In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    Librarian note: an alternate cover for this edition can be found here.Michel Foucault examines the archeology of madness in the West from 1500 to 1800 – from the late Middle Ages, when insanity was still considered part of everyday life and fools and lunatics walked the streets freely, to the time when such people began to be considered a threat, asylums were first built, and walls were erected between the “insane” and the rest of humanity.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Doctors loathed this time-consuming procedure and for centuries relied on midwives. Later, they substituted the efficiency of mechanical devices, including the electric vibrator, invented in the 1880s. In The Technology of Orgasm, Rachel Maines offers readers a stimulating, surprising, and often humorous account of hysteria and its treatment throughout the ages, focusing on the development, use, and fall into disrepute of the vibrator as a legitimate medical device.

    In only a few decades, the capital grew from a compact Regency town into a sprawling metropolis of 6.5 million inhabitants, the largest city the world had ever seen. Technology--railways, street-lighting, and sewers--transformed both the city and the experience of city-living, as London expanded in every direction. Now Judith Flanders, one of Britain's foremost social historians, explores the world portrayed so vividly in Dickens' novels, showing life on the streets of London in colorful, fascinating detail. From the moment Charles Dickens, the century's best-loved English novelist and London's greatest observer, arrived in the city in 1822, he obsessively walked its streets, recording its pleasures, curiosities, and cruelties. Now, with him, Flanders leads us through the markets, transport systems, sewers, rivers, slums, alleys, cemeteries, gin palaces, chop-houses, and entertainment emporia of Dickens' London, to reveal the Victorian capital in all its variety, vibrancy, and squalor.

    From body lotion to tonic water, the popular new element shines bright in the otherwise dark years of the First World War.Meanwhile, hundreds of girls toil amidst the glowing dust of the radium-dial factories. The glittering chemical covers their bodies from head to toe; they light up the night like industrious fireflies. With such a coveted job, these "shining girls" are the luckiest alive—until they begin to fall mysteriously ill.But the factories that once offered golden opportunities are now ignoring all claims of the gruesome side effects, and the women's cries of corruption. And as the fatal poison of the radium takes hold, the brave shining girls find themselves embroiled in one of the biggest scandals of America's early 20th century, and in a groundbreaking battle for workers' rights that will echo for centuries to come.Written with a sparkling voice and breakneck pace, The Radium Girls fully illuminates the inspiring young women exposed to the "wonder" substance of radium, and their awe-inspiring strength in the face of almost impossible circumstances. Their courage and tenacity led to life-changing regulations, research into nuclear bombing, and ultimately saved hundreds of thousands of lives.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    With the rise of the ‘mad-doctor’ profession, English liberty seemed to be threatened by a new generation of medical men willing to incarcerate difficult family members in return for the high fees paid by an unscrupulous spouse or friend. And contrary to popular modern belief, the madwoman in the attic was at least as likely to have been a madman.Among the victims were the beautiful and charismatic Rosina, wife of the novelist Edward Bulwer-Lytton; Edward Davies, victim of a mother’s greed; Louisa Lowe, who paid for her religious fervour; and John Perceval, who, despite the best efforts of the abusive asylum attendants, cured himself.Sarah Wise uncovers twelve shocking stories, untold for over a century, which reveal the darker side of the Victorian upper and middle classes – their sexuality, fears of inherited madness, financial greed and fraudulence – and chillingly evoke the black motives at the heart of the phenomenon of the ‘inconvenient person’.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    With a muckraker's passion, Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. Tracing over three centuries of "cures" for madness, Whitaker shows how medical therapies have been used to silence patients and dull their minds. He tells of the eighteenth- and nineteenth-century practices of "spinning" the insane, extracting their teeth, ovaries, and intestines, and submerging patients in freezing water. The "cures" in the 1920s and 1930s were no less barbaric as eugenic attitudes toward the mentally ill led to brain-damaging lobotomies and electroshock therapy. Perhaps Whitaker's most damning revelation, however, is his report of how drug companies in the 1980s and 1990s skewed their studies in an effort to prove the effectiveness of their products. Based on exhaustive research culled from old patient medical records, historical accounts, numerous interviews, and hundreds of government documents, Mad in America raises important questions about our obligations to the mad, what it means to be "insane," and what we value most about the human mind.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    Among the most compelling and perplexing of these symptoms are the strange visual hallucinations and distortions of space, time, and body image which migraineurs sometimes experience. Portrayals of these uncanny states have found their way into many works of art, from the heavenly visions of Hildegard von Bingen to Alice in Wonderland. Dr. Oliver Sacks argues that migraine cannot be understood simply as an illness, but must be viewed as a complex condition with a unique role to play in each individual's life.

    The work is engaging, filled with interesting anecdotes and stories, and is an incredibly lively read on a thoroughly interesting subject much in need of a closer look. In breadth, the book ranges from biblical times to the present, and in sheer scale it attempts to present a unified series of images of the Western wife over the course of some 2,000 years. In doing so, Professor Yalom has presented us an interesting grid, well conceived and wonderfully written, with which we can begin to examine this cultural phenomenon.One of the main strengths of the work is its method: Yalom draws heavily on diaries, newspapers, journals, and personal letters, and she interweaves these with citations from the laws, general customs of the times, religious rites, and civic procedure. By moving in a very fluid way from the abstract to the particular, what we see emerging, in each era, is a lively picture of how the general affected the individual. The book makes it real, makes us wonder, and helps to recover for us so many of the lost voices of women over the centuries, silenced by the overshadowing "great men" approach to history. These are not so much the stories of "great women" as they are the telling of everyday life. In reading them we get a fuller sense of what the time and place may have been like for the women whose voices we are listening to. It is the dignity of these everyday voices that holds us, intrigues us, and invites us to read further. A History of the Wife links the ancient, the medieval, the Victorian, and the modern, and makes a strong historical and narrative case for its subject.Along the way, we are treated to many interesting insights, observations, and historical facts: Nero was officially married five times -- three times to women, twice to boys; until the Middle Ages, marriages in Catholic Europe often did not involve any ceremony at all, and "church weddings" do not appear on the scene until well into the evolution of Christian Europe. The role of women changes slowly in the West, and the role of religion, from the biblical period through early Christianity to the changes brought by the Reformation and the voyages to the New World, are mapped for us in a sweeping overview.A particularly strong section of the book is the documentation of the last 50 years of the cultural institution of marriage, and the vast changes brought by World War II and the cultural ferment of the '60s. This is made more impressive because of the compelling histories that the work recounts for us in the 2,000 years before our own era.An old adage maintained that "everyone needs a wife"; this lively book tells us who followed that adage, why and how they did so, and how we got to where we are now.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    They set the fashions, encouraged the arts, and, in some cases, ruled nations. Eleanor Herman's Sex with Kings takes us into the throne rooms and bedrooms of Europe's most powerful monarchs. Alive with flamboyant characters, outrageous humor, and stirring poignancy, this glittering tale of passion and politics chronicles five hundred years of scintillating women and the kings who loved them.Curiously, the main function of a royal mistress was not to provide the king with sex but with companionship. Forced to marry repulsive foreign princesses, kings sought solace with women of their own choice. And what women they were! From Madame de Pompadour, the famous mistress of Louis XV, who kept her position for nineteen years despite her frigidity, to modern-day Camilla Parker-Bowles, who usurped none other than the glamorous Diana, Princess of Wales.The successful royal mistress made herself irreplaceable. She was ready to converse gaily with him when she was tired, make love until all hours when she was ill, and cater to his every whim. Wearing a mask of beaming delight over any and all discomforts, she was never to be exhausted, complaining, or grief-stricken.True, financial rewards for services rendered were of royal proportions -- some royal mistresses earned up to $200 million in titles, pensions, jewels, and palaces. Some kings allowed their mistresses to exercise unlimited political power. But for all its grandeur, a royal court was a scorpion's nest of insatiable greed, unquenchable lust, and vicious ambition. Hundreds of beautiful women vied to unseat the royal mistress. Many would suffer the slings and arrows of negative public opinion, some met with tragic ends and were pensioned off to make room for younger women. But the royal mistress often had the last laugh, as she lived well and richly off the fruits of her "sins."From the dawn of time, power has been a mighty aphrodisiac. With diaries, personal letters, and diplomatic dispatches, Eleanor Herman's trailblazing research reveals the dynamics of sex and power, rivalry and revenge, at the most brilliant courts of Europe. Wickedly witty and endlessly entertaining, Sex with Kings is a chapter of women's history that has remained unwritten -- until now.