Turn to any page, and you'll find essential point-of-care guidance on all the major conditions seen in clinical medicine. Completely updated to reflect all the major advances and new clinical developments, the new edition of the Manual is the most indispensable yet. It continues to focus on diagnosis and therapy with an emphasis on patient care and offers authoritative, high-yield coverage of: Etiology and epidemiology Clinically relevant pathophysiology Signs & Symptoms o Differential Diagnosis Physical and Laboratory Findings Therapeutics o Practice GuidelinesNEW FEATURESFull-color presentation for the first time!Full-color images of clinical conditions encountered in dermatology, cardiology, and eye diseases New chapters on end-of-life care, congenital heart disease in the adult patient, non-invasive cardiac examination, and metabolic syndromeLook for these other great Harrison's titles:Harrison's Principles of Internal Medicine, 17eHarrison's Online available through Accessmedicine.com

    Many new or revised figures and photographs, study questions and a glossary of key terms have been added.

    Stop eating and training like one.Because most nutrition products and training plans are designed for men, it’s no wonder that so many female athletes struggle to reach their full potential. ROAR is a comprehensive, physiology-based nutrition and training guide specifically designed for active women. This book teaches you everything you need to know to adapt your nutrition, hydration, and training to your unique physiology so you can work with, rather than against, your female physiology. Exercise physiologist and nutrition scientist Stacy T. Sims, PhD, shows you how to be your own biohacker to achieve optimum athletic performance.Complete with goal-specific meal plans and nutrient-packed recipes to optimize body composition, ROAR contains personalized nutrition advice for all stages of training and recovery. Customizable meal plans and strengthening exercises come together in a comprehensive plan to build a rock-solid fitness foundation as you build lean muscle where you need it most, strengthen bone, and boost power and endurance. Because women’s physiology changes over time, entire chapters are devoted to staying strong and active through pregnancy and menopause. No matter what your sport is—running, cycling, field sports, triathlons—this book will empower you with the nutrition and fitness knowledge you need to be in the healthiest, fittest, strongest shape of your life.

    Many different therapists now use myofascial techniques to influence postural change and pain relief. This book demonstrates exactly how the muscles connect within the connect tissue to affect posture, compensatory strain, and pain patterns. The aim is to present scientifically sound and often complicated material in a way which can be easily learned, understood, and applied by those who do not necessarily have a scientific background. ANATOMY TRAINS is written and presented in a style that allows this new information on the myofascial system to be easily absorbed by a wide range of readers: from the student, athlete, or client to the most experienced therapist.Includes full-colour illustrations of 11 myofascial meridians and the rules for discovering other meridiansUses numerous two-colour charts and drawings to detail the muscular and fascial structures involved in the meridiansPresents information on assessment of structural and movement patterns and gives related applications to manual therapy and movement educationProvides a selection of techniques from the library of structural integrationIncludes an introduction to the fascial system as a whole, with new points-of-view and new research findings on the fascial system's responsesOffers a fun approach to learning essential structural anatomy, comparing the connective tissue system to a railway network

    One can trace its roots to the Calculus of Variations and the work of Euler and Lagrange. This natural and reasonable approach to mathematical programming covers numerical methods for finite-dimensional optimization problems. It begins with very simple ideas progressing through more complicated concepts, concentrating on methods for both unconstrained and constrained optimization.

    The first abnormal psychology book to present a thoroughly integrated multicultural perspective--based on the authors' view that cross-cultural comparisons can greatly enhance the understanding of disorders--the text provides extensive coverage and integration of multicultural models, explanations, and concepts. The book also helps you gain an understanding of abnormal behavior as scientific and clinical endeavors, while providing insight into the tools that mental health professionals use to study and treat disorders.

    Each chapter of An Introduction to Brain and Behavior explores a specific question asked by working neuroscientists and students (i.e. "Why do we have a brain?"  "How is the nervous system organized?").  This approach brings coherence to a vast subject, and helps students understand what information is important as their study of brain and behavior progresses chapter to chapter.

    The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing, The Haywire Heart presents the evidence that going too hard or too long can damage your heart forever. You’ll find what to watch out for, what to do about it, and how to protect your heart so you can enjoy the sports you love for years to come. The Haywire Heart shares the developing research into a group of conditions known as “athlete’s heart”, starting with a wide-ranging look at the warning signs, symptoms, and how to recognize your potential risk. Leading cardiac electrophysiologist and masters athlete Dr. John Mandrola explores the prevention and treatment of heart conditions in athletes like arrhythmia, atrial fibrillation and flutter, tachycardia, hypertrophy, and coronary artery disease. He reviews new research about exercise intensity and duration, recovery, inflammation and calcification, and the ways athletes inflict lasting harm. These heart problems are appearing with alarming frequency among masters athletes who are pushing their bodies harder than ever in the hope that exercise will keep them healthy and strong into their senior years. The book is complete with gripping case studies of elite and age-group athletes from journalist Chris Case—like the scary condition that nearly killed cyclist and coauthor Lennard Zinn—and includes a frank discussion of exercise addiction and the mental habits that prevent athletes from seeking medical help when they need it.Dr. Mandrola explains why many doctors misdiagnose heart conditions in athletes and offers an invaluable guide on how to talk with your doctor about your condition and its proven treatments. He covers known heart irritants, training and rest modifications, effective medicines, and safe supplements that can reduce the likelihood of heart damage from exercise. Heart conditions affect hardcore athletes as well as those who take up sports seeking better health and weight loss. The Haywire Heart is a groundbreaking and critically important guide to heart care for athletes. By protecting your heart now and watching for the warning signs, you can avoid crippling heart conditions and continue to exercise and compete for years to come.

    With the latest findings about the mental and physical benefits of exercise, personal stories from scientists and laypeople alike, as well as researched-based prescriptions for readers, Gretchen Reynolds shows what kind of exercise—and how much—is necessary to stay healthy, get fit, and attain a smaller jeans size. Inspired by Reynolds's wildly popular “Phys Ed” column for The New York Times, this book explains how exercise affects the body in distinct ways and provides the tools readers need to achieve their fitness goals, whether that's a faster 5K or staying trim.

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

    Exhibiting a combination of power, speed, and quickness, they've raised the bar on performance, competition, and training. Training for Speed, Agility, and Quickness is the complete workout guide you need in order to perform a step ahead of the competition.With this total training package, you'll have exclusive online access to a video library of the most effective drills and exercises for developing movement skills, and you'll see how to perform key tests and execute the best and most complex drills from the book. Sample training programs are included for these sports:Baseball and softballFootball and rugbyBasketball and netballCombat sportsTrack and fieldSoccerLacrosseTennis and badmintonRacquetball and squashThe top sport and conditioning experts present the best information on testing, techniques, drills, and training programs to maximize athletes' movement capabilities. The book includes 262 drills and proven assessments for customizing programs and tracking progress.If you're serious about elevating your performance, Training for Speed, Agility, and Quickness is a must have.PLEASE NOTE: This is not an official book from SAQ International. For details of books including SAQ Soccer and SAQ Rugby and official SAQ resources, please visit www.saqinternational.com.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a training group on my team could consist of five men who run next to one another, stride for stride, day after day, and nonetheless turn out five entirely different runners. How could this be?We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. Naturals. Or were they?The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training?The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research.In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called 10,000-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence.Along the way, Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not, and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components.This subject necessarily involves digging deep into sensitive topics like race and gender. Epstein explores controversial questions such as:Are black athletes genetically predetermined to dominate both sprinting and distance running, and are their abilities influenced by Africa’s geography?Are there genetic reasons to separate male and female athletes in competition?Should we test the genes of young children to determine if they are destined for stardom?Can genetic testing determine who is at risk of injury, brain damage, or even death on the field?Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

    Kinesiology of the Musculoskeletal System is the most comprehensive, research-based, reader-friendly text on kinesiology ever published. Beautifully and abundantly illustrated in two-color, this dynamic, accessible resource presents complex scientific information in an approach designed to draw the reader in and explore the fundamental principles of kinesiology of the trunk and extremities as well as in relation to joints, muscles, and biomechanics.Comprehensive coverage - not only of kinesiology of the trunk and extremitites, but also of the underlaying principles of kinesiology with respect to joints, muscles and biomechanics - explains the 'why?' as well as the 'how?'A definitive chapter on the kinesiology of human gait!Clear and reader-friendly, which is great for study and revision for students of all levelsSpecial Focus boxes throughout the text provide abundant clinical examples and gives the students a chance to probe deeper into the topicTopics at a Glanceat the beginning of each chapter, allow students with less time to quickly locate the essential informationOver 550 superb line-drawings - making difficult kinesiologic concepts easier to graspAppendices include glossary of key terms - a handy reference toolThe author has many years of experience in physical therapy - specifically kinesiology - and is a teacher, clinician and researcher.