state before you act. You’ll discover how to listen without attachment to the self-defeating messages of your inner critic, understand the critic’s function, and implement respectful boundaries so that your inner voice no longer controls your behavior. You’ll reframe self-limiting life narratives that can—without conscious awareness—dictate your day-to-day decisions. And finally, you’ll nurture more authentic connections with family, friends, and community in order to find support and reinforce the life changes you’re making.If you feel like something is holding you back from landing your dream job, moving to a new city, having a satisfying love relationship, or simply taking advantage of all life has to offer—and if you have a sneaking suspicion that that something is you—then this one-of-a-kind guide will show you how to finally break free from self-doubt and start living your best life.